scholarly journals SERUM HOMOCYSTEINE AS A RISK FACTOR IN ISCHAEMIC STROKE- A CROSS-SECTIONAL OBSERVATIONAL STUDY IN A TERTIARY CARE TEACHING HOSPITAL IN NORTHERN KERALA

2017 ◽  
Vol 4 (4) ◽  
pp. 163-167
Author(s):  
Smitha Kalarikkal Satheesan ◽  
Shibu Thadathil Sreedharan ◽  
Parvathi Krishna Warrier
Keyword(s):  
Risk Factor ◽  
Observational Study ◽  
Ischaemic Stroke ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Serum Homocysteine

scholarly journals A Cross-sectional Observational Study to Find out the Pattern of Drug Utilization and Medication Adherence of Anti-Epileptic Drugs (AEDs) among Epileptic Patients at a Tertiary Care Teaching Hospital

2021 ◽  
pp. 62-71
Author(s):  
Sunil Kardani ◽  
Rajesh Hadia ◽  
Jay Patel ◽  
Jeel Patel ◽  
Trupal Rathod ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Observational Study ◽  
Drug Utilization ◽  
Sodium Valproate ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Epileptic Patients

Background: Antiepileptic drugs (AEDs) are the mainstay of the therapy for epilepsy, despite the development in recent years of new therapeutic options, such as brain stimulation or Surgery. Objective: To understand the pattern of drug utilization and medication adherence of anti-epileptic drugs (AEDs) among epileptic patients at a tertiary care teaching hospital. Methodology: A cross-sectional observational study of a total of 120 subjects receiving anti-epileptics was done. All the patients with epilepsy were prescribed with anti-epileptic drug who visited, admitted, or referred to the Department of Neurology. All inpatients and outpatients of epilepsy were screened for the study. Results: A total of 120 patients were included in our study into which (38.33%) were inpatients and (61.67%) were outpatient. The male (56%) patients were more as compared to female (44%) patients. A maximum number of patients were from the age group of 21-40 (41%) year. The majority of the patient were suffered from focal epilepsy (63%), remaining were having a generalized seizure. The highest comorbidities were found to be HTN and diabetes mellitus. Monotherapy was highly prescribed as compare to polytherapy. Among single AED, the maximum prescribed drug was Carbamazepine [30% (N=17)] followed by 25% (N=14) of phenytoin and levetiracetam 21% (N=12). In two AED Combinations, the most prescribed drugs were clobazam + Levetiracetam and Midazolam + phenytoin 12% (N=5) followed by sodium valproate + clobazam 10% (N=4). Highest combination of three AEDs that were prescribed the highest were carbamazepine + Levetiracetam + clobazam and phenytoin + phenobarbitone + sodium Valproate 20% (N=2) The highest medication adherence was found in patients who were on single AEDs and the lowest adherence was found in the patients who were on more than two AEDs. Conclusion: Antiepileptic drug monotherapy was highly prescribed as compare to polytherapy. Phenytoin was the most commonly prescribed AEDs followed by carbamazepine and highly prescribed single AEDs were found to be carbamazepine. The patients who were on single epileptic drugs showed the highest adherence as compared to the patients with more than two AEDs.

scholarly journals A STUDY OF DRUG UTILIZATION AND POTENTIAL DRUG-DRUG INTERACTIONS IN OUTPATIENT PHARMACY OF A TERTIARY CARE TEACHING HOSPITAL: A CROSS-SECTIONAL OBSERVATIONAL STUDY.

2020 ◽  
pp. 1-3
Author(s):  
Adit Deshmukh ◽  
Sangeeta Dabhade
Keyword(s):  
Observational Study ◽  
Drug Utilization ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Potential Drug ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Antibiotic Drug

Introduction: Drug utilization research evaluates the appropriateness of the prescriptions which is important in clinical practice. Hospital Pharmacy is the place where the data of prescriptions from all the Outpatient departments of the hospital can be gathered under one roof. Methodology: A cross-sectional, observational study was carried out in the Outpatient pharmacy of a tertiary care teaching hospital. The study was conducted over a period of 1 month on 400 prescriptions. Results: Average no of drugs per prescription was 2.40 ± 1.49. 30.25% of prescriptions contained an antibiotic. Beta lactam was the most commonly prescribed class of antibiotics, while Coamoxiclav was the most commonly prescribed antibiotic drug. 78.46% and 67.22% of the drugs were prescribed from NLEM and WHO list, respectively. Total 130 pDDIs were observed in all the 400 prescriptions surveyed, out of which 51 prescriptions were showing at least one pDDI. Conclusion: The rate of prescription of drugs from both the Essential drug lists was satisfactory. No injection was prescribed on OPD basis. Almost 87 % prescriptions were not having any potential drug-drug interaction (pDDI). All these observations highlight the rational prescription of drugs as per WHO Drug use indicators. The study highlights the need to minimize the percentage of antibiotics prescribed. Further studies are warranted to analyse the causes of Polypharmacy observed in some prescriptions in this study and to find ways to minimize it as much as possible.

scholarly journals Study of prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care teaching hospital: an observational study

