scholarly journals EFFECTIVENESS AND SAFETY DIFFERENCES OF ISOXSUPRINE AND NIFEDIPINE AS TOCOLYTICS IN THE RISK OF PRETERM LABOR

2017 ◽  
Vol 53 (4) ◽  
pp. 242
Author(s):  
Nur Oktavia ◽  
Yulistiani Yulistiani ◽  
Unedo H Markus ◽  
Hendriette Irene Mamo

Premature labor is a cause of high rates of perinatal morbidity and mortality. The use of tocolytics is one of the efforts to handle the risk of preterm labor. Tocolytics which are widely used in Indonesia is isoxsuprine and nifedipine. The purpose of this study was to identify the difference of effectiveness and safety of isoxsuprine as tocolytics in the risk of preterm labor. This was an observational study in the form of a case study that was done in detail and depth to the patients who were diagnosed as imminent preterm labor. In conclusion, there were differences in the effectiveness and safety of isoxsuprine and nifedipine as tocolytics in the risk of preterm labor.

1999 ◽  
Vol 48 (2) ◽  
pp. 22-26
Author(s):  
M. A. Repina ◽  
N. V. Kulagina ◽  
Ya. A. Kornilova

In modern obstetrics there is an urgent problem of treatment of threat of premature labor being one of the basic reasons for perinatal losses. In the article the prospects of Gynipral application in pregnant women, and also the results of practical application of a drug in clinic are considered. It is proved, that the application of beta-adrenomimetic Gynipral allows effectively and without development of complications on the part of the mother to carry out the treatment of premature labor threat, hypoxia a fetus, discoordination in labor, that provides the perinatal morbidity and mortality reduction.


Author(s):  
Maunica Reddy Sorakayalapeta ◽  
Nandish S. Manoli

Background: 2-5% of the pregnancies are complicated by antepartum haemorrhage. About one third of them are due to placenta previa thus contributing to a significant amount of maternal and perinatal morbidity and mortality. In the present times with liberally increasing caesarean section rates, there is a changing trend in the incidence and complications of placenta previa. The objective of this study was to evaluate the obstetrical characteristics and maternal and perinatal outcome of cases of placenta previa.Methods: This was a prospective observational study conducted in the Department of Obstetrics and Gynaecology of JSS Medical College and Hospital, Mysore during the period January 2017 to June 2018.Results: Out of total 13,150 deliveries during this period, placenta previa was observed in 131 cases with an incidence of 1%. Majority belonged to the age group 25-29 years (48.8%). 66% of the cases presented with painless vaginal bleeding as their chief complaint. The major risk factor was previous caesarean delivery seen in 29.8% cases followed by history of abortion in 18.3%. 67% cases had major degree placenta previa. Remaining 33% cases had minor degree. One case was complicated by placenta accrete. Peripartum hysterectomy was performed in 3.1%. Preterm deliveries amounted to 29.8%. Maternal and perinatal mortality were 0.76% and 3.05% respectively. 10.7% cases had Postpartum haemorrhage and 3.8% required ICU admission. 25% neonates required NICU admissions and 10% had RDS.Conclusions: Placenta previa is a prime contributor to substantial maternal and perinatal morbidity and mortality. Early referral to tertiary care centres, anticipation of clinical complications and appropriate measures can avoid grave consequences. Such cases must always be managed at a higher centre with good NICU services and round the clock operation theatre and blood bank facility.


2021 ◽  
pp. 1-8
Author(s):  
Alfredo Leaños-Miranda ◽  
Ana Graciela Nolasco-Leaños ◽  
Reyes Ismael Carrillo-Juárez ◽  
Carlos José Molina-Pérez ◽  
Irma Isordia-Salas ◽  
...  

<b><i>Introduction:</i></b> Amniotic fluid (AF) interleukin-6 (IL-6) concentration has been associated to preterm delivery and perinatal morbidity and mortality in women with preterm labor and intact membranes. Nevertheless, the clinical significance of this biomarker of intra-amniotic inflammation (IAI) is still unclear due in part to the paucity of large studies. <b><i>Methods:</i></b> AF IL-6 concentrations were determined in 452 consecutive women with preterm labor and intact membranes, categorized into 3 groups: 302 without IAI (IL-6 of &#x3c;2.6 ng/mL), 64 with mild IAI (IL-6 of 2.6–11.2 ng/mL), and 86 with severe IAI (IL-6 of ≥11.3 ng/mL). <b><i>Results:</i></b> The severe IAI group had a short pregnancy duration from amniocentesis to delivery (median 3 days) than in without IAI group (median 45 days); meanwhile, the mild IAI group had a latency that was intermediate to the severe and without IAI groups (median 9.5 days). As compared to women without IAI, women with mild and severe IAI had higher rates of preterm delivery at both &#x3c;34 and &#x3c;37 weeks of gestation and perinatal morbidity and mortality. Furthermore, the risk of various individual adverse outcomes (short latency from amniocentesis to delivery [at ≤3 days, ≤7 days, and ≤14 days], preterm delivery at both &#x3c;34 and &#x3c;37 weeks of gestation, histologic chorioamnionitis, respiratory distress syndrome, and congenital sepsis) was higher in women with severe IAI (OR ≥ 2.8), compared with women without IAI. <b><i>Conclusions:</i></b> AF IL-6 concentrations appear to be suitable marker to assess the degree of IAI and are associated with increased risk of adverse outcomes.


