scholarly journals Cutaneous Malakoplakia of perianal skin: Report of a rare lesion at an unusual site

2021 ◽  
Vol 8 (3) ◽  
pp. 422-424
Author(s):  
Swapna Somnath Magdum ◽  
Madhura D Phadke ◽  
Jaydeep N Pol ◽  
Girish A Kadkol

Malakoplakia is a rare chronic granulomatous inflammatory condition, commonly presenting in immunocompromised patients. It most commonly occurs in urinary tract. The cutaneous form is less frequent. Here, we report a case of cutaneous malakoplakia involving perianal skin in an immunocompetent 61-year old female diagnosed on histopathology utilizing special stains. To the best of authors’ knowledge, this is the 8case report of cutaneaous malakoplakia of perianal skin in the English literature and 3in the Indian literature.

Author(s):  
Rui Seixas ◽  
Adelaide Alves ◽  
Aurelia Selaru ◽  
Manuela Vanzeller ◽  
Teresa Shiang ◽  
...  

Raoultella ornithinolytica is a bacterium that belongs to the Enterobacteriaceae family. The most frequently reported infections are gastrointestinal and hepatobiliary. Urinary tract infections are very rarely reported and bloodstream infections are usually reported without an identified source. This bacterium is responsible for an increasing number of infections, especially in immunocompromised patients. The authors describe the first case ever reported of an immunocompromised patient due to non-Hodgkin lymphoma MALT type and corticotherapy, who developed urinary tract infection and subsequently bacteriemia due to this pathogen.


2002 ◽  
Vol 126 (8) ◽  
pp. 975-978 ◽  
Author(s):  
Subodh M. Lele ◽  
Satish Chundru ◽  
Gregory Chaljub ◽  
Patrick Adegboyega ◽  
Abida K. Haque

Abstract Hibernomas are rare neoplasms composed of brown adipose tissue. The behavior of these neoplasms has been described as uniformly benign in humans. The only recurrence cited in the English literature involved a sarcoma with hibernoma-like features, which was reported in abstract form. We present 2 cases of hibernoma, one that continued to grow following partial excision and another at an unusual site (anterior abdominal wall). Both of these tumors overexpressed p53 protein by immunohistochemistry, which was a novel finding. A review of the literature highlights recent advances that may help confirm the diagnosis and explain the biology of these rare tumors.


2020 ◽  
Vol 81 (06) ◽  
pp. 565-570
Author(s):  
Alok Mohan Uppar ◽  
Shilpa Rao ◽  
Chandrajit Prasad ◽  
Arivazhagan Arimappamagan ◽  
Vani Santosh

AbstractGreater superficial petrosal nerve (GSPN) schwannoma is a rare clinical entity. It forms a small subset of the larger group of facial nerve schwannomas. A thorough literature search yielded only 27 such cases reported to date in the English literature. We present one such rare case of GSPN schwannoma and discuss the clinical spectrum and management along with a review of the literature. We demonstrate the surgical steps in an operative video.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Anjali Chaubey

This paperrevisits Sujit Mukherjee’s seminal work Translation as Discovery and Other Essays on Indian Literature in English Translation (1981) to analyze his contribution in foregrounding the translation traditions of India. In the book, he uses the term ‘transcreation’ to refer to translation as a practice in the Indian literary scenario and cites examples from the ancient to modern times, to show how we have perceived and practiced translation. He centers this process in contrast to the western practice of the same, which makes translation a postcolonial exercise. He emphasizes the need to focus on the pragmatic analysis of the process of translation and looking at the ‘Indo-English literature’, as ‘a limb of the body, the purusha, that is Indian literature’ which would help in decolonizing literary studies.


2021 ◽  
Vol 6 (2) ◽  
pp. 103-107
Author(s):  
Zeba Nisar ◽  
Jaydeep N. Pol ◽  
Sachin J Patil ◽  
Rakhi V Jagdale

To study ten cases of toxoplasmic lymphadenitis (TL) in which the diagnosis was made by fine needle aspiration cytology and confirmed by subsequent serology. Retrospective study done over a period of five years. We retrieved ten cases of Toxoplasma lymphadenitis in which fine-needle aspiration cytology (FNAC) of lymph node was done after clinical examination. Serology with electrochemiluminescense was done in all the cases. The cytological features were characterised by microgranulomas, abundance of tingible body macrophages and absence of necrosis. Serologic testing for toxoplasma in all the cases revealed elevated titres. Lymphadenitis due to Toxoplasma infection should be considered in the diagnosis of unexplained lymphadenopathy at all sites, especially the cervical region. Serologic confirmation should be recommended for all suspected cases. FNAC diagnosis can eliminate the need for hospitalization and surgery. To the best of authors’ knowledge, this is 5 case series of cytodiagnosis of TL in the English literature and 2 in the Indian literature. This is the largest case series of cytodiagnosis of TL in the Indian literature and 2 largest in the world literature next to the one done by Haque et al.