2018 ◽  
Vol 6 (3) ◽  
pp. 985
Author(s):  
Rohini Gupta ◽  
Apoorva Malhotra ◽  
Pavan Malhotra
Keyword(s):  
Observational Study ◽  
Lower Extremity ◽  
Teaching Hospital ◽  
Symptomatic Relief ◽  
Tertiary Care ◽  
Primary Objective ◽  
Prescribing Pattern ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching

Background: Osteoarthritis(OA) is a major cause of chronic pain and lower extremity disability among the elderly due to its predilection for lower extremity joints such as the knee and hip. Although Paracetomol is the initial drug of choice, NSAIDS are also frequently used in the symptomatic relief of osteoarthritis. But still, there is a need for safe and effective alternative treatments which would provide both symptomatic improvement and disease modifying effects in OA. The primary objective was to study the prescribing pattern of drugs used in the treatment of osteoarthritis.Methods: A cross-sectional, prospective, observational study was conducted on newly diagnosed as well as old treated patients with osteoarthritis from orthopaedic outpatient department in a tertiary care teaching hospital. A total of one hundred and eighty-eight patients were enrolled after screened for the inclusion and exclusion criteria. Data was recorded in a specially designed proforma which include information regarding the demographic profile of the patients and about the pattern of drugs prescribed.Results: Out of one hundred eighty-eight patients who were affected with Osteoarthritis, females (57.9%) were more commonly affected than males (42%). OA knee (77%) either unilateral or bilateral was most commonly affected, followed by hip joint, spine and other joints. NSAIDS were more frequently prescribed in 76.6% patients than paracetamol which was prescribed in only 34 % of patients and that only in combination with NSAIDS and opioids. Various other drugs were also used as adjunct therapies that included gastroprotective agents in 49% of patients, Calcium in 54% of patients, Vitamin D3 supplements in 51% of patients and symptomatic slow acting drugs for OA (SYSADOA) which included diacerin and glucosamine sulfate as combination in 11% of patients.Conclusions: Our study showed Osteoarthritis knee being most common among female patients. Paracetamol and SYSADOA being under prescribed and NSAIDS are the most frequently used drugs in OA. National drug policy is needed to rationalize the drug use and bring awareness among the prescribing doctors. 

Knowledge, Attitude and Practices of Pharmacovigilance among Doctors at a Tertiary Care Teaching Hospital Birgunj, Nepal

Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 14-18
Author(s):  
Smita Singh ◽  
Deependra Prasad Sarraf ◽  
Prabin Singh ◽  
Pragati Poudyel
Keyword(s):  
Teaching Hospital ◽  
Health Care Professionals ◽  
Tertiary Care ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Medical College ◽  
National Medical

Introduction: Pharmacovigilance helps in the detection and prevention of adverse effects of drugs. For the effectiveness of this program, health care professionals should report adverse drug reactions (ADRs) considering it as their moral and professional obligation. The objective of the study was to assess the knowledge, attitude, and practices (KAP) of the doctors towards ADRs and pharmacovigilance in  National Medical College Teaching Hospital (NMCTH), a tertiary care teaching hospital situated in the Narayani zone. Materials and Methods: A cross-sectional study was carried out using a self-administered questionnaire consisting of four parts; first part included a demographic profile of participants, the second part consisted of ten questions for the assessment of the knowledge about pharmacovigilance, third part comprised of six questions on attitude and fourth part consisted of five questions on practice. The results were depicted in the form of percentages for each KAPs questionnaire.   Results: The response rate of participants was 85.16%. Pharmacovigilance was correctly defined by 52%. Department of drug administration was responsible for monitoring ADRs in Nepal was correctly given by 80%. Only 8% had reported ADRs, although 62% had encountered an ADR in their clinical practice. Conclusion: The doctors at NMCTH had a poor KAP towards pharmacovigilance and educational intervention is needed for the proper functioning of this program.

scholarly journals PATTERN OF ADVERSE DRUG REACTIONS IN A TERTIARY CARE TEACHING HOSPITAL: A CROSS-SECTIONAL STUDY

2017 ◽  
Vol 10 (3) ◽  
pp. 170 ◽  
Author(s):  
Sangeetha Raja ◽  
Jamuna Rani R ◽  
Kala P
Keyword(s):  
Adverse Drug Reactions ◽  
Teaching Hospital ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Drug Reactions ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching

ABSTRACTObjective: The aim of this study was to carry out adverse drug reactions (ADRs) monitoring in various departments of a tertiary care teaching hospital.Methods: A cross-sectional study was conducted on ADRs reported in the hospital from December 2012 to May 2013 after obtaining InstitutionalEthics Committee approval.Results: A total of 40 ADRs were reported, 47.50% were males and 52.50% were females. The female adult population was 45%. The majority of ADRswere due to antimicrobial agents especially beta-lactam antibiotics (42.5%) followed by NSAIDs (7.50%). A maximum number of patients (75%)were reported with dermatological manifestations. The department of medicine reported the highest number of ADRs (37.5%). As per Naranjo’sprobability scale, 62.5% reports were assessed as probable. 62.5% reports were documented as mild according to Modified Hartwig’s criteria forseverity assessment.Conclusion: This study was done to sensitize the practicing physicians on the importance of adverse drug monitoring and reporting.Keywords: Pharmacovigilance, Adverse drug reactions, Tertiary care teaching hospital, Antimicrobial agents.

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