scholarly journals Quantity of Antibiotic Use and Resistance Pattern of Gut Normal Flora Escherichia coli at Intensive Care Unit and Tropic Infection Ward, Dr Soetomo Hospital, Surabaya, Indonesia

2021 ◽  
Vol 56 (3) ◽  
pp. 159
Author(s):  
Mohammad Akbaruddin Sholeh ◽  
Kuntaman Kuntaman ◽  
Usman Hadi

Resistance to antibiotics is increasing worldwide, including in Indonesia. The use of antibiotics is the most common cause of microorganism resistance. Individuals who received antibiotic therapy impacton changes of normal micro-flora resistance through selective pressure. This study aims to analyze the relationship of the quantity of antibiotic use with the pattern of resistance of gut normal flora Escherichia coliamong patients in Intensive Care Unit (ICU) and Tropic Infection Ward, Dr. Soetomo Hospital, Surabaya. This study was cross-sectional design with 64 samples (32 the ICU and 32 in Tropic Infection Ward). The total sample were collected for three Months. Identification of intestinal microflora was done with McConkey differential selective medium, followed by IMViC biochemical test, and sensitivity test by antibiotic disc diffusion method. Data were analyzed with Chi square test and Fisher'sExact test. There was no significant difference (p=0.441) in the quantity of antibiotic use between ICU and Tropic Infection Ward. There was no significant difference (p>0.05) in normal intestinal flora Escherichia coli resistance pattern between Tropic Infection Ward and ICU against12 types of antibiotics. Ceftriaxone was the most widely used antibiotic in the Tropic Infection Ward of 54 DDD and ICU of 100 DDD. The highest percentage of intestinal flora Escherichia coli  resistance at the ICU was ceftriaxone as manyas 18 (56.3%) and at Tropic Infection Ward on ciprofloxacin and levofloxacin 20 (62.5%). The other study in Primary Health center, showed that theresistance rates of both wards were significantly different as compared to intestinal flora of patients in primary health center (p <0.001), in whichthe use of antibiotics in primary health center was also lower (1.6 DDD). There was no significant difference (p>0.05) The pattern of bacterial resistance between patient with and without antibiotic use at Tropic Infection Ward and ICU Conclusion: the quantity of antibiotic use was not significantly different against resistnt gut flora between patients in ICU and Tropic Infection ward. The pattern of bacterial resistance between patient with and without antibiotic use was also not significantly different.

2020 ◽  
Vol 56 (3) ◽  
pp. 159
Author(s):  
Mohammad Akbaruddin Sholeh ◽  
K Kuntaman ◽  
Usman Hadi

This study aimed to analyze the relationship of the quantity of antibiotic use with the pattern of resistance of gut normal flora Escherichia coli among patients in Intensive Care Unit (ICU) and Tropic Infection Ward, Dr. Soetomo Hospital, Surabaya. This study was cross-sectional design with 64 samples (32 the ICU and 32 in Tropic Infection Ward). The total sample were collected for three Months. Identification of intestinal microflora was done with McConkey differential selective medium, followed by IMViC biochemical test, and sensitivity test by antibiotic disc diffusion method. Data were analyzed with Chi square test and Fisher's Exact test. There was no significant difference (p=0.441) in the quantity of antibiotic use between ICU and Tropic Infection Ward. There was no significant difference (p>0.05) in normal intestinal flora Escherichia coli resistance pattern between Tropic Infection Ward and ICU against 12 types of antibiotics. The highest percentage of intestinal flora Escherichia coli  resistance at the ICU was ceftriaxone as many as 18 (56.3%) and at Tropic Infection Ward on ciprofloxacin and levofloxacin 20 (62.5%). The other study in Primary Health center, showed that the resistance rates of both wards were significantly different as compared to intestinal flora of patients in primary health center (p <0.001), in which the use of antibiotics in primary health center was also lower (1.6 DDD). There was no significant difference (p>0.05) The pattern of bacterial resistance between patient with and without antibiotic use at Tropic Infection Ward and ICU. The quantity of antibiotic use was not significantly different against resistnt gut flora between patients in ICU and Tropic Infection ward. The pattern of bacterial resistance between patient with and without antibiotic use was also not significantly different.


2016 ◽  
Vol 7 (3) ◽  
pp. 93-98 ◽  
Author(s):  
Fernanda Borges Carlucio da Silva ◽  
Rosangela Filipini ◽  
Ana Paula Guarnieri ◽  
Nathalia Grangeiro Vieira ◽  
Andrea Bonvini ◽  
...  

2018 ◽  
Vol 5 (2) ◽  
pp. 27-31
Author(s):  
Maryam Ulfah ◽  
Yani Kamasturyani ◽  
Putri Mutiara Ramandani

Background:Knowledge of leprosy prevention is the knowledge of a person doing a first line prevention or pervention action before a disease occurs. Based on data from Cirebon district Health OfficeThe incident of leprosy are 232 patients.According to the data primary health center Losari, Kedaton and Babakan There are 37 leprosy patients. Purpose: This research aimed to know an overview of knowledge about the prevention of leprosy, know an overview risk of cutaneous transmission, and knowlegde connection of prevention with leprosy transmission of primary health center Lossari, Kedaton and Babakan Cirebon District. Method:This is quantitative with Cross Sectional Study design. The population in this research is family members of leprosy primary health center Losari, Kedaton dan Babakan Cirebon district. The samples were choosen by Propotional Random Sampling which amounted to 114 respondents. The data retrieval research was conducted on 15 July – 15 September 2018. The research instrument was a questionnaire. Data analysis using Chi Square test. Result:The result of univariate analysis shows that connection of prevention leprosy was motsly good, that is mostly less 14 respondent (46,7%) and leprosy transmission mostly not risk 21 respondent (70,0%),. The result of chi square test was obtained p value = 0,011. Conclusion:Its indicatedthat there is a relationship betweenIndicating that H0 is rejected an Ha accepted means the a knowlegde connection of prevention with leprosy transmission of primary health center Lossari, Kedaton and Babakan Cirebon District


Author(s):  
Deviani Saskia Putri ◽  
Ayun Sriatmi ◽  
Eka Yunila Fatmasari

Background: Treatment adherence among patients with severe mental disorders is needed to avoid drop-outs, relapses, and shackling. Kedungmundu Primary Health Center in Semarang City is known to have a low treatment adherence to patients with severe mental disorders. This study aimed to determine the factors associated with treatment adherence among patients with severe mental disorders.Methods: A quantitative study with a cross-sectional approach. The samples were 73 patients with severe mental disorders at The Kedungmundu Primary Health Center. Data were collected using questionnaires and analyzed using frequency distribution analysis and Spearman Rank Correlation Test.Results: The results indicated that knowledge (p = 0,000; r = 0,715), attitudes (p = 0,000; r = 0,839), family support (p = 0,000; r = 0,427), assessment of health workers (p = 0,000; r = 0,456), and the need for health services (p = 0,000; r = 0,716) have a positive correlation with treatment adherence among severe mental disorders patients.Conclusion: Kedungmundu Primary Health Center is suggested to provide psychoeducation to patients and families, improve the implementation of mental health programs, and empower mental health cadres.


2019 ◽  
Vol 5 (1) ◽  
pp. 56
Author(s):  
Ramanathan Thenambigai ◽  
HuluvadiShivalingaiah Anwith ◽  
SreeramaReddy Kaushik ◽  
M Madhusudan ◽  
DandiganahalliShivaram Priyanka ◽  
...  

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