Burning mouth syndrome caused by xerostomia secondary to amlodipine

Background: Xerostomia, generally referred to as dry mouth, has been identified as a side effect of more than 1,800 drugs from more than 80 groups. This condition is frequently unrecognised and untreated but may affect patients’ quality of life and cause problems with oral and medical health, including burning mouth syndrome (BMS). Purpose: The purpose of this case is to discuss how to manage a patient with BMS caused by xerostomia secondary to medication that has been taken by the patient. Case: We reported that a 45-year-old male military officer from the Royal Malaysian Air Force came to Kuching Armed Forces Dental Clinic with dry mouth and a burning sensation since he started taking 10 mg of amlodipine due to his hypertension. After a thorough physical and history examination, we made a diagnosis of burning mouth syndrome (BMS) caused by xerostomia secondary to amlodipine. Case Management: Oral hygiene instructions, diet advice and prescription of Oral7 mouthwash has been given to reduce the symptoms of BMS. The patient has been referred to the general practitioner to reduce his amlodipine dosage from 10 mg to 5 mg (OD) in order to prevent xerostomia, and oral hygiene instructions have been given. A review after two weeks showed significant changes in the oral cavity, and the patient was satisfied as he is no longer feeling the burning sensation and can enjoy his food without feeling difficulty in chewing and swallowing. Conclusion: Adverse drug events are normal in the oral cavity and may have a number of clinical presentations such as xerostomia. Xerostomia can cause many implications as saliva helps in maintaining oral mucosa and has a protective function. The signs of adverse drug incidents in the oral cavity should be identified to oral health care professionals.

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Burning Mouth Syndrome pada wanita Menopause dengan Hiposalivasi, Coated Tongue dan Gangguan Pengecapan serta Penatalaksanaannya

Majalah Kedokteran Gigi Indonesia ◽

10.22146/majkedgiind.15920 ◽

2012 ◽

Vol 19 (1) ◽

pp. 82

Author(s):

Sri Hadiati

Keyword(s):

Oral Cavity ◽

Postmenopausal Women ◽

Vitamin B1 ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Chewing Gum ◽

Affected Patient ◽

Burning Mouth ◽

Oral Burning

Blackground: Burning mouth syndrome (BMS) is a disorder that is characterized by a burning sensation of the oral cavity in the absence of visible local or systemic abnormalities. Affected patient often present with multiple oral complaints, including burning, dryness and taste alterations. The exact cause of burning mouth syndrome often is difficult to pin point. Conditions that have been reported in association with burning mouth syndrome include menopause, hyposlivation, coated tongue, taste alterations and psychologic condition. Objective: To report a case of burning mouth syndrome in postmenopausal women with hyposalivation, coated tongue, taste alterations and psychologic condition and its management. Case and management: a case of burning mouth syndrome in women with menopause, hyposalivation, coated tongue, and taste alterations, was managed effectively by gabapentin 100mg, probiotic chewing gum, diazepam 2mg and vitamin B1, B6, B12. Conclusion: Oral burning appears to be most prevalent in postmenopausal women often present with multiple oral complaints, including burning, dryness and taste alterations, in this case was managed effectively by gabapentin 100mg, prebiotic chewing gum, diazepam 2mg and vitamin B1, B6, B12.

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Suicidal Behavior in a Patient with Burning Mouth Syndrome

Case Reports in Psychiatry ◽

10.1155/2014/405106 ◽

2014 ◽

Vol 2014 ◽

pp. 1-3

Author(s):

Konstantinos Kontoangelos ◽

Evmorfia Koukia ◽

Vasilis Papanikolaou ◽

Aris Chrysovergis ◽

Antonis Maillis ◽

...

Keyword(s):

Chronic Pain ◽

Oral Cavity ◽

Psychiatric Comorbidity ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Multiple Forms ◽

Case Presentation ◽

Local Pain ◽

Burning Mouth

Introduction. Chronic pain of the oral cavity is a long-term condition and like all other types of chronic pain is associated with numerous comorbidities such as depression or anxiety.Case Presentation. This is a case of a 93-year-old patient suffering from chronic oral cavity pain who repeatedly stabbed his palate due to ongoing local pain, over the last few months, which he could not further tolerate. The patient was suffering from depression and also a diagnosis of “burning mouth syndrome” (BMS) was made.Discussion. Burning mouth syndrome (BMS) is characterