scholarly journals Diastolic function left ventricle in a debut of revealing of hypertonic illness at young age

2007 ◽  
Vol 13 (4) ◽  
pp. 292-294
Author(s):  
V. V. Kuznetsova ◽  
A. V. Bursikov
Keyword(s):  
Left Ventricle ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Doppler Echocardiography ◽  
High Speed ◽  
Young Age ◽  
Left Auricle ◽  
Functional Remodeling ◽  
Peak Speed

The purpose: To estimate diastolic function left ventricle at persons of young age with recently revealed arterial hypertension and to reveal early attributes of its infringement. Materials and methods: On device LOGIQ 500 method Doppler echocardiography studies diastolic function left ventricle at 34 patients of young age with prescription of revealing arterial hypertension no more than 3 years and practically healthy 48 persons. Results: At an arterial hypertension already in a debut of revealing of disease change of some Doppler echocardiography parameters diastolic fillings left ventricle takes place: decrease in high-speed parameters early diastolic fillings and increase in peak speed and fraction of late filling left ventricle, that reflects difficulty of filling left ventricle and increased hemodinamic loading on the left auricle. The conclusion: Changes of speeds diastolic fillings left ventricle reflects its structurally functional remodeling and can be used as criterion of diagnostics of defeat of heart at arterial hypertension

scholarly journals Features of structural and functional remodeling of the left ventricle in patients suffering from arterial hypertension with concomitant hypothyroidism

2019 ◽  
Vol 26 (5) ◽  
pp. 43-52
Author(s):  
V. I. Tseluyko ◽  
L. M. Yakovleva ◽  
D. A. Korchagina
Keyword(s):  
Body Mass Index ◽  
Left Ventricle ◽  
Arterial Hypertension ◽  
Diastolic Dysfunction ◽  
Body Mass ◽  
Mean Value ◽  
Left Ventricular ◽  
Control Group ◽  
Functional Remodeling ◽  
The Mean

The aim – to study the features of structural and functional remodeling of the left ventricle in patients suffering from arterial hypertension with concomitant hypothyroidism and to determine clinical and past medical history and laboratory factors associated with their development. Materials and methods. 50 patients suffering from hypertension with concomitant hypothyroidism were enrolled into the study. Depending on the level of thyroid stimulating hormone in the serum the examined patients were distributed into two groups of 25 patients with the compensated and 25 with decompensated course of hypothyroidism. The control group consisted of 30 patients with hypertension in which the pathology of the thyroid gland was excluded. The comparison of the main parameters of the echocardiography study of the myocardium has been performed depending on hypothyroidism compensation. Assessment of parameters of transmitral diastolic blood flow has been performed. A regression analysis has been conducted to detect the relation of clinical and past medical history factors and echocardiographic parameters with the development of diastolic dysfunction by E/A ratio. The values of central hemodynamics have been studied for evaluation of the contractile function of the myocardium. Results and discussion. According to the results of the echocardiography of both examined groups it has been found that the final systolic and stroke volume exceeded the parameters of the control group. The mean value of the left ventricle ejection fraction was statistically significantly lower than in the control group (p=0.004). The left ventricle myocardial mass in patients with hypothyroidism was statistically significantly greater than in the control group. It was proved that in patients, who were diagnosed with decompensated hypothyroidism, the mean value of the left atrium size to growth by the degree of 2.7 was statistically significantly higher than in the control group (p=0.01), whereas the average value of the ratio of the size of the left atrium to the surface area of the body had no statistically significant differences between the groups. It has been found that in both groups the proportion of patients with diastolic dysfunction in which the E/A ratio was less than 1.0 was higher than in the control group (р=0.01 and p=0.03, respectively). The independent factors of diastolic dysfunction of the left ventricle in patients with hypertension in the presence of hypothyroidism have been found. Conclusions. In the presence of decompensated hypothyroidism in patients with arterial hypertension, both with obesity and with normal body mass index, left ventricular mass indexes were significantly higher in comparison with a control group. Regardless of the compensation of the thyroid state in patients with arterial hypertension, the ejection fraction was significantly lower. According to regression analysis, independent factors for the development of diastolic dysfunction in patients with arterial hypertension and hypothyroidism with a body mass index ≥ 30 kg/m2 is the index of mass of the left ventricular myocardium, determined by the degree of 2.7, the level of total cholesterol to statistical significance – the level of office systolic blood pressure and the duration of hormone replacement therapy for hypothyroidism; with body mass index < 30 kg/m2 – age and left atrial index, determined by body surface area. For patients with arterial hypertension and reduced thyroid gland function, violation of the left ventricular myocardial relaxation is typical as evidenced by a higher proportion of patients with a decrease in E/A to less than 0.8 in these patients.

scholarly journals Аrterial stiffness and diastolic function of the left ventricle in patients with arterial hypertension and frailty

