scholarly journals Blood Donor Deferrals for Malaria in Iran: A Five-Year Retrospective Study

Author(s):  
Ahmad MARDANI ◽  
Hossein KESHAVARZ

Background: Malaria is one of the most important transfusion-transmitted infections (TTIs) worldwide. To prevent the occurrence of transfusion-transmitted malaria (TTM), potential blood donors with a history of malaria or travel to, or residence in, malarious areas are permanently or temporarily deferred from donating blood. The objective of the present study was to evaluate the blood donor deferrals for malaria in Iran. Methods: This descriptive cross-sectional study was conducted in the Iranian Blood Transfusion Organization (IBTO) from 21 Mar 2011 to 19 Mar 2016 (5 yr). The data were collected and extracted from IBTO comprehensive database, namely Negareh, and then recorded in a structured template form. Statistical analysis was performed using SPSS. Results: Of the 12,790,859 blood donation volunteers, 23,084 (0.18%) were deferred due to the risk of malaria. More than 90% of malaria-deferrals were because of travel to and residence in malaria endemic areas. Among the malaria-deferred volunteers, 22,139 (95.91%) were male and 945 (4.09%) were female; 2,053 (8.89%) were permanently deferred, while 21,031 (91.11%) were temporarily deferred. The highest malaria-deferral rates were observed in South Khorasan (0.82%), Razavi Khorasan (0.79%) and Yazd (0.54%) provinces, respectively. Conclusion: Given the prevalence of malaria in neighboring countries (Pakistan and Afghanistan) and several provinces of Iran and the increasing human migration and movement between malaria non-endemic and endemic areas, the malaria-deferral rate might be higher than 0.18% in Iran. Thus, the changing, as well as the precise and accurate implementation of donor selection process must be considered in all blood transfusion centers of Iran.

2021 ◽  
Vol 8 (29) ◽  
pp. 2615-2619
Author(s):  
Indu Pachampully Kumaran ◽  
Archana K.A ◽  
Meena Dharmadas ◽  
Sasikala Nadanganan ◽  
Anu Kumar B ◽  
...  

BACKGROUND Even in the presence of sufficient voluntary blood donors, the need of blood is not met yet. We wanted to evaluate the causes that hinder the smooth functioning of well-maintained blood transfusion services (BTS). METHODS This is a population based cross-sectional study conducted among blood donors from voluntary outreach blood donation camp for period of one year. Total 1536 blood donors from 32 blood donation camps were subjected to study for the sociodemographic characteristic and their knowledge of blood donation. Statistical analysis of data was done using Microsoft Excel, analysed using statistical package for social sciences (SPSS) ver.16 software. RESULTS A total of 32 blood donation camps were conducted during the study period that provided 1536 donors. In most of the camps, male donors (75 %) were more than female donors. Donors of age group of 30 to 39 years (43.9 %) were more when compared to others. Donors those who were married accounted for 79.9 %. Blood donors of Hindu religion (53 %) were more. CONCLUSIONS The main hindrance for blood donor motivation is lack of knowledge. Literacy and chance to mingle in society have a positive effect on blood donor motivation. Targeting of effective donor motivation, recruitment, and retention were attained by conducting awareness classes, seminars, workshops, and visual communication modalities. KEYWORDS World Health Organization, Altruistic Blood Donor, Blood Transfusion Services, Transfusion Transmitted Infections, Blood Components and Plasma Derivatives, Director General of Health Services (DGHS), National Blood Transportation Council (NBTC)


2018 ◽  
Vol 10 (1) ◽  
pp. e2018041 ◽  
Author(s):  
Arzouma Paul YOODA ◽  
Serge Theophile SOUBEIGA ◽  
Kompingnin Yacouba NEBIE ◽  
Birama DIARRA ◽  
Salam SAWADOGO ◽  
...  

