scholarly journals Chorea as the first presenting sign of rheumatic fever in a 12-year-old female child

2020 ◽  
Vol 7 (6) ◽  
pp. 1444
Author(s):  
Mitul N. Kasundra

Rheumatic chorea (RC*) is a movement disorder seen in young children and adolescents with a recent history of incompletely treated group A beta-hemolytic streptococcal (GABHS) pharyngitis. Although, it rarely presents as the first manifestation of the rheumatic fever, physicians should be aware of the disease, so that early diagnosis and prompt treatment may lead to elimination of the pathogen and prevent further disease progression. We present a case of a 12-year-old female child who presented with only RC as the first clinical sign.

PEDIATRICS ◽  
1948 ◽  
Vol 2 (4) ◽  
pp. 410-414
Author(s):  
PAUL F. DEGARA

Agglutinative antibodies for three different strains Str. hemolyticus, beta, group A, were studied in 497 sera from 372 children. A high titer was found in approximately 9% of well children. There was no significant difference between rheumatic and non-rheumatic subjects in the incidence of high agglutinin titers for Str. hemolyticus. Following infections, presumably streptococcal in origin, approximately 46% of the children examined had high agglutinin titers for Str. hemolyticus. In active rheumatic fever, agglutinins were present in high titers in nine out of 11 patients who had experienced an antecedent illness, presumably streptococcal in origin. Of 23 patients with no history of such an infection, only three had streptococcal agglutinins.


2021 ◽  
Vol 7 (3) ◽  
pp. 275-277
Author(s):  
Geetha K

COVID-19 pandemic has caused marked economic, social, and health impacts. People affected by leprosy have additionally been hit via way of means by the pandemic. Many patients have missed their monthly medications. Here is a report of one such case who presented with vasculonecrotic erythema nodosum due to discontinuation of MB MDT therapy. A 26-year-old man affected with leprosy presented to our OPD with a 2- month history of fever, hemorrhagic blisters and ulcers over extremities. On examination, purpuric plaques, hemorrhagic bullae and necrotic ulcers were found on the face and extremities along with erythematous edematous lesions on the trunk. The diagnosis of vasculonecrotic erythema nodosum was made with the characteristic clinical and diagnostic features.Leprosy is a chronic disease with various atypical, rare and unrecognizable manifestations. Early diagnosis and prompt treatment are needed to reduce morbidity and mortality. In this Covid situation, special attention should be paid to chronic diseases such as leprosy by giving appropriate guidelines on how to treat them.


2019 ◽  
Vol 3 (2) ◽  
pp. 13
Author(s):  
Diana Victoria Moreira Vera ◽  
David Ramón Cedeño Vélez ◽  
Egny María Mendoza Guillem

  La fiebre reumática es la secuela más común por amigdalitis debida al estreptococo β-hemolítico del grupo A, siendo la causa más frecuente de valvulopatía adquirida en niños. Se presenta el caso de una niña de 10 años de edad que acudió a emergencias debido a artralgia en rodillas, piernas y tobillos, de ocho días de evolución alternando su intensidad 48 horas en cada articulación y fiebre de 39ºC. Antecedentes de faringoamigdalitis a repetición desde los dos años con sugerencia de amigdalectomía. Se observaron valores de antiestreptolisina positivos. Se encontró artritis como criterio mayor y la fiebre junto con los valores de la antiestreptolisina como criterios menores, además de los antecedentes de amigdalitis a repetición. Su relevancia recae en el abordaje variado que recibió la paciente y la duda diagnóstica de la enfermedad.   Palabras clave: Fiebre reumática, poliartritis, faringitis, criterios de Jones.   Abstract Rheumatic fever is the most common sequel due to tonsillitis caused by the group A β-hemolytic streptococci, being the most frequent reason of acquired valvulopathy in children. The case of a 10-year-old girl who went to the emergency room due to arthralgia in the knees, legs and ankles of eight days of evolution - alternating its intensity 48 hours in each joint - and fever of 39 ºC is presented. History of pharyngotonsillitis repeated since two years-old with suggestion of tonsillectomy. Anti streptolysin values were positive. Arthritis was found as major criterion and fever along with anti streptolysin values as minor criteria, in addition to the history of recurrent tonsillitis. Its relevance lies in the varied approach that the patient received and the diagnostic doubt of the disease.   Keywords: Rheumatic fever, polyarthritis, pharyngitis, Jones criteria.


