scholarly journals Evaluation of the antimicrobial activity of Gooseberry and Wild Apple fruit juices of the northeast region of India

2017 ◽  
Vol 3 ◽  
pp. 1 ◽  
Author(s):  
Kapil Punjabi ◽  
Vidushi K. Chitalia ◽  
Tehmeena Mukadam ◽  
Jaishankar Sharma ◽  
Jinesh Maniar ◽  
...  

<span>A large number of wild fruits belonging to the North Eastern region of India are considered to be nutritionally abundant and traditionally used for the treatment of various ailments. In the present study, juices of Gooseberry and Wild Apple have been evaluated for their antimicrobial activity in its consumable form as a potential source of natural anti-infective agent. The fruit juices were screened for their antibacterial and antifungal activities qualitatively, using the agar well diffusion method followed by quantitative assessment by determining the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). The study revealed that both the fruit juices exhibited broad spectrum antibacterial activity. Considerable activity against drug resistant pathogens such as Methicillin Resistant Staphylococcus aureus (MRSA), Vancomycin Resistant Enterococci (VRE) and Extended Spectrum β-Lactamases (ESBL) producing Gram Negative bacteria (GNB) was observed. Thus, this study highlights the antibacterial efficacy of Wild Apple and Gooseberry fruit juices and augments the beneficiary properties of highly nutritional fruit juices that are specific to the Indian region.</span>

2016 ◽  
Vol 11 (2) ◽  
pp. 248 ◽  
Author(s):  
Kathirvel Poonkodi ◽  
Subban Ravi

<p class="Abstract">The present study was aimed to evaluate the phytochemical screening and antimicrobial activity of the petroleum ether and methanol extracts from the mature leaves of <em>Richardia scabra</em> from India. Disc diffusion method was used to determine the zone inhibition of the tested samples for antibacterial and agar plug method was used to determine the antifungal activity, while the microtube-dilution technique was used to determine the minimum inhibitory concentration. Both extracts showed significant antibacterial and antifungal activities when tested against 10 bacterial and four fungal strains. The minimum inhibitory concentrations of the methanol extract of<em> R. scabra</em> ranged between 12.5–100 μg/mL for bacterial strains. Alkaloids, steroids, flavonoids, fatty acids, terpenoids and simple sugar were detected as phytoconstituents of extracts. To the best of our knowledge, this is the first report against antimicrobial activity of common weed species <em>R. scabra</em> found in India.</p><p> </p>


Author(s):  
Dhanapal Venkatachalam ◽  
Samuel Thavamani ◽  
Aneesh C. Sebastian ◽  
V. B. Anju ◽  
Christy Mathew ◽  
...  

Objective: The objective of the study was to evaluate in-vitro efficacy of antibacterial, and antifungal activities of chloroform extract of leaf of Sida cordifolia L. against some human pathogenic bacterial and fungal strains. S. cordifolia (Malvaceae) is used as anti-rheumatic, analgesic, antipyretic, anti-asthmatic, nasal decongestant, antiviral, laxative, diuretic, aphrodisiac, hypoglycemic, hepatoprotective and in the treatment of Parkinson disease. Methodology: Chloroform extract of S.cordifolia was used for antimicrobial screening. Antibacterial activity was tested against pathogenic bacterial strains Eschericha coli and Staphylococcus aureus. Also antifungal activity was tested against one human pathogenic fungal strain i.e. Candida albicans. Antibacterial and antifungal activities of S. cordifolia extract was carried out by using disc diffusion method. Results: Chloroform extract of S. cordifolia showed the largest zone of inhibition (10mm) against S. aureus at 50µgm/mL and no zone of inhibition against E.coli at 50µgm/ml. Chloroform extract has shown more potent antibacterial activity against S.aureus. Chloroform extract was found to be more effective against human pathogenic fungus C. albicuns. The zone of inhibition of chloroform extract was 10mm.The phytochemical screening demonstrated the presence of different types of compounds like alkaloids, tannins and phenolic compounds which may contribute for the anti-microbial action of this plant.  Conclusions: The results concludes that chloroform extract of S. cordifolia leaf possess antimicrobial activity.


