scholarly journals Covid 19 induced destructive impact on a leprosy patient

2021 ◽  
Vol 7 (3) ◽  
pp. 275-277
Author(s):  
Geetha K
Keyword(s):  
Chronic Disease ◽  
Early Diagnosis ◽  
Chronic Diseases ◽  
Erythema Nodosum ◽  
Health Impacts ◽  
Diagnostic Features ◽  
Prompt Treatment ◽  
The Face ◽  
History Of ◽  
Hemorrhagic Bullae

COVID-19 pandemic has caused marked economic, social, and health impacts. People affected by leprosy have additionally been hit via way of means by the pandemic. Many patients have missed their monthly medications. Here is a report of one such case who presented with vasculonecrotic erythema nodosum due to discontinuation of MB MDT therapy. A 26-year-old man affected with leprosy presented to our OPD with a 2- month history of fever, hemorrhagic blisters and ulcers over extremities. On examination, purpuric plaques, hemorrhagic bullae and necrotic ulcers were found on the face and extremities along with erythematous edematous lesions on the trunk. The diagnosis of vasculonecrotic erythema nodosum was made with the characteristic clinical and diagnostic features.Leprosy is a chronic disease with various atypical, rare and unrecognizable manifestations. Early diagnosis and prompt treatment are needed to reduce morbidity and mortality. In this Covid situation, special attention should be paid to chronic diseases such as leprosy by giving appropriate guidelines on how to treat them.

scholarly journals A case of concomitant subcorneal pustular dermatosis and erythema nodosum leprosum in borderline lepromatous leprosy-relapses

2017 ◽  
Vol 4 (4) ◽  
pp. 6
Author(s):  
Hendra Gunawan ◽  
Nina Roslina ◽  
Oki Suwarsa
Keyword(s):  
Erythema Nodosum ◽  
Histopathological Examination ◽  
Lepromatous Leprosy ◽  
Erythema Nodosum Leprosum ◽  
Subcorneal Pustular Dermatosis ◽  
Morphological Index ◽  
The Face ◽  
History Of ◽  
Chronic Course ◽  
Bacterial Index

Subcorneal pustular dermatosis (SPD) is a rare, chronic, and recurrent pustular eruption characterized histopathologically by subcorneal pustules that contain neutrophils. SPD has been clearly reported conjunction with other diseases. Leprosy reactions are acute inflammatory process that immunologically driven on the chronic course of leprosy. Erythema nodosum leprosum (ENL) is a type II of leprosy reaction putatively can initiate SPD lesions. We report one case of concomitant SPD and ENL in borderline lepromatous leprosy-relapses. A 41-year-old man with the history of using multidrug therapy-multibacillary for leprosy presented with painful erythematous nodules on the trunk and extremities, accompanied by pustules on erythematous base on the face, arms, buttocks, and legs. There were thickening of both ulnar nerves with gloves and stocking hypesthesia. The bacterial index was 3+ and morphological index was 20\%. Histopathological examination on the pustule revealed subcorneal pustules with exocytosis of neutrophils which supported the diagnosis of SPD. A possible immunologic mechanism has been suggested in the induction of the occurence both SPD and ENL.

scholarly journals P114 A screening tool for the early diagnosis of extraintestinal manifestations in inflammatory bowel disease: the EMAIL questionnaire

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S192-S193
Author(s):  
A Busacca ◽  
G Ingrassia Strano ◽  
E Giuffrida ◽  
L Guida ◽  
B Scrivo ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Early Diagnosis ◽  
Bowel Disease ◽  
Multidisciplinary Approach ◽  
Screening Tool ◽  
Erythema Nodosum ◽  
Demographic Data ◽  
Extraintestinal Manifestations ◽  
History Of ◽  
Inflammatory Bowel

