scholarly journals IMMUNOLOGICAL INDICES OF THE HUMAN IN CONDITIONS OF THE APPLICATION OF INDIVIDUAL MEANS OF PROTECTION OF RESPIRATORY ORGANS

2019 ◽  
Vol 96 (8) ◽  
pp. 717-720
Author(s):  
Yury Yu. Byalovskiy ◽  
S. V. Bulatetskiy ◽  
V. A. Kiryushin ◽  
N. I. Prokhorov
Keyword(s):  
Respiratory Protection ◽  
Respiratory Resistance ◽  
Population Composition ◽  
Short Term ◽  
Immunological Status ◽  
Inspiratory Resistance ◽  
Additional Resistance ◽  
Protection Devices ◽  
Resistive Loads ◽  
Resistance To Respiration

The purpose of the work was to study reactions of the immune system with the use of additional respiratory resistance arising from the use of personal respiratory protection. The inspiratory resistance to respiration of 20, 40 and 60% Pmmax was used. The study involved 26 male and female cases at the average age of 21,22,23 years. Based on the results of the study the short-term (3 minutes) effect of inspiratory resistive loads was shown to have a pronounced effect on the population and subpopulation composition of blood lymphocytes, practically without changing the level of secreted immunoglobulins. Different values of additional resistance to respiration were noted to statistically significantly change the level of biogenic amines: the concentration of epinephrine and norepinephrine with elevating values of resistive loads progressively increased; the serotonin concentration shows the opposite dynamics. The work demonstrates the additional respiratory resistance of 20% Pmmax fail to change the immunological status of the subjects. The resistive respiratory load of 40% Pmmax caused immunosuppressive changes in the population composition of lymphocytes and indices of nonspecific immunological resistance. An additional respiratory resistance of 60% Pmmax induced an immunostimulatory effect in the change in the population composition of lymphocytes and in indices of nonspecific immunological resistance. Based on the data obtained, a suggestion has been made that in designing individual respiratory protection devices it is advisable to limit the value of additional inspiratory resistance to respiration of 20% Pmmax.

scholarly journals PULMONARY GAS EXCHANGE AND ACID-BASE STATUS OF BLOOD UNDER THE USE OF MEANS FOR INDIVIDUAL PROTECTION OF RESPIRATORY ORGANS

2018 ◽  
Vol 97 (5) ◽  
pp. 445-448
Author(s):  
Yury Yu. Byalovsky ◽  
S. V. Bulatetsky ◽  
V. A. Kiryushin ◽  
N. I. Prokhorov ◽  
V. N. Abrosimov ◽  
...  
Keyword(s):  
Gas Exchange ◽  
Personal Protective Equipment ◽  
Pulmonary Gas Exchange ◽  
Respiratory Pattern ◽  
Preliminary Training ◽  
Protective Equipment ◽  
Respiratory Resistance ◽  
Acid Base ◽  
Inspiratory Resistance ◽  
Additional Resistance

The aim of the study was to evaluate the effect of the duration of training on the use of personal respiratory protective equipment on indices of pulmonary gas exchange. Simulation of conditions for the use of personal respiratory protective equipment was carried out at the inspiratory resistance of 40, 60, 70 and 80% Pmmax. The study included 38 healthy male subjects aged 20 to 36 years. According to the results of the study, under the use of personal protective equipment for the respiratory system, preliminary training was shown to be essential. In the subjects without preliminary training, the use of personal protective equipment was followed by a weak change in the nature of the respiratory pattern. After the preliminary training subjects had an adaptive rearrangement of the respiratory pattern, consisted of the decline in breathing movements as the respiratory resistance increased. Preliminary training to the exposure of additional resistance to breathing, altered pulmonary gas exchange and acid-base state of blood. The trained subjects had higher pCO2 blood values and lower values of pO2. They showed a greater deficit of buffer bases of plasma compared to untrained ones. This fact testified the preliminary training for the use of personal respiratory protective equipment (long-term adaptation) changed the gas composition and acid-base state of the blood to be a more economical mode of the discharge of buffer systems. On the basis of the data obtained, the preliminary training for increased respiratory resistance was suggested to be advisable before the using personal respiratory protective equipment.

scholarly journals Use of Respiratory Protection Devices by Medical Students During the COVID-19 Pandemic

2021 ◽  
Vol 18 (11) ◽  
pp. 5834
Author(s):  
Ekaterina A. Shashina ◽  
Valentina V. Makarova ◽  
Denis V. Shcherbakov ◽  
Tatiana S. Isiutina-Fedotkova ◽  
Nadezhda N. Zabroda ◽  
...  
Keyword(s):  
Medical Students ◽  
Face Mask ◽  
Protective Measure ◽  
Protective Equipment ◽  
Respiratory Protection ◽  
Prevention Measures ◽  
Protection Devices ◽  
Individual Use

