scholarly journals The clinical experience of Gynipral application in pregnant and during labor

1999 ◽  
Vol 48 (2) ◽  
pp. 22-26
Author(s):  
M. A. Repina ◽  
N. V. Kulagina ◽  
Ya. A. Kornilova

In modern obstetrics there is an urgent problem of treatment of threat of premature labor being one of the basic reasons for perinatal losses. In the article the prospects of Gynipral application in pregnant women, and also the results of practical application of a drug in clinic are considered. It is proved, that the application of beta-adrenomimetic Gynipral allows effectively and without development of complications on the part of the mother to carry out the treatment of premature labor threat, hypoxia a fetus, discoordination in labor, that provides the perinatal morbidity and mortality reduction.

2021 ◽  
Vol 10 (16) ◽  
pp. 3631
Author(s):  
Yolanda Cuñarro-López ◽  
Santiago García-Tizón Larroca ◽  
Pilar Pintado-Recarte ◽  
Concepción Hernández-Martín ◽  
Pilar Prats-Rodríguez ◽  
...  

Coronavirus disease-19 (COVID-19) is perhaps the most worrisome pandemic in the 21st century, having entailed devastating consequences for the whole society during the last year. Different studies have displayed an existing association between pregnancy and COVID-19 severity due to the various physiological changes that occur during gestation. Recent data identified maternal country of origin as an important determinant of COVID-19 presentation in pregnant women. However, the explanation of this fact remains to be fully elucidated. Therefore, the purpose of this work is to analyze the possible relationship between Human Development Index (HDI) of maternal country of origin with the morbimortality of pregnant women and their newborns. Here, we conducted a multicentric, ambispective, observational case-control study (1:1 ratio) and compare with the HDI of each country (group 1—very high HDI, group 2—high HDI, group 3—medium HDI, and group 4—low HDI). In total, 1347 pregnant women with confirmed SARV-CoV-2 infection (cases) were enrolled, and each was paired with one control to give a total number of 2694 participants from 81 tertiary care centers. Among the women with SARS-CoV-2 infection, more cases were produced of perinatal mortality, overall maternal morbidity, COVID-19 maternal morbidity, C-sections, hypertensive maternal morbidity, and perinatal morbidity. Our results described an inverse association between HDI and maternofetal morbidity and mortality. Moreover, the countries with an HDI lower than 1 showed higher rates of patients with maternal COVID-19-related morbidity (6.0% vs. 2.4%, p < 0.001), a need for oxygen therapy (4.7% vs. 1.8%, p < 0.001), and maternal ICU admission (2.6% vs. 1.0%, p = 0.007). Compared to other risk factors such as overweight, obesity, preexisting and obstetric comorbidities, HDI emerged as an independent risk factor explaining much of the increased maternal–perinatal morbidity and mortality detected in our group of cases. Further research is needed to establish to confirm the real impact of this factor and its components on pregnancy outcomes.


2017 ◽  
Vol 53 (4) ◽  
pp. 242
Author(s):  
Nur Oktavia ◽  
Yulistiani Yulistiani ◽  
Unedo H Markus ◽  
Hendriette Irene Mamo

Premature labor is a cause of high rates of perinatal morbidity and mortality. The use of tocolytics is one of the efforts to handle the risk of preterm labor. Tocolytics which are widely used in Indonesia is isoxsuprine and nifedipine. The purpose of this study was to identify the difference of effectiveness and safety of isoxsuprine as tocolytics in the risk of preterm labor. This was an observational study in the form of a case study that was done in detail and depth to the patients who were diagnosed as imminent preterm labor. In conclusion, there were differences in the effectiveness and safety of isoxsuprine and nifedipine as tocolytics in the risk of preterm labor.


