scholarly journals Morphometric indices of secretory epithelium of main prostate glands in people 13-88 years old

2018 ◽  
Vol 7 (3) ◽  
pp. 39-45
Author(s):  
I. A. Piatsko ◽  
A. K. Usovich
Keyword(s):  
Epithelial Cells ◽  
Morphometric Parameters ◽  
Autopsy Material ◽  
Late Adulthood ◽  
Projection System ◽  
Secretory Epithelium ◽  
Age Related ◽  
Morphometric Methods ◽  
Hematoxylin And Eosin ◽  
Age Range

The aim of the study was to study the age-related changes in the epithelium of the end pieces of the prostate main glands, in all its structural lobules in the age range from adolescence late adulthood age. Materials and methods. Histological, morphometric methods were used to study the secretory epithelial cells of the end pieces of the main glands on prostate preparations of 77 men aged 13-88 years, on autopsy material. The histological sections were stained with hematoxylin and eosin, studied using a Leica DM-2000 microscope with a video projection system, using the Leica "LAS V3.6" application morphometric program. Shape and sizes of the secretory epithelial cells of the end pieces of the prostate main glands in pairs of anteromedial, superomedial, inferoposterior, inferolateral structural lobes (zones) were determined. To evaluate the results obtained, nonparametric methods of mathematical statistics were used (Wilcoxon W-test for comparison of two independent samples, Kraskel-Wallis H-test for multiple comparisons, Dann's test with Bonferroni amendment). Results. The differences of the morphometric parameters of secretory epithelial cells in pairs of anteromedial, superomedial, inferoposterior, inferolateral structural lobes (zones) of the human prostate within each of the studied age periods and changes of these parameters according to the age periods from adolescents to late adulthood age were detected. Conclusion. The development and growth of secretory epithelium in all structural lobules of the prostate were observed in the age interval 13-35 years, and the atrophic processes begin at the age of 36, but these changes occur asynchronously, both within one end piece of the gland and in different structural lobules. The changes of the epithelium in the prostate does not always correspond to the calendar age of men.

scholarly journals Morphological characteristic of premature infants’s kidneys with opened Ductus Arteriosis (by the autopsy).

Morphologia ◽  
2021 ◽  
Vol 15 (1) ◽  
pp. 28-38
Author(s):  
T.P. Borysova ◽  
I.V. Tverdokhlib ◽  
O.Yu. Obolonska ◽  
A.S Korolenko ◽  
K.I. Diahovets ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Premature Infants ◽  
Inverse Relationship ◽  
Ductus Arteriosus ◽  
Autopsy Material ◽  
Hemodynamic Changes ◽  
Morphometric Methods ◽  
Hematoxylin And Eosin ◽  
Superficial Area ◽  
Late Stages

Background. Kidney has protracted nephrogenesis and depend on hemodynamic changes on the highest level in support of natural transition to extrauterine circulation. Fetal communications like Ductus Arteriosus take part in the shunting from the aorta to the pulmonary artery. Increase of this shunting of the blood leads to hyperperfusion with hypoxic changes of some development systems of organs with protracted morphogenesis so like kidneys. Objective. To determine the features of postnatal morphogenesis of the kidneys in premature infants with a gestational age of 25 to 35 weeks on the background of an open ductus arteriosus. Methods. 21 autopsy material premature infant’s kidney which were fixed by 10%-formalin and then were subjected to the standard histological procedures. Slides were stained by hematoxylin and eosin. We used the complex of histological and morphometric methods. There were created 3-demenshional models of kidney’s fragments. We carried out biometrical and statistical analysis. Results. During our research it was determines that the changes of the volume of the functional parenchyma of the kidney and the diameter of the Ductus Arteriosus became in inverse relationship. The wider the duct the smaller the volume of the functional parenchyma because of atrophic and necrotic changes during the late stages of glomerulo- and tubulogenesis. These changes could be distinguished by the quantitative density of development on three germinate layers of the cortex of kidney. Сonclusion. Summing up, it determined the retardation of glomerulogenesis particularly superficial area of the cortex because of the opened Ductus Arteriosus.