2021 ◽  
pp. 118-123
Author(s):  
E. S. Fomina ◽  
V. S. Nikiforov
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Left Ventricle ◽  
Arterial Hypertension ◽  
Systolic Blood Pressure ◽  
Diastolic Function ◽  
Pulse Pressure ◽  
Filling Pressure ◽  
Left Shoulder ◽  
Average Blood Pressure

Introduction. Increased arterial stiffness is one of the key links in the formation of cardiovascular pathology in older age groups. At the same time, the effect of vascular stiffness on myocardial function in cardiac patients with frailty remains insufficiently studied.Aim of study. Тo analyze the data of arterial stiffness and diastolic function of left ventricle (LV) in patients older than 65 years with arterial hypertension and frailty.Materials and methods. The study included 90 outpatient and inpatient patients older than 65 years with the presence of arterial hypertension. All patients were divided into two groups: with the presence and absence of frailty. To identify frailty, we used the questionnaire “Age is not a hindrance”, a short battery of physical activity tests. Methods of volumetric sphygmometry, echocardiography, including tissue Doppler were used. The obtained data were analyzed using a package of statistical programs.Results. The results of a comparative simultaneous non-randomized descriptive study of two groups of patients are presented. The study found that the systolic function, diastolic dysfunction of the left ventricle by the type of slowing down of LV relaxation in both groups did not significantly differ in their indicators. In the group of patients with frailty, LV diastolic dysfunction was significantly more often detected by the type of pseudonormalization – with an increase in filling pressure. When analyzing data of arterial stiffness, differences were obtained in both groups in the left cardio-ankle vascular index (LCAVI), systolic blood pressure (LB SAD), pulse pressure (LB PD) in the left shoulder area, and the delta of average blood pressure in the left ankle area (LA% IDA), which were significantly higher in patients with frailty.Conclusion. In the group of patients with hypertension older than 65 years with frailty, a violation of the LV diastolic function by the  type of  pseudonormalization with an increase in  filling pressure prevails. An increase in  filling pressure in  the  group of patients older than 65 years with hypertension and the presence of frailty is associated with an increase in the complex of indicators characterizing arterial stiffness – the cardio-ankle vascular index, systolic blood pressure, pulse pressure in the left shoulder area, the delta of average blood pressure in the left ankle area.

scholarly journals IMPACT OF SUBCLINICAL PRIMARY HYPERPARATHYROIDISM ON CARDIOVASCULAR MANIFESTATIONS OF ESSENTIAL ARTERIAL HYPERTENSION

2012 ◽  
Vol 67 (11) ◽  
pp. 53-58
Author(s):  
B. G. Iskenderov ◽  
O. N. Sisina
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Hormone Level ◽  
Left Ventricular ◽  
Parathyroid Hormone Level ◽  
Functional Remodeling ◽  
Essential Arterial Hypertension ◽  
Artery Remodeling

At 95 patients with essential arterial hypertension features of structural and functional remodeling of left ventricular and humeral artery depending on a level parathyroid hormone in blood are studied. It is shown that while increasing of plasma parathyroid hormone level frequency and expressiveness of left ventricular and humeral artery remodeling increases whereas diastolic function and endothelium-dependent vasodilatation considerably decrease. Subclinical primary hyperparathyroidism in patients with essential arterial hypertension is detected in 22,1% of cases. 

Diastolic function of the right ventricle in workers of coal mining enterprises in the South of Kuzbass

2021 ◽  
Vol 61 (6) ◽  
pp. 371-378
Author(s):  
Olga Yu. Korotenko ◽  
Egor S. Filimonov ◽  
Nikolay I. Panev ◽  
Evgeniya V. Ulanova
Keyword(s):  
Left Ventricle ◽  
Right Ventricle ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Work Experience ◽  
Open Pit ◽  
The South ◽  
Open Pit Mines ◽  
Right Ventricular Diastolic Function ◽  
The Right

