scholarly journals The Characteristics of Children with UTI Due to ESBL-producing Bacteria at Dr. Soetomo General Hospital, Surabaya

2021 ◽  
Vol 4 (1) ◽  
pp. 38
Author(s):  
Ida Fitriawati ◽  
Manik Retno Wahyunitisari ◽  
Risky Vitria Prasetyo ◽  
Dwiyanti Puspitasari
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
General Hospital ◽  
Clinical Characteristics ◽  
Total Duration ◽  
High Fever ◽  
Empiric Antibiotic Therapy ◽  
Tract Infections

Introduction: Urinary tract infection (UTI) by extended-spectrum beta-lactamase-producing bacteria often results in a delay in obtaining appropriate antibiotics. The information on patients’ clinical characteristics is necessary for early recognition and the selection of empiric antibiotic therapy. This study aims to investigate the clinical characteristics and the length of therapy of patients with urinary tract infections by those resistant bacteria.Method: This study utilizes a cross-sectional design. Medical records of hospitalized children aged 1-18 months with UTI due to ESBL-producing bacteria at Dr. Soetomo general hospital between January 1, 2017 - July 20, 2020, were reviewed retrospectively. Variables of interest were the demographic data, underlying diseases, causative organism, clinical presentation, maximal body temperature, and length of antibiotic therapy.Results: Among 37 patients enrolled, 25 patients were female. The incidence of urinary tract infection in children was dominated by age 1-12 months old (37.8%). Urological abnormalities were presented in 62.2% of patients. ESBL-producing Escherichia coli was the most common isolated uropathogen (62.2%). High fever was found in 10/28 patients (35.7%). In 17 patients (45.9%), the total duration of antibiotic therapy was 8-14 days.Conclusion: In children with UTI, especially in the infant group, who had urological abnormality or present with a high fever, and who do not respond to empiric therapy should be suspected of developing UTI due to ESBL-producing bacteria.

Cephazolin Sodium—An In Vivo and In Vitro Evaluation of 100 Patients with Urinary Tract Infections

1975 ◽  
Vol 20 (5) ◽  
pp. 259-260
Author(s):  
Diana M. D. Rimmer
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
General Hospital ◽  
Urinary Tract Infections ◽  
Antimicrobial Agents ◽  
Random Group ◽  
Tract Infections

A random group of 100 patients in a general hospital were treated with cephazolin sodium for proven urinary tract infections. Sixty-six per cent had conditions predisposing to urinary tract infection. Under these somewhat difficult conditions the original infecting organism remained absent from the urine of 75 per cent of the 70 patients followed in the 3rd to 6th week period. This compares very favourably with response to other antimicrobial agents currently used in urinary tract infections.

scholarly journals Therapy of urinary tract infections in gynecological practice

2019 ◽  
pp. 87-92
Author(s):  
A. A. Balushkina ◽  
N. E. Kan ◽  
V. L. Tyutyunnik
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
Acute Cystitis ◽  
Fundamental Investigation ◽  
Therapeutic Decisions ◽  
Tract Infections ◽  
Uropathogenic Bacteria

The urinary tract infection continue to exert significant impact on millions of patients worldwide, most of whom are otherwise healthy reproductive women. Antibiotic therapy for acute cystitis does not prevent recurrences, which plague up to one fourth of women after an initial urinary tract infection. Rising antimicrobial resistance among uropathogenic bacteria further complicates therapeutic decisions, necessitating new approaches based on fundamental investigation.

Evaluation of Short-Term Antibiotic Therapy in Children with Uncomplicated Urinary Tract Infections

PEDIATRICS ◽  
1981 ◽  
Vol 67 (6) ◽  
pp. 796-801
Author(s):  
George H. McCracken ◽  
Charles M. Ginsburg ◽  
V. Namasonthi ◽  
Mary Petruska
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
Term Therapy ◽  
Recurrent Infections ◽  
Short Term ◽  
Lower Urinary Tract Infection ◽  
Reactive Protein ◽  
Tract Infections

This study was designed to determine whether serum C-reactive protein (CRP) concentrations could be used to identify children with uncomplicated lower urinary tract infection who would respond favorably to short-term antibiotic therapy. A one-day or ten-day regimen of cefadroxil (30 mg/kg/day in two divided doses) was assigned randomly to 80 children who had acute urinary tract infection and CRP concentrations <28 µg/ml (CRP-negative group). Ten days of cefadroxil therapy was used to treat 44 children with urinary tract infection and CRP values ≥28 µg/ml (CRP-positive group). The clinical and laboratory characteristics of the children in the two CRP-negative therapy groups were similar to, but different from those of children with CRP-positive infections. Recurrent infections occurred significantly more often at four to five days after completion of therapy in CRP-negative children who received one day (44.4%) compared to ten days (20%) of cefadroxil therapy (P < .05). When data from this study were combined with those from our previously published investigation of short-term antibiotic therapy in CRP-negative children, a significantly larger percentage of recurrences was documented immediately after one or four days of antibiotics (79%) compared to recurrences after the standard ten-day regimen (4l%). Additionally, the total rate of recurrent infections for all children in both studies was significantly larger in those who received short-term therapy (48%) as opposed to conventional therapy (34%). These data indicate that short-term antibiotic therapy is less effective than the conventional ten-day regimen in children with CRP-negative urinary tract infection.