Background and ObjectiveThe improved performance of serological tests has significantly reduced the risk of human immunodeficiency and hepatitis B and C viruses transmission by blood transfusion, but there is a persistence of residual risk. The objective of this study was to evaluate the impact of multiplex PCR in reducing the risk of residual transmission of these viruses in seronegative blood donors in Burkina Faso.MethodsThis cross-sectional study was conducted from March to September 2017. The serological tests were performed on sera using ARCHITECTSR i1000 (Abbot diagnosis, USA). Detection of viral nucleic acids was performed by multiplex PCR on mini-pools of seronegative plasma for HBV, HCV and HIV using SaCycler-96 Real Time PCR v.7.3 (Sacace Biotechnologies). Multiplex PCR-positive samples from these mini-pools were then individually tested by the same method.Results A total of 989 donors aged 17 to 65 were included in the present study. "Repeat donors" accounted for 44.79% (443/989). Seroprevalences for HIV, HBV, and HCV were 2.53% (25/989), 7.28% (72/989) and 2.73% (27/989), respectively. Of the 14 co-infections detected, HBV/HCV was the most common with 0.71% (7/989) of cases. Of 808 donations tested by multiplex PCR, 4.70% (38/808) were positive for HBV while no donation was positive for HIV or HCV.Conclusion: Our study showed a high residual risk of HBV transmission through blood transfusion. Due to the high prevalence of blood-borne infections in Burkina Faso, we recommend the addition of multiplex PCR to serologic tests for optimal blood donation screening.


2018 ◽  
Vol 9 (6) ◽  
pp. 62-67 ◽  
Author(s):  
Jasim N Al-Asadi ◽  
Asaad Q. Al-Yassen

Background: Young students can play a fundamental role in blood donation to save lives of many people. Therefore, studying factors contributing to their knowledge, attitude and practice of blood donation is essential.Aims and Objectives: To evaluate the knowledge and attitude of Basrah University students about blood donation.Materials and Methods: This descriptive cross-sectional study involved students of two colleges in Basrah University. It was carried out during the period from January to April 2017. A non-probability purposive sampling method was used in selecting the participants for this study. Information on socio-demographic characteristics, knowledge and attitude towards blood donation were collected through a structured self-administered questionnaire.Results: A total of 422 students were targeted, of these 393 (93.1%) completed the questionnaire.Only 51 (13%) of total respondents had a history of blood donation, of those 64.7% donated only once. The most mentioned reasons behind not donating were; not being asked to donate (24.6%), inconsideration of donation (11.1%), and fear of drawing blood (8.8%). Adequate knowledge was detected in 66.7% and positive attitude in 68.7%. Students of College of Medicine were younger, more knowledgeable, and donate more than those of College of Administration and Economics.Conclusion: A substantial number of the university students had inadequate blood donation knowledge. Education programs and motivational campaigns should be enhanced.Asian Journal of Medical Sciences Vol.9(6) 2018 62-67


2014 ◽  
Vol 21 (06) ◽  
pp. 1113-1116
Author(s):  
Nasira Naseem ◽  
Ijaz-Ul-Haque Taseer ◽  
Sohail Safdar