The use of face masks has assumed a leading spot among nonspecific prevention measures during the coronavirus pandemic. The effectiveness of this protective measure depends on the specifics of individual use. The purpose of our study was to analyze the use of respiratory protective equipment (RPE) by medical students during the COVID-19 pandemic. The evaluation of face mask use was based on the results of a survey of medical students at Sechenov University. There were 988 participants in the study: 97.5% used RPE during the pandemic, 89.1% used disposable medical and hygienic face masks, 27.4% used reusable cloth face masks, and 13.2% used respirators. The majority of respondents (75.2%) were found to wear face masks correctly. However, 17.0% of the respondents were found to cover only their mouths with a face mask, while 7.8% reported often shifting their face mask under the chin due to perceived discomfort. Only 25.1% of respondents changed their disposable face mask after 2-3 h of wearing, while 13.0% decontaminated and used it several times. Most cloth face mask users (93.7%) decontaminated their marks, but only 55.7% of respondents did so daily. Face masks were most often worn in medical organizations (91.5%), and 1.4% of respondents did not use respiratory protection anywhere. In conclusion, we consider it necessary to introduce a special module on nonspecific prevention in the discipline of hygiene.

scholarly journals Testing the protective efficiency of personal respiratory protection devices in radiologically contaminated environments

2013 ◽  
Vol 28 (1) ◽  
pp. 102-107
Author(s):  
Dusan Rajic ◽  
Negovan Ivankovic ◽  
Natasa Ivankovic ◽  
Marina Ilic ◽  
Zeljko Senic ◽  
...  
Keyword(s):  
High Efficiency ◽  
Face Mask ◽  
Depleted Uranium ◽  
Test Substance ◽  
Respiratory Protection ◽  
Protective Efficiency ◽  
Submicron Scale ◽  
Protection Devices ◽  
Protective Mask

The use of ammunition primed with depleted uranium is one of the hallmarks of modern combat operations, resulting in environmental contamination by particles of depleted uranium and uranium oxide, scattered around in the form of submicron-scale aerosols. This paper examined the protective effectiveness of the Serbian military's M3 protective face mask in relation to the presence of airborne depleted uranium and its by-products. Sodium chloride in solid aerosol form was used as a test substance and adequate physical simulator of such radioactive aerosols because its granulometric (particle) size distribution met the requirements of suitability as a simulator. Determination of aerosol concentration was carried out by flame photometry method, whilst granulometric distribution was determined by an electric particles analyzer. It was established that the total internal leakage of the M3 protective mask was as much a function of the penetration of particles through the combined M3 filter as of the leaks along the fitting line of the user's face mask and the inhalation valve. In terms of its protective effect against aerosols of depleted uranium and associated oxides, the Serbian M3 protective mask was determined to be of high efficiency and physiological suitability.

scholarly journals Injuries related to respiratory masks in the US are very rare

2021 ◽  
Author(s):  
Philip N. Cohen
Keyword(s):  
Census Data ◽  
Incidence Rates ◽  
Common Type ◽  
Respiratory Protection ◽  
Risk Of Falling ◽  
Injury Surveillance System ◽  
Household Products ◽  
The Us ◽  
Protection Devices ◽  
Almost All

Background. Protective facemasks are important for preventing the spread of COVID-19, and almost all Americans have worn them at least some of the time during the pandemic. There are reasonable concerns about some ill effects of mask-wearing, especially for people who wear masks for extended periods, and for the risk of falling as a result of visual obstruction. But there are also unsupported fears and objections stemming from misinformation and fueled by political disputes. Methods. The study analyzed the Consumer Product Safety Commission’s National Electronic Injury Surveillance System (NEISS) for 2020, using the product code for Respiratory Protection Devices, and calculated population incidence rates using Census data. Results. The NEISS included 128 cases, representing an estimated 5122 reported injuries in the population (95% CI 3322, 6922). The overall rate of injury reports was 1.54 per 100,000 U.S. residents (95% CI 1.00, 2.08). People over age 75 had higher rates than the population overall, with 5.27 injuries per 100,000 (95% CI 2.17, 8.37). The most common type of incidents involved facial injuries, rashes, falls, and those that might be considered anxiety-related. Conclusion. Wearing protective face masks is extremely safe, especially in comparison with other common household products, and in light of their protective benefits with regard to prevent the spread of COVID-19. This information may be useful for public health messaging, and for practitioners trying to increase compliance with mask-wearing guidance.