Abstract Background Data on prevalence of extraintestinal manifestations (EIMs) in inflammatory bowel disease (IBD) range from 6% up to 47%. Recently, several red flags and questionnaires have been proposed for early diagnosis of articular manifestations. Our aim was to analyse the prevalence of EIMs in a single-centre prospective cohort, using a comprehensive questionnaire developed by our group to detect all EIMs (EMAIL questionnaire). Methods Patients with IBD attending our Clinic from November 2017 to January 2019 were interviewed using a two-part questionnaire, the first part for clinical-demographic data and the second part for EIMs. Patients positive to screening were referred for multidisciplinary approach. Results Two hundred and six IBD patients were interviewed, 114 (55.3%) Crohn’s disease (CD) and 92 (44.7%) ulcerative colitis (UC), 52.4% male, mean age 46.7 years (SD ± 15,2). Sixty (53%) CD patients and 48 (52%) UC patients, in total 108, had history of at least one EIM. Articular EIMs were found in 49 patients (24%); peripheral arthritis was found in 14% (29/206), axial arthritis in 9.7% (20 patients): seven patients (3.4%) had ankylosing spondylitis, 13 (6.3%) sacroiliitis. Cutaneous EIMs were detected in 39 patients (19%), erythema nodosum in 15 patients (7.3%), pyoderma gangrenosum in 9 (4.4%), psoriasis in 15 (7.3%) and folliculitis in 7 (3.4%). Ocular EIMs were observed in 35 patients (17%): uveitis in 7 patients (3.4%), conjunctivitis in 8 (3.9%), optic neuritis in 2, glaucoma in 2 patients, cataract in 13 (6,3%), dry eye in 4 (1.9%), central serous chorioretinopathy in 1. Hepatobiliary EIMs were observed in 31 patients (15%): 26 steatosis (12.6%), 5 (2.4%) primary sclerosing cholangitis. Four (2%) patients had DVT. Articular EIMs were more frequent in CD patients (p = 0.001). Skin manifestations were more frequent in female (p = 0.002) in CD (p = 0,032) and related with IBD activity (<0.001). Hepatobiliary manifestations were more frequent in male (p = 0,017) and in UC (p = 0,044). There was a significant correlation between DVT and IBD activity (p = 0,016). Conclusion The questionnaire developed by our group proved to be a sensitive screening tool. Articular and cutaneous EIMs are more frequent in CD, hepatobiliary EIMs are more frequent in UC. A gender difference has been found since cutaneous EIMs are more frequent in females, hepatobiliary more in males. Cutaneous EIMs and DVT are related with IBD activity.

scholarly journals A Homeopathic View of the Influence of Chronic Diseases in the Manifestation of COVID-19

Homeopathy ◽  
2021 ◽  
Vol 110 (01) ◽  
pp. 067-069
Author(s):  
Fernanda Maria Simões da Costa Fujino ◽  
Ana Amélia Campos Claro Olandim ◽  
Vagner Doja Barnabé ◽  
Jennifer Anne Coggan ◽  
Nilson Roberti Benites
Keyword(s):  
Chronic Disease ◽  
Health Status ◽  
Chronic Diseases ◽  
Pulmonary Infection ◽  
Severe Form ◽  
Epidemic Disease ◽  
Chronic Disease Patients ◽  
The Face ◽  
The Individual ◽  
The Relationship

AbstractCOVID-19 (coronavirus disease 2019) may present variable symptoms among infected individuals, with chronic disease patients appearing as the group most susceptible to present severe pulmonary infection, while having a higher risk of developing complications from the disease. This study demonstrates the relationship between the manifestation of COVID-19 and the presence of chronic miasmatic disease, based on the works of Samuel Hahnemann. The reaction of the individual who previously presented chronic miasmatic disease, when in contact with the stimulus of the epidemic disease, depends on the type of response that the organism was generating in the face of the pre-existing situation: if it is an intense reaction and greater than that which the stimulus of COVID-19 can generate, this individual will not develop the severe form of the epidemic disease; if the reaction is less than that generated by COVID-19, more intense symptoms may appear. Understanding that the presence of a chronic miasmatic disease interferes with the manifestation of COVID-19, which may have repercussions on other organs, can change how one must act on the treatment, as this can alter the individual's health status.

