scholarly journals A Cross-Sectional Study of Comparative Coronary Angiographic Profile of Successful and Failed Thrombolysis with Tenecteplase Conducted at Osmania General Hospital, Hyderabad

2021 ◽  
Vol 8 (22) ◽  
pp. 1808-1813
Author(s):  
Krishna Malakondareddy Parvathareddy ◽  
Srinivas Ravi ◽  
Jagadeesh Reddy Kolli ◽  
Chethan Bharadwaj

BACKGROUND Acute Myocardial Infarction (AMI) can lead to death, and thrombolytic therapy (TLT) is a common treatment protocol. However, thrombolysis is not always successful, and there are numerous contributing factors. We wanted to compare and contrast the coronary angiographic profile of patients with successful and failed thrombolysis with tenecteplase. METHODS Cases of AMI receiving tenecteplase were categorized as successful and failed thrombolysis groups. Fifty patients in each group were compared for various characteristics such as age, sex, risk factors, time to thrombolysis, LV function, number of coronary vessels involved, angiographic lesion characteristics, thrombolysis in myocardial infarction (TIMI) flow, and to look for features that may predispose to thrombolysis failure. To determine the association between variables, chi-square test and logistic regression were used. RESULTS The mean age in the successful & failed thrombolysis group was 50.72 years and 53.48 years. Gender, diabetes, hypertension, smoking, alcohol, type of MI were not statistically significant for failed thrombolysis. All patients with window period < 3 hrs had successful thrombolysis and most patients with window period > 6 hrs had failed thrombolysis (87.2 %). (P < 0.001). Most patients (75.9 %) with Type A lesions had successful thrombolysis and patients with Type B & C lesions (88.1 %) had failed thrombolysis. (P < 0.001). CONCLUSIONS In patients with longer window periods, failed thrombolysis was more common and was associated with complex coronary lesion morphology. This study reemphasizes the value of early thrombolysis for effective reperfusion and clinical outcome improvement. KEYWORDS Failed Thrombolysis, Tenecteplase, Angiographic Profile

2019 ◽  
Author(s):  
Mohammad Sadati ◽  
Jafar Sadegh Tabrizi ◽  
Ramin Rezapour ◽  
Riaz Alaei Kalajahi

Abstract Background Unintentional injuries in the home are one of the threats to childhood quality of life which is considered as a social determinant of health. Regarding mother's leading role in taking care of the children in Iranian families, the present study was conducted to investigate mothers' home-injury prevention attitude and performance and its contributing factors in Sahand, Iran. Methods This was a cross-sectional study conducted in 2017. Sampling was done using random sampling method among all mothers of children less than five years old who attended the health centers to receive child care services. A valid attitude questionnaire and safety performance checklist were used for data collection. Data were analyzed through SPSS-24 software using descriptive (Frequency, mean, etc.) and inferential statistics (chi-square, Kruskal-Wallis) method. Results The Mean age of mothers was 30.58 (±5.01). About 65% of the mothers held high school diplomas or lower degrees. The mean score of mothers' attitude was calculated to be 72.12(±6.79). More than 58% of the mothers had an appropriate level of attitude. The mothers' injury prevention performance mean score was 66.59 (±12.85). Family socioeconomic status, Mother's age, educational level, and job, father's job, age and gender of the child were the contributing factors (p<0.05). Conclusions Most of the mothers had an appropriate level of home-injury prevention attitude and low level of performance. Deprived residency areas should be considered for higher support to prevent injuries. Strengthening Primary Health Care system in safe communities could have a significant role in child safety promotion through mothers KAP promotion.


Open Medicine ◽  
2008 ◽  
Vol 3 (2) ◽  
pp. 221-224 ◽  
Author(s):  
Aleksandra Jovic-Vranes ◽  
Bjegovic Vesna ◽  
Vranes Boris ◽  
Milic Natasa

AbstractThe study was undertaken to assess job satisfaction among health care workers (HCWs) who work with disabled patients and to identify the factors that contribute to their job satisfaction. This was a cross-sectional study conducted at nine rehabilitation centers in Serbia. The study sample consisted of doctors, nurses, physiotherapists, and other HCWs (social workers, work and speech therapists, and psychologists). A self-administrated questionnaire was distributed to 170 HCWs. Chi square testing and multivariate logistic regression analyses were applied. The response rate was 97.1% (165/170). Overall job satisfaction was reported by 22.4% of the respondents and was associated with hospital politics (odds ratio [OR], 4.16; 95% confidence interval [CI], 1.13–15.30], personal relationships (OR, 13.96; 95% CI, 4.07–47.92) and the feeling of being able to provide a good quality of care (OR, 5.24; 95% CI, 1.62–16.99). Profession, age, and gender did not affect job satisfaction. In conclusion, the results show very low job satisfaction among HCWs. Improving contributing factors may lead to higher job satisfaction and a better quality of health care.


