Distal Intravenous Regional Anaesthesia for Claw Diseases in Bovines

The bovine having surgical ailments of claw, were divided in to two groups having six animals/limbs in each group. Tourniquet for standard and modified intravenous regional anesthesia (IVRA), was placed circumferentially at the middle of the metacarpus and just below dewclaw in group I and II, respectively. Lignocaine was injected @ 4 mg/kg and 2 mg/kg b.wt. in group I and group II animals, respectively. In group I, pulse rate increased significantly P andlt; 0.05 at 20 and 30 minutes. Heart rate increased significantly P andlt; 0.05 at 20 minute and 30 minute interval in group I and II animals, respectively. In animal of both groups, oxygen saturation significantly P andlt; 0.05 decreased during study time period. Systolic pressure significantly increased at 15, 20 and 20 minutes in group I animals. It was concluded that modified IVRA technique was safer as compared to standard IVRA..

Download Full-text

INTRAVENOUS REGIONAL ANESTHESIA (BIERS BLOCK);

The Professional Medical Journal ◽

10.29309/tpmj/2012.19.05.2333 ◽

2012 ◽

Vol 19 (05) ◽

pp. 710-714

Author(s):

Muhammad ASGHER ◽

ASIM GHAURI ◽

MUHAMMAD ABDULLAH ◽

Tariq Abassi

Keyword(s):

Regional Anaesthesia ◽

Military Hospital ◽

P Value ◽

Complete Evaluation ◽

Intravenous Regional Anesthesia ◽

Number Of Patients ◽

Group A ◽

The Mean ◽

Group B ◽

Intravenous Regional Anaesthesia

Objective: To compare the analgesic effects of combination of 0.5% Lidocaine plus Ketorolac in intravenous regionalanaesthesia technique with those of Lidocaine (0.5%) alone to prevent post operative pain after intravenous regional anaesthesia (Biersblock). Study design: Randomized Control Trial. Place and duration of study: The study was carried out at Department of Anaesthesiology,Intensive Care and pain management, Combined Military hospital, Rawalpindi from July 2008 to February 2009. Patients and Methods: Thestudy was conducted after complete evaluation of risk / benefit ratio to the patients. On the basis of random number method the patients weredivided into two equal groups (group A and group B). The number of patients in each group was 75. Group A was assigned Lidocaine in a dose of200mg 40ml of 0.5% solution and group B was assigned injection Ketorolac 30mg added to Lidocaine in a dose of 200mg 40ml of 0.5% solution.The patients were kept in post anaesthesia care unit for two hours and pain intensity was measured by visual analogue scale(VAS) on 15,30minutes,1hour, 1.5 and at 2 hours after the cuff deflation. The analgesic efficacy recorded on the basis of visual analog scale of two groups, wascompared using student’s t - test. p value of less than 0.05 was considered statistically significant. Results: In group A 33 males and 42 femaleswere enrolled for the study while in group B there were 38 males and 37 females. The mean age of the patients in group A was 34.31 ± 6.03years while in group B was 32.99 ± 6.08 years. Patients were also classified according to ASA classification in which 87 patients were classifiedas ASA – I and 63 patients as ASA – II. Group B which received Ketorolac in addition to Lidocaine for Bier’s block had low visual analogue scoresas compared to group A which received only Lidocaine for Bier’s block. P values obtained after the comparison of the mean VAS of two groupsat 15 minutes, 30 minutes, 1 hour, 1.5 hours and 2 hours were all less than 0.05 (0.002 for 15 minutes, 0.004 for 30 minutes, 0.001 for 1 hour,0.004 for 1.5 hours and 0.001 for 2 hours). Conclusions: Ketorolac improves the postoperative analgesia markedly when used with Lidocainein intravenous regional anaesthesia.

