scholarly journals The Efficacy of Topical Vitamin C and Microneedling for Photoaging

2021 ◽  
Vol 33 (1) ◽  
pp. 55
Author(s):  
Karina Dyahtantri Pratiwi ◽  
Muhammad Yulianto Listiawan ◽  
Evy Ervianti ◽  
Cita Rosita Sigit Prakoeswa ◽  
Damayanti Damayanti ◽  
...  
Keyword(s):  
Data Analysis ◽  
Vitamin C ◽  
Pore Size ◽  
Clinical Improvement ◽  
Intervention Group ◽  
Skin Aging ◽  
Control Group ◽  
Photoaged Skin ◽  
Significant Difference ◽  
Tyrosinase Enzyme

Background: Photoaging is premature skin aging caused by exposure to ultraviolet (UV) radiation. Vitamin C is an antioxidant that inhibits the tyrosinase enzyme that can reduce pigmentation. Microneedling procedure can improve the penetration of topical vitamin C, and it has skin rejuvenating effects to reduce wrinkles and minimize pore size. Purpose: The main purpose of this study was to evaluate the efficacy of topical vitamin C application after microneedling intervention for the clinical improvement of photoaging. Methods: Twenty-four women with photoaged skin participated in this randomization study, and they were divided into control and intervention groups. Solution of 0.9% NaCl and microneedling were performed to control group, and topical vitamin C and microneedling were performed to intervention group. Three intervention sessions were repeated at a 2 week interval. Signs of photoaging such as pigmentation, wrinkles, and pores were evaluated using Metis DBQ3-1, and the data were obtained numerically. Result: The data analysis revealed a significant improvement in pigmentation in the intervention group compared to control group (p<0.05). Wrinkles and pores evaluation revealed no significant difference between the control and intervention groups. Conclusion: Topical vitamin C after microneedling procedure has provided a significant improvement in pigmentation compared to NaCl 0.9% after microneedling.

scholarly journals The Effect Of Koya Reboned Powder Consumption On Protein Levels Of Pregnant Women In Prevention Of Stunting In Babies

2021 ◽  
Vol 15 (2) ◽  
pp. 109
Author(s):  
Vera Iriani Abdullah
Keyword(s):  
Data Analysis ◽  
Pregnant Women ◽  
Serum Protein ◽  
Intervention Group ◽  
Control Group ◽  
Control Group Design ◽  
Protein Levels ◽  
Significant Difference ◽  
Before And After ◽  
Normally Distributed

Linear growth retardation in childhood has decreased over the past few decades, but has not had a positive effect. In Indonesia, the change in the prevalence of stunting is around 37%. The nutritional status of pregnant women plays an important role in the incidence of stunting, which will be seen at the age of <5 years in 1000 days of their life. Pregnant women with poor nutrition and significant infection can give birth to a baby with stunting. For this reason, nutritional intake is needed, one of the animal foods that are high in protein is rebon shrimp about 62.4 g / 100 grams of dried shrimp. Protein has an important component so it is necessary for the physical development of children. The purpose of this study was to analyze serum protein levels before and after consuming rebon shrimp based PMT powder in the intervention group and control group and to analyze differences in serum protein levels for pregnant women before and after consuming PMT Koya powder made from rebon shrimp between the control and intervention groups. . This type of research is a quantitative study with a quasi-experimental method using the pre post test control group design approach. The number of respondents was 30 people who were divided into 2 groups, namely the intervention group and the control group. The intervention group was given koya powder as much as 100 grams / day for 7 days, assuming the fulfillment of 70 KKal. Data analysis using Data analysis using the Mann-Whitney test, if the data is not normally distributed. If the data are not normally distributed using the free sample t2 test. The conclusion of the analysis results to answer the research hypothesis. The results of the study were significant values P 0.000 <0.05. Conclusion There was a significant difference in serum protein levels of pregnant women before and after consuming PMT Koya powder made from boiled shrimp between the control and intervention groups.

scholarly journals PENGARUH PEMBERIAN TABLET FE + JUS AVOKAD (Persea Americana Mill) TERHADAP KADAR HEMOGLOBIN IBU HAMIL TRIMESTER II DI PMB SURYANI KECAMATAN MEDAN JOHOR TAHUN 2019