2018 ◽  
Vol 52 (1-4) ◽  
pp. 22-30
Author(s):  
A K Paul ◽  
S M T Rahman

Hormonal treatment of cows at the coastal region of Barisal district of Bangladesh was performed to assess the improvement of pregnancy rate. A total of 100 cows and heifers with irregular history of cyclicity were selected randomly and divided into five treatment groups. The groups were A (treated with anthelmintic), B (treated with anthelmintic, vitamin ADE and multivitamin powder), C (treated with PGF2α), D (treated with GnRH) and E (treated with GnRH and PGF2α). Each group comprised of 20 animals. The age, breed and parity of experimental cows were considered during treatment. In the study, the cows treated with both GnRH and PGF2α (group E) showed significantly (p<0.05) higher estrus (80%) and pregnancy rate (60%) than that of group A, B, C and D. The overall estrus rates of local and crossbred cows were 64% and 70%, respectively and the pregnancy rates were 40 and 52%, respectively. The crossbred cows responded significantly (p<0.05) to hormonal treatment than that of local cows. Parity-2 cows showed higher estrus sign than that of other parities. However, the pregnancy rates were higher significantly (p<0.05) in parity-2 and parity ≥4 cows than that of parity-0, parity-1 and parity-3 cows. The pregnancy rate was also found higher in case of 4 to <5 years old cows than that of 2 to <3, 3 to <4, 5 to <6, and ≥6 years old. It may conclude that the hormonal regimen increases the pregnancy rate as well as decreases the undesired waiting of estrus and conception. Further study with more sample size will reveal the more effective treatment for cows at the coastal areas of Bangladesh.


2018 ◽  
Vol 52 (1-4) ◽  
pp. 22-30
Author(s):  
A K Paul ◽  
S M T Rahman

Hormonal treatment of cows at the coastal region of Barisal district of Bangladesh was performed to assess the improvement of pregnancy rate. A total of 100 cows and heifers with irregular history of cyclicity were selected randomly and divided into five treatment groups. The groups were A (treated with anthelmintic), B (treated with anthelmintic, vitamin ADE and multivitamin powder), C (treated with PGF2α), D (treated with GnRH) and E (treated with GnRH and PGF2α). Each group comprised of 20 animals. The age, breed and parity of experimental cows were considered during treatment. In the study, the cows treated with both GnRH and PGF2α (group E) showed significantly (p<0.05) higher estrus (80%) and pregnancy rate (60%) than that of group A, B, C and D. The overall estrus rates of local and crossbred cows were 64% and 70%, respectively and the pregnancy rates were 40 and 52%, respectively. The crossbred cows responded significantly (p<0.05) to hormonal treatment than that of local cows. Parity-2 cows showed higher estrus sign than that of other parities. However, the pregnancy rates were higher significantly (p<0.05) in parity-2 and parity ≥4 cows than that of parity-0, parity-1 and parity-3 cows. The pregnancy rate was also found higher in case of 4 to <5 years old cows than that of 2 to <3, 3 to <4, 5 to <6, and ≥6 years old. It may conclude that the hormonal regimen increases the pregnancy rate as well as decreases the undesired waiting of estrus and conception. Further study with more sample size will reveal the more effective treatment for cows at the coastal areas of Bangladesh.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 48-52
Author(s):  
E N Kravchenko ◽  
R A Morgunov