Download Full-text

Peculiarities of the state of peripheral oxygenation of tissues in different kinds of combined anesthesia in children with congenital surgical pathology

ScienceRise Medical Science ◽

10.15587/2519-4798.2021.224662 ◽

2021 ◽

pp. 49-52

Author(s):

Aleksey Vlasov

Keyword(s):

Heart Rate ◽

Pulse Oximetry ◽

Regional Anesthesia ◽

Congenital Malformations ◽

Oxygen Deficiency ◽

The State ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Combined Anesthesia

In the presented work, we have assessed the features of peripheral oxygenation in children with congenital malformations of the surgical profile under various types of combined anesthesia. The aim of the study. To assess the state of peripheral oxygenation in newborns and infants with congenital malformations with various types of anesthetic support. Materials and research methods. A retrospective study included 150 newborns and infants with congenital malformations of the surgical profile, depending on the anesthesia (inhalation + regional anesthesia; inhalation + intravenous anesthesia and total intravenous). The parameters of pulse oximetry were analyzed: peripheral oxygenation, heart rate. Additionally, the concentration of oxygen in the respiratory mixture of children was taken into account. Research results. Peripheral saturation did not critically decrease at all stages of observation, with the exception of a decrease in the indicator in children of group I compared with group III at the stage of induction into anesthesia (97.79±2.45 versus 98.79±1.63, at p˂0.05, respectively) and at the most painful moment of the operation (96.29±3.47 versus 98.10±2.47, with p˂0.05). At the painful moment of the operation, it was in children of group I that a drop in heart rate was noted compared to group III (127.98±13.77 and 136.10±15.37, respectively, with p˂0.05) and group II (134.02±18.43, at p>0.05) against the background of a decrease in SpO2. Newborns and group I infants required higher oxygen concentrations in the breathing mixture. A significant difference in the indicator is noted between groups I and III at the traumatic stage – 0.47±0.29 and 0.33±0.2, with p˂0.05, respectively, and immediately after the operation – 0.34±0,19 and 0.26±0.13, with p˂0.05, respectively. Conclusions. The expediency and effectiveness of pulse oximetry for children with congenital malformations at all stages of anesthetic support during surgical treatment was confirmed. The risk group for the formation of oxygen deficiency in organs and tissues, the occurrence of pain during the operation were newborns and infants, for whom combined anesthesia was chosen in the form of an inhalation method and regional anesthesia. In the case of the appointment of this type of anesthetic support, it is necessary to more closely monitor the indicators and promptly correct the deterioration of the child's condition

Download Full-text

Breast Feeding as Analgesia in Neonates: A Randomized Controlled Trial

Journal of Nepal Paediatric Society ◽

10.3126/jnps.v36i3.15688 ◽

2017 ◽

Vol 36 (3) ◽

pp. 238-242 ◽

Cited By ~ 1

Author(s):

Rajesh Kumar Singh ◽

Ashish Kumar Simalti ◽

Daljit Singh

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Randomized Controlled Trial ◽

Oxygen Saturation ◽

Breast Feeding ◽

Controlled Trial ◽

Randomized Controlled ◽

Group I ◽

Heel Prick ◽

Breast Fed

Introduction: Major myth regarding neonatal pain suggests that neonates because of their neurological immaturity do not experience pain. Although exact mechanism is not known, it is proposed that breast feeding through combination of various senses and the closeness of the infant’s mother, saturates the senses thus reducing perception of noxious stimuli. The objective of this study was to investigate the analgesic effect of breastfeeding during blood sampling through heel lance in healthy term neonates.Material and Methods: This was a Randomized controlled trial done in a Tertiary level Neonatal Intensive Care Unit. Sixty healthy term newborns, undergoing heel prick were included in study. Neonates were randomly assigned to two groups: Group I (breastfed) with; Group II (not breast fed). Babies were given heel prick and crying time, Heart rate, SpO2 and BP monitored. Changes in various physiological parameters following a heel prick were studied in two groups.Results: Neonates in both groups expressed pain by crying, increase in heart rate, fall in transcutaneous oxygen saturation and rise in blood pressure. Compared to control group, the babies who were breast fed were found to have lesser crying time (40.04 sec and 69.09 sec respectively, p<0.05) and lesser rise in heart rate (rise of 21.78 and 34.46 bpm respectively, p<0.03). In the breast fed group there was a trend to a lesser decrease in oxygen saturation and lesser rise in blood pressure though this was not statistically significant.Conclusion: Breast feeding offers a quick and effective means of reducing pain in neonates during routine neonatal procedures.J Nepal Paediatr Soc 2016;36(3):238-242

Download Full-text

Pediatric laparoscopy and adaptive oxygenation and hemodynamic changes

Pediatric Reports ◽

10.4081/pr.2017.7214 ◽

2017 ◽

Vol 9 (2) ◽

Cited By ~ 9

Author(s):

Gloria Pelizzo ◽

Veronica Carlini ◽

Giulio Iacob ◽

Noemi Pasqua ◽

Giuseppe Maggio ◽

...

