scholarly journals The effect of vaginal evening primrose on the Bishop score of term nulliparous women

2019 ◽  
Author(s):  
Motahareh Najafi1 ◽  
Marzeyeh Loripoor ◽  
Zahra Saghafi ◽  
Majid Kazemi
Keyword(s):  
Intervention Group ◽  
Cervical Ripening ◽  
Bishop Score ◽  
Chi Square ◽  
Double Blind ◽  
Evening Primrose ◽  
Nulliparous Women ◽  
Comprehensive Health ◽  
Chi Square Test ◽  
The Difference

Background & Aim: Desirable bishop score is necessary for having a successful delivery. Prostaglandins are effective on cervical ripening, and primrose contains precursors of these materials. Therefore, the present study was conducted to evaluate the effect of vaginal Evening primrose on the bishop score among term nulliparous women. Methods & Materials: The present double-blind, randomized clinical trial was conducted on 86 nulliparous women who referred to the comprehensive health service centers of Rafsanjan from November 2017 to May 2018. The samples were selected through convenient sampling method and allocated into two intervention and placebo groups with simple random assignment. The intervention group used a daily dose of 1000 mg vaginal capsules of Evening primrose from the 38th week of pregnancy until delivery, and the placebo group received a similar placebo with a similar administration method. The Information about the women’s bishop score was gathered from the participants’ medical files in the hospital and then was analyzed using SPSS software version 16 and Kolmogorov-Smirnov test, Chi-square test, and independent t-test. Results: The total mean and standard deviation of the bishop score in the intervention and placebo groups were respectively 7.83 ± 2.09 and 4.46 ± 2.39, and the simplified bishop score in the intervention and the control groups was respectively 5.93 ± 2.42 and 2.81 ± 2.02. The difference between the two groups considering both of the bishop scores was statistically significant (p = 0.001). Conclusion: Vaginal Evening primrose is useful to ripen the cervix of term nulliparous women, and so, it could be administered for this purpose.

scholarly journals Konseling gizi dan pengaruhnya terhadap asupan zat gizi dan tekanan darah pada pasien hipertensi rawat jalan di Rumah Sakit Umum Daerah Provinsi Sulawesi Tenggara

2009 ◽  
Vol 6 (1) ◽  
pp. 21
Author(s):  
Suwarni Suwarni ◽  
Ahmad Husein Asdie ◽  
Herni Astuti
Keyword(s):  
Blood Pressure ◽  
Intervention Group ◽  
Control Group ◽  
Nutrition Counseling ◽  
Local Hospital ◽  
Chi Square ◽  
Quasi Experimental ◽  
Chi Square Test ◽  
Nutrition Intake ◽  
The Difference

Background : Hypertension is one of the most common worldwide diseases that can be an important public health challenge. The causes of hypertension are high consumption of salt and fat, obesity, stress, age, sex, family history, smoking, and consumption of alcoholic drinks. The prevalence of hypertension in the world, Asia, and Indonesia are 15-20%, 8-18%, and 1,8-28,6%, respectively. The solution to this problem is not only depend on drugs but also counseling through leaflet as the process of assisting clients in facing the problem of hypertension.Objectives : To know the effect of nutrition counseling on nutrition intake and blood pressure of hypertension outpatients at local hospital of the Province of Southeast Sulawesi. Methods : The study was quasi experimental with pre- and post-control design. Samples were divided into 2 groups; intervention group was given nutrition counseling and leaflet and the second (control) was only given leaflet. Samples were hypertension outpatients who fulfilled inclusions and exclusions criteria, and there were 25 samples per group. Data of nutrient intake were processed using Nutrisurvey. Chi-square test was used to identify the difference between the intervention group and the control group; whereas t-test was used to identify independent as well as dependent variables.Results : There were no significant differences in intake of fat, natrium, potassium, and magnesium between the intervention group and control group (p > 0.05); but there were differences between them at the end of study (p < 0.05). Blood pressures of both of them were also not different (p > 0.05); however, at the end of study there was difference between them (p < 0.05).Conclusion : Nutrition counseling could improve nutrition intake and blood pressure of hypertension outpatients at local hospital of the Province of Southeast Sulawesi.