CONDITIONED REFLEX MECHANISMS OF ADAPTATION TO ADDITIONAL BREATHING RESISTANCE

2021 ◽  
pp. 97-105
Author(s):  
Yu.Yu. Byalovskiy ◽  
I.S. Rakitina
Keyword(s):  
Conditioned Reflex ◽  
External Respiration ◽  
Respiratory Resistance ◽  
Conditioned Signal ◽  
Unconditioned Reflex ◽  
Breathing Resistance ◽  
Before And After ◽  
Resistive Loads ◽  
Aversive Behavior ◽  
Respiratory Reflex

The problem of adaptation to additional breathing resistance has recently become more urgent due to the growth of bronchopulmonary diseases. Therefore, there is a natural interest in non-drug strategies compensating resistive breathing in humans. The aim of the study was to assess conditioned reflex changes in the functional state of the subjects under additional breathing resistance. Materials and Methods. The work was carried out on 55 practically healthy subjects of both sexes, aged 18–36. Additional breathing resistance was modeled by inspiratory resistive loads of 40, 60, 70, and 80 % of the maximum intraoral pressure. The conditioned respiratory reflex to resistive respiratory load was developed as a short-delayed conditioned signal with a 30-second period of isolated action. The authors examined behavioral, vegetative, gas and energy indicators of the organism before and after the formation of a conditioned reflex. Results. It was observed that conditioned reflex shifts of physiological parameters in the process of adaptation to additional breathing resistance differ significantly from the corresponding unconditioned reflex changes both in nature and in intensity. Conditioned reflex mechanisms reduce the intensity of shifts in the motor component of the external respiration system, which, apparently, is the main reason to decrease the aversive behavior. Conclusion. Behavioral changes after the formation of a conditioned respiratory reflex to additional respiratory resistance are characterized by a decrease in aversive behavior patterns. The conditioned reflex realization of increasing resistive loads is expressed in a lower physiological cost of adaptation to additional respiratory resistance relative to the unconditioned reflex type of realization. Keywords: adaptation, conditioned respiratory reflex, additional breathing resistance. Проблема приспособления к дополнительному респираторному сопротивлению в последнее время становится все более актуальной в связи с ростом бронхолегочных заболеваний. Поэтому естественен интерес к нелекарственным механизмам компенсации резистивного дыхания человека. Целью исследования являлась оценка условно-рефлекторных изменений функционального состояния испытуемых в условиях дополнительного респираторного сопротивления. Материалы и методы. Работа проведена на 55 практически здоровых испытуемых обоего пола в возрасте от 18 до 36 лет. Дополнительное респираторное сопротивление моделировалось инспираторными резистивными нагрузками величиной 40, 60, 70 и 80 % от максимального внутриротового давления. Условный дыхательный рефлекс на резистивные дыхательные нагрузки вырабатывался по типу короткоотставленного с периодом изолированного действия условного сигнала 30 с. Исследовались поведенческие, вегетативные, газовые и энергетические показатели организма до и после формирования условного рефлекса. Результаты. Показано, что условно-рефлекторные сдвиги физиологических показателей в процессе приспособления к дополнительному респираторному сопротивлению существенно отличаются от соответствующих безусловно-рефлекторных изменений как по характеру, так и по интенсивности. Условно-рефлекторные механизмы уменьшают интенсивность сдвигов моторного компонента системы внешнего дыхания, что, по-видимому, является основной причиной снижения вероятности появления аверсивного поведения. Выводы. Поведенческие изменения после формирования условного дыхательного рефлекса на дополнительное респираторное сопротивление характеризуются снижением вероятности появления аверсивных форм поведения. Условно-рефлекторная реализация возрастающих по интенсивности резистивных нагрузок выражается в меньшей физиологической стоимости приспособления к дополнительному респираторному сопротивлению относительно безусловно-рефлекторного типа реализации. Ключевые слова: приспособление, условный дыхательный рефлекс, дополнительное респираторное сопротивление.

PROBLEM OF PHYSIOLOGICAL ESTIMATION OF NEGATIVE IMPACT OF FILTERING RESPIRATORY PROTECTION DEVICES TO WORKERS

2021 ◽  
Author(s):  
V.I. Lemeshko ◽  
◽  
I.V. Ivanov ◽  
A.M. Geregey ◽  
Keyword(s):  
Human Body ◽  
Negative Impact ◽  
Protective Equipment ◽  
Respiratory Protection ◽  
Physiological Processes ◽  
Foreign Countries ◽  
Modern Methods ◽  
Physiological Assessment ◽  
Protection Devices ◽  
The Impact

Abstract: Filtering respiratory protection devices are widely used in industry and now in healthcare. The tests that these products undergo assess only the technical characteristics, without considering how the personal protective equipment affects the physiological processes of the user. The purpose of this study was to study modern methods of physiological assessment of the negative impact of the use of filtering respiratory protection devices on the human body. Analyzed domestic and foreign publications. The absence of a unified set of physiological methods for assessing the impact of filtering means of personal respiratory protection on the employee's body was established. This may be due to insufficient actualization of this problem both in Russia and in foreign countries.