Introduction. Diastolic function is characterized by the earliest changes in the ventricular myocardium, rather than violations of their contractility, and can be used in the algorithm of prophylactic measures to prevent fatal cardiovascular events, including in people working at industrial enterprises. The objective of the study was to assess the indices of diastolic function of the right ventricle in workers of the coal mining industry in the South of Kuzbass. Materials and methods. Under the conditions of a periodic medical examination, we surveyed 337 people without lung diseases and coronary heart disease, of which 206 workers of coal mines in the South of Kuzbass and 131 workers of open pit mines, aged from 40 to 55 years (the average age of the miners was 46.12±0.36 years old, of the workers at open pit mines was 46.98±0.34 years, p=0.107). On the ultrasound system "Vivid E9" manufactured by General Electric, all examined persons underwent an assessment of the structural and functional state of the heart. Results. Diastolic dysfunction in the form of a decrease in the ratio of transtricuspid flows less than one was revealed in 22.5% of the miners with arterial hypertension and in 2.6% of the subjects without it (p=0.00001), in the workers of open pit mines there was in 12.3% and 8.3%, respectively (p=0.071). A decrease in the ratio of tissue Doppler flows of tricuspid annulus plane movement was detected in 89.9% of the miners with arterial hypertension and in 81.2% of the subjects without it (p=0.083), this parameter also did not differ among the workers of open pit mines (68.4% and 60.3% respectively, p=0.337), but the differences between the miners and the workers of the open pit mines turned out to be reliable (p=0.0012 in those examined with arterial hypertension, p=0.0015 - without it). Based on the conducted correlation analysis, it was revealed that the development of impaired right ventricular diastolic function in coal industry workers was influenced not only by generally accepted factors and concomitant arterial hypertension, but also by long-term work experience in underground conditions in the miners. Conclusion. The development of diastolic dysfunction of the right ventricle in miners was influenced by work experience in underground working conditions, the presence of arterial hypertension, a decrease in the longitudinal deformation of the left ventricle, a decline in the vital capacity of the lungs and impaired diastolic function of the left ventricle. Associations of right ventricular diastolic function indices with the presence of arterial hypertension, increased values of the smoker’s index, Quetelet index, waist circumference, relative wall thickness index of the left ventricle, a decrease in the longitudinal deformation of the left ventricle and forced expiratory volume in 1 second and impaired diastolic function of the left ventricle were revealed in the workers of open pit mines.

Factors associated with left ventricle diastolic function impairment in patients with moderate arterial hypertension

2016 ◽  
Vol 10 (4) ◽  
pp. e53
Author(s):  
Olena Torbas ◽  
Yuriy Sirenko ◽  
Svitlana Kushnir ◽  
Oksana Rekovets ◽  
Vladimdir Granich ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Factors Associated ◽  
Function Impairment

Myocardial deformation and parameters of diastolic function of the left ventricle in workers of coal mining enterprises in the South of Kuzbass with arterial hypertension

2020 ◽  
pp. 151-156
Author(s):  
O. Yu. Korotenko ◽  
E. S. Filimonov
Keyword(s):  
Blood Pressure ◽  
Left Ventricle ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Left Ventricular ◽  
Coal Industry ◽  
Myocardial Deformation ◽  
Longitudinal Deformation ◽  
The South ◽  
Coal Miners

Introduction. Long-term persistent hypertension can lead to heart failure. The study of its early markers, which include diastolic dysfunction of the left ventricle and reduction of longitudinal myocardial deformation, is of importance for workers engaged in harmful and dangerous working conditions.The aim of the study is to evaluate the parameters of myocardial deformation and diastolic function of the left ventricle, as well as their interrelation with arterial hypertension in workers of the coal mining industry in the South of Kuzbass.Materials and methods. 384 people were examined (men), including 266 workers of coal mines in the South of Kuzbass (drifters, stope miners, operators of rock removing machines) and 118 persons who were not employed in the coal industry, aged from 40 to 55 years. Arterial hypertension was detected according to the clinical recommendations for the diagnosis and treatment of arterial hypertension in 2019. The structural and functional state of the heart was studied by echocardiography with evaluation of the longitudinal deformation of the left ventricle by 2D-strain method and its diastolic function using pulse-wave and tissue dopplerography.Results. The prevalence of persons with arterial hypertension in the group of workers employed in the coal industry was established: 43.2% against 26.3% in the comparison group (p=0.002). Longitudinal deformation of the left ventricular myocardium in all subjects was significantly less in the presence of high blood pressure: -21.0±0.18 vs. -19.2±0.22% (p<0.001) in the main group and -21.54±0.22 vs. -19.84±0.38% (p<0.001) in the comparison group. It should also be noted that there is a tendency to differ in subgroups of subjects without arterial hypertension towards a greater reduction in longitudinal myocardial deformation in coal miners (-21.54±0.22 and -21.0±0.18%, p=0.062). In miners, diastolic left ventricular dysfunction was significantly more common than in the group without occupational hazards: 52.5 and 39.3%, respectively, p=0.021. Its presence in the cohort of coal miners with arterial hypertension was detected significantly more often (58.9%) than in individuals with normal blood pressure (25.9%), p<0.0001. In turn, in the group of people not employed in the coal industry, diastolic dysfunction of the left ventricle was also more common in the presence of arterial hypertension: in 42.6 and 13.9% of cases, respectively (p<0.001).Conclusions. The incidence of arterial hypertension among coal miners was significantly higher than in people who do not work at coal mining enterprises. In all patients with arterial hypertension, the longitudinal deformation of the left ventricular myocardium with the preserved ejection fraction was lower than in those with normal blood pressure. Diastolic myocardial dysfunction of the left ventricle was significantly more common among those examined with underground working conditions, especially in the group of people with arterial hypertension.The authors declare no conflict of interests.

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