Asymmetry in Event-Related Potentials to Simulated Auditory Motion in Children, Young Adults, and Seniors

2002 ◽  
Vol 13 (01) ◽  
pp. 001-013 ◽  
Author(s):  
James Jerger ◽  
Rebecca Estes
Keyword(s):  
Young Adults ◽  
Right Hemisphere ◽  
Apparent Movement ◽  
Event Related Potentials ◽  
Auditory Evoked Responses ◽  
Age Related ◽  
Related Potentials ◽  
Velocity Information ◽  
The Right ◽  
Age Range

We studied auditory evoked responses to the apparent movement of a burst of noise in the horizontal plane. Event-related potentials (ERPs) were measured in three groups of participants: children in the age range from 9 to 12 years, young adults in the age range from 18 to 34 years, and seniors in the age range from 65 to 80 years. The topographic distribution of grand-averaged ERP activity was substantially greater over the right hemisphere in children and seniors but slightly greater over the left hemisphere in young adults. This finding may be related to age-related differences in the extent to which judgments of sound movement are based on displacement versus velocity information.

scholarly journals The Positive Legacy of Vision Loss: Pathways to Posttraumatic Growth

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 616-617
Author(s):  
Corinna Tanner ◽  
Michael Caserta ◽  
Jia-Wen Guo ◽  
Margaret Clayton ◽  
Paul Bernstein ◽  
...  
Keyword(s):  
Posttraumatic Growth ◽  
Cognitive Processing ◽  
Mixed Method ◽  
Vision Loss ◽  
Social Issues ◽  
Qualitative Interviews ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Severe Vision Loss ◽  
Age Range

Abstract This mixed method study describes posttraumatic growth (PTG) accruing form experience with vision loss caused by severe age related macular degeneration (AMD) and explores relationships between depression, social support, and cognitive processing, on the path to PTG. Research describing the psychological and social issues surrounding AMD has focused on negative outcomes. However, learning from highly challenging experiences, such as vision loss, can offer benefits. In this study, these included an increased sense of personal strength, increased spirituality, and empathy for others (all domains of PTG). 89 participants with severe vision loss (mean age = 85.3 years, age range = 74–98 years) completed the interviewer-administered composite questionnaire, which identified elements of Tedeschi and Calhoun’s model of PTG. Relationships between variables were examined using path analysis. Findings were contextualized with data from 15 qualitative interviews. Findings underscored the importance of supportive others and deliberate cognitive processing in the path to PTG.

scholarly journals The effect of intrinsic physiological traits on diapause survival and their underlying mechanisms in an annual bee species Bombus impatiens

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Erin Treanore ◽  
Etya Amsalem
Keyword(s):  
Oxidative Stress ◽  
Life Stage ◽  
Mass Gain ◽  
Nutrient Acquisition ◽  
Bombus Impatiens ◽  
Factors Affecting ◽  
Age Related ◽  
The Face ◽  
Underlying Mechanisms ◽  
Age Range

Abstract In the face of insect declines, identifying phases of the life cycle when insects are particularly vulnerable to mortality is critical to conservation efforts. For numerous annual insect groups, diapause is both a key adaptation that allows survival of inhospitable conditions and a physiologically demanding life stage that can result in high rates of mortality. As bees continue to garner attention as a group experiencing high rates of decline, improving our understanding of how annual bees prepare for diapause and identifying factors that reduce survival is imperative. Here, we studied factors affecting diapause survival length and their underlying mechanisms using an economically and ecologically important annual bee species, Bombus impatiens. We examined how age and mass upon diapause onset correlate with diapause survival length, and the mechanistic role of nutrient acquisition and oxidative stress post pupal eclosion in mediating these effects. Our findings show that both age and mass were strong predictors of diapause survival length. Heavier queens or queens in the age range of ~6–17 days survived longer in diapause. Mass gain was attributed to increases in lipid, protein and glycerol amounts following pupal eclosion, and the ability to deal with oxidative stress was significantly compromised in older pre-diapause queens. Our results demonstrate that age-related shifts in bee physiology and timing of nutrient acquisition may both be critical factors driving diapause survival.

Scaphechinus mirabilis extract effectively inhibits the proliferation of BPH-1 and LNCaP prostate epithelial cells

2021 ◽  
Vol 11 ◽  
Author(s):  
Kyung-Hyun Kim ◽  
Geum-Lan Hong ◽  
Shanika Karunasagara ◽  
Ju-Young Jung
Keyword(s):  
Epithelial Cells ◽  
Sea Urchins ◽  
Specific Antigen ◽  
Marine Species ◽  
Lncap Cells ◽  
Caspase 9 ◽  
Scaphechinus Mirabilis ◽  
Age Related ◽  
Prostate Epithelial Cells ◽  
Related Proteins

