scholarly journals Efektivitas Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi Linn) sebagai Bahan Pembersih Saluran Akar Gigi (The Effectiveness of Wuluh Starfruit (Averrhoa bilimbi Linn) Leaf Extract as Root Canal Cleaner)

2016 ◽  
Vol 6 (2) ◽  
pp. 82
Author(s):  
Amalia Dara N ◽  
Ira Widjiastuti ◽  
Laksmiari Setyowati

Background: Preparation is one of the stages in endodontic treatment that always produce debris as a result of intrumentation on root canal walls. Debris consist of organic and inorganic materials. Debris will impede the penetration of disinfection materials and reduce attachment of the root canal filling material, therefore needed root canal irrigant which can remove the debris. Wuluh starfruit leaf extract (Averrhoa bilimbi Linn) contain various active compound, such as saponin. Saponin act as “surfactants” which can remove the debris. Purpose: This study was to determine the cleaning effectiveness concentration of wuluh starfruit leaf extract which can clean the root canal walls from debris. Method: Twenty five first premolar human teeth with straight single roots were randomized into five groups in which each group consist of five teeth. Those teeth instrumented with K-file and irrigated as follows: Group 1 (control) used aquadest as irrigant, group 2 used extract 5%, group 3 used extract 10%, group 4 used extract 15%, and group 5 used extract 20%. Then, those teeth were split horizontally and longitudinally in 1/3 apex. After that, the apical third of root canal walls were observed by using scanning electron microscope (SEM). Result: There were significant differences between each group (p<0,05). Group 4 and 5 had smallest median score that was 1. Saponin in wuluh star fruit leaf extract 15% has been reach critical micelle concentration (CMC). Conclusion: Wuluh starfruit leaf extract 15% effective for cleaning root canal walls from debris.

2014 ◽  
Vol 08 (01) ◽  
pp. 032-037 ◽  
Author(s):  
Ali Keles ◽  
Fuat Ahmetoglu ◽  
Mevlut S. Ocak ◽  
Burak Dayi ◽  
Alperen Bozkurt ◽  
...  

ABSTRACT Objectives: The aim of this study was to evaluate the sealing abilities of three different gutta-percha techniques in experimentally defective roots (EDR) and non-defective roots (NR). Materials and Methods: Sixty canine teeth were divided into six groups of ten; Group 1, NR + cold lateral condensation (CLC); Group 2, EDR + LC; Group 3, NR + BeeFill; Group 4, EDR + BeeFill; Group 5, NR + Thermafil; and Group 6, EDR + Thermafil. Apical leakage was measured using a computerized fluid filtration meter with a laser system. Results: Statistical analysis revealed that the CLC demonstrated more microleakage in the EDR than in the NR (P < 0.01). Thermafil demonstrated more microleakage in the NR than in the EDR (P < 0.01). No statistically significant differences were found between the BeeFill groups (P > 0.05). Conclusions: The results of this study indicate that internal resorptive cavities can affect the apical sealing properties of different root canal filling techniques, with Thermafil ensuring the lowest apical microleakage.


2015 ◽  
Vol 09 (03) ◽  
pp. 378-381
Author(s):  
Tugba Turk ◽  
Beyser Piskin ◽  
Hasan Orucoglu ◽  
Berdan Aydin

ABSTRACT Objectives: To evaluate the effect of spreader size on apical leakage of maxillary incisor teeth. Materials and Methods: A total of 75 permanent human teeth with no carious and no fracture or crack were used for this study. After removing the crown from the cementoenamel junction and the standardization of the root lengths, the specimens were randomly divided into five groups: Group 1 - Roots were not instrumented. Group 2 - Root canals were enlarged using the step-back technique to a #40 file and filled using cold lateral compaction (CLC) of gutta-percha (GP). Group 3 - During the filling procedure, the first spreader used was size 40. Group 4 - The first spreader used was size 35. Group 5 - The initial spreader used was size 25. The amount of leakage through the filled root canals was evaluated by computerized fluid filtration model. Statistical analyzes were done using Kruskal–Wallis test and Mann–Whitney test (P < 0.05). Results: There were statistically significant differences among the groups (P < 0.05). While the uninstrumented group (Group 1) had no leakage, instrumented but not filled roots (Group 2) demonstrated the highest leakage values. There were no differences between Group 3 and 4. Group 5 showed significantly less leakage than Group 3 and 4. Conclusion: Spreader size used during CLC of GP appeared to be a significant factor on apical leakage of roots. Using smaller size spreader during CLC may provide relatively less leakage.