Author(s):  
Beenu Bista ◽  
Soni Shrestha ◽  
Bipanda Gyawali

Myopia is the most prevalent refractive error among the children leading to blindness. The prevalence rate is increased since few years back due to increase in modern technologies and mode of study among children. This descriptive cross sectional study aims to explore factors contributing to myopia among children visiting refractive clinic/refractive department of Nepal Eye Hospital. Non probability purposive sampling method and 206 children were used for this study. Structured questionnaire were used along with the children and their parents. Chi-square test was used for finding the association with the contributing factors. The study population varies between the ages of 5 to 17 years with the mean age±12 and mostly affecting the children above 10 years. Myopia is significantly associated with religion, ethnicity, heredity, parent’s level of education. Income status of family, reading at dim light is significantly associated with myopia as p-value is <0.0001. Myopia in children attending refractory OPD of Nepal Eye Hospital was associated with heredity, socio-economic status and level of education of parent; continue reading, additional classes, watching video/ television, using computer or cell phone, sports (football, cricket), dim light and not associated with residential area, type of school, night lightness, dietary pattern and ocular hygiene; therefore parents along with children and teachers should be given awareness program about early screening and its preventive measures.Journal of Manmohan Memorial Institute of Health Sciences Vol. 2 2016 p.61-69


Author(s):  
Juhi Lohiya ◽  
Vrinda Saxena ◽  
Garima Bhambhani ◽  
Shweta Chaturvedi ◽  
Swapnil Jain ◽  
...  

Background: The rapid spread of the COVID-19 pandemic has loaded remarkable psychological stress on people around the world, predominantly the Health Care Professionals (HCPs). The present study aimed to assess anxiety and fear of getting infected among HCPs working during the current viral outbreak. Also, doctors' knowledge about various practice modifications to combat the novel coronavirus disease (COVID-19) outbreak has been evaluated.Methods: A cross-sectional study was conducted on Health care professionals (HCPs) of Madhya Pradesh India using an online survey. A pretested and pre-validated questionnaire was designed on Google forms and link generated was shared through social media. A total of 320 doctors from different cities of Madhya Pradesh have participated in the study. A Chi-Square and Spearman Correlation test was applied using SPSS version 25.Results: Present Study reveals that more than two-thirds of HCPs (80%) were anxious and worried about the overwhelming effect of COVID-19. Among HCPs, dental professionals (61%) unfolded greater fear and anxiety level than the medical professionals. The majority of participants (92%) were updated with good knowledge and awareness of recent changes in the treatment protocols regarding the COVID-19 pandemic. However, the implementation of modifying treatment protocol was recorded as 71%.Conclusions: High psychosomatic implications of COVID -19 outbursts were seen in HCPs while working in their respective fields. So providing psychological first aid is a significant care component for populations that have been victims of emergencies and disasters.


2021 ◽  
Vol 2 (2) ◽  
pp. 72-76
Author(s):  
Aisha Bashir ◽  
Asma Salam ◽  
Aasia Kanwal

Background: Acute myocardial infarction (AMI) is one of the leading causes of death in developed and developing countries. Age is an important non-modifiable risk factor for acute myocardial infarction. Objectives: The objective of the study was to explore the relationship of advancing age with the risk of acute myocardial infarction. Methods: It was a cross-sectional study conducted in 2019 after getting approval from Institutional Review board of University of Health Sciences, Lahore. Written informed consent and thorough history was taken from the study participants. Group 1 included 45 AMI patients aged 20-60 years. Group 2 included 45 healthy individuals aged 20-60 years. Independent sample t test and chi-square tests were applied for analysis of data. Results: Mean age was significantly higher in AMI patients (50.52±7.31) as compared to healthy controls (30.67±7.20). The risk of AMI increases with advancing age (p<0.001, OR= 2.78). Conclusions: Advancing age is an important risk factor for acute myocardial infarction.


2012 ◽  
Vol 7 (1) ◽  
pp. 13-17
Author(s):  
Priyanka Garg ◽  
Jayant Kumar ◽  
Raghuveer Choudhary ◽  
VK Chawla

Background: Many reports have appeared in recent years showing an association between blood  groups and Myocardial Infarction. Clinical studies have shown a significant association between MI  and blood group B.Objective: To investigate correlation of ABO blood groups with risk of MI.Methods: The present cross sectional study analyzed ABO blood group among total 400 subjects of  any age from the local population of Jodhpur city from July to December 2011.Among them 200  subjects were normal health (135 male and 65 female) students of Dr. S.N. Medical College, Jodhpur  and another 200 (135 male, 65 female) were MI patients admitted in the CCU of Mathura Das  Memorial (MDM) Hospital, Jodhpur. ABO blood group of all subjects were determined by slide  agglutination method. Risk of MI was expressed by risk ratio. Data were analyzed by one sample chi  square test.Results: The results obtained in this study showed that the prevalence of MI in blood  group B is significantly higher than in all other ABO blood groups.Conclusion: The results may  conclude that there is a significant association between MI and blood group B. So this study reveals  MI risk is associated with the blood group B. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11154 J Bangladesh Soc Physiol. 2012, June; 7(1): 13-17