2020 ◽  
Vol 7 (1) ◽  
pp. 71-85
Author(s):  
Kadri Farida ◽  
Boudjeniba Messaoud ◽  
Wathelet Bernard ◽  
Akkal Salah

AbstractCertain phenolics have been recognized to possessing antibacterial and antifungal activities and high levels of flavonoids and tannins have been reported in several varieties of Sorghum bicolor (L.) Moench. Antimicrobial activity and phenolics contents were investigated in five Algerian sorghum seeds. AS20 sorghum extract showed the highest levels of: total phenolics (3214.46±263.64 mg/100 g), flavonoids (32.03±1.64 mg/100 g) and tannins (615.35±6.10 mg/g) contents; however, comparable flavonoids content was recorded in I27 extract. FZ40 and AS12 flavonoids contents were comparable. Screening for antimicrobial activity, carried out by the disc’s diffusion method revealed an antimicrobial potential of sorghum crude extracts against Gram-positive and Gram-negative bacteria and candida albicans yeast. Minimal inhibition concentration determined by microdilution method varied between 0.2 and 2 mg/ml. the lowest value was recorded with F11 and FZ40 extract against Streptococcus pneumoniae and F11 against Escherichia coli. Bacillus subtilis, Staphylococcus aureus ATTCC6538 and MRSA strains showed sensitivity to all extracts. The results show these sorghums as a potential source of natural anti-streptococcal, anti-staphylococcal and anti-candida substances.


2009 ◽  
Vol 4 (1) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Mehmet Öztürk ◽  
Mehmet Emin Duru ◽  
Fatma Aydoğrmuş-Öztürk ◽  
Mansur Harmandar ◽  
Melda Mahlıçlı ◽  
...  

The essential oil from the aerial parts of Stachys cretica L. subsp. smyrnaea Rech. fil. (Lamiaceae), endemic to Turkey, was investigated by using GC and GC-MS. Thirty-four of 37 components, represented 99.7% of the total oil, were identified. The major components of the essential oil were trans-β-caryophyllene (51.0%), germacrene-D (32.8%), α-humulene (3.1%), δ-cadinene (2.1%) and δ-elemene (2.1%). The antimicrobial activity of the essential oil, trans-β-caryophyllene and five different extracts of the aerial parts of S. cretica L. subsp. smyrnaea were investigated by the standard disc diffusion method. The essential oil and trans-β-caryophyllene exhibited antibacterial and antifungal activities. The activity increased with increasing concentrations of the essential oil and the extracts. The essential oil showed antimicrobial activity, particularly against Pseudomonas aeruginosa and Bacillus subtilis. The extracts exhibited either moderate or no activity.


2018 ◽  
Vol 8 (8) ◽  
pp. 1362 ◽  
Author(s):  
Selvakumari Ulagesan ◽  
Hak Kim

Snails have been used both as a food and as a treatment for a variety of medicinal conditions. In this study, seven different snail proteins were evaluated for their antimicrobial activity. Fresh water and land snails of seven different live species were collected and identified. Crude proteins were extracted from seven different snails. The extracted proteins were estimated using Bradford’s method and snail proteins were displayed using a sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) analysis. The seven different snail proteins were evaluated for their antimicrobial activity against various pathogenic bacterial and fungal cultures by agar well diffusion method and MIC (Minimum Inhibitory Concentration). One of the most active, crude proteins was from land snail Cryptozona bistrialis and its protein was capable of completely inhibiting the development of pathogenic bacterial and fungal cultures. This study shows that the land snail C. bistrialis proteins could be used as an antibiotic in biomedical research.


2006 ◽  
Vol 1 (8) ◽  
pp. 1934578X0600100 ◽  
Author(s):  
Hocine Laouer ◽  
Salah Akkal ◽  
Claire Debarnot ◽  
Bruno Canard ◽  
Uwe J. Meierhenrich ◽  
...  