scholarly journals Randomized, double-blind, three-arm, parallel-group study to compare the efficacy and safety of a single dose of 100 and 200 mg of mifepristone for cervical ripening in term pregnancies

2021 ◽  
Vol 10 (2) ◽  
pp. 428
Author(s):  
Leonardo J. Orozco ◽  
Silvia Guerrero ◽  
Mixel J. Rosales ◽  
Jose S. Ramos
Keyword(s):  
Controlled Trial ◽  
Uterine Fibroids ◽  
Cervical Length ◽  
Mean Value ◽  
Cervical Ripening ◽  
Efficacy And Safety ◽  
Chi Square ◽  
Double Blind ◽  
Significant Difference ◽  
Chi Square Test

Background: Mifepristone is an antiprogestin developed to antagonize the action of progesterone by inhibiting its receptors. It has had a recognized role in the medical termination of early pregnancy, reduction in the volume of uterine fibroids and endometriosis symptoms. A new indication for labor induction and cervical ripening in has been proposed. The objective was to compare the efficacy and safety of mifepristone 100 and 200 mg with placebo for cervical ripening in term pregnancies.Methods: Double-blind, placebo-controlled trial of 90 term pregnancy women randomly assigned to receive orally tablet of 100 mg and 200 mg mifepristone or placebo. Efficacy was assessed by measuring changes in cervical ripening according to Bishop 72 hours after treatment. Statistical analysis was using the t-student test and the chi-square test. The relative risk (RR) was determined with a 95% confidence interval.Results: The bishop score and the number of contractions at 48 hours in the group of 200mg of mifepristone presented a significantly higher mean value in relation to the placebo (p=0.04). At 72 hours, cervical length showed a significant difference (p<0.01) in both mifepristone groups compared to the placebo group. Also, at 72 hours a significant increase in the mean duration of contractions was demonstrated in the 100 mg mifepristone group.Conclusions: There was a significant increase in Bishop's score for the 200 mg mifepristone group probably due to a significant increase in contractions at 24 hours. No differences were observed between groups in adverse events.

Effect of chamomile oil on cesarean section pain in primiparous women: a randomized clinical trial

2020 ◽  
Vol 15 ◽  
Author(s):  
Roghayeh Zardosht ◽  
Ameneh Basir ◽  
Amirhossein Sahebkar ◽  
Seyed Ahmad Emami
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Pain Intensity ◽  
Intervention Group ◽  
Control Group ◽  
Post Intervention ◽  
Chi Square ◽  
Double Blind ◽  
The Difference ◽  
Primiparous Women

Background: Pain after cesarean section can turn the pleasant event of childbirth into an unpleasant experience for the mother. Pain relief through non-pharmaceutical methods, such as aromatherapy, could potentially be a useful intervention. In this study, the analgesic effect of chamomile oil was studied. Purpose: The current research was conducted to study the effect of chamomile oil on cesarean section pain in primiparous women. Materials and methods: This was a randomized double blind clinical trial wherein 128 primiparous pregnant women (who willingly selected cesarean section) took part. In the aromatherapy group, the subjects inhaled one drop of 5% chamomile oil, and in the control group the subjects inhaled one placebo drop. In both groups the subjects inhaled for 15-20 minutes at a distance of 5 cm from the nose at 4, 8, and 12 hours after surgery, and pain intensity was measured before and after half an hour after inhalation using the visual analog scale (VAS). For data analysis, the software SPSS (version 25) and descriptive statistics (frequency, frequency percentage, mean, and standard deviation) were used. In order to determine the significance, inferential statistics (Mann-Whitney, Wilcoxon, independent t-test, and Chi-square) were used. Findings: Data indicated that the intervention and placebo groups were homogeneous in terms of demographic variables. The average weights and heights of women in the intervention group were 86/5± 5/9 and 163/7 ±5/1, respectively. Corresponding values women in the control group were 84/5± 5/7 kg and 163/4± 5/8 cm. The finding of the current research indicates that the intervention and placebo groups showed no significant statistical difference in terms of baseline pain before intervention (p=0.08), while the difference between the two groups was significant in terms of pain 4, 8, and 12 hours after intervention (p<0.01). Therefore, inhalation of chamomile oil reduced pain intensity significantly compared to post-intervention. Conclusion: According to the results of the present study, inhalation of chamomile oil following caesarean section in primiparous women reduced pain and also the need for analgesics. Therefore, the use of aromatherapy with chamomile oil as a simple way without any side effects for the reduction of pain in mothers after cesarean section is recommended.