2017 ◽  
Vol 2017 ◽  
pp. 1-9
Author(s):  
Dessalegn Asmelashe Gelayee ◽  
Gashaw Binega Mekonnen

Background. Dispensing errors are inevitable occurrences in community pharmacies across the world. Objective. This study aimed to identify the community pharmacists’ perception towards dispensing errors in the community pharmacies in Gondar town, Northwest Ethiopia. Methods. A cross-sectional study was conducted among 47 community pharmacists selected through convenience sampling. Data were analyzed using SPSS version 20. Descriptive statistics, Mann–Whitney U test, and Pearson’s Chi-square test of independence were conducted with P≤0.05 considered statistically significant. Result. The majority of respondents were in the 23–28-year age group (N=26, 55.3%) and with at least B.Pharm degree (N=25, 53.2%). Poor prescription handwriting and similar/confusing names were perceived to be the main contributing factors while all the strategies and types of dispensing errors were highly acknowledged by the respondents. Group differences (P<0.05) in opinions were largely due to educational level and age. Conclusion. Dispensing errors were associated with prescribing quality and design of dispensary as well as dispensing procedures. Opinion differences relate to age and educational status of the respondents.


Author(s):  
T. Dhivyaa ◽  
P. Kalyani ◽  
A. John William Felix

Background: Refractive errors are one of the most common causes of visual impairment worldwide. Uncorrected, under corrected and undetected refractive errors among school-going children are the most significant problem in developing countries like India. Schools are the best place for early detection of ocular morbidity. Myopia, hypermetropia and astigmatism are the three main types of refractive errors, of which myopia is the most common type in school-going children.Methods: This descriptive cross-sectional study was carried out for the period of 6 months from October 2019 to March 2020 among school-going children in the field practice area of Chidambaram. 575 students from two government and 2 private schools were selected conveniently. Data were collected using a pre-tested, semi-structured questionnaire and analysed using Statistical Package for social sciences (SPSS) software version 23. Descriptive statistics were used and a Chi-square test of significance was applied.Results: The prevalence of myopia was found to be 12.9%. There is a significant association between the frequency of reading hours, time spent on outdoor activities and mobile usage and the presence of myopia (p<0.05).Conclusions: The risk factors like hours of reading books, time spent on outdoor activities and mobile usage are the contributing factors for the development of refractive error like myopia. They are easily detectable through the program on eye screening of school children. 


2018 ◽  
Vol 25 (05) ◽  
pp. 759-763
Author(s):  
Raj Kumar Sachdewani ◽  
Lal Chand Dingra ◽  
Aijaz Hussain Memon

Objectives: To find a relationship between acute ST elevation myocardialinfarction (STEMI) and two major risk factors i.e. diabetes type 2 and hypertension in adultpatients admitted in cardiology department of Ghulam Muhammad Mahar Medical CollegeSukkur. Study Design: Cross-sectional study. Study Setting: Department of Cardiology,Ghulam Muhammad Mahar Medical College Sukkur. Period: October 2016 to March 2017. 6months. Material and Methods: Total of 764 patients aged 18-80 years were included in thestudy population on bases of history of chest discomfort and sudden ST elevation MI (STEMI).Those patients with unstable angina and those cases which presented with Q waves wereexcluded from study population. Blood pressure and blood sample were taken and analyzedin the institution laboratory. Results: Off 764 anterior wall Myocardial infarction (includingextensive) was seen in 367(48%) while inferior wall Myocardial infarction (including RV andposterior) was recorded in 397(52%) of the study population. 118 (15.44%) were hypertensiveand also had diabetes off which 8.11% were female and chi square test reveals a relationshipbetween sex and diabetes and hypertension in the study population. Conclusion: A relationshipof hypertension and diabetes with STEMI is there. Primary prevention and proper screenprogram needs to be in place to identify the submerge part of the iceberg.


2016 ◽  
Vol 5 (2) ◽  
pp. 240
Author(s):  
Jamal Qaddumi ◽  
Margo Holm ◽  
Abdullah Alkhawaldeh ◽  
Mohammed Albashtawy ◽  
Omar AL Omari ◽  
...  

Hypertension and pre-hypertension are major contributors to morbidity. Early detection of hypertension and pre-hypertension among adolescents may prevent their complications. A cross-sectional study was conducted to estimate the prevalence of hypertension and pre-hypertension among adolescents attending government high schools in Nablus city, Palestine and to identify associated factors, in a sample of 487 adolescents aged 16-18 years in the year 2016. Associations between hypertension, pre-hypertension and known contributing factors were analyzed with Chi-square tests.The prevalence of hypertension and pre-hypertension were 59.2%. Body Mass Index (BMI) was significantly associated with a greater prevalence of hypertension (normal weight 13.1%, overweight 33.3%, and obesity 54.8 %) and pre-hypertension (normal weight 40.4%, overweight 47.4% and obesity 40.5%).The results confirmed a prevalence of hypertension and pre-hypertension among adolescents. Of known contributing factors studied, gender, age, BMI, and family history of hypertension were significantly associated with a greater prevalence of hypertension or pre-hypertension.


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