scholarly journals Significance of iron levels in patients with non-cicatricial alopecias: a cross sectional study

2021 ◽  
Author(s):  
Jahnavi Sambangi ◽  
Bela Padhiar
Keyword(s):  
Serum Ferritin ◽  
Hair Loss ◽  
Serum Iron ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Mean Values ◽  
Pull Test ◽  
Low Serum ◽  
Male Pattern

<p class="abstract"><strong>Background: </strong>Among all the nutritional causes of hair loss, iron levels are found to be important key nutrient. Synthesis of hair involves many steps which require iron as a cofactor. The intention of present study is to evaluate relationship between iron and hair loss. The objectives of the study are to study the clinical patterns, demographic and epidemiological factors associated with hair loss and to find association between iron study parameter (Hb, serum iron, serum ferritin, TIBC) and hair loss.</p><p class="abstract"><strong>Methods: </strong>The study was a cross section- observational study, conducted among the patients with diagnosed non-cicatricial alopecias from June 2018 to April 2019. A total of 50 study participants were recruited. Specific investigations like hair pull test and trichogram were done. Chi square test was applied and p&lt;0.05 was considered significant.</p><p class="abstract"><strong>Results:</strong> Among the total 50 participants 35 (70%) were males and 15 (30%) were females. Mean (±SD) age was 44 (±9.5) years. Mean (SD) of haemoglobin, serum iron, TIBC and ferritin are 9.6 (±2.6), 75.5 (±50), 365 (±54) and 106 (±87) respectively. Trichogram result proves telogen hair- 22 (44%), dystrophic hair loss- 14 (28%) and anagen hair loss-14 (28%). Hair pull test was positive in 27 (54%). Higher proportion of male pattern hair loss was associated with lower haemoglobin and low serum ferritin levels. (p value -0.046, 0.031)</p><p class="abstract"><strong>Conclusions:</strong> Significant association was found between the diagnosis of non cicatricial alopecia and mean values of haemoglobin and serum ferritin with lower haemoglobin and low serum ferritin was mostly associated with male pattern hair loss.</p>

scholarly journals Tinnitus: The Sound of Stress?

2018 ◽  
Vol 14 (1) ◽  
pp. 264-269 ◽  
Author(s):  
Patricia Ciminelli ◽  
Sergio Machado ◽  
Manoela Palmeira ◽  
Mauro Giovanni Carta ◽  
Sarah Cristina Beirith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Progressive Increase ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Mean Values ◽  
Subjective Tinnitus ◽  
Stress Symptoms ◽  
The Impact

Background: Emotional stress is frequently associated with otologic symptoms as tinnitus and dizziness. Stress can contribute to the beginning or worsening of tinnitus. Objective: The objective of the study is to evaluate the presence of stress symptoms in patients with chronic, subjective tinnitus, and correlate its presence to annoyance associated with tinnitus. Methods: This is a cross-sectional study. One hundred and eighty patients with chronic, subjective tinnitus were included. Patients answered the Tinnitus Handicap Inventory (THI) to evaluate the impact of tinnitus in the quality of life and answered the Lipp's inventory symptoms of stress for adults (ISSL). The data obtained was organized using Excel® 2010, mean values, linear regression and p-value were calculated. Results: Of the 180 patients included in the study, 117 (65%) had stress symptoms, 52 of the 117 (44%) were in the resistance phase and 23 of the 117 (20%) in the exhaustion phase, the remaining was in the alert phase. There was a clear progressive increase in stress as THI raised, with more impact of tinnitus in quality of life. Conclusion: The presence of stress symptoms, measured by ISSL was observed in most of our patients with chronic subjective tinnitus, specially in the resistance and exhaustion phases and it is directly associated with tinnitus annoyance.