2019 ◽  
Vol 9 (1) ◽  
pp. 1-8
Author(s):  
Selen İnce Yusufoğlu ◽  
Hale Arı Aydınbelge

Aim: The purpose of the present study was to compare the cleaning effectiveness of two reciprocating single-file systems with ProTaper Next and ProTaper Universal rotary instruments during the preparation of single-rooted extracted teeth. Methodology: Sixty freshly extracted single-rooted human teeth were randomly divided into 4 groups (n=15). In group 1, root canals were prepared with ProTaper Universal, in group 2, they were prepared with ProTaper Next, in group 3, they were prepared with WaveOne and in group 4, root canals prepared with Reciproc systems. Canals were prepared to the following apical sizes: ProTaper Universal F3, ProTaper Next X3, WaveOne Primary and Reciproc 25. The irrigant in all groups was 2ml 2.5% sodium hypochlorite (NaOCl) solution, the final irrigation after preparation all groups was 2ml NaOCl, 2ml EDTA and 2ml saline solution. The roots were split longitudinally into halves and the canals examined using a scanning electron microscope. The presence of a debris and smear layer was recorded at the coronal, middle and the apical thirds of root canals using a five-step scoring scale. Data were statistically analyzed using Kruskal-Wallis and Mann-Whitney U tests. Results: All groups showed more efficient smear layer and debris removal coronally than in the middle and apical regions, whereas the mean total debris score and the mean smear layer score in all groups were less in the WaveOne and the Reciproc groups. Conclusions: Under the conditions of this study, for root canal cleanliness Reciproc and WaveOne may be preferred rather than ProTaperUniversal and ProTaperNext.   How to cite this article: İnce Yusufoğlu S, Arı Aydınbelge H. Root canal cleaning with different reciprocating and rotary instrumentation systems. Int Dent Res 2019;9(1):1-8.   Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.


Author(s):  
P. Bagavandoss ◽  
JoAnne S. Richards ◽  
A. Rees Midgley

During follicular development in the mammalian ovary, several functional changes occur in the granulosa cells in response to steroid hormones and gonadotropins (1,2). In particular, marked changes in the content of membrane-associated receptors for the gonadotropins have been observed (1).We report here scanning electron microscope observations of morphological changes that occur on the granulosa cell surface in response to the administration of estradiol, human follicle stimulating hormone (hFSH), and human chorionic gonadotropin (hCG).Immature female rats that were hypophysectcmized on day 24 of age were treated in the following manner. Group 1: control groups were injected once a day with 0.1 ml phosphate buffered saline (PBS) for 3 days; group 2: estradiol (1.5 mg/0.2 ml propylene glycol) once a day for 3 days; group 3: estradiol for 3 days followed by 2 days of hFSH (1 μg/0.1 ml) twice daily, group 4: same as in group 3; group 5: same as in group 3 with a final injection of hCG (5 IU/0.1 ml) on the fifth day.


2019 ◽  
Vol 17 (4) ◽  
pp. 354-364
Author(s):  
Hassan Al-Thani ◽  
Moamena El-Matbouly ◽  
Maryam Al-Sulaiti ◽  
Noora Al-Thani ◽  
Mohammad Asim ◽  
...  

Background: We hypothesized that perioperative HbA1c influenced the pattern and outcomes of Lower Extremity Amputation (LEA). Methods: A retrospective analysis was conducted for all patients who underwent LEA between 2000 and 2013. Patients were categorized into 5 groups according to their perioperative HbA1c values [Group 1 (<6.5%), Group 2 (6.5-7.4%), Group 3 (7.5-8.4%), Group 4 (8.5-9.4%) and Group 5 (≥9.5%)]. We identified 848 patients with LEA; perioperative HbA1c levels were available in 547 cases (Group 1: 18.8%, Group 2: 17.7%, Group 3: 15.0%, Group 4: 13.5% and Group 5: 34.9%). Major amputation was performed in 35%, 32%, 22%, 10.8% and 13.6%, respectively. Results: The overall mortality was 36.5%; of that one quarter occurred during the index hospitalization. Mortality was higher in Group 1 (57.4%) compared with Groups 2-5 (46.9%, 38.3%, 36.1% and 31.2%, respectively, p=0.001). Cox regression analysis showed that poor glycemic control (Group 4 and 5) had lower risk of mortality post-LEA [hazard ratio 0.57 (95% CI 0.35-0.93) and hazard ratio 0.46 (95% CI 0.31-0.69)]; this mortality risk persisted even after adjustment for age and sex but was statistically insignificant. The rate of LEA was greater among poor glycemic control patients; however, the mortality was higher among patients with tight control. Conclusion: The effects of HbA1c on the immediate and long-term LEA outcomes and its therapeutic implications need further investigation.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yu Liu ◽  
Jing Li ◽  
Wanyu Zhang ◽  
Yihong Guo