2020 ◽  
Vol 1 (2) ◽  
pp. 16-24
Author(s):  
Tri Putri Ageng Utami
Keyword(s):  
Vitamin C ◽  
Pregnant Women ◽  
Intervention Group ◽  
Persea Americana ◽  
Control Group ◽  
Second Trimester ◽  
Control Group Design ◽  
Significant Difference ◽  
Before And After ◽  
Iron Folic Acid

Introduction: Anemia is a biggest health in the world. According to WHO the prevalence of anemia in pregnant women was 41,8%. Based on the results of Riskesdas that the proportion of anemia in pregnant women in 2013 was 37,1% and in 2018 of 48,9%. To prevent anemia, pregnant women are expected to get at least 90 iron tablets during pregnancy and consume iron-rich foods. Avocados have the nutrients of vitamin C, vitamin E, vitamin K, iron, folic acid, potassium, calories and fat. Iron in avocados is useful for the formation of red blood cells, preventing and treating anemia. Vitamin C helps to absorb iron and calcium Methods: This study aims to determine the effect of Fe + avocado juice (Persea Americana Mill) to haemoglobin levels of second trimester pregnant women in Suryani independent clinic of Medan Johor sub district in 2019. This type of research was Quasi Experiment with Pre Test and Post Test With Control Group Design. The population of this research was all 42 pregnant women with 30 purposive sampling techniques. Results and Discussion: Based on the collection and analysis of data with an average result of haemoglobin in second trimester pregnant women increased by 0,87 gr/dl in the intervention group and 0,8 gr/dl in the control group. There are significant differences between before and after treartment in the intervention group and the control group. In the intervention group and the control group before the treatment there can be no difference which means the data is homogeneous and after the treatment there can be no significant difference which means that Ho is accepted and Ha is rejected. Conclusion: Pregnant women who have Hb levels below normal may be given Fe tablets alone or can be combined to consume avocado juice.

scholarly journals Effect of vitamin C on the incidence and severity of postdural puncture headache in patients undergoing cesarean section with spinal anesthesia

2021 ◽  
Vol 43 (1) ◽  
pp. 55-60
Author(s):  
Sepehr Eslami ◽  
Mina Shakeri
Keyword(s):  
Vitamin C ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Normal Saline ◽  
Intervention Group ◽  
Control Group ◽  
Significant Difference ◽  
Group 2 ◽  
Positive Effect ◽  
Group 1

Background: Some studies have shown that vitamin C has a positive effect on reducing headaches after spinal anesthesia, but studies in this field are inadequate. The aim of this study was to determine the effect of vitamin C infusion on the decrease of headache after spinal anesthesia in cesarean section. Methods: This clinical trial study was performed on 160 patients undergoing cesarean section referred to Kowsar Hospital of Yazd in 2017. The patients were randomly divided into two groups including group 1, 2 gr of vitamin C in 500 cc normal saline, and group 2, 500 cc of normal saline was injected preoperatively. The two groups were compared for headache incidence. Results: At the time of recovery, 2 hours later, the frequency of headache in the intervention group was significantly lower than the control group (P <0.05). But there was no significant difference between the two groups regarding headache at 4, 6, 12, 24, and 48 hours postoperatively (P>0.05). Conclusion: Considering the patient's condition, and according to the anesthesiologist and surgeon, vitamin C can be used to reduce pain in patients undergoing cesarean section with spinal anesthesia.

scholarly journals Correlation of Epidermal Fibroblast Growth Factor and Clinical Improvement of Asthma in Children after Zinc Supplementation

2020 ◽  
Vol 6 (3) ◽  
pp. 61
Author(s):  
Retno Asih Setyoningrum ◽  
Anang Endaryanto ◽  
I Dewa Gede Ugrasena
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Clinical Improvement ◽  
Zinc Supplementation ◽  
Intervention Group ◽  
Persistent Asthma ◽  
Control Group ◽  
Fibroblast Growth ◽  
Asthma Control Test ◽  
Significant Difference