scholarly journals Comparison of the Effect of Vaginal Capsule of Evening Primrose Oil and Misoprostol on Cervical Ripening of Nulliparous Women with Post-term Pregnancy

2019 ◽  
pp. 1-9
Author(s):  
Soma Bahmani ◽  
Kajal Hesamy ◽  
Shola Shahgheibi ◽  
Daem Roshani ◽  
Roonak Shahoei
Keyword(s):  
Intervention Group ◽  
Vital Signs ◽  
Cervical Ripening ◽  
Control Group ◽  
Evening Primrose Oil ◽  
Term Pregnancy ◽  
Evening Primrose ◽  
Uterine Contractions ◽  
Nulliparous Women ◽  
Post Term Pregnancy

Background and Objective: Post-term pregnancy (gestational age of ≥294 days [≥42 weeks] is associated with increased perinatal morbidity and mortality. The present study was conducted to compare the effect of vaginal capsule of evening primrose oil and misoprostol on cervical ripening of nulliparous women with post-term pregnancy. Materials and Methods: This research has been conducted with the one-blind randomized trial method on 130 pregnant women with post-term pregnancy visiting to the labor ward of sanandaj Besat Hospital. Samples were divided into two groups of intervention and control with the randomized allocation method. The intervention group receiving 500 mgvaginal evening primrose capsule and 25 micrograms of sublingual misoprostol, and the control group receiving a placebo-vaginal capsule and 25 micrograms of misoprostol sublingually. Data collecting tools include: demographic specifications questionnaire and Bishop Checklist. Data was analyzed through SPSS software version 21 and by using Chi-square, T-test, covariance analysis, one-way ANOVA, and repeated measures. P <0.05 was considered significant. Results: The results showed that the mean Bishope scores of the subjects in the intervention group were significantly higher than the control group (p <0.05). There was no significant difference in uterine contractions, fetal heart rate and vital signs between two groups (p> 0.05). Conclusion: The results of the present study showed that vaginal capsule of evening primrose oil is effective on the rate of cervical ripening in post-term pregnancies. Also, no significant effect on was observed on fetal heart rate, uterine contractions, and vital signs of the mother.

scholarly journals A Randomized, Controlled, Parallel-Group, Trial on the Effects of Melatonin on Fatigue Associated with Breast Cancer and Its Adjuvant Treatments

2021 ◽  
Vol 20 ◽  
pp. 153473542098834
Author(s):  
Abdolazim Sedighi Pashaki ◽  
Kamal Mohammadian ◽  
Saeid Afshar ◽  
Mohammad Hadi Gholami ◽  
Abbas Moradi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Intervention Group ◽  
Chi Square ◽  
Significance Level ◽  
Severe Fatigue ◽  
Before And After ◽  
Brief Fatigue Inventory ◽  
Chi Square Test ◽  
Student’S T