AbstractOestradiol, an important hormone in follicular development and endometrial receptivity, is closely related to clinical outcomes of fresh in vitro fertilization-embryo transfer (IVF-ET) cycles. A supraphysiologic E2 level is inevitable during controlled ovarian hyper-stimulation (COH), and its effect on the outcome of IVF-ET is controversial. The aim of this retrospective study is to evaluate the association between elevated serum oestradiol (E2) levels on the day of human chorionic gonadotrophin (hCG) administration and neonatal birthweight after IVF-ET cycles. The data of 3659 infertile patients with fresh IVF-ET cycles were analysed retrospectively between August 2009 and February 2017 in First Hospital of Zhengzhou University. Patients were categorized by serum E2 levels on the day of hCG administration into six groups: group 1 (serum E2 levels ≤ 1000 pg/mL, n = 230), group 2 (serum E2 levels between 1001 and 2000 pg/mL, n = 524), group 3 (serum E2 levels between 2001 and 3000 pg/mL, n = 783), group 4 (serum E2 levels between 3001 and 4000 pg/mL, n = 721), group 5 (serum E2 levels between 4001 and 5000 pg/mL, n = 548 ), and group 6 (serum E2 levels > 5000 pg/mL, n = 852). Univariate linear regression was used to evaluate the independent correlation between each factor and outcome index. Multiple logistic regression was used to adjust for confounding factors. The LBW rates were as follows: 3.0% (group 1), 2.9% (group 2), 1.9% (group 3), 2.9% (group 4), 2.9% (group 5), and 2.0% (group 6) (P = 0.629), respectively. There were no statistically significant differences in the incidences of neonatal LBW among the six groups. We did not detect an association between peak serum E2 level during ovarian stimulation and neonatal birthweight after IVF-ET. The results of this retrospective cohort study showed that serum E2 peak levels during ovarian stimulation were not associated with birth weight during IVF cycles. In addition, no association was found between higher E2 levels and increased LBW risk. Our observations suggest that the hyper-oestrogenic milieu during COS does not seem to have adverse effects on the birthweight of offspring after IVF. Although this study provides some reference, the obstetric-related factors were not included due to historical reasons. The impact of the high estrogen environment during COS on the birth weight of IVF offspring still needs future research.


1997 ◽  
Vol 65 (2) ◽  
pp. 267-273 ◽  
Author(s):  
I. A. Forsyth ◽  
F. E. Gebbie ◽  
J. Arendt

AbstractTo avoid winter scarcity of fresh goat milk, simple methods of advancing the season of kidding would be commercially valuable. A combination of long-day light treatment followed by melatonin is successful but other aspects of seasonality including coat growth are also reset. To investigate whether effects on breeding season and coat growth can be dissociated, British Saanen dairy goats (no. = 30) were randomly allocated to one of six groups. Control goats were untreated. Goats in the other five groups received 2 months of treatment with 20 h light: 4 h darkness (20L: 4D) and were then given 3 mg melatonin orally at 16.00 hfor 2 months. The treatments started on 11 January (group 1), 29 March (group 2), 14 June (group 3), 30 August (group 4) and 8 November (group 5). Weekly blood samples were taken for the measurement of progesterone to monitor ovarian activity and prolactin. Side patches (10 cm ×10 cm) were clipped monthly from alternate sides and weighed to measure coat growth. The onset of ovarian activity was advanced from a median date of 15 November in controls to 24 May in group 1 (P < 0·01), 16 August in group 2 (P < 0·05) and 18 October in group 3 (? < 0·05). Groups 4 and 5 showed no significant change in the onset of oestrus (median onset dates 8 November and 1 November, respectively). Group 1 goats came into season again with controls in November. In all except group 5, treatment interacted with time to affect significantly the growth of the coat. The pattern of coat growth was most altered (P < 0·001) in groups 1 and 2. This was associated with effects on plasma prolactin concentrations of light stimulation and melatonin suppression. Group 1 goats resynchronized with control goats to show a coat of normal weight in the winter following treatment. Division of milking goat herds into spring and autumn kidding groups is, therefore, a practical possibility, but effects on overall milk yield require study.