Background: Background The presence of remodeling process on the pathogenesis of asthma that involves some growth factors such as epidermal growth factor (EGF) and fibroblast growth factor (FGF) causes the chronicity of the disease. The role of zinc on the pathogenesis of asthma is being widely investigated. This study aimed to analyze the correlation between EGF and FGF2 and clinical improvement of asthma after  zinc supplementation.Methods: A quasi-experimental study was conducted in Outpatient Clinic Dr. Soetomo Hospital. The samples were persistent asthma patients from 6-15 years old who received controller therapy. The samples were divided into 2 groups, those who received zinc supplementation as the intervention group, and who received pacebo as the control. EGF and FGF2 plasma level of both groups were measured, and clinical improvement was evaluated with Childhood Asthma Control Test (C-ACT).Results: There were 11 patients who received zinc supplementation and 12 patients in the control group. There was a significant difference (p = 0.000) on the increase of EGF level in the intervention group (55.59 ± 6.48) than the control (5.35 ± 5.55). There was a significant difference (p = 0.000) on the increase of the FGF2 level in the intervention group (6.37 ± 1.41) than the control (0.72 ± 0.48). The increase of EGF (r = 0.592; p = 0.003) and FGF2 (r = 0.607; p = 0.002) would be followed by the increase of C-ACT scores.Conclusion: Zinc supplementation increase EGF and FGF2 levels. This improvement is correlated with clinical improvement of patients.

Breastfeeding Training through Role-Play and Effects on Mother-infant Attachment Behaviours: A Randomised Controlled Trial

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Farokh Saljughi ◽  
Mitra Savabi-Esfahani ◽  
Shahnaz Kohan ◽  
Soheila Ehsanpour
Keyword(s):  
Pregnant Women ◽  
Maternal Employment ◽  
Controlled Trial ◽  
Role Play ◽  
Intervention Group ◽  
Control Group ◽  
Maternal Behaviour ◽  
Infant Attachment ◽  
Significant Difference ◽  
History Of

Mother-infant attachment is an intimate, lasting and satisfying relationship that leads to better cognitive, emotional and social growth of the infant. The aim of this study was to determine the effects of breastfeeding training by role-play on mother-infant attachment behaviours. This research was a randomised clinical trial (parallel design). Inclusion criteria were: no history of mental disorders; ability to read and write the Persian language to complete the questionnaire; no history of drug and tobacco intake in primigravida women. The sample comprised 100 pregnant women (in 2 groups), selected through simple random sampling at healthcare centres. The researcher reviewed prenatal care registries of selected healthcare centres and extracted the names of pregnant women in their early third trimester. The data were imported into randomisation software. The control group received routine breastfeeding training, while the intervention group received routine training together with training through role-play. The data collection tool was the Maternal Behaviour Inventory Questionnaire. Consequently 75 samples were analysed in SPSS16. Independent t-tests and chi-square tests were used to examine the difference between the two groups. Results showed that the mean score of mother-infant attachment one week after delivery was significantly higher in the intervention group in comparison to that in the control group (p<0.001). No significant difference was observed between the two groups in maternal age, age of marriage, neonatal gender, maternal employment and education, number of parity, and number of abortions (P>0.05). Since breastfeeding training through role-play could affect mother-infant attachment, it is suggested that this type of training should be provided for pregnant women to promote mother-infant attachment and exclusive breastfeeding.

TERAPI MUSIK DAN TINGKAT KECEMASAN PASIEN PREOPERASI

2016 ◽  
Vol 5 (1) ◽  
pp. 1-6
Author(s):  
Wenny Savitri ◽  
Nani Fidayanti ◽  
Paulus Subiyanto
Keyword(s):  
Music Therapy ◽  
Intervention Group ◽  
Complementary Therapy ◽  
T Test ◽  
Anxiety Level ◽  
Preoperative Anxiety ◽  
Control Group ◽  
Music Intervention ◽  
Significant Difference ◽  
Anxiety Levels