1986 ◽  
Vol 67 (1) ◽  
pp. 71-72
Author(s):  
Z. Sh. Gilyazutdinova

The plenary session was devoted to the topical issue of reducing maternal and perinatal morbidity and mortality in late toxicosis of pregnant women. Attention was drawn to the risk factors in the development of this pathology and, first of all, to extragenital diseases of the mother: kidney disease (G. M. Savelyeva, V. N. Serov), chronic tonsillitis, high infectious index in childhood, tonsillectomy during menarche.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Sammya Bezerra Maia e Holanda Moura ◽  
Laudelino Marques Lopes ◽  
Padma Murthi ◽  
Fabricio da Silva Costa

Preeclampsia (PE) affects around 2–5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle, nutritional supplementation, and drugs have been studied. The aim of this paper is to review recent evidence about primary and secondary prevention of preeclampsia.


2020 ◽  
Vol 25 (3) ◽  
pp. 42-47
Author(s):  
Mihaela Corina Radu ◽  
Anca Irina Dumitrescu ◽  
Adrian Calin Boeru ◽  
Loredana Sabina Cornelia Manolescu ◽  
Oana Roxana Dumitrescu ◽  
...  

AbstractIn the last two decades, group B streptococcus (GBS) infection has established itself as a major cause of perinatal morbidity and mortality. The purpose of this study is to identify if the electively induced labor with oxytocin in women with positive cultures of Streptococcus agalactiae, namely the group B streptococcus (GBS), helps the mother and fetus and decreases the risk associated with perinatal transmission of GBS compared with the spontaneous labor. Results associated with induction of labor with oxytocin compared with spontaneous labor in pregnant women who have GBS - positive cervical cultures, are also used to determine whether induction of labor decreases the risk of complications from GBS infection.


2021 ◽  
pp. 50-52
Author(s):  
Ranjana Dhar

BACKGROUND: - Pre-eclampsia is a serious complication of pregnancy and contributes signicantly maternal as well as perinatal morbidity and mortality. So an attempt was made to study the platelet count and bleeding time in cases of preeclampsia. AIM:-(1) To nd out the platelet count and bleeding time in pre-eclamptic woman. rd (2) To compare the values of platelet count and bleeding time in pre-eclamptics and normal pregnant woman in 3 trimester of pregnancy. METHODOLOGY:- 120 pregnant women in age group 18-42 years were included in the study of which 40 women were mild pre-eclamptic, 40 severe pre-eclamptic and 40 normal pregnant women in third trimester of pregnancy. RESULT:- Signicant decrease in platelet count and signicant increase in bleeding time was found between pre-eclamptic in comparison with the normal pregnant women. DISCUSSION:- Platelet count was found to decrease & Bleeding Time increase in pre-eclampsia CONCLUSION:- From this study,it was concluded that platelet count decrease and bleeding time incease with increase in severity of preeclampsia


2021 ◽  
pp. 56-59
Author(s):  
Sumanlata Mendiratta ◽  
Suman Dath.S ◽  
Jasmine Chawla Sharma

Introduction: Preeclampsia is a common cause for increased maternal and perinatal morbidity and mortality in the developing world. Altered lipid prole is associated with preeclampsia. This study was conducted to evaluate maternal and fetal outcome in correlation with altered lipid prole. Material and Methods: A case control study was carried out during June 2016 to full May 2017 in obstetrics and gynecology department, HRH, NDMC Medical college, Delhi. Total 240 pregnant women were included in this study in which 120 normotensive pregnant women taken as control group and 120 preeclamptic women were taken as study group. Statistical analysis was done by SPSS version 21.0. Results: In our study we observed that there was increased systolic and diastolic blood pressure in relation to abnormal lipid prole. There was an increase in maternal morbidities in relation to abnormal lipid prole. Birth weight is signicantly related to severity of lipid parameters. Conclusions: Measurement of serum lipid prole should be done in pregnant women with risk of preeclampsia and other hypertensive disorders to prevent maternal, perinatal morbidity and mortality.