Objective: Fatigue associated with malignant conditions and their treatments is a disabling condition. This trial assessed the anti-fatigue effects of melatonin coadministration during adjuvant treatment of patients with the breast cancer. Material and Methods: Patients with breast cancer were randomly assigned to receive melatonin or placebo during adjuvant chemotherapy and radiotherapy. Thirty-seven patients were randomly enrolled in each group. The mean ages of patients in the intervention and control groups were 50.47 ± 10.79 and 46.05 ± 10.55 years, respectively ( P = .223). The intervention group received oral melatonin (18 mg/day) from 1 week before until 1 month after the adjuvant radiotherapy. The level of fatigue was assessed before and after intervention using Brief Fatigue Inventory (BFI) in both groups. To analyze data, the Student’s t-test and the Chi-square test were used at a significance level of P ≤ .05. Results: The BFI score was similar before the intervention in both groups, however, after the intervention, it was significantly lower in the melatonin group ( P < .001). Moreover, the frequency of severe fatigue in the melatonin group was significantly lower than in the placebo group after intervention (42.1% vs 83.3%, P < .001). Conclusion: Coadministration of melatonin during adjuvant chemotherapy and radiotherapy of women with breast cancer decreased the levels of fatigue associated with the malignant condition and its treatments.

The effect of practicing yoga during pregnancy on labor stages length, anxiety and pain: a randomized controlled trial

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Ellahe Mohyadin ◽  
Zohreh Ghorashi ◽  
Zahra Molamomanaei
Keyword(s):  
Controlled Trial ◽  
Intervention Group ◽  
Total Duration ◽  
Measurement Data ◽  
Labor Pain ◽  
Control Group ◽  
Chi Square ◽  
Nulliparous Women ◽  
Two Stages ◽  
And Control

AbstractBackgroundAnxiety and fear of labor pain has led to elevated cesarean section rate in some countries. This study was conducted to investigate the effect of yoga in pregnancy on anxiety, labor pain and length of labor stages.MethodsThis clinical trial study was performed on 84 nulliparous women who were at least 18 years old and were randomly divided into two groups of yoga and control groups. Pregnancy Yoga Program consisting of 6 60-min training sessions was started every 2 weeks from week 26 of pregnancy and continued until 37 weeks of gestation. Anxiety severity at maternal admission to labor was measured by the Spielbergers State-Trait Anxiety Inventory, and labor pain was measured by Visual Analogue Scale (VAS) at dilatation (4–5 cm) and 2 h after the first measurement. Data were analyzed using Chi-Square and t-test.ResultsIntervention group reported less pain at dilatation (4–5 cm) (p=0.001) and 2 h after the first measurement (p=0.001) than the control group. Stat anxiety was also lower in intervention group than the control group (p=0.003) at the entrance to labor room. Subjects in the control group required more induction compared to intervention group (p=0.003). Women in intervention group experienced shorter duration of the first phase of the labor than the control group (p=0.002). Also, the total duration of two stages of labor was shorter in intervention group than the control group (p=0.003).ConclusionsPracticing yoga during pregnancy may reduce women’s anxiety during labor; shorten labor stages, and lower labor pain.

Performance of Abbreviated Protocols Versus Unenhanced MRI in Detecting Occult Breast Lesions of Mammography in Patients with Dense Breasts

2021 ◽  
Author(s):  
Suhong Zhao ◽  
Peipei Chen ◽  
Guangrui Shao ◽  
Baijie Li ◽  
Huikun Zhang ◽  
...  
Keyword(s):  
Reading Time ◽  
Area Under The Curve ◽  
Lesion Size ◽  
Lower Sensitivity ◽  
Chi Square ◽  
Dense Breast Tissue ◽  
Negative Findings ◽  
Chi Square Test ◽  
The Difference ◽  
Sensitivity Specificity