The aim of the study. Assess the importance of pregravid preparation and outcomes of pregnancy and childbirth, depending on the reproductive attitudes of women in the city of Omsk. Materials and methods. The study included 92 women who were divided into groups: group A (n=43) - women whose pregnancy was planned; group B (n=49) - women whose pregnancy occurred accidentally. Each group was divided into subgroups depending on age: from 18 to 30 and from 31 to 49 years. For each patient included in the study, a specially designed map was filled out. These patients were interviewed at the City Clinical Perinatal Center. Results. Comparative analysis revealed the relationship between the reproductive settings of women of childbearing age and the peculiarity of the course of pregnancy and childbirth in these patients. Summary. The majority of women of fertile age are married: in subgroup AA - 25 (96.2%), AB - 13 (76.5%), BA - 25 (92.6%), BB - 20 (91.0%). The predominant number of women of fertile age have one or more abortions: in subgroup AA - 12 (46.2%), AB - 6 (35.3%), in subgroups of comparison BA - 8 (29.6%), BB - 6 (27.3%). More than half of the women of fertile age surveyed have a history of untreated cervical pathology (from 40.8% to 64.7%). The course of pregnancy in women planning pregnancy in most cases proceeded without complications: in subgroup AA - 13 (50.0%), AB - 11 (64.7%). The most common cause of complicated pregnancy in women whose pregnancy occurred accidentally is the threat of spontaneous miscarriage: in subgroup BA - 15 (55.6%), BB - 16 (72.7%). The uncomplicated course of labor more often [subgroup AA - 19 (73.0%), AB - 12 (70.6%)] was observed in women whose pregnancy was planned and they were motivated to give birth to a healthy child.


2020 ◽  
Vol 16 ◽  
Author(s):  
Molla Imaduddin Ahmed ◽  
Rosalind V Saunders ◽  
Srini Bandi

: We reviewed the clinical presentation and management of children with Invasive group A streptococcal infections admitted to our tertiary Children’s Hospital in the last eight years. Our study highlighted the varied symptomatology and management practices in children with iGAS and showed that early diagnosis and prompt initiation of appropriate antibiotics for iGAS can help in resolution of symptoms and good outcome.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Charity Wiafe Akenten ◽  
Kennedy Gyau Boahen ◽  
Kwadwo Sarfo Marfo ◽  
Nimako Sarpong ◽  
Denise Dekker ◽  
...  

Abstract Background The increasing incidence of multi-antibiotic-resistant bacterial infections, coupled with the risk of co-infections in malaria-endemic regions, complicates accurate diagnosis and prolongs hospitalization, thereby increasing the total cost of illness. Further, there are challenges in making the correct choice of antibiotic treatment and duration, precipitated by a lack of access to microbial culture facilities in many hospitals in Ghana. The aim of this case report is to highlight the need for blood cultures or alternative rapid tests to be performed routinely in malaria patients, to diagnose co-infections with bacteria, especially when symptoms persist after antimalarial treatment. Case presentation A 6-month old black female child presented to the Agogo Presbyterian Hospital with fever, diarrhea, and a 3-day history of cough. A rapid diagnostic test for malaria and Malaria microscopy was positive for P. falciparum with a parasitemia of 224 parasites/μl. The patient was treated with Intravenous Artesunate, parental antibiotics (cefuroxime and gentamicin) and oral dispersible zinc tablets in addition to intravenous fluids. Blood culture yielded Acinetobacter baumanii, which was resistant to all of the third-generation antibiotics included in the susceptibility test conducted, but sensitive to ciprofloxacin and gentamicin. After augmenting treatment with intravenous ciprofloxacin, all symptoms resolved. Conclusion Even though this study cannot confirm whether the bacterial infection was nosocomial or otherwise, the case highlights the necessity to test malaria patients for possible co-infections, especially when fever persists after parasites have been cleared from the bloodstream. Bacterial blood cultures and antimicrobial susceptibility testing should be routinely performed to guide treatment options for febril illnesses in Ghana in order to reduce inappropriate use of broad-spectrum antibiotics and limit the development of antimicrobial resistance.


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