Author(s):  
Aruna Naik ◽  
Susheela Khoiwal ◽  
Nisha Sharma ◽  
Priya Aarthy

Background: Hypertension is one of the common complications in pregnancy and contributes significantly to maternal and perinatal morbidity and mortality. The aim of the present study was to study placental grading by grading by ultrasonography in pregnancy complicated with hypertension and normotensive gravidas. To compare the foetal outcome regarding placental grading and its correlation pattern of placental grade distribution, type of delivery, foetal distress, birth asphyxia, foetal maturity, perinatal morbidity and mortality.Methods: The present study was conducted for a period of 12 months, which included 200 patients who attended OPD at PDRMC, Udaipur. Inclusion criteria was hypertensive pregnant women with BP >140/90 mmHg. Exclusion criteria was Pregnancy associated with other medical disorders, twin gestation, renal and cardiovascular disease and diabetes mellitus.Results: 100 pregnant women with preeclampsia as study group. The most common age group in study group is 22-23 Years. The grade III placenta was found early third trimester in study group. Caesarean delivery was more common mode of delivery in grade III placenta. In foetal outcome small for gestational age was more among the grade III placenta. Foetal distress, birth asphyxia, perinatal mortality, morbidity more among the grade III placenta among the study group.Conclusions: Foetal complications were significantly more in study group compared to control group. Ultrasound placental grade III was statistically significant in correlating with foetal complications like foetal distress, birth asphyxia, perinatal morbidity and mortality. 


2021 ◽  
Vol 1 ◽  
pp. 61-65
Author(s):  
Yu.P.  Vdovichenko ◽  
V.O.  Golyanovskyi

Intrauterine growth restriction is the cause of significant increases in perinatal mortality, morbidity and problems in the development of newborns and infants. The leading place of this pathology is not accidental, because according to various authors, the frequency of perinatal loss associated with it is from 19 to 287‰ and more, the level of perinatal morbidity - from 58.7 to 88.0%.The objective: To determine certain serum and ultrasound markers during the first trimester of pregnancy and to improve the perinatal morbidity and mortality rate in women with intrauterine growth restriction. Materials and methods. A prospective study of pregnant women in the gestation period of 11 weeks 0 days – 13 weeks 6 days, which was to determine the level of plasma protein A associated with pregnancy (PAPP-A), mean platelet volume (MPV), and ultrasound placenta examination. Pregnant women were divided into 2 groups: the main group (n1-52) and the control group (n2-50). The study group consisted of women with a low PAPP-A level and changes in the mean platelet volume towards their increase. It is this group of women that is more sensitive, in our opinion, for the development of placental disorders and the occurrence of fetal growth retardation.Results. In this study, PAPP-А levels in 39 pregnant women were <0.5 MoM, and WTO levels in 36 cases were> 10 fl, which, according to the literature, can be used as markers of early prediction of ZRP.Ultrasound type of disorders of the first stage of trophoblast invasion is described as intra- and / or periplacental pathological areas, which can be considered the causes of placental insufficiency, which results in a risk of ZRP. According to the study, high specificity and sensitivity of Doppler parameters with the determination of indices (PI and IR) in the uterine arteries were established. Conclusions. The results of the study showed that performing a screening based on a detailed history and determining PAPP-A, MPV, and ultrasound examination at first trimester of pregnancy in women with the risk of IUGR allows for prophylactic treatment and monitoring of pregnancy and thus reduces neonatal morbidity and mortality.


2014 ◽  
Vol 68 (2) ◽  
pp. 104-106
Author(s):  
Aleksandra Pivkova Veljanovska ◽  
Sonja Genadieva Stavrik ◽  
Zlate Stojanoski ◽  
Lazar Cadievski ◽  
Adela Stefanija ◽  
...  

Abstract The article presents a case with diagnosed Hodgkin disease (HD) during pregnancy. The aim of this case study was to present diagnostic possibilities in determining HD stage during pregnancy and therapeutic dilemmas. The incidence of HD during pregnancy is 3.2% of all cases with this malignant hematological disorder. The treatment of this disease during pregnancy depends on disease-related factors, pregnancy-related factors, as well as possible implications for fetal morbidity and mortality. The need of analysis of the nature of the disease during pregnancy indicates examination of a larger series of pregnant women with HD and the drawn conclusions affect the decision whether chemotherapy treatment should start immediately or it should be postponed for after delivery.


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