Study of occurrence of HBeAg among Hepatitis- B surface antigen positive cases

Hepatitis is a universal concept that mean inflammation of the liver and infection with 1 of the 5 viruses called hepatitis A, B, C, D and E viruses is the almost common cause. The 5 viral cause’s hepatitis-B infection is the worldly almost common hepatic infection, which is cause by hepatitis-B (HBV). HBV is a DNA virus. It is 42–47 nm in diameter and enters the liver through with blood stream. HBV is highly contagious and is 60–100 times more than HIV. It is transmissible throughly with blood cell and all body fluid or mucosa membranous. It is transmitted almost normally by unsafe physical sexual contact, contaminated blood transfusions and unsterilized use needles from mother to baby, close household touch and in the midst of children in early childhood. Study of occurrence of HBeAg among Hepatitis- B surface antigen positive cases; 1. Identification of Hepatitis B Surface Antigen positive cases; 2. Occurrence of HBeAg among Hepatitis- B surface antigen positive cases. 5ml blood was collected from anterior cubital vein by Venipuncture from recruited patient. Samples were collected after proper consent and aseptic precautions. Then every blood sample was transfer overhead a tagged tube plane vial The study was conducted in Department of Microbiology, Teerthanker Mahaveer Hospital. Blood sample from 106 patients including both male and female were collected from various department of the Hospital for the analysis purpose. Out of them, 38 (36%) cases were HBeAg positive and 68 (64%) cases were HBeAg negative: The result of our study put up valuable information and connection in HBeAg positive cases. In this little sample size 106 analysis of the patients at Uttar Pradesh Teerthanker Mahaveer Medical College, the prevalence of HBeAg (positive results) in the department of medical microbiology, while the negative result is 68(64%).Males 29(76%) were more affected by the HBV (HBeAg) infection as compare to Female 9(24%).An important preventive measure is the screening for HBV in blood donors. Hepatitis-B related chronic liver disease and hepatocellular carcinoma are best prevented by universal childhood immunization. In non-infected people, HBV infection can be avoided by HBV vaccination.Injections Sequence 3 at 0, 1 and 6 months. In over 90% of recipients vaccination is successful.

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A Comparative Evaluation for Detection of Hepatitis B Surface Antigen and Anti HCV Antibodies by Rapid Diagnostic Tests and ELISA Method at Govt. Medical College, Dungarpur, India

International Journal of Current Microbiology and Applied Sciences ◽

10.20546/ijcmas.2019.807.218 ◽

2019 ◽

Vol 8 (07) ◽

pp. 1835-1843

Author(s):

Bhupendra Kumar Mandawat ◽

Vipul Mathur

Keyword(s):

Hepatitis B ◽

Surface Antigen ◽

Diagnostic Tests ◽

Comparative Evaluation ◽

Hepatitis B Surface Antigen ◽

Rapid Diagnostic Tests ◽

Elisa Method ◽

Medical College

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Assessing the Prevalence of Hepatitis B Surface Antigen in the Northern Brong Ahafo Region of Ghana: Locus of Intervention Model

Medical & Clinical Research ◽

10.33140/mcr.03.04.03 ◽

2018 ◽

Vol 3 (4) ◽

Keyword(s):