Keyword(s):

Heart Rate ◽

Oxygen Saturation ◽

Open Surgery ◽

Systolic Pressure ◽

Open Group ◽

Anesthesia Induction ◽

Hemodynamic Changes ◽

Peripheral Oxygen Saturation ◽

Adaptive Changes ◽

Pediatric Laparoscopy

Adaptive changes in oxygenation and hemodynamics are evaluated during pediatric laparoscopy. The children underwent laparoscopy (LAP Group, n=20) or open surgery (Open Group, n=10). Regional cerebral (rScO2) and peripheral oxygen saturation (SpO2), heart rate (HR), diastolic (DP) and systolic pressure (SP) were monitored at different intervals: basal (T0); anesthesia induction (T1); CO2PP insufflation (T2); surgery (T3); CO2PP cessation (T4); before extubation (T5). At T1, in both the LAP and Open groups significant changes in rScO2, DP and SP were recorded compared with T0; a decrease in SatO2 was also observed at T5. In the LAP group, at T2, changes in HR related to CO2PP pressure and in DP and SP related to IAP were noted; at T4, a SP change associated with CO2PP desufflation was recorded. Open group, at T3 and T5 showed lower rScO2 values compared with T1. Pneuperitoneum and anesthesia are influent to induce hemodynamics changes during laparoscopy.

Download Full-text

Addition of Dexmedetomidine to Low Dose Solution of Lidocaine for Intravenous Regional Anesthesia A Randomized Study

JMS SKIMS ◽

10.33883/jms.v19i1.277 ◽

2016 ◽

Vol 19 (1) ◽

pp. 21-25

Author(s):

Ghulam Mohammed Mir ◽

Firdose Shafi Shiekh ◽

Arif Nazir

Keyword(s):

Local Anesthesia ◽

Regional Anesthesia ◽

Postoperative Analgesia ◽

Low Dose ◽

Tourniquet Pain ◽

Intravenous Regional Anesthesia ◽

Group I ◽

Significant Difference ◽

Recovery Times

Background and Aims: Intravenous Regional Anesthesia (IVRA) provides analgesia of distal part of limb by intravenous injection of local anesthesia in to the vein of the same limb, while the circulation to the limb is occluded by application of tourniquet. However, IVRAis limited by local anesthesia toxicity, tourniquet pain and absence of postoperative analgesia. Various additives to local anesthetics such as ketamine, clonidine, opiods, NSAIDs are used to address these issues. The aim of our study was to evaluate the effectiveness of Dexmedetomidine to low dose Lidocaine solution for IVRA.Patients and Methods: A prospective, randomized double blind study was conducted on 60 patients divided in to two groups of thirty each; Group I patients received 40 ml of Lidocaine 0.25% while Group II patients received 40 ml of 0.25% of lidocaine mixed with I mcg/kg of dexmedetomidine. The motor and sensory block onset and recovery times were assessed. Tourniquet pain and sedation score were assessed intraoperatively and postoperatively.Results: Sensory and motor block onset times were shorter and recovery times were prolonged in Dexmedetomidine group. The quality of anesthesia was better in the Dexmedetomidine group and the fentanyl dose required was also lower in the dexmedetomidine group. There was a significant difference in the postoperative analgesia time which was demonstrated by less use of intramuscular diclofenac in dexmedetomidine group.Conclusions: A safe intravenous dose of lidocaine can be used for IVRA for superficial hand surgery, and the addition of I mcg /kg dexmedetomidine shortened the onset times for both sensory and motor blockade and improved the quality of anesthesia, with prolonged postoperative analgesia time. By adding dexmedetomidine we were able to reduce the dose of lidocaine to 0.25% concentration without compromising analgesia. JMS 2016; 19(1):21-25