1984 ◽  
Vol 64 (1) ◽  
pp. 39-43 ◽  
Author(s):  
L. E. JEREMIAH ◽  
G. M. WEISS

A total of 130 barrows and 113 gilts were slaughtered over a range of liveweights from 65.6 to 143.9 kg. These animals were randomly assigned to six different liveweight groups (group 1, less than 79.5 kg; group 2, 79.5 through 93.1 kg; group 3, 93.2 through 106.7 kg; group 4, 106.8 through 120.4 kg; group 5, 120.5 through 134.0 kg; and group 6, 134.1 kg and over) and utilized to evaluate the effects of slaughter weight and sex on palatability and cooking properties. The composite results indicated that the slaughter weight of both barrows and gilts can, from a practical standpoint, be increased to take advantage of potential economic advantages without meaningfully altering cooking losses or palatability attributes. Key words: Pork, slaughter weight, sex, palatability, cooking losses


Kavkazologiya ◽  
2021 ◽  
pp. 12-25
Author(s):  
S.M. OSTASHINSKIJ ◽  
◽  
M.A. KULKOVA ◽  

The article presents the results of petrographic analysis of the ceramics of the Chalcolithic settlement of Meshoko. A total of 42 fragments were examined (see appendix), 10 of which belong to the upper part of the monument's sediments (layers 1 and 2a; Fig. 1), 20 refer to the middle part of the sediments (layer 2b; Fig. 2), 12 – to the lower part (layer 3; Fig. 3). Based on the analysis, 5 groups of ceramics were identified (Fig. 4). Group 1 consists of fragments with an admixture of limestone, group 2 – with an admixture of diorite, group 3 – with an admixture of biogenic carbonates and sand, group 4 – with an admixture of calcite, group 5 – with an admixture of diorite and chamotte. Clays of smectite composition predominate in groups 1 and 2, while clays of smectite-carbonate composition predominate in groups 3 and 4. Comparison of these groups with stratigraphy revealed that most of the ceramics of groups 3 and 4 are confined to the lower layer, and groups 1 and 2 to the middle and upper layer (Table 1). In addition, the ceramics of these layers differ in the nature of the external surface treatment. Significant changes in the technology of making ceramics during the transition from the lower layer to the middle layer allow us to assume corresponding changes in the composition of the population.


2007 ◽  
Vol 18 (1) ◽  
pp. 20-23 ◽  
Author(s):  
João Vicente Baroni Barbizam ◽  
Matheus Souza ◽  
Doglas Cecchin ◽  
Jakob Dabbel

The purpose of this in vitro study was to evaluate the ability of a silicon-based root canal sealer, compared to zinc oxide and eugenol and an epoxy resin-based sealers, for filling of simulated lateral canals. Thirty extracted single-rooted human teeth were selected, conventional access was made and the working length was established 1 mm from the apical foramen. Three simulated lateral canals, one in each root third (coronal, middle and apical) were prepared in both the mesial and distal surfaces of each tooth using a size 15 reamer adapted to a low-speed handpiece. Each root canal was instrumented using ProTaper rotary files up to file F3 at the working length, and then irrigated with 2.5% NaOCl followed by EDTA. The teeth were assigned to 3 groups (n=10), according to the root canal sealer: Roeko Seal (Group 1), Sealer 26 (group 2) and Grossman's sealer (Group 3). Gutta-percha cold lateral condensation technique was performed in all groups. Postoperative radiographs were taken and the images were projected for evaluation of the quality of lateral canal filling. Data were submitted to statistical analysis by Kruskal Wallis test at 5% significance level. The results showed that Grossman's sealer filled a larger number of lateral canals than Roeko Seal (p<0.05) and Sealer 26 (p<0.01). It may be concluded that Roeko Seal silicone-based root canal sealer was not as effective as the Grossman's sealer for filling of simulated lateral canals. The lateral canals localized in the apical third of the root were more difficult to be filled.


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