ROLE OF ABSOLUTE EOSINOPHIL COUNT AS A MODALITY OF INVESTIGATION IN SUSPECTED CASES OF HELMINTHIC INFESTATION IN CHILDREN AGED BETWEEN 5 TO 15 YEARS WITH COMPARISON TO STOOL ROUTINE AND MICROSCOPY

2021 ◽  
pp. 112-113
Author(s):  
Meghashree N ◽  
Rohini D ◽  
Mahendar Reddy M ◽  
A.M Koppad
Keyword(s):  
Eosinophil Count ◽  
Stool Specimen ◽  
Cross Sectional Study ◽  
Research Centre ◽  
P Value ◽  
College Hospital ◽  
Cross Sectional ◽  
Mean Values ◽  
Medical College ◽  
Absolute Eosinophil Count

Introduction: Eosinophilia is a well-known host immune response in helminthic infestation. This study was carried out to investigate whether a correlation exists between absolute eosinophil count in children with stool specimen positive for helminthic infestation. Aim And Objective: To determine average raised absolute eosinophil count in children who were having various helminthic infestation with stool specimen positive. Materials And Methods: A hospital based cross sectional study done at Navodaya medical college hospital and research centre during 2019 October to 2020 September for a period of 12 months. Both blood and stool samples were obtained from a total of 69 suspected children after examined, categorised into 2 groups. Among them 24 cases were positive of helminthic infestation and 45 cases were negative. T-test and descriptive statistics were used to analyse the data. Results: The study revealed that children infested with helminths found to have higher absolute eosinophil count (mean 4644/µl (95%CI; 3474-4212) than not infested (mean 801/µl (95%CI; 616-945) with p value <0.001. In this helminth's family; nematodes, trematodes, cestodes showed mean values of absolute eosinophil count were 5206/µl (4806-7151/µl), 4930/µl (4500-5382/µl) and 2179/µl (2500-1669/µl) respectively. Conclusions: Raised absolute eosinophil count has been observed in stool specimen positive cases of helminths, especially more in nematodes. Therefore, should be considered for a single dose of albendazole.

Evaluation of serum electrolyte levels in iron deficiency anemia patients.

2021 ◽  
Vol 28 (05) ◽  
pp. 691-696
Author(s):  
Maryam Rafiq ◽  
Amna Arooj ◽  
Qurrat-ul-Ain Tahir ◽  
Nudrat Fayyaz ◽  
Afra Samad ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Cross Sectional Study ◽  
Deficiency Anemia ◽  
Close Monitoring ◽  
Cross Sectional ◽  
Mean Values ◽  
Medical College ◽  
Complete Blood Counts

Objectives: To evaluate electrolytes levels in patients suffering from iron deficiency anemia and to compare it with patients without anemia. Study Design: Descriptive Cross Sectional study. Setting: Department of Pathology, Sahiwal Medical College Sahiwal. Period: November, 2019 to May, 2020. Material & Methods: After taking informed consent, five milliliter of blood was drawn from each patient. Blood sample was analyzed for electrolytes, complete blood counts and serum ferritin levels. Results were compared in normal and iron deficiency anemic groups. Results: A total of 287 clinically anemic suspects including 181 (63.0%) female and 106 (37.0%) male with mean age of patients as 36.11±12.23 were included in this study. A total of 205 (71.4%) of the suspects had anemia whereas frequency of anemia remained higher among females (78.5%) as compared to males (59.5%) in this study. On the basis of serum ferritin levels a total of 178 (62.0%) patients had iron deficiency. Mean values of Sodium (130.41±0.59) and Bicarbonate (24.10±0.31) remained low while mean Potassium (4.33±0.07) and Chloride (103.93±0.47) levels of Iron Deficiency Anemia (IDA) group remained high as compared to non-anemic group. Conclusion: Levels of sodium and bicarbonate are found to be on the lower side while potassium and chloride remained on higher side in patients with Iron deficiency Anemia in this study. Thus these findings indicate close monitoring of electrolytes to evade impediments during management of patients.

scholarly journals Effect of intravenous Deferoxamine concomitant use with blood transfusion on serum ferritin in thalassemia major patients

