scholarly journals Investigations into Foot and Mouth Disease Outbreak among Small Ruminants in Karnataka State of India

2021 ◽  
Author(s):  
Raveendra Hegde ◽  
B.P. Shivashankar ◽  
N. Gautham ◽  
G.R. Praveenkumar ◽  
B. Rajasekar ◽  
...  
Keyword(s):  
Multiplex Pcr ◽  
Small Ruminants ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Perivascular Spaces ◽  
Grazing Land ◽  
Sheep Population ◽  
Goat Population ◽  
Karnataka State ◽  
Foot And Mouth

Background: Foot-and-Mouth Disease (FMD) remains a serious threat to the Indian livestock sector due to significant economic loss associated with it. Systematic vaccination of large ruminants over the years has lead to a gradual reduction in the number of disease outbreaks in India. However exposure to FMDV infection in small ruminants has been recorded during the past few years (Rout et al. 2013). Sheep and goat population have not been vaccinated so far against FMD under the FMD-Control program (FMD-CP). The present study highlighted the outbreak of FMD in small ruminants in Karnataka, India.Methods: During the period 2018-19, seven suspected FMD outbreaks among sheep population in Bellary and Tumakuru districts of Karnataka state were investigated. Tongue epithelium (oral swabs) and foot lesions (n=23) from clinically affected sheep and tissues such as heart, lung, liver, spleen, lymph nodes and kidneys from lambs during post mortem (n=67) were collected. All the samples were processed in the laboratory for the detection of FMD virus antigen by employing Serotype differentiating antigen detection ELISA and by multiplex PCR. Heart tissue samples were also collected in buffered formalin for histopathology study and processed by routine paraffin embedding technique and stained with Hematoxylin and Eosin (H and E). Serum samples from the recovered animals were collected and screened by NSP-ELISA and LPB-ELISA to check the antibody status in the affected herd. Result: A total of seven suspected outbreaks of FMD involving 688 small ruminants was investigated. The outbreak of FMD due to FMDV serotype O was confirmed by ELISA and multiplex PCR assays. Clinically, the affected adult sheep showed typical signs of FMD, while mortality in young lambs was observed without apparent signs of disease. Histologically, heart tissues from FMD affected lambs showed myocardial necrosis with marked aggregations of lymphocytes and neutrophils in the myocardium and perivascular spaces. History of FMD outbreaks in cattle and common grazing land for the livestock, as well as sheep within the reach of these villages, may be the major contributing factors for the outbreaks in sheep populations.

Farm Community Impacts of Foot-and-Mouth Disease Outbreaks in Cattle and Buffaloes in Karnataka State, India

2015 ◽  
Vol 64 (3) ◽  
pp. 849-860 ◽  
Author(s):  
G. Govindaraj ◽  
B. Ganeshkumar ◽  
K. R. Nethrayini ◽  
R. Shalini ◽  
V. Balamurugan ◽  
...  
Keyword(s):  
Disease Outbreaks ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Karnataka State ◽  
Foot And Mouth ◽  
Community Impacts ◽  
Farm Community

scholarly journals Epidemiology of foot and mouth disease in Karnataka state, India: a retrospective study

VirusDisease ◽  
2014 ◽  
Vol 25 (4) ◽  
pp. 504-509 ◽  
Author(s):  
Raveendra Hegde ◽  
Amitha R. Gomes ◽  
P. Giridhar ◽  
Srikanth Kowalli ◽  
B. P. Shivashankar ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Karnataka State ◽  
Foot And Mouth

scholarly journals Epidemiological study on foot-and-mouth disease in small ruminants: sero-prevalence and risk factor assessment in Kenya

2020 ◽  
Author(s):  
Eunice C. Chepkwony ◽  
George C. Gitao ◽  
Gerald M. Muchemi ◽  
Abraham K. Sangula ◽  
Salome W. Kairu-Wanyoike
Keyword(s):  
Risk Factors ◽  
Virus Transmission ◽  
Small Ruminants ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Cluster Sampling ◽  
Serum Samples ◽  
Cross Sectional ◽  
Production Type ◽  
Foot And Mouth