The chemical composition of the essential oil of Saccocalyx satureioides Coss. et Dur. (Lamiaceae) was analyzed by chiral and achiral GC/MS and 42 components were identified. The main constituents were (+)-α-terpineol (35.9%), thymol (15.6%) and borneol (12.4%). The in vitro antibacterial and antifungal activities of the essential oil were assessed by the disc diffusion method, and were significant on the six microorganisms tested. A moderate inhibitory activity against hepatitis C virus polymerase was also evidenced.


Think India ◽  
2019 ◽  
Vol 22 (3) ◽  
pp. 186-192
Author(s):  
Dr. Oinam Ranjit Singh ◽  
Dr. Nushar Bargayary

The Bodo of the North Eastern region of India have their own kinship system to maintain social relationship since ancient periods. Kinship is the expression of social relationship. Kinship may be defined as connection or relationships between persons based on marriage or blood. In each and every society of the world, social relationship is considered to be the more important than the biological bond. The relationship is not socially recognized, it fall outside the realm of kinship. Since kinship is considered as universal, it plays a vital role in the socialization of individuals and the maintenance of social cohesion of the group. Thus, kinship is considered to be the study of the sum total of these relations. The kinship of the Bodo is bilateral. The kin related through the father is known as Bahagi in Bodo whereas the kin to the mother is called Kurma. The nature of social relationships, the kinship terms, kinship behaviours and prescriptive and proscriptive rules are the important themes of the present study.


2020 ◽  
Vol 15 (3) ◽  
pp. 264-273
Author(s):  
Syeda Sabiha Salam ◽  
Pankaj Chetia ◽  
Devid Kardong

Background: Malaria is endemic in various parts of India particularly in the North- Eastern states with Plasmodium falciparum-the most prevalent human malaria parasite. Plantderived compounds have always received tremendous importance in the area of drug discovery and development and scientific study of traditional medicinal plants are of great importance to mankind. Objective: The present work deals with the computational study of some antimalarial compounds obtained from a few medicinal plants used by the tribal inhabitants of the North-Eastern region of India for treating malaria. Methods: In silico methodologies were performed to study the ligand-receptor interactions. Target was identified based on the pharmacophore mapping approach. A total of 18 plant-derived compounds were investigated in order to estimate the binding energies of the compounds with their drug target through molecular docking using Autodock 4.2. ADMET filtering for determining the pharmacokinetic properties of the compounds was done using Mobyle@RPBS server. Subsequent Quantitative-Structure Activity Relationship analysis for bioactivity prediction (IC50) of the compounds was done using Easy QSAR 1.0. Results: The docking result identified Salannin to be the most potent Plasmepsin II inhibitor while the QSAR analysis identified Lupeol to have the least IC50 value. Most of the compounds have passed the ADME/Tox filtration. Conclusion: Salannin and Lupeol were found to be the most potent antimalarial compounds that can act as successful inhibitors against Plasmepsin II of P. falciparum. The compounds Salannin and Lupeol are found in Azadirachta indica and Swertia chirata plants respectively, abundantly available in the North-Eastern region of India and used by many inhabiting tribes for the treatment of malaria and its symptoms.


2021 ◽  
pp. 001955612110065
Author(s):  
Rita Jain ◽  
Sanjay Kumar

To the North Eastern Region (NER) of India, lie the unexplored states of the Indian Union. This region holds a unique place in the federal structure of India. This article attempts to scrutinise the diversity of NER, along with the potential of the National Cadet Corps (NCC) as a medium to change, uplift and assimilate it with pan India. The article aims to comprehend how NER can accommodate the regional identities and cultural affinities with Indian mainstream identity through the intervention of NCC at college and university level. The methodology of this article is based on secondary resources such as published books, journals, web pages, reports, newspapers and online sources. The article is analytical and descriptive in nature based on thematic approach.


Sign in / Sign up

Export Citation Format

Share Document