2017 ◽  
Vol 6 (2) ◽  
pp. 399
Author(s):  
Afshin Fathi ◽  
Firouz Amani ◽  
Samira Araghchin ◽  
Esmaeil Farzaneh
Keyword(s):  
Blood Transfusion ◽  
Serum Ferritin ◽  
Ferritin Level ◽  
Thalassemia Major ◽  
Cross Sectional Study ◽  
T Test ◽  
Cross Sectional ◽  
Mean Values ◽  
Baseline Values ◽  
Care Costs

Background: Subcutaneous Deferoxamineis often not tolerated by patients and its rejection leads to iron overload with its complications. So, other methods with better toleration and reduction of Deferoxamine consumption are necessary. The present study aimed to evaluate the effect of intravenous Deferoxamine infusion during blood transfusion on serum ferritin (SF) in thalassemia major patients.Methods: In a retrospective cross-sectional study, thirty four patients with β-thalassemia major treated with monthly blood transfusion at Bu-Ali hospital in Ardabil city from April 2013 to April 2014, were selected and followed for six months. The mean SF rate and the needed subcutaneous Deferoxamine rates before intervention were considered as baseline. All patients received intravenous Deferoxamine concomitant with their routine monthly blood transfusion for six months. After six months mean values for ferritin, subcutaneous Deferoxamine were compared with baseline values. Collected data were analyzed using t-test and paired t-test by SPSS, version 18.P<0.05 was considered as significant.Results: Compared with baseline, the subcutaneous Deferoxamine rate and ferritin level have been decreased significantly after intervention.Conclusions: Intravenous Deferoxamine concomitant use with routine monthly blood transfusion in thalassemia major patients can lead to decreasing of ferritin level. With this method, patient care could be improved, health care costs and complications of treatment effectively reduced.

scholarly journals Reticulocyte Hemoglobin Content as a Best Indicator of Iron Deficiency in Female Patients with Diffuse Non-Scarring Hair Loss

2021 ◽  
Vol 14 (3) ◽  
pp. 1359-1362
Author(s):  
Zahraa Jasim ◽  
Hayder Aledan
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Hair Loss ◽  
Laboratory Parameter ◽  
Hemoglobin Content ◽  
Cross Sectional ◽  
Deficiency State ◽  
Female Patients ◽  
Reticulocyte Hemoglobin Content ◽  
Low Serum

Background and objective: Iron deficiency is a well-documented cause of diffuse non-scarring hair loss. We aimed to find the best representative laboratory parameter for iron deficiency. Methods:This was a cross-sectional observational study conducted on 51 female patients with diffuse non-scarring hair loss and iron deficiency state. Iron deficiency was diagnosed as serum ferritin below 30 ng/ml, TSAT below 20% or CHr below 29 pg. Results: Among 51 female patients with diffuse non-scarring hair loss with laboratory proven iron deficiency; low CHrwas reported in 50 (98%) patients, low TSAT was reported in 43 (84.3%) patients, low serum ferritin was reported in 28 (55%). Conclusion:The reticulocyte hemoglobin content (CHr) shows the highest frequency of iron deficiency in patients with diffuse hair loss and iron deficiency state.

scholarly journals Do Laboratory Biomarkers Predict Survival in Severe COVID-19? A Cross-sectional Study

2020 ◽  
Author(s):  
Sher Bahadur ◽  
Fawad Rahim ◽  
Said Amin ◽  
Mohammad Noor ◽  
Afsheen Mahmood ◽  
...  
Keyword(s):  
Serum Ferritin ◽  
Lymphocyte Count ◽  
Ferritin Level ◽  
Cross Sectional Study ◽  
Significant Rise ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Survival Status ◽  
D Dimer