2021 ◽  
Vol 8 (3) ◽  
pp. 429-432
Author(s):  
Rakhi V Jagdale ◽  
Jaydeep N Pol

Ewing sarcoma/Primitive Neuroectodermal Tumor (ES/PNET) is a malignant small round blue cell tumor of neuroectodermal origin that affects bones and soft tissue in children and young adults. ES/PNET is very uncommon in parenchymal organs. We report a case of primary adrenal PNET in a young female having pregnancy induced persistent hypertension. She underwent right adrenalectomy for a large adrenal mass. On histopathology, it was typical malignant round cell tumor (MRCT). Immunohistochemistry confirmed the diagnosis of ES/PNET with expression of CD99, FLI-1 and NKX2.2. Until now, only 38 cases of primary adrenal ES/PNET have been reported in the English literature with just 5 cases from India. Adrenal ES/PNET can be mistaken with other MRCTs like Non-Hodgkin lymphoma and neuroblastoma. Since the biology, treatment and prognosis of these tumors is entirely different, we emphasize that pathologists must be aware of this possibility and try to differentiate them using ancillary techniques.


2021 ◽  
pp. 95-100
Author(s):  
Berna Aytaç Vuruşkan ◽  
Ezgi Işıl Turhan ◽  
Hakan Vuruşkan ◽  
İsmet Yavaşcaoğlu

Objective: Nephrogenic adenomas (NA) are benign lesions that may occur in several sites throughout the urinary tract, from the renal pelvis to urethra, and especially in the bladder. They are strongly associated with urinary tract irritation, chronic inflammation, previous urologic surgery, and intravesical instrumentations. Our study aims to evaluate and present the clinicopathologic characteristics and findings of cases that were diagnosed with nephrogenic adenoma accompanied by relevant information from the literature. Material and Methods: Our study includes 30 patients who were pathologically diagnosed with NA from February 2005 to November 2017. Results: Among these patients, 63.3% were males and mean age was 60 years. The most common site of occurrence was the bladder (86.6%), followed by the ureter (6.7%) and the urethra (6.7%). Most patients presented with hematuria (36.7%). History of concurrent bladder cancer was present in 26.7% of patients, but there were no cases of de novo bladder cancer diagnosed after NA. Recurrence of NA after initial resection occurred in only 10% of patients who underwent follow-up cystoscopy. Nephrogenic adenoma is a rare lesion associated with nonspecific symptoms and endoscopic features. Definite diagnosis must be made after histological analysis of resected specimens. Conclusion: Nephrogenic adenoma is a rare lesion associated with nonspecific symptoms and nonspesific endoscopic features. A definite diagnosis must be after histological analysis of resected specimens. Keywords: nephrogenic adenoma, urothelial lesion, bladder, ureter


Author(s):  
William G. Herrington ◽  
Aron Chakera ◽  
Christopher A. O’Callaghan

The urinary tract can become obstructed by various disease processes, including tumours. Obstruction at any level of the urinary tract can impair the free flow of urine and may be partial or complete, and unilateral or bilateral. Bilateral obstruction usually occurs at the level of the bladder or lower. Retroperitoneal fibrosis and extrinsic compression of both ureters by a malignancy are exceptions. Children are affected by congenital vesicoureteric junction obstruction or pelvi-ureteric junction obstruction. Young adults suffer stone disease. The elderly are prone to urothelial cancers, and older men to bladder outflow obstruction. Retroperitoneal fibrosis is an inflammatory condition that typically affects men over 50 years of age. Diagnosis should be confirmed by biopsy to exclude a lymphoma or malignancy.


2021 ◽  
Vol 14 (8) ◽  
pp. e243785
Author(s):  
Soban Ahmad ◽  
Madeleine Cutrone ◽  
Sundus Ikram ◽  
Amman Yousaf

Proteus mirabilis is a gram-negative bacterium frequently considered a pathogen of the urinary tract. Septic discitis and septic pulmonary emboli resulting from P. mirabilis urosepsis is a rare phenomenon. We report a 39-year-old woman who was admitted to our hospital with a complicated urinary tract infection resulting in bacteraemia, septic discitis, paraspinal abscesses and septic emboli. She was treated with a prolonged course of intravenous antibiotics resulting in the clinical resolution of her symptoms. Based on our PubMed search of the English literature, this is only the second reported case of septic discitis caused by P. mirabilis. This paper illustrates that physicians should include septic discitis caused by P. mirabilis as a possible aetiology of low back pain in patients with active or recently treated urinary tract infection. Additionally, this article discusses the pathogenesis and other complications resulting from P. mirabilis bacteraemia.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Heidi Reinhard ◽  
Dipti M. Karamchandani

Colorectal mucosa with Russell bodies is a reactive inflammatory lesion composed of mature plasma cells, known as Mott cells which contain multiple intracytoplasmic eosinophilic globules. To the best of our knowledge, 3 case reports of colorectal Russell body containing lesions have been reported in the English literature (searched from 1980 to date), including just one case report of Colonic Russell body inflammatory polyp. Their importance lies in being aware of this unusual entity, recognizing it as well as the clinical scenario in which this typically arises and differentiating it from its malignant mimics that come in the histologic differential. This review discusses the clinical and endoscopic presentation, histopathologic features, ancillary studies, pathogenesis, differential diagnosis, prognosis, and treatment of this rare lesion.


Sign in / Sign up

Export Citation Format

Share Document