Objective: To see the frequency of anemia in pregnant ladies and its possible outcomes. Study design: Descriptive cross sectional study. Setting: Fatima Jinnah Women Hospital, Multan. Duration of study: Six months. Material and method: This prospective cross sectional study was conducted at Gynae and Obst. OPD at Fatima Jinnah Women Hospital, Multan. Non probability convenient sampling technique was used. All the pregnant women between 20-35 years irrespective of gestational age or any concurrent illness having parity upto 5 were registered for the study after getting written consent for participation. The pregnant ladies were evaluated by asking history of blood loss, parity, multiple pregnancy, worm infestation, use of NSAIDS and blood transfusion. They were especially asked about dietary habits which were rated as good, average and poor. Their socio economic status was assessed and was placed into high, middle and low income groups. Blood samples were drawn for blood counts and hemoglobin estimation in all the women presenting at hospital. Reflotron photometer, Roche Diagnostic was used for the blood testing. A cut off value of< 11 g/dl irrespective of duration of pregnancy was used for anemia. Peripheral blood film was examined for RBC morphology. Mean corpuscular volume (MCV) was used to categorize into micorcytic (< 76fl), macrocytic (>98fl) and normocytic (78-98fl). Fetal well being was evaluated by serial abdominal ultrasounds. Results: Three hundred pregnant women attending Gyne and Obst. OPD, Fatima Jinnah Women Hospital, Multan, were registered according to the study protocol. The duration of the study was 6 months. Maternal age was between 25-35 years. 86 % women were multiparous, 79% women presented during 3rd trimester, 15% during the 2nd trimester and 6% during 1st trimester. Thirty eight percent women had hemoglobin 8-9.9 g/dl, 48% had from 7-7.9 g/dl and 10%were falling between 5-7 g/dl. Eighty eight percent had microcytic hypochromic anemia, 12% with dimorphic picture and 4% were having low MCV and MCH but normal MCHC and these were referred for hemoglobin electrophoresis. Fifty eight percent had monthly income 2-4 thousands rupees and only 10% were earning 4-10 thousands per month. Seventy eight percent had poor diet and 22% had an average and no women were fit into the criteria for good diet. History of breast feeding was positive in 92% of the women. History of use of iron supplement was also asked, 28% had used various preparations of iron and folate for a variable period from 1-4 months, 72% never used hematinic supplements. History of previous blood transfusion during pregnancy and labour was present in 16% of the women. Three percent had fetal growth retardation. Conclusions: Prevalence of anemia during 3rd trimester of pregnancy in is high our society. It can have significant effects on maternal and fetal out come. It is a preventable cause which can be treated easily. Poverty and lack of education are the most important causes of anemia during pregnancy.


2020 ◽  
Vol 15 (1) ◽  
pp. 71-74
Author(s):  
AKM Shafiqur Rahman ◽  
Md Arifuzzaman ◽  
Md Mehedhi Hasan Shourov ◽  
Farzana Zafreen

Introduction: Blood transfusion is a significant life-saving intervention in the present era of patient management system. As the blood and blood products are a potential source of infections and the necessity of transfusion is increasing day by day, transfusion transmissible infections have become a major threat to the system of ensuring safe transfusion. Objectives: To find out the sero-prevalence of Hepatitis B, Hepatitis C, HIV, Syphilis and Malaria parasite among the blood donors and to ascertain risk behaviour of the blood donors. Materials and Methods: This descriptive cross-sectional study was conducted on purposively selected 115 blood donors at Armed Forces Institute of Pathology (AFIP) during the period of 1st September to 31st December 2011. Results: The study revealed among 115 blood donors 7.8% were HBsAg positive. More than half of the HBsAg positive cases 66.67% were from civilian. None of the respondents was found positive for anti-HCV, VDRL, Malaria and anti-HIV. All of the donors in this study were voluntary donors. The sample studied had a mean age of 28.03 ± 6.79 years and 90.5% of donors were belongs to age group 18-37 years and female was only 6.1%. Most of the donors (49.5%) were military personnel,86%above SSC educated and 22.6% had visited abroad. Regarding risk behaviour 38.3% had the history of undertaking dental procedure, 0.9% were found undertaking blood transfusion, 2.6% had the history of illicit sex and 29.6% had the history of suffering from jaundice and among them only 1.7% were found HBsAg positive. Conclusion: The study finding demands motivation against unnecessary blood transfusion. It also emphasize health education programme among peoples having risk behaviour. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 71-74


PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261155
Author(s):  
Alexander Nersesov ◽  
Arnur Gusmanov ◽  
Byron Crape ◽  
Gulnara Junusbekova ◽  
Salim Berkinbayev ◽  
...  