Background: Benign prostatic hyperplasia (BPH) is an age-related disease characterized by progressive proliferation of prostate stromal and epithelial cells. While the precise etiology of BPH is still not clear, the proliferation of epithelial cells has been implicated in the development of the disease. Scaphechinus mirabilis (S. mirabilis) is a marine species belonging to the order Clypeasteroida, which contains flat, burrowing sea urchins. Objective: This study examined the effects of S. mirabilis extract on the proliferation of BPH-1 and LNCaP prostate epithelial cells. Methods: BPH-1 and LNCaP cells were cultured and treated with S. mirabilis extract (50, 100, and 200 μg/ml). The viability of cells treated with S. mirabilis extract was determined by the MTT assay. Results: Proliferation of BPH-1 and testosterone-induced LNCaP cells was inhibited by treatment with S. mirabilis extract. S. mirabilis extract suppressed the expression of androgen-related proteins, such as androgen receptor, prostate-specific antigen, and 5α-reductase 2. S. mirabilis extract inhibited testosterone-induced proliferation. Moreover, S. mirabilis extract induced apoptotic responses by regulating the expression of caspase-9, Bcl-2, and Bax. Conclusion: These findings suggest that S. mirabilis extract abrogated the expression of androgen-related proteins by inducing apoptotic responses, which could be valuable for the design of new therapeutic agents for the treatment of BPH.

Emotion regulation from early adolescence to emerging adulthood and middle adulthood

2014 ◽  
Vol 38 (2) ◽  
pp. 182-194 ◽  
Author(s):  
Peter Zimmermann ◽  
Alexandra Iwanski
Keyword(s):  
Emotion Regulation ◽  
Early Adolescence ◽  
Methodological Approach ◽  
Developmental Changes ◽  
Middle Adulthood ◽  
Emotion Regulation Strategies ◽  
Age Related ◽  
Emotion Regulation Strategy ◽  
Regulation Strategies ◽  
Age Range

Despite the growing research on emotion regulation, the empirical evidence for normative age-related emotion regulation patterns is rather divergent. From a life-span perspective, normative age changes in emotion regulation may be more salient applying the same methodological approach on a broad age range examining both growth and decline during development. In addition, emotion-specific developmental patterns might show differential developmental trends. The present study examined age differences in seven emotion regulation strategies from early adolescence (age 11) to middle adulthood (age 50) for the three emotions of sadness, fear, and anger. The results showed specific developmental changes in the use of emotion regulation strategies for each of the three emotions. In addition, results suggest age-specific increases and decreases in many emotion regulation strategies, with a general trend to increasing adaptive emotion regulation. Specifically, middle adolescence shows the smallest emotion regulation strategy repertoire. Gender differences appeared for most emotion regulation strategies. The findings suggest that the development of emotion regulation should be studied in an emotion-specific manner, as a perspective solely on general emotion regulation either under- or overestimates existing emotion-specific developmental changes.

The ‘open-earedness’ hypothesis and the development of age-related aesthetic reactions to music in elementary school children

2008 ◽  
Vol 25 (2) ◽  
pp. 121-138 ◽  
Author(s):  
Reinhard Kopiez ◽  
Marco Lehmann
Keyword(s):  
Elementary School ◽  
School Children ◽  
Elementary School Children ◽  
Classical Music ◽  
Rating Scale ◽  
Avant Garde ◽  
Musical Preference ◽  
Age Related ◽  
Age Range ◽  
Musical Styles

This study investigates age-related changes in musical preference in elementary school children. The tolerance towards unconventional musical styles has been called ‘open-earedness’ (Hargreaves, 1982a), and it is assumed to decline with increasing age. Musical preferences of 186 students from grade 1 to 4 (age range: 6–10 years) were measured by using a 5-point iconographic rating scale. Eight sound examples were presented in a sound questionnaire. Results showed a decline of open-earedness for unconventional music (classical, ethnic and avant-garde music) from grade 1 to 2 (age: 7–8 years). However, this effect disappeared when classical music was excluded from data analysis. Only a few absolute rejections of unconventional musical styles were found, and the mean preference ratings did not exceed the neutral mean range. Future studies will have to consider additional factors of influence to make clear predictions about the point in time when this transition occurs.

scholarly journals The Development of Expressive Drawing Abilities during Childhood and into Adolescence

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Delphine Picard ◽  
Christophe Gauthier
Keyword(s):  
Cognitive Development ◽  
Sample Size ◽  
Comprehensive View ◽  
Age Related ◽  
Developmental Shift ◽  
Complex Forms ◽  
Age Range ◽  
Age Related Changes ◽  
The Way

The way children portray emotions in their drawings of human and nonhuman topics is assumed to reflect their artistic, emotional, and cognitive development. This study was designed to investigate the development of expressive drawings during childhood and into adolescence, using a large age range (5–15 years) and sample size (N=480), so as to provide a precise and comprehensive view of age-related changes in children’s ability to produce expressive drawings. More specifically, we focused on children’s developing ability to use the techniques of literal and metaphorical expression, either alone or in combination. We also examined the effects of sex, topics (house, tree, or person), and the depicted emotion (happiness or sadness) on the use of each expressive technique. The main findings were that there is a developmental shift between childhood (5–10 years) and adolescence (11–15 years) in the use of expressive techniques, from simple (literal) to more complex forms of expression (metaphorical).

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