Abstract BackgroundAvailable research compared serum biomarkers such as lymphocyte count, C-reactive protein, ferritin, Lactate Dehydrogenase and D-dimers to predict survival in patients with mild, moderate and severe COVID-19. This study aims to compare these biomarkers among survivors and non-survivors of severe COVID-19. MethodsThis was a cross-sectional study based on patient’s data retrieved from Hospital Information System. Sixty-nine patients for whom a record of the biomarkers and survival status was available, were included in the study. For every patient, baseline and peak values were selected for CRP level, serum ferritin level, serum LDH level and serum D-Dimer level. Similarly, baseline and trough levels were selected for lymphocytes. Data were analyzed using SPSS version 21. Mean and standard deviation was used to compare the biomarkers with paired t-test. P value less than 0.05 was taken as significant. ResultsThe mean age of the study population was 55.5±9.1 years and 72.5% were male. Among survivors, the increase in CRP level was not significant (from 15.80±9.8 mg/dl to 17.87 ±8.4 mg/dl, p=0.45) while among the non-survivor, the increase in CRP level was significant (from 16.68± 10.90 mg/dl to 20.77±12.69 mg/dl, p=0.04). There was no significant rise in serum LDH levels in survivors (from 829.59±499 U/L to 1018.6±468 U/L, p=0.20) while there was a statistically significant increase in serum LDH level in non-survivors (from 816.2±443.08 U/L to 1056.61±480.54 U/L, p=0.003). Lymphocyte count decreased significantly in both survivors (p=0.001) and non-survivors (p=0.001). There was no statistically significant elevation in serum ferritin among the survivors and non-survivors (p > 0.05). The D-Dimer level increased significantly in both survivors (p=0.01) and non-survivors (p=0.001).Conclusions In severe COVID-19 patients, serum CRP and LDH can be used for risk stratification and predicting survival. Lymphopenia, increase in serum ferritin and D-dimers may not predict survival.Trial Registration Not applicable

Frequency of Different Pattern of Hair Loss in Pakistani Men Using BASP Classification

2021 ◽  
Vol 15 (5) ◽  
pp. 1187-1189
Author(s):  
S. Nasreen ◽  
T. Malik ◽  
H. S. Memon ◽  
M. Izhar ◽  
S. M. S. Shah ◽  
...  
Keyword(s):  
Hair Loss ◽  
Cross Sectional Study ◽  
Androgenic Alopecia ◽  
Cross Sectional ◽  
Treatment Plans ◽  
Suitable Treatment ◽  
Surgical Treatments ◽  
Study Setting ◽  
Written Informed Consent ◽  
Male Pattern

Objective: To determine the frequency of different hair loss using BASP classification in Pakistani men. Study Design: Cross-Sectional Study. Setting: Study was conducted at Department of Dermatology, Abbasi Shaheed Hospital, Karachi. Duration: Six months starting 6th August 2019 till 5th January 2020 Material and Methods: Total 157 diagnosed patients with hair loss who met the diagnostic criteria were included. Brief history was taken and demographic information was recorded after taking written informed consent. Male pattern of hair loss (MPHL) was checked and categorized using BASP classification. Data was analyzed by SPSS 24.0. Results: In this study out of 157 patients, mean and standard deviation of age and duration of hair loss were 33.14±12.49 years and 1.89± 0.44 years, respectively. The Pattern of hair loss distribution showed that 34 (21.7%) were L type, 66 (42%) were M type, 35 (22.3%) were C type, and 22 (14%) were U type patterned hair loss. Conclusion: Assessment of male pattern hair loss using BASP classification found that M type hair loss was more prevalent. Currently, there are effective medical and surgical treatments available for men. However, the knowledge of pattern of hair loss in our population would help in choosing suitable treatment plans. Keywords: Male Pattern hair loss, Androgenic alopecia and BASP classification

scholarly journals The Association Between Serum Uric Acid and the Cardiometabolic Phenotype Among Healthcare Workers in Azar Cohort Study

2021 ◽  
Author(s):  
Mohammad hossein Somi ◽  
Negin Frounchi ◽  
Alireza Ostadrahimi ◽  
Seyed Sina Zakavi ◽  
Neda Gilani ◽  
...  
Keyword(s):  
Uric Acid ◽  
Cohort Study ◽  
Serum Uric Acid ◽  
Healthcare Workers ◽  
Liver Enzymes ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Mean Values ◽  
Metabolically Healthy