scholarly journals Improvement of effectiveness in treatment for urinary tract infection in pregnant women

2021 ◽  
pp. 7-11
Author(s):  
Iu.V. Davydova ◽  
◽  
A.Y. Lymanskaya ◽  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Asymptomatic Bacteriuria ◽  
Well Being ◽  
Complex Treatment ◽  
Tract Infections

The aim is to evaluate the effectiveness of Phytolysin Active prescription in therapy of urinary tract infections in pregnant women. Materials and methods. The efficacy of Phytolysin Active (1 capsule per day for 21 days) in the complex treatment for urinary tract infection was studied in comparison with the group of pregnant women using traditional antimicrobial therapy. The first group consisted of 27 pregnant women who received complex treatment (antibiotic therapy + Phytolysin Active), the second consisted of 25 women who used exclusively antibiotic therapy. Among pregnant women in the first group, symptomatic gestational cystitis was observed in 9 (33.3%) cases, and in the second group in 8 (32%) patients. Results. The effectiveness of combination therapy with the use of Phytolysin Active was proved by significant improvement in general well-being and disappearance of cystitis symptoms in 8 (88.9%) women compared with 5 (62.5%) patients in the treatment group who used exclusively antimicrobial drugs. After treatment with the addition of Phytolysin Active to antibiotic therapy, Escherichiaсoli pathogen, which is most often diagnosed in this pathology, was observed in 1 (3.7%) women compared to 5 (20%) cases in the second group. Also, 25 (92.6%) women of the first group had no recurrence of urinary tract infections for 3 months. Conclusions. Complex treatment of asymptomatic bacteriuria in pregnant women with the use of the drug Phytolysin Active is more effective than the use of antibiotic therapy alone, which is proved by the high rate of the pathogen elimination and absence of infection recurrence for 3 months. The synergistic action of two active components of Phytolysin Active (Polpharma) – cranberry proanthocyanidins and lactobacillus acidophilus – improves the effectiveness of treatment and prevents relapse. The study was carried out in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethics Committee of the institution. The informed consent of women was obtained for the research. The authors declare no conflicts of interest. Key words: pregnancy, urinary tract infections, treatments, herbal medicine, cranberry, lactobacilli.

scholarly journals Urinary tract infections in obstetrics and gynecology: current issues of diagnosis and antibiotic therapy

2020 ◽  
Vol 68 (6) ◽  
pp. 19-28
Author(s):  
Tatyana A. Khusnutdinova
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
Urinary Tract Infections ◽  
Clinical Manifestations ◽  
Clinical Importance ◽  
Obstetrics And Gynecology ◽  
Tract Infections

Urinary tract infections are among the most common infectious diseases in women and often complicate the course of pregnancy. This article reviews current scientific and methodical literature on the management of pregnant women with urinary tract infection. Aspects of clinical importance of urinary tract infections during pregnancy (epidemiology, clinical manifestations, and complications) are discussed, with current recommendations for diagnosis and management of urinary tract infections summarized. Special attention is paid to the problem of antibiotic resistance of urinary tract infection pathogens.

Risk Factors in Diabetes and Pregnant Women with Urinary Tract Infections Compared to Younger Aged Female.

2018 ◽  
Vol 1 (3) ◽  
pp. 26-38
Author(s):  
Abdulghani Mohamed Alsamarai ◽  
Shler Ali Khorshed
Keyword(s):  
Risk Factors ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Female Student ◽  
Mean Value ◽  
Infected Female ◽  
Significant Difference ◽  
Tract Infections