scholarly journals Multimorbidity, polypharmacy and primary prevention in community-dwelling adults in Quebec: a cross-sectional study

2019 ◽  
Vol 36 (6) ◽  
pp. 706-712 ◽  
Author(s):  
Tu N Nguyen ◽  
Patrice Ngangue ◽  
Jeannie Haggerty ◽  
Tarek Bouhali ◽  
Martin Fortin
Keyword(s):  
Chronic Disease ◽  
Primary Prevention ◽  
Chronic Diseases ◽  
Strong Association ◽  
Renin Angiotensin System ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Concurrent Use ◽  
History Of

Abstract Background Polypharmacy carries the risk of adverse events, especially in people with multimorbidity. Objective To investigate the prevalence of polypharmacy in community-dwelling adults, the association of multimorbidity with polypharmacy and the use of medications for primary prevention. Methods Cross-sectional analysis of the follow-up data from the Program of Research on the Evolution of a Cohort Investigating Health System Effects (PRECISE) in Quebec, Canada. Multimorbidity was defined as the presence of three or more chronic diseases and polypharmacy as self-reported concurrent use of five or more medications. Primary prevention was conceptualized as the use of statin or low-dose antiplatelets without a reported diagnostic of cardiovascular disease. Results Mean age 56.7 ± 11.6, 62.5% female, 30.3% had multimorbidity, 31.9% had polypharmacy (n = 971). The most common drugs used were statins, renin–angiotensin system inhibitors and psychotropics. Compared to participants without any chronic disease, the adjusted odds ratios (ORs) for having polypharmacy were 2.78 [95% confidence interval (CI): 1.23–6.28] in those with one chronic disease, 8.88 (95% CI: 4.06–19.20) in those with two chronic diseases and 25.31 (95% CI: 11.77–54.41) in those with three or more chronic diseases, P < 0.001. In participants without history of cardiovascular diseases, 16.2% were using antiplatelets and 28.5% were using statins. Multimorbidity was associated with increased likelihood of using antiplatelets (adjusted OR: 2.98, 95% CI: 1.98–4.48, P < 0.001) and statins (adjusted OR: 3.76, 95% CI: 2.63–5.37, P < 0.001) for primary prevention. Conclusion There was a high prevalence of polypharmacy in community-dwelling adults in Quebec and a strong association with multimorbidity. The use of medications for primary prevention may contribute to polypharmacy and raise questions about safety.

scholarly journals Associations between Neighborhood Walkability, Physical Activity, and Chronic Disease in Nova Scotian Adults: An Atlantic PATH Cohort Study

2020 ◽  
Vol 17 (22) ◽  
pp. 8643
Author(s):  
Melanie R. Keats ◽  
Yunsong Cui ◽  
Vanessa DeClercq ◽  
Scott A. Grandy ◽  
Ellen Sweeney ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Chronic Disease ◽  
Chronic Diseases ◽  
Disease Incidence ◽  
Chronic Respiratory Disease ◽  
Cross Sectional ◽  
Neighborhood Walkability ◽  
History Of ◽  
Using Data

Background: While neighborhood walkability has been shown to positively influence health behaviors, less is known about its impact on chronic disease. Our aim was to examine the association between walkability and self-reported physical activity in relation to chronic health conditions in an Atlantic Canadian population. Methods: Using data from the Atlantic Partnership for Tomorrow’s Health, a prospective cohort study, we employed both a cross-sectional and a prospective analytical approach to investigate associations of walkability and physical activity with five prevalent chronic diseases and multimorbidity. Results: The cross-sectional data show that participants with the lowest neighborhood walkability were more likely to have reported a pre-existing history of cancer and depression and least likely to report chronic respiratory conditions. Participants with low physical activity were more likely to have a pre-existing history of diabetes, chronic respiratory disease, and multimorbidity. Follow-up analyses showed no significant associations between walkability and chronic disease incidence. Low levels of physical activity were significantly associated with diabetes, cancer and multimorbidity. Conclusions: Our data provides evidence for the health protective benefits of higher levels of physical activity, and a reduction in prevalence of some chronic diseases in more walkable communities.