Abstract Objective: To assess the diagnostic ability of abbreviated protocols of MRI (AP-MRI) compared with unenhanced MRI (UE-MRI) in mammographically occult cancers in patients with dense breast tissue.Materials and Methods: The retrospective analysis consisted of 102 patients without positive findings on mammography who received preoperative MRI full diagnostic protocols (FDP) between January 2015 and December 2018. Two breast radiologists read the UE, AP, and FDP. The interpretation times were recorded. The comparisons of the sensitivity, specificity and area under the curve of each MRI protocol, and the sensitivity of these protocols in each subgroup of different size tumors used the Chi-square test. The paired sample t-test was used for evaluating the difference of reading time of the three protocols.Results: Among 102 women, there were 68 cancers and two benign lesions in 64 patients and 38 patients had benign or negative findings. Both readers found the sensitivity and specificity of AP and UE-MRI were similar (p>0.05), whereas compared with FDP, UE had lower sensitivity (Reader 1/Reader 2: p=0.023, 0.004). For different lesion size groups, one of the readers found that AP and FDP had higher sensitivities than UE-MRI for detecting the lesions ≤10 mm in diameter (p=0.041, p=0.023). Compared with FDP, the average reading time of UE-MRI and AP was remarkably reduced (p < 0.001).Conclusion: AP-MRI had more advantages than UE-MRI to detect mammographically occult cancers, especially for breast tumors ≤10 mm in diameter.

Abstract 14721: Impact of Covid-19 on Cardiology Consultation in Tertiary Care Hospital of a Developing Country

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
ghufran adnan ◽  
Osman Faheem ◽  
Maria Khan ◽  
Pirbhat Shams ◽  
Jamshed Ali
Keyword(s):  
Emergency Department ◽  
Tertiary Care ◽  
Reduction Rate ◽  
Care Hospital ◽  
Chi Square ◽  
Coronary Syndrome ◽  
Significant Difference ◽  
Drastic Increase ◽  
Chi Square Test ◽  
The Difference

Introduction: COVID-19 pandemic has overwhelmed the healthcare system of Pakistan. There has been observation regarding changes in pattern of patient presentation to emergency department (ED) for all diseases particularly cardiovascular. The aim of the study is to investigate these changes in cardiology consultations and compare pre-COVID-19 and COVID-19 era. Hypothesis: There is a significant difference in cardiology consultations during COVID era as compared to non-COVID era. Method: We collected data retrospectively of consecutive patients who visited emergency department (ED) during March-April 2019 (non-COVID era) and March-April 2020 (COVID era). Comparison has been made to quantify the differences in clinical characteristics, locality, admission, type, number, and reason of Cardiology consults generated. Results: We calculated the difference of 1351 patients between COVID and non-COVID era in terms of cardiology consults generated from Emergency department, using Chi-square test. Out of which 880 (59%) are male with mean age of 61(SD=15). Analysis shows pronounced augmentation in number of comorbidities [Hypertension(6%), Chronic kidney disease (6%), Diabetes (5%)] but there was 36% drop in total cardiology consultations and 43% reduction rate in patient’s ED visit from other cities during COVID era. There was 60% decrease in acute coronary syndrome presentation in COVID era, but fortuitously drastic increase (30%) in type II myocardial injury has been noted. Conclusion: There is a remarkable decline observed in patients presenting with cardiac manifestations during COVID era. Lack in timely care could have a pernicious impact on outcomes, global health care organizations should issue directions to adopt telemedicine services in underprivileged areas to provide timely care to cardiac patients.

scholarly journals Efficacy of 4% chlorhexidine in preventing neonatal umbilical cord infection

2020 ◽  
Vol 14 (03) ◽  
pp. 136-139
Author(s):  
Fouzia Ishaq ◽  
Anila Jamil ◽  
Muhammad Sajjad ◽  
Maria Iftikhar ◽  
Muhammad Adnan Zafar ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Analytical Study ◽  
Bacterial Colonization ◽  
Neonatal Morbidity ◽  
Chi Square ◽  
Once Daily ◽  
Group 4 ◽  
Chi Square Test ◽  
The Difference ◽  
Random Method