Author(s):  
Santosh Kumari ◽  
Bhal Singh

Background: Placenta previa is an important cause of maternal and fetal morbidity and mortality and is on forefront in deadly triad for maternal mortality followed by eclampsia and sepsis in India. To determine the incidence, maternal and perinatal outcomes among women with placenta previa.Methods: This is a prospective observational study carried out at in the Department of Obstetrics and Gynaecology of a tertiary care hospital of Northern India for a period of six months between Feb 2018 to July 2018.Results: Total number of patients delivered during this period was 6840 and out of which 35 patients were diagnosed with placenta previa, so the incidence is 0.51%. Incidence of placenta previa was the highest in the maternal age group 20-30 years i.e. 71.42%. Placenta previa was noticed in 17.14% of the women with previous cesarean section. Caesarean hysterectomy was performed in 2.85%, 11.42% of the women had postpartum haemorrhage. Perinatal morbidity was studied as the percentage of babies requiring resuscitation and NICU admission which was 25.71 %. There was 19.99 % perinatal mortality.Conclusions: Placenta previa is a major cause of maternal and perinatal morbidity and mortality which could be prevented by early registration, regular antenatal care, early detection of high-risk cases, and early referral to higher centre with good NICU services and blood bank facility.


2014 ◽  
Vol 68 (2) ◽  
pp. 104-106
Author(s):  
Aleksandra Pivkova Veljanovska ◽  
Sonja Genadieva Stavrik ◽  
Zlate Stojanoski ◽  
Lazar Cadievski ◽  
Adela Stefanija ◽  
...  

Abstract The article presents a case with diagnosed Hodgkin disease (HD) during pregnancy. The aim of this case study was to present diagnostic possibilities in determining HD stage during pregnancy and therapeutic dilemmas. The incidence of HD during pregnancy is 3.2% of all cases with this malignant hematological disorder. The treatment of this disease during pregnancy depends on disease-related factors, pregnancy-related factors, as well as possible implications for fetal morbidity and mortality. The need of analysis of the nature of the disease during pregnancy indicates examination of a larger series of pregnant women with HD and the drawn conclusions affect the decision whether chemotherapy treatment should start immediately or it should be postponed for after delivery.


2019 ◽  
Vol 19 (2) ◽  
pp. 101-110
Author(s):  
Adrian Firdaus ◽  
M. Dwi Yoga Sutanto ◽  
Rajin Sihombing ◽  
M. Weldy Hermawan

Abstract Every port in Indonesia must have a Port Master Plan that contains an integrated port development plan. This study discusses one important aspect in the preparation of the Port Master Plan, namely the projected movement of goods and passengers, which can be used as a reference in determining the need for facilities at each stage of port development. The case study was conducted at a port located in a district in Maluku Province and aims to evaluate the analysis of projected demand for goods and passengers occurring at the port. The projection method used is time series and econometric projection. The projection results are then compared with the existing data in 2018. The results of this study show that the econometric projection gives adequate results in predicting loading and unloading activities as well as the number of passenger arrival and departure in 2018. This is indicated by the difference in the percentage of projection results towards the existing data, which is smaller than 10%. Whereas for loading and unloading activities, time series projections with logarithmic trends give better results than econometric projections. Keywords: port, port master plan, port development, unloading activities  Abstrak Setiap pelabuhan di Indonesia harus memiliki sebuah Rencana Induk Pelabuhan yang memuat rencana pengem-bangan pelabuhan secara terpadu. Studi ini membahas salah satu aspek penting dalam penyusunan Rencana Induk Pelabuhan, yaitu proyeksi pergerakan barang dan penumpang, yang dapat dipakai sebagai acuan dalam penentuan kebutuhan fasilitas di setiap tahap pengembangan pelabuhan. Studi kasus dilakukan pada sebuah pelabuhan yang terletak di sebuah kabupaten di Provinsi Maluku dan bertujuan untuk melakukan evaluasi ter-hadap analisis proyeksi demand barang dan penumpang yang terjadi di pelabuhan tersebut. Metode proyeksi yang dipakai adalah proyeksi deret waktu dan ekonometrik. Hasil proyeksi selanjutnya dibandingkan dengan data eksisting tahun 2018. Hasil studi ini menunjukkan bahwa proyeksi ekonometrik memberikan hasil yang cukup baik dalam memprediksi aktivitas bongkar barang serta jumlah penumpang naik dan turun di tahun 2018. Hal ini diindikasikan dengan selisih persentase hasil proyeksi terhadap data eksisting yang lebih kecil dari 10%. Sedangkan untuk aktivitas muat barang, proyeksi deret waktu dengan tren logaritmik memberikan hasil yang lebih baik daripada proyeksi ekonometrik. Kata-kata kunci: pelabuhan, rencana induk pelabuhan, pengembangan pelauhan, aktivitas bongkar barang


2018 ◽  
Vol 32 (19) ◽  
pp. 3278-3287 ◽  
Author(s):  
Limor Besser ◽  
Liat Sabag-Shaviv ◽  
Maayan Yitshak-Sade ◽  
Salvatore Andrea Mastrolia ◽  
Danielle Landau ◽  
...  

2021 ◽  
Vol 11 (9) ◽  
pp. 4121
Author(s):  
Hana Tomaskova ◽  
Erfan Babaee Tirkolaee

The purpose of this article was to demonstrate the difference between a pandemic plan’s textual prescription and its effective processing using graphical notation. Before creating a case study of the Business Process Model and Notation (BPMN) of the Czech Republic’s pandemic plan, we conducted a systematic review of the process approach in pandemic planning and a document analysis of relevant public documents. The authors emphasized the opacity of hundreds of pages of text records in an explanatory case study and demonstrated the effectiveness of the process approach in reengineering and improving the response to such a critical situation. A potential extension to the automation and involvement of SMART technologies or process optimization through process mining techniques is presented as a future research topic.


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