Detection of Chronic Disease in Primary Care Using Artificial Intelligence Techniques

2020 ◽  
pp. 195-219
Author(s):  
Hakan Gulmez
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Primary Care ◽  
Chronic Disease ◽  
Early Detection ◽  
Early Diagnosis ◽  
Chronic Diseases ◽  
Global Burden ◽  
Access Data ◽  
Intelligence Technique

Chronic diseases are the leading causes of death and disability worldwide. By 2020, it is expected to increase to 73% of all deaths and 60% of global burden of disease associated with chronic diseases. For all these reasons, early diagnosis and treatment of chronic diseases is very important. Machine learning is an application of artificial intelligence that provides systems the ability to automatically learn and improve from experience without being explicitly programmed. Machine learning is the development of computer programs that can access data and use it to learn for themselves. The learning process starts by searching for patterns in the examples, experiences, or observations. It will make faster and better decisions in the future based on all these. The primary purpose in machine learning is to allow computers to learn automatically without human help and affect. Considering all the reasons above, this chapter finds the most appropriate artificial intelligence technique for the early detection of chronic diseases.

scholarly journals Chorea as the first presenting sign of rheumatic fever in a 12-year-old female child

2020 ◽  
Vol 7 (6) ◽  
pp. 1444
Author(s):  
Mitul N. Kasundra
Keyword(s):  
Early Diagnosis ◽  
Rheumatic Fever ◽  
Children And Adolescents ◽  
Movement Disorder ◽  
Clinical Sign ◽  
Female Child ◽  
Treated Group ◽  
Prompt Treatment ◽  
History Of ◽  
Group A

Rheumatic chorea (RC*) is a movement disorder seen in young children and adolescents with a recent history of incompletely treated group A beta-hemolytic streptococcal (GABHS) pharyngitis. Although, it rarely presents as the first manifestation of the rheumatic fever, physicians should be aware of the disease, so that early diagnosis and prompt treatment may lead to elimination of the pathogen and prevent further disease progression. We present a case of a 12-year-old female child who presented with only RC as the first clinical sign.

Luxury Communist Jesus

2016 ◽  
Vol 7 (3) ◽  
pp. 245-255 ◽  
Author(s):  
Michael J. Sandford
Keyword(s):  
Work Ethic ◽  
Protestant Work Ethic ◽  
The Face ◽  
History Of ◽  
The Protestant Work Ethic

This article begins by outlining contemporary anti-work politics, which form the basis of Sandford’s reading. After providing a brief history of anti-work politics, Sandford examines recent scholarly treatments of Jesus’ relationship to work. An examination of a number of texts across the gospel traditions leads Sandford to argue that Jesus can be read as a ‘luxury communist’ whose behaviour flies in the face of the Protestant work ethic. Ultimately, Sandford foregrounds those texts in which Jesus discourages his followers from working, and undermines work as an ‘end in itself’, contextualising these statements in relation to other gospel texts about asceticism and the redistribution of wealth.

More Eggs, Less Sugar: A Sneak Peek into the Latest Dietary Guidelines for Americans

2018 ◽  
Vol 7 (1) ◽  
pp. 22-24
Author(s):  
Darlene Zimmerman
Keyword(s):  
Cardiovascular Disease ◽  
Chronic Disease ◽  
Chronic Diseases ◽  
Dietary Guidelines ◽  
Healthy Diet ◽  
Dietary Guidelines For Americans

ABSTRACT The 2015 – 2020 Dietary Guidelines for Americans provides guidance for choosing a healthy diet. There is a focus on preventing and alleviating the effects of diet-related chronic diseases. These include obesity, diabetes, cardiovascular disease, and stroke, among others. This article briefly reviews the primary guideline items that can be used to teach patients with respect to improving their diet. Clinical exercise physiologists who work with patients with chronic disease can use these guidelines for general discussions regarding a heart-healthy diet.

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