Abstract Background: As of now, it is unknown whether hyperuricemia can be considered as an independent risk factor or just as a marker to represent the correlation between uric acid and other metabolic syndrome (MetS) risk factors. To the best of the authors’ knowledge, no other work has been reported to study this relationship between serum uric acid (SUA) and cardiometabolic phenotypes. In this work, we intend to study the correlation between SUA and the cardiometabolic phenotype among healthcare workers in Azar cohort study. Method: In this cross-sectional study, anthropometric measurements, serum fasting blood sugar (FBS), triglyceride (TG), cholesterol, high lipoprotein density (HDL), liver enzymes, blood urea nitrogen (BUN), SUA, creatinine (Cr), and blood pressures of 1458 healthcare workers were evaluated. MetS was diagnosed based on ATP III. We classified the participants into four cardiometabolic phenotypes, i.e., metabolically-healthy lean (MHL), metabolically-unhealthy lean (MUHL), metabolically-healthy obese (MHO), and metabolically-unhealthy obese (MUHO).Results: MHL (32.6%) and MHO (66%) have the highest prevalence rate in the first and second SUA tertiles, respectively, which are statistically significant (P-value ≤0.001). We observed an ascending trend in the mean values of WC, TG, cholesterol, low HDL, FBS, BUN, Cr, SBP, DBP, BMI, and liver enzymes from the first SUA tertile to the third SUA tertile (P-value <0.05). Compared to the lowest SUA tertile, the odds of MHO and MUHO increased by 2.29 (95% CI 1.46-3.59) and 5.38 (95%CI 3.45-9.39), respectively. In contrast, no similar trend was observed regarding the association between MUHL and the SUA tertile.Conclusion: We proposed the use of the easily-measured SUA level as a marker for early diagnosis of at-risk MUHL and MHO individuals to administer proper interventions. Further prospective works are needed to identify the effects of SUA on the progression of MetS in various body size subgroups.

scholarly journals SMOKELESS TOBACCO;

2017 ◽  
Vol 24 (09) ◽  
pp. 1310-1315
Author(s):  
Imran Ali Shaikh ◽  
Naila Masood ◽  
Fouzia Aijaz Sheikh ◽  
Talha Shaikh
Keyword(s):  
Vitamin B12 ◽  
Serum Ferritin ◽  
Smokeless Tobacco ◽  
Negative Impact ◽  
Cross Sectional Study ◽  
P Value ◽  
Betel Nut ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein

Objectives: To know the serum ferritin and vitamin B12 levels in relation to Creactive protein in individuals using smokeless tobacco in Hyderabad, sindh, Pakistan. StudyDesign: Cross sectional study. Place of Study: Private clinics of consultants of Hyderabad,Sindh, Pakistan. Duration of Study: January 2016 to February 2017. Methodology: Onehundred eighty three individuals were selected from different clinics of physicians, dentalsurgeons of sadder Hyderabad sindh Pakistan by judgmental sampling. Patients were youngsubjects, mean age was 21.4±7.4 years, mean BMI was 22.1±3.8 and mean duration ofchewing tobacco was 2±1.5 years. All types and forms of gutaka, manpuri and flavored betelnut were included like bombart, zafri and panparag. The dose was 30-100grams once or twotimes. SPSS 16 was used as statical software and Chai square test was used to calculatep value. P value was taken <0.05 statically significant. Results: Frequency of use of gutkawas 32%, Betel nut 38% and 29% had habit of chewing manpuri. Serum ferritin was low andc reactive protein was high, p value was <0.05 in gutaka and manpuri users. Vitamin B12was reduced significantly in gutaka user p value was <0.05. In betel nut chewers significantfinding was only high C reactive protein, p value <0.04. Conclusion: Smokeless tobacco hassignificant negative impact on serum ferritin and vitamin B12 levels. These chewing agents alsoincreased inflammatory markers like c reactive protein.

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