Background & aims Kazakhstan has implemented comprehensive programs to reduce the incidence of Hepatitis B and Hepatitis C. This study aims to assess seroprevalence and risk factors for HBsAg and anti-HCV positivity in three large regions of Kazakhstan. Methods A cross-sectional study was conducted in three regions geographically remote from each other. Participants were randomly selected using a two-stage stratified cluster sampling and were surveyed by a questionnaire based on the WHO STEP survey instrument. Blood samples were collected for HBsAg and anti-HCV testing. Results A total of 4,620 participants were enrolled. The seroprevalence was 5.5% (95%CI: 3.6%-8.4%) for HBsAg and 5.1% (95%CI: 3.5%-7.5%) for anti-HCV antibodies. Both were more prevalent in the western and northern regions than in the southern. A history of blood transfusion was significantly associated with anti-HCV presence, with odds ratios (ORs) of 2.10 (95%CI: 1.37–3.21) and was borderline associated with HBsAg 1.39 (95%CI: 0.92–2.10), respectively. Having a family member with viral hepatitis was also borderline associated (2.09 (95%CI: 0.97–4.50)) with anti-HCV positivity. Conclusions This study found a high-intermediate level of endemicity for HBsAg and a high level of endemicity for anti-HCV antibodies in three large regions of Kazakhstan. We found that history of surgery was not associated with HbsAg neither with anti-HCV seropositivity rates. Blood transfusion was associated with anti-HCV seropositivity, however, to investigate effectiveness of the introduced comprehensive preventive measures in health care settings, there is a need to conduct further epidemiological studies.


2020 ◽  
Author(s):  
Yasser Ahmed Ghaleb ◽  
Aymn Zaid Alshahari ◽  
Majdi Abdullhabeeb Ali ◽  
Mohammed Abdullah Al Amad ◽  
Abdulwahed Abduljabbar Al Serouri

Abstract Background: Yemen is facing major challenges in ensuring the safety and availability of blood transfusion to meet the increased demand for blood transfusion due to the protracted conflict. However, Transfusion-transmissible infectious (TTIs) agents such as hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), syphilis and malaria remain the greatest threats for blood transfusion safety in such fragile, conflict-affected and vulnerable settings. This study aimed to determine the magnitude of TTIs among blood donors attending National Blood Transfusion and Research Center (NBTRC) and its associated factors. Methods: Cross- sectional study was conducted on 340 blood donors at the NBTRC during November and December 2017. Data was collected through face-to-face interview using a predesigned questionnaire that covered socio-demographic characteristics and possible TTIs associated factors. Blood samples were drawn and tested for HBV surface antigen (HBsAg), HCV antibodies, HIV1, 2 by using electrochemi-luminescence immunoassay technique and rapid immunochromato-graphic for screened syphilis and malaria antibodies. Result: The overall prevalence of TTIs was 8.8% where 2.5 %, 1.2%, 0.3%, 1.2%, 3.2% have HBV, HCV, HIV, syphilis and malaria respectively. HBV was significantly associated with history of jaundice and cupping. Furthermore, urethero-vaginal excretion was significantly associated with syphilis while malaria was significantly higher among donors from malaria endemic areas. Nearly three-fourth of donations were from replacement donors who had significantly higher TTIs prevalence than the voluntary donors: 10.4% vs. 3.3%, OR 3.4 (CI: 1.1-11.6). Conclusions: Although the prevalence of TTIs is low, it poses a serious risk for blood recipients especially in in fragile, conflict-affected and vulnerable settings where needs for blood transfusion are increasing and resources are limited. Therefore, using more sensitive screening methods and establishment of TTIs surveillance system should be considered. Efforts should be made to improve donor recruitment procedures and increase the proportion of regular and voluntary donation.


2017 ◽  
Vol 24 (03) ◽  
pp. 370-374
Author(s):  
Muhammad Zahid Latif ◽  
Haroon Riaz ◽  
Syed Waseem Ahmad Mujtaba ◽  
Rahila Nizami