Hepatitis B ◽

Blood Sample ◽

Surface Antigen ◽

Screening Program ◽

Hepatitis B Surface Antigen ◽

University Hospital ◽

Sample Population ◽

Finger Prick ◽

Brong Ahafo Region ◽

Brong Ahafo

Background: Scarcely was found any data on the prevalence of hepatitis B surface antigen in the Brong-Ahafo Region of Ghana. This study was conducted in six traditional areas in the Northern Part of Brong-Ahafo Region, to ascertain prevalence of hepatitis B surface antigen among the respondents to recommend intervention strategies for control and prevention. Method of data gathering: The data was obtained from the department of Preventive Healthcare and Lifestyle Medicine at Valley View University Hospital, Techiman Campus. 444 respondents were assessed on the presence of hepatitis B surface antigen by community healthy health screening program. They were adults between 18 and 59 years old who were from Techiman, Nkoranza, Atebubu, Kwamedanso, Yeji and Kajiji traditional areas, all in the Brong-Ahafo Region, Ghana. The blood sample was collected by a finger prick. Sample population: There were 444 respondents: 198 (44.5%) males and 246 (55.4%) females. Study design: The study is basically cross seasonal. Limitations: This paper is to assess the prevalence of hepatitis B surface antigen among the respondents. Also, serum blood sample was not taken but the whole blood from a finger prick. This study is again limited to the causes and spread of hepatitis B surface antigen since such data could be obtained from peer review journals, textbooks, and qualitative, or clinical research. Results: Out of 444 respondents, 415(93.4%) were negative with hepatitis B surface antigen. 19 (4.2%) respondents tested positive. 10 (2.2%) males and 9 (2.0%) females respectively. Cumulatively, 4.2% of the sample populations were positive. Conclusion: education on the awareness, mode of transmission, effects and prevention of hepatitis B surface antigen are timely needed to save several thousand from poorer health outcome and mortalities in the Brong-Ahafo Region of Ghana.

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Reporting hepatitis-B surface antigen-positive pregnant women

PsycEXTRA Dataset ◽

10.1037/e411652008-008 ◽

2005 ◽

Keyword(s):

Hepatitis B ◽

Pregnant Women ◽

Surface Antigen ◽

Hepatitis B Surface Antigen

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Unexpected increase of Hepatitis B Surface Antigen (HBsAg) levels during treatment with nucleos(t)ide analogous 12–24 months before virological breakthrough and resistance

Zeitschrift für Gastroenterologie ◽

10.1055/s-0031-1295950 ◽

2012 ◽

Vol 50 (01) ◽

Author(s):

S Wiegand ◽

J Jaroszewicz ◽

B Zacher ◽

K Wursthorn ◽

K Deterding ◽

...

Keyword(s):

Hepatitis B ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Virological Breakthrough

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IL10 Promotorpolymorphismen beeinflussen die Hepatitis B Surface Antigen und die Hepatitis A spezifische Immunantwort

Zeitschrift für Gastroenterologie ◽

10.1055/s-0035-1555166 ◽

2015 ◽

Vol 41 (08) ◽

Author(s):

E Reuss ◽

N Evers ◽

N Dietrich ◽

J Vollmar ◽

PM Schneider ◽

...

Keyword(s):

Hepatitis B ◽

Surface Antigen ◽

Hepatitis A ◽

Hepatitis B Surface Antigen

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Effects of Vancomycin on Platelets, Plasma Proteins and Hepatitis B Surface Antigen

Thrombosis and Haemostasis ◽

10.1055/s-0038-1651448 ◽

1975 ◽

Vol 34 (01) ◽

pp. 083-093 ◽

Cited By ~ 2

Author(s):

Barry S Coller ◽

W. B Lundberg ◽

Harvey R Gralnick

Keyword(s):

Hepatitis B ◽

Factor Viii ◽

Surface Antigen ◽

Plasma Proteins ◽

Hepatitis B Surface Antigen ◽

Infusion Site ◽

Vancomycin Therapy ◽

Intravenous Injections ◽

Low Concentrations ◽

High Doses

SummaryThe antibiotic vancomycin shares many similarities with ristocetin, an agent noted for its effects on platelets and plasma fibrinogen. Vancomycin did not aggregate platelets as ristocetin, but platelets were incorporated into precipitates induced by vancomycin. Fibrinogen and factor VIII were precipitated from plasma at low concentrations of vancomycin. The precipitated fibrinogen remained clottable. Hepatitis B surface antigen was selectively precipitated from serum and could be recovered from the precipitate. Rabbits receiving bolus intravenous injections of high doses of vancomycin developed hypofibrinogenemia and thrombocytopenia within minutes and often went on to die. Studies with 125I-vancomycin revealed little stable binding of the antibiotic to platelets or fibrinogen. A relationship is suggested between the potent protein precipitating effects and phlebitis at the infusion site commonly associated with vancomycin therapy.

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SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i8.495 ◽

2019 ◽

Vol 3 (8) ◽

Author(s):

Anusha P ◽

Bankar Nandkishor J ◽

Karan Jain ◽

Ramdas Brahmane ◽

Dhrubha Hari Chandi

Keyword(s):

Hepatitis B ◽

Blood Donors ◽

Hepatitis B Surface Antigen ◽

Tertiary Care ◽

Laboratory Diagnosis ◽

Blood Bank ◽

Care Hospital ◽

Medical College ◽

The World ◽

First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

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