Background: Surgery is one of medical interventions which can cause fear, anxiety, and stressed because of its effects toward the integrity of body and soul. Nurses have significant roles in any preoperative care which is helping patients to decrease preoperative anxiety by using complementary therapy. The use of music therapy as one of the complementary therapies is not common in Indonesia. Therefore, scientific studies to prove the role of this therapy to decrease the level of anxiety of pre-operative patients is needed. Objective: To investigate the effects of music therapy in reducing anxiety levels of preoperative patients. Methods: A quasy experimental study with pre-test and post-test design with control group was applied to 50 respondents from medical ward in Panembahan Senopati Hospital of Yogyakarta who met the inclusion criteria.Dara were then analyzed by using t-test statistical analysis. Results: The control group showed the increased value of anxiety level of0.8 without music intervention (t= - 1503, df = 24, p<.05), whereas the intervention group showed the decreased value of anxiety level of -5.52 (t=5.081, df=24, p<.05). Meanwhile the independent t-test results for both groups showed a significant difference between group (t= 3,373, df=48, p<.05). Conclusion: Music therapy has significant effect in reducing preoperative anxiety levels of patients. Keywords: anxiety, preoperative, music therapy

The Effect of Reflexology on Labor Pain and Length Among Primiparous Women: A Randomized Controlled Trial

2018 ◽  
Vol 7 ◽  
Author(s):  
Azita Kamjoo
Keyword(s):  
Controlled Trial ◽  
Intervention Group ◽  
Active Phase ◽  
Labor Pain ◽  
Control Group ◽  
Singleton Pregnancy ◽  
Group Data ◽  
Significant Difference ◽  
Labor Length ◽  
Primiparous Women

Background: Pain control is considered as the key issue in modern midwifery. Along with medical painkillers, reflexology is viewed as a non-medical and noninvasive method. Hence, we aimed to investigate the effect of reflexology on the intensity of pain and length of labor. Materials and Methods: In this clinical trial, participants included 240 Iranian primiparous women with term and singleton pregnancy. Having a 3-4 cm cervical dilatation once they visited the hospital. Through a convenient sampling method, they were selected and then randomly divided into two groups. In the intervention group, reflexology was performed, and the intensity of pain during the active phase of labor along with the length of labor in the active phase was measured by visual analog scale (VAS) and compared with the control group. Data were analyzed using descriptive statistics, t-test, and Mann-Whitney U-test. Result: Data analysis showed a statistically significant difference between the intensity of pain in the 5-7 and 8-10 cm dilatation in the two groups (P=0.01). Moreover, the labor length in the active phase was found to be significantly shorter in the intervention group (P<0.001). Conclusion: It appears that reflexology can lead to a reduction in the pain and length of labor. Therefore, through instructing this technique, a goal of midwifery, which is reducing labor pain and its length can be achieved. Keywords: Reflexology, Labor Pain, Labor Length, Primiparous Women

The Effectiveness of Using a Mobile Messenger as an Educational Supporting Tool among Nursing Students

2020 ◽  
Vol 4 (1) ◽  
pp. 67-77
Author(s):  
Rohimah Ismail ◽  
Chong Mei Chan ◽  
Wan Muhammad Azly W. Zulkafli ◽  
Hasnah Zani ◽  
Zainab Mohd Shafie
Keyword(s):  
Nursing Education ◽  
Nursing Students ◽  
Clinical Decision Making ◽  
Intervention Group ◽  
Great Influence ◽  
Control Group ◽  
P Value ◽  
Significant Difference ◽  
Supporting Tool ◽  
Nursing College

                The evolution of information technology has exerted great influence on nursing education via new pedagogy of knowledge delivery without time and place restriction. Mobile technology revolutionises nursing education and clinical practice via empowering skills of critical thinking and clinical decision-making through learning. The aim of this study is to evaluate the effectiveness of using mobile messenger (Whatsapp) as an educational supporting tool among nursing students. The study design used is a Cluster Randomized Control Trail. Two nursing colleges were selected. Sample size was 93 participants, 48 from the Kuala Terengganu Nursing College Kuala Terengganu as the intervention group while the control group were recruited among 45 participants from UniSZA Nursing College. There is a significant difference in the level of knowledge between pre and posttest among intervention group (mean difference was -8.70 with a standard deviation 8.42, p-value< 0.001) and 93.8 percent of the respondents perceived the usefulness of using WhatsApp mobile messenger to enhance learning. This demonstrates that learning through mobile messenger (WhatsApp) enhances learning and is well received as a new method of learning by almost all students.   Keywords: Mobile learning, WhatsApp messenger, Social Interaction