Objectives: This study was conducted to assess the knowledge, attitude andpractices of students regarding blood transfusion in a medical institute. Settings: Azra NaheedMedical College Raiwind road Lahore. Study Design: Descriptive, cross sectional study. StudyPeriod: May and June, 2015. Methods: After the approval of the ethical institutional reviewcommittee, 168 students of 4th year MBBS and 6th semester DPT were included in this study.The data was collected on a structured questionnaire. This data was entered in the version 16of SPSS and analyzed by the use of statistical tools. Results: Out of the total 168 participants,90 (53.6 %) were the students of MBBS, whereas 78 (46.4 %) were the students of DPT. The ageof the respondents ranges between 19 to 28 years. 81 (48-2 %) were male students whereas87 (51.8 %) were females. The results represent that the medical students are having a goodknowledge regarding blood donation but a clear majority of the respondents (63.7 %) havenever donated blood. However a vast majority (78 %) of the participants responded to donateblood in near future. Conclusion: .The blood donation and transfusion is a safe procedure,but it may affect the health of recipient if the necessary measures are not observed. This studyreflects that medical students have good knowledge about blood donation and are willingto donate in near future. A campaign for awareness and motivation regarding voluntary andunpaid blood donation can help to achieve the target of WHO for safe blood transfusion.


2015 ◽  
Vol 8 (4) ◽  
pp. 203 ◽  
Author(s):  
Muhammad Bilal ◽  
Abdul Haseeb ◽  
Ibrahim Zahid ◽  
Sehan Siraj Lashkerwala ◽  
Fawad Saeeduddin ◽  
...  

<p>Introduction<strong>: </strong>Blood donation is necessary in order to maintain an adequate supply of blood to patients who are suffering from any kind of disease or trauma, which requires them to have blood transfusion. Female non-blood donors are generally low in number.<strong> </strong>Therefore, this research was carried out to assess the main reasons behind the lack of blood donations made by females, and their knowledge, attitude and perceptions towards voluntary blood donation.</p> <p>Methodology: A cross-sectional study was conducted on 664 female health professionals, who were selected by non-probability convenience sampling from two tertiary care hospitals. A pretested questionnaire was presented to the sample population, and the data was entered and analyzed on SPSS (V17).</p> <p>Results: 94.6 % were aware with the fact that blood is screened for AIDS, Hepatitis B and C before transfusion. Moreover, 83.7% said that they will only donate blood if a family, relative or friend would need it and similarly 83.4%  suggested that they would donate blood if blood donation camps are arranged in hospital premises. 81.8 % thought that blood donors can contract Hepatitis B after donation where as only 29.5% did not blood due already blood loss in menstrual cycle.<strong></strong></p> <p>Conclusion<strong>: </strong>The participants had adequate knowledge about the benefits of blood donation. The most important reason identified for not donating blood is the lack of facilities within the workplace or lack of approach by responsible authorities. The results of the study may help in minimizing the misconceptions of the participants about blood transfusion, which would increase their contribution towards blood donation.</p>


Author(s):  
Irm Yasmeen ◽  
Ibrar Ahmed ◽  
Shazia Bashir

Background: Blood is the liquid connective tissue composed of cells and plasma. It is the most precious and unique gift that one person gives to another. Blood banks are not the manufacturing factories. It can only be available on replacement basis. Periodic review of blood components usage is essential to assess the blood utilization pattern in hospitals. This study was conducted to analyse the efficiency of blood utilization and to minimize the inappropriate use of blood.Methods: A retrospective cross-sectional study was conducted in the department of blood transfusion and immunohematology, government medical college and associated hospital, Rajouri for a period of one year with effect from November 2019 to November 2020. Data was collected using blood bank record. Blood utilization was calculated using crossmatch to transfusion ratio (C/T), transfusion probability (T%) and transfusion index (TI) indices.Results: A total of 974 patients were requested to prepare 1270 crossmatched units. Of these 1141 blood units were transfused for 664 patients. The total donations during that period were 1197. 998 donors were replacement donors and 199 were voluntary non-remunerated blood donors donated at various blood donation camps. The overall values of C/T, T% and TI were 1.1:1, 68.1% and 1.1 respectively.Conclusions: Blood utilization indices show efficient usage of blood. However, a blood ordering policy (MSBOS) must be developed to guide the clinicians regarding blood usage which can decrease overordering of blood thereby reducing unnecessary usage of reagents, manpower and also wastage of blood due to outdating. 


Sign in / Sign up

Export Citation Format

Share Document