AbstractFoot-and-mouth disease (FMD) is endemic in Kenya affecting cloven-hoofed ruminants. The epidemiology of the disease in small ruminants (SR) is not documented. We carried out a cross-sectional study, the first in Kenya, to estimate the sero-prevalence of FMD in SR and the associated risk factors nationally. Selection of animals to be sampled used a multistage cluster sampling approach. Serum samples totaling 7564 were screened for FMD antibodies of Non-Structural-Proteins using ID Screen® NSP Competition ELISA kit. Data were analysed using Statistical Package for Social Studies Version 20. To identify the risk factors, chi-square and logistic regression analyses were used. The country animal level sero-prevalence was 23.3% (95% CI: 22.3-24.3%) while herd level sero-prevalence was 77.6% (95% CI: 73.9-80.9%). Sero-positivity was significantly higher in the pastoral zone (31.5%) than in the sedentary zone at 14.5% (χ2 =303.2, p<0.05). In the most parsimonious backward fitting logistic multivariable regression, the only risk factors that were significantly positively associated with FMD sero-positivity in SR were multipurpose (OR=1.150; p=0.034) and dairy production types (OR=2.029; p=0.003). Those that were significantly negatively associated with FMD sero-positivity were male sex (OR=0.856; p=0.026), young age (OR=0.601; p=0.037), sedentary production zone (OR=0.471; p<0.001), bringing in of SR (OR=0.838; p=0.004), purchase of SR from market/middlemen (OR=0.877; p=0.049), no interaction with wildlife (OR=0.657; p<0.001), mixed production type (OR=0.701; p=0.016), enclosure of SR day and night (OR=0.515; p=0.001), migratory grazing system (OR=0.807; p=0.047), on-farm watering system (OR=0.724; p=0.002), male-from-another-farm (OR=0.723; p=0.030) and artificial insemination (OR=0.357; p=0.008) breeding methods.This study showed that there is widespread undetected virus circulation in SR indicated by ubiquitous spatial distribution of significant FMD sero-positivity in the country. The risk factors were mainly husbandry related. Strengthening of risk-based FMD surveillance in carrier SR which pose potential risk of virus transmission to other susceptible species is recommended. Adjustment of husbandry practices to control FMD in SR and in-contact species is suggested. Cross-transmission and more risk factors need to be researched.

scholarly journals Epidemiological study on foot-and-mouth disease in small ruminants: Sero-prevalence and risk factor assessment in Kenya

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0234286
Author(s):  
Eunice C. Chepkwony ◽  
George C. Gitao ◽  
Gerald M. Muchemi ◽  
Abraham K. Sangula ◽  
Salome W. Kairu-Wanyoike
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Random Effect ◽  
Small Ruminants ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
Production Type ◽  
Foot And Mouth

Foot-and-mouth disease (FMD) is endemic in Kenya affecting cloven-hoofed ruminants. The epidemiology of the disease in small ruminants (SR) in Kenya is not documented. We carried out a cross-sectional study, the first in Kenya, to estimate the sero-prevalence of FMD in SR and the associated risk factors nationally. Selection of animals to be sampled used a multistage cluster sampling approach. Serum samples totaling 7564 were screened for FMD antibodies of non-structural-proteins using ID Screen® NSP Competition ELISA kit. To identify the risk factors, generalized linear mixed effects (GLMM) logistic regression analysis with county and villages as random effect variables was used. The country animal level sero-prevalence was 22.5% (95% CI: 22.3%-24.3%) while herd level sero-prevalence was 77.6% (95% CI: 73.9%-80.9%). The risk factor that was significantly positively associated with FMD sero-positivity in SR was multipurpose production type (OR = 1.307; p = 0.042). The risk factors that were significantly negatively associated with FMD sero-positivity were male sex (OR = 0.796; p = 0.007), young age (OR = 0.470; p = 0.010), and sedentary production zone (OR = 0.324; p<0.001). There were no statistically significant intra class correlations among the random effect variables but interactions between age and sex variables among the studied animals were statistically significant (p = 0.019). This study showed that there may be widespread undetected virus circulation in SR indicated by the near ubiquitous spatial distribution of significant FMD sero-positivity in the country. Strengthening of risk-based FMD surveillance in small ruminants is recommended. Adjustment of husbandry practices to control FMD in SR and in-contact species is suggested. Cross-transmission of FMD and more risk factors need to be researched.