Background: Umbilical cord stump is a budding point for bacterial colonization subsequently leading to sepsis that contributes to high neonatal morbidity and mortality, if not properly managed. Antiseptic care can significantly reduce omphalitis and ultimately improve newborn survival. Objective of this study was to see the efficacy of 4% chlorhexidine use to prevent umbilical cord infection in neonates.Subjects and methods: It was a comparative analytical study conducted in Neonatal unit, Sir Ganga Ram Hospital (SGRH) Lahore from July, 2016 till January, 2017. One hundred neonates were enrolled and randomized into two equal group by simple random method (50 each). In one group, nothing was applied to cord while in chlorhexidine group, 4% chlorhexidine gel was applied on umbilicus and around it, once daily for 7 days or till cord detached whichever came early. First application was done by a nurse followed by duly trained mother/caregiver. The signs of omphalitis (redness, pus or localized oedema) were observed and recorded for each neonate in both groups. Chi square test was used to see the difference in omphalitis in these groups with p˂ 0.05 considered as statistically significant result.Results: Out of 100 neonates, 29 (58%) and 23 (46%) males while 21 (42%) and 27 (54%) females neonates belonged to dry care and chlorhexidine group respectively. Nineteen (38%) neonates with dry cord had omphalitis compared to only 5 (10%) in chlorhexidine group (p 0.001). Neonates with chlorhexidine application showed prolonged mean cord separation time (7.9±1.5 days) compared to dry care (6.1±1.8 days). Conclusion: The use of 4% Chlorhexidine was effective to lower omphalitis compared to neonates with dry cord care.

scholarly journals CONTROL OF POST-SURGICAL PAIN

2010 ◽  
Vol 17 (03) ◽  
pp. 400-404
Author(s):  
ALI MIR MANSOURI ◽  
FARNOUSH FARZI ◽  
SHIRIN KHALKHALIRAD ◽  
Katayoon Haryalchi ◽  
Abas Sediginejad
Keyword(s):  
Pain Relief ◽  
Cesarean Section ◽  
Pain Control ◽  
Nausea And Vomiting ◽  
Chi Square ◽  
Double Blind ◽  
Analgesic Effects ◽  
Emergency Cesarean ◽  
Surgical Pain ◽  
Chi Square Test

Introduction: There are many complications for patients with post cesarean section relative pain. So it delays in discharging or increasing in hospital stay. The objective of this study was a comparison between Tramadol and Meperidine according to pain relief or other possible complications in post cesarean section pain control. Materials and Methods: This study was a double blind clinical trial. It arranged for 240 parturients who scheduled for emergency cesarean section with pain after surgery in spite of spinal anesthesia. All patients were in ASA class I. They were divided randomly in two groups .Meperidine (M) and Tramadol (T) groups with 120 patients in each group. After beginning of pain in post anesthesia care unit (VAS> or = 4), in group (T) tramadol 1.5 mg/kg and in group (M) meperidine  .5 mg/kg were injected intravenously. Apart from pain, other drug complications such as shivering, blood pressure changes, itching, nausea and vomiting, drowsiness were recorded one and two hours after injection. Data were analyzed by chi-square test. Results: Relative frequency rate (RFR) of 50% decrease in pain score one hour after intravenous injection was 56.7% in group (T) and 69.2% in group (M) ( P = 0.054). RFR for respiratory depression after one hour was 5.8% in (M) group and 0 in (T) group (P = 0.007). RFR for nausea after one hour was 39.2% in (T) group and 23.3% in (M) group (P = 0.008). RFR for vomiting after one hour was 23.3% in (T) group and 13.3% in (M) group (P= 0.045). RFR for drowsiness after one hour was 25% in (M) group and 3.3% in (T) group (P=0.007). There was no statistically significant relationship after 2nd hour for pain relief, nausea, vomiting and drowsiness between two groups. There was no difference between two groups in RFR for shivering, blood pressurechanges and itching in both two groups. Conclusion: This study illustrates both remedies Meperidine and Tramadol which were effective for pain relief and shivering after cesarean section. But according to high incidence of nausea and vomiting with Tramadol and more analgesic effects of Meperidine than Tramadol, administration of Meperidine is better than Tramadol after cesarean section for pain control.

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