Background: Urinary tract infection is common with health impact in women and characterised by failure to treatment and recurrent episodes. Aim: This study was conducted to determine the risk factors for the development of urinary tract infection in diabetic and pregnant women in comparison to student female. Materials and methods: A prospective cross-sectional study conducted during the period from 1st of June 2015 to the end of January 2016. The population included in the study are 563 women, of them 425 were outpatients, and 138 were inpatients. Their age range between 18 and 80 years, with a mean age of 33.59±15.29 years. Urine samples collected and cultured on blood agar and MacConkey agar by spread plate technique. Bacterial colonies with different morphology were selected, purified and identified according to their biochemical characteristics using conventional standard methods. Results: In diabetic women, there were no significant difference in mean age and BMI values between culture positive and culture negative groups. However, pus cell mean scale was significantly higher [P=0.000] in women with urinary tract infection [1.76±1.25] than in those with negative culture [0.69±1.00]. In pregnant women, BMI mean value was significantly [P=0.013] lower in pregnant women with UTI [26.14] as compared to those without infection [26.99]. Pus cell scale mean value was significantly [P=0.000] higher in pregnant women with UTI [1.55] than women with negative UTI [0.85]. While there was no significant difference in mean age between UTI positive and negative pregnant women. In female student, there was a significant difference between UTI infected and non-infected in mean age [P=0.041] and pus cell scale [P=0.000]. However, BMI was not significantly different between infected and non-infected female student. Other risk factors association are variables in the 3 groups when analysed using X2, while AUC and OR show different trends of association between risk factors and UTI. Conclusion: BMI, pus cell scale, child number, delivery method, operation history and hospital setting were significantly associated with culture positivity in the 3 studied groups as determined by AUC. While OR confirmed association with pus sale scale in the 3 groups.

Detection of tox A gene in Pseudomonas aeruginosa that isolates from different clinical cases by using PCR.

2018 ◽  
pp. 26
Author(s):  
Rana M. Abdullah Al-Shwaikh ◽  
Abbas Falih Alornaaouti
Keyword(s):  
Molecular Weight ◽  
Pseudomonas Aeruginosa ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Otitis Media ◽  
Urinary Tract Infections ◽  
Gel Electrophoresis ◽  
Wound Infections ◽  
Tract Infections

       Current study obtained (75) isolate of Pseudomonas aeruginosa collected from different cases included : 28 isolates from otitis media, 23 isolates from burn infections, 10 isolates from wound infections, 8 isolates from urinary tract infections and 6 isolates from blood, during the period between 1/9/2014 to 1/11/2014        The result revealed that the tox A gene was present in 54 isolates (72%) of Pseudomonas aeruginosa. The gel electrophoresis showed that the molecular weight of tox A gene was 352 bp. The result shows 17 isolates (60.71%) from otitis media has tox A gene, 18 isolates (78.26%) from burn followed by 8 isolate (80%) from wound infection and 5 isolates (62.5%) from urinary tract infection , finally 6 isolates (100%) from blood have this gene.

URINARY INFECTION AT DEPARTMENT OF UROLOGY OF HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

2018 ◽  
pp. 100-108
Author(s):  
Dinh Khanh Le ◽  
Dinh Dam Le ◽  
Khoa Hung Nguyen ◽  
Xuan My Nguyen ◽  
Minh Nhat Vo ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Urine Culture ◽  
Clinical Manifestations ◽  
University Hospital ◽  
E Coli ◽  
Positive Urine ◽  
Tract Infections

Objectives: To investigate clinical characteristics, bacterial characteristics, drug resistance status in patients with urinary tract infections treated at Department of Urology, Hue University Hospital. Materials and Method: The study was conducted in 474 patients with urological disease treated at Department of Urology, Hue Universiry Hospital from July 2017 to April 2018. Urine culture was done in the patients with urine > 25 Leu/ul who have symptoms of urinary tract disease or infection symptoms. Patients with positive urine cultures were analyzed for clinical and bacterial characteristics. Results: 187/474 (39.5%) patients had symptoms associated with urinary tract infections. 85/474 (17.9%) patients were diagnosed with urinary tract infection. The positive urine culture rate was 45.5%. Symptoms of UTI were varied, and no prominent symptoms. E. coli accounts for the highest proportion (46.67%), followed by, Staphycoccus aureus (10.67%), Pseudomonas aeruginsa (8,0%), Streptococcus faecali and Proteus (2.67%). ESBL - producing E. coli was 69.23%, ESBL producing Enterobacter spp was 33.33%. Gram-negative bacteria are susceptible to meropenem, imipenem, amikacin while gram positive are vancomycin-sensitive. Conclusions: Clinical manifestations of urinary tract infections varied and its typical symptoms are unclear. E.coli is a common bacterium (46.67%). Isolated bacteria have a high rate of resistance to some common antibiotics especially the third generation cephalosporins and quinolones. Most bacteria are resistant to multiple antibiotics at the same time. Gram (+) bacteria are susceptible to vancomycin, and gram (-) bacteria are susceptible to cefoxitin, amikacin, and carbapenem. Key words: urinary tract infection

Sign in / Sign up

Export Citation Format

Share Document