scholarly journals Diagnosis and Control of Foot and Mouth Disease (FMD) in Dairy Small Ruminants; Sheep and Goats

2018 ◽  
Vol 14 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Mohamed Abd El-Fatah Mahmoud ◽  
Alaa Abdelmoneam Ghazy ◽  
Raafat Mohamed Shaapan
Keyword(s):  
Small Ruminants ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Sheep And Goats ◽  
Foot And Mouth ◽  
And Control

Rapid detection of hand, foot and mouth disease enterovirus genotypes by multiplex PCR

2018 ◽  
Vol 258 ◽  
pp. 7-12 ◽  
Author(s):  
Min Wang ◽  
Qian Ren ◽  
Zhenjie Zhang ◽  
Lehai Zhang ◽  
Michael J. Carr ◽  
...  
Keyword(s):  
Multiplex Pcr ◽  
Rapid Detection ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Foot And Mouth

scholarly journals The Implications of EU Regulation 2016/429 on Neglected Diseases of Small Ruminants including Contagious Agalactia with Particular Reference to Italy

Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 900
Author(s):  
Guido Ruggero Loria ◽  
Luigi Ruocco ◽  
Gabriele Ciaccio ◽  
Francesco Iovino ◽  
Robin A. J. Nicholas ◽  
...  
Keyword(s):  
Animal Health ◽  
Small Ruminants ◽  
Foot And Mouth Disease ◽  
African Swine Fever ◽  
Mouth Disease ◽  
Neglected Diseases ◽  
The European Union ◽  
Animal Diseases ◽  
Foot And Mouth ◽  
The Eu

After almost 40 years, the 27 member states (MS) of the European Union (EU) will comply with the European Law 429/2016 in 2021 by completing a process of unification and harmonization of all regulations related to animal health between MS. These new provisions are based on modern scientific principles on animal health, on long-term epidemiological data, and, above all, on the most current risk assessment and analysis. The paper describes all changes and updates, which will impact the Italian current National regulation. A total of 58 animal diseases have been included in the Annex II (“Listing”) and Annex IV (“Categorization”) of the new Delegated Act (DA 2018/1629). Five diseases comprising the great viral epizooties were automatically included on the list because of their primary importance. These diseases include foot and mouth disease (FMD), African swine fever (ASF), classical swine fever (CSF), highly pathogenic avian influenza (HPAI), and African horse sickness (AHS). Another 53 diseases have been identified by the ad hoc assessment on listing and categorization of animal diseases developed by the European Food Safety Association. Seventeen communicable diseases of the Order Artiodactlya (sheep, goats, deer, etc.) have been listed including foot and mouth disease, sheep and goat pox, and pestes de petits ruminants. In addition, other endemic diseases affecting more than one species include blue tongue, tuberculosis, brucellosis, and anthrax. There are five categories (A-E) based on the degree of action to be undertaken throughout the EU for each disease. These vary from complete eradication for diseases not normally found in the EU like FMD (category A) for establishing surveillance for diseases like West Nile that present high risk but lack control tools (category E).

scholarly journals Serosurveillance of foot and mouth disease in Karnataka state, India: a 3 years study

VirusDisease ◽  
2016 ◽  
Vol 27 (3) ◽  
pp. 294-302 ◽  
Author(s):  
Raveendra Hegde ◽  
Srikanth Kowalli ◽  
K. Nagaraja ◽  
N. K. Dharanesha ◽  
C. M. Seema ◽  
...  
Keyword(s):  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Karnataka State ◽  
Foot And Mouth
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