Download Full-text

Two Levels of Negative Pressure in Open Endotracheal Tube Suctioning on Physiological Indices

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl4.3741 ◽

2020 ◽

Vol 11 (SPL4) ◽

pp. 70-80

Author(s):

Sheeba Rajakumari S ◽

Thenmozhi P ◽

Kala Barathi S

Keyword(s):

Heart Rate ◽

Oxygen Saturation ◽

Respiratory Rate ◽

Endotracheal Tube ◽

Negative Pressure ◽

Physiological Indices ◽

Group I ◽

Group Ii ◽

High Level ◽

Experimental Group

Endotracheal tube suctioning is a vital component of bronchial hygiene therapy by applying negative pressure to facilitate the removal of pulmonary secretions resulting in promotion of gas exchange. Hence the study was conducted to compare the effect of two different levels of 120mmHg and 200mmHg of negative pressure in open endotracheal tube suctioning on physiological indices. Pre-experimental research design was adopted to conduct the study with 60 samples and were allocated into experimental group I (n=30) and experimental group II (n=30). Pre-test assessment was done by assessing Oxygen saturation, respiratory rate, heart rate and mean arterial pressure for both the groups. Open endotracheal tube suctioning was done by applying negative pressure of 120 mmHg to experimental group I and 200 mmHg to experimental group II. Post-test was done immediately, 5 minutes, and 20 minutes after suctioning for both experimental groups. The results of the study reveal the significant changes in both the group however highly significant changes observed in oxygen saturation (p<0.001), respiratory rate (p<0.001), and heart rate (p<0.001) in high level negative pressure. The findings of the study concluded that 200 mmHg negative pressure is safe and can be recommended for open endotracheal tube suctioning for effective oxygen saturation, respiratory rate, and heart rate.

Download Full-text

The Effects of Passive and Active Smoking on Brachial and radial Blood Pressure and Some Other Physical Factors in Healthy Young Adults

Science Journal of University of Zakho ◽

10.25271/2017.5.3.394 ◽

2017 ◽

Vol 5 (3) ◽

pp. 259

Author(s):

Shireen H. Ramadhan ◽

Shamil K. Talal ◽

Wasfiya A. Moner

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Oxygen Saturation ◽

Oxygen Concentration ◽

Tobacco Smoke ◽

Blood Pressure Measurement ◽

Reference Level ◽

Physical Factors ◽

New Device ◽

Active Smoker

Tobacco smoke is enormously harmful to human health, thereâ€™s no safe way to smoke. The primary objective of this study is to analyze the role of tobacco smoke compounds and their ability to damage the cardiovascular system and, in particular, to interfere with blood pressure (Brachial and radial pressure), heart rate and partly on the percentage blood Oxygen saturation. A new device has been manufactured which is unique for measuring the level of smoke, to obtained privies readings, the device had fixed to the first reference level آ and starting up from it. The effect of smoking has been studied on (26) male passive (26) active smoker volunteer, (14) female passive and (14) female active smoker participants. The results has been showed that the blood pressure and heart rate has been increased with increasing the number of cigarettes in both genders for passive and active smokers. However, this effect for male was more pronounced comparing with females for passive and active smokers. In the case of oxygen saturation concentration percentage, for males the change of oxygen concentration percentage was not stable. In other words, it was fluctuated with the number of cigarettes. But for females the oxygen concentration was decreased but not too much. This means that this effect was not pronounced. this study found آ that the most pronounced effect has been shown by maleâ€™s comparison to females for both passive and active smokers. As well as in nonsmokerâ€™s males, the relation between heart rate and smoke level is inversely proportional. While in male and female smokers and female nonsmokers the relation is proportional. In all cases the relation between the smoke level and time of smoking is inversely proportional. Finally males& females are affected differently by tobacco use; the sensitivities to smoke for males are higher than in females for passive and active smokers in both brachial and radial blood pressure measurement.

Download Full-text