Social Marketing Campaign Promoting the Use of Respiratory Protection Devices Among Farmers

2014 ◽  
Vol 19 (3) ◽  
pp. 316-324 ◽  
Author(s):  
Lea Pounds ◽  
Ellen Duysen ◽  
Debra Romberger ◽  
Mary E. Cramer ◽  
Mary Wendl ◽  
...  
Keyword(s):  
Social Marketing ◽  
Respiratory Protection ◽  
Marketing Campaign ◽  
Social Marketing Campaign ◽  
Protection Devices

Effects of ozone on cyclooxygenase metabolites in the baboon tracheobronchial tree

1990 ◽  
Vol 69 (1) ◽  
pp. 245-250 ◽  
Author(s):  
J. M. Fouke ◽  
R. A. DeLemos ◽  
M. J. Dunn ◽  
E. R. McFadden
Keyword(s):  
Arachidonic Acid ◽  
Hydrolysis Product ◽  
Tracheobronchial Tree ◽  
Ozone Exposure ◽  
Base Line ◽  
Respiratory Resistance ◽  
Pulmonary Resistance ◽  
Short Term ◽  
Short Term Exposure ◽  
Before And After

Short-term exposure to 0.5 parts per million (ppm) ozone has been shown to cause an increase in respiratory resistance in primates that can be diminished by 50% with pretreatment with cromolyn sodium. Because of the known membrane-stabilizing effects of cromolyn and the resultant inhibition of mediator production, we hypothesized a role for the products of arachidonic acid (AA) metabolism in these events. We exposed five adult male baboons to 0.5 ppm ozone on two occasions, once with cromolyn pretreatment and once without. Pulmonary resistance (RL) was monitored and bronchoalveolar lavage (BAL) was performed before and after each exposure. The BAL was analyzed for a stable hydrolysis product of prostacyclin, 6-keto-prostaglandin (PG) F1 alpha, PGE2, a stable hydrolysis product of thromboxane (Tx) A2, TxB2, and PGF2 alpha. RL increased after ozone exposure (1.62 +/- 0.23 to 3.77 +/- 0.51 cmH2O.l-1.s, difference 2.15; P less than 0.02), and this effect was partially blocked by cromolyn (1.93 +/- 0.09 to 3.18 +/- 0.40 cmH2O.l-1.s, difference 1.25; P less than 0.02). The base-line levels of the metabolites of AA in the BAL were as follows (in pg/ml): 6-keto-PGF1 alpha 72.78 +/- 12.6, PGE2 145.92 +/- 30.52, TxB2 52.52 +/- 9.56, and PGF2 alpha 22.28 +/- 5.42. Ozone exposure had no effect on the level of any of these prostanoids (P = NS). These studies quantify the magnitude of cyclooxygenase products of AA metabolism in BAL from baboon lungs and demonstrate that changes in the levels of these mediators in BAL are not prerequisites for ozone-induced increases in respiratory resistance.(ABSTRACT TRUNCATED AT 250 WORDS)

Usefulness of Pulsed-Field Gel Electrophoresis in Assessing Nosocomial Transmission of Pertussis

1999 ◽  
Vol 20 (11) ◽  
pp. 758-760 ◽  
Author(s):  
Michèle Nouvellon ◽  
Jean-François Gehanno ◽  
Martine Pestel-Caron ◽  
Christian Weber ◽  
Jean-François Lemeland ◽  
...  
Keyword(s):  
Bordetella Pertussis ◽  
Gel Electrophoresis ◽  
Healthcare Workers ◽  
Whooping Cough ◽  
Close Contact ◽  
Pulsed Field Gel Electrophoresis ◽  
Nosocomial Transmission ◽  
Respiratory Protection ◽  
Pulsed Field ◽  
Protection Devices

AbstractDuring a 2-week period, three infants with a cough lasting at least 8 days with whoops, were admitted to the pediatric unit; Bordetella pertussis was isolated from nasopharyngeal aspirates collected from the three infants. Approximately 1 week later, a nurse working on the same unit developed influenza-like symptoms followed by whooping cough; B pertussis was isolated. Isolates from the nurse and from one of the infants were shown to be indistinguishable by pulsed-field gel electrophoresis. These data demonstrate that B pertussis transmission to healthcare workers is possible and emphasize the need to use respiratory protection devices (Droplet Precautions) for healthcare workers having close contact with infected children.

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