Comparison of the Effects of Fenugreek Vaginal Cream and Ultra Low- Dose Estrogen on Atrophic Vaginitis

2020 ◽  
Vol 17 (9) ◽  
pp. 815-822
Author(s):  
Maryam Safary ◽  
Sevil Hakimi ◽  
Noushin Mobaraki-Asl ◽  
Paria Amiri ◽  
Habib Tvassoli ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Low Dose ◽  
Intervention Group ◽  
Clinical Signs ◽  
Control Group ◽  
Conjugated Estrogens ◽  
Atrophic Vaginitis ◽  
Vaginal Cream ◽  
Intergroup Comparison ◽  
Significant Difference

Introduction: Atrophic vaginitis is a common problem in postmenopausal women and results from decreased levels of blood estrogen. It is associated with symptoms of itching, burning, dyspareunia, and postmenopausal bleeding. The present study evaluated the effects of fenugreek extract on atrophic vaginitis. Materials and Methods: This randomized controlled clinical trial was performed on 60 postmenopausal women in Ardabil, Iran, in 2018. The participants were selected using block randomization with the allocation ratio 1:1. Those in the intervention group received 0.5g (the applicator filled to the half-full mark) fenugreek vaginal cream 5% twice a week for 12 weeks. The control group received conjugated estrogens vaginal cream at the dose of 0.625 mg (the applicator filled to the half-full mark) containing 0.3 mg of conjugated estrogens. Atrophic vaginitis was evaluated before and after the treatment through clinical examination, clinical signs, and measurement of Vaginal Maturation Index (VMI). Findings: After the 12-week intervention and modification of the baseline score, the mean (standard error) score for atrophic vaginitis signs was 3.100 (1.43-4.75). This difference was statistically significant in intragroup comparison and in favor of the control group in intergroup comparison (p=0.001). VMI was less than 49% in 86.7% and 46.7% of the participants in the intervention and control groups, respectively. This was a significant difference in favor of the control group (p=0.001). Conclusion: The results of this study showed that total fenugreek extract could be effective in treating signs of atrophic vaginitis, but it was not as effective as ultra-low-dose estrogen.

Efficacy of Aloe vera/ Plantago Major Gel in Diabetic Foot Ulcer: A Randomized Double-Blind Clinical Trial

2019 ◽  
Vol 16 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Younes Najafian ◽  
Zahra M. Khorasani ◽  
Mona N. Najafi ◽  
Shokouh S. Hamedi ◽  
Marjan Mahjour ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Diabetic Foot ◽  
Intervention Group ◽  
Aloe Vera ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Control Group ◽  
Plantago Major ◽  
Double Blind ◽  
Significant Difference

Background:Diabetic foot ulcer (DFU) is one of the most common complications of diabetic patients. Mostly, non-healing DFU leads to infection, gangrene, amputation and even death. High costs and poor healing of the wounds need a new treatment such as alternative medicine. So, the aim of this study was to evaluate the efficacy of Aloe vera/ Plantago major gel (Plantavera gel) in healing of DFUMethods:Forty patients with DFU enrolled in a double-blind randomized clinical trial. The patients who were randomly assigned into the intervention group (n = 20), received topical Plantavera gel in addition to the routine cares, whereas the patients in the control group (n = 20), received topical Placebo gel in addition to the routine cares. Intervention was done twice a day for 4 weeks in the both groups. Photography and an evaluation of DFU healing were conducted by a checklist and then were scored at baseline and at the end of each week. The collected data was analyzed by SPSS software.Results:At the end of the study, there was a significant difference between the two groups in terms of total ulcer score (P<0.001) and Plantavera gel significantly reduced the ulcer surface comparing with the control group (P=0.039). However, there was not a significant difference between the two groups (P=0.263) in terms of the ulcer depth. During this study, no side effect was observed for Plantavera gel in the intervention group.Conclusion:Topical Plantavera gel seems to be an effective, cheap and safe treatment. Of course, further studies are required to confirm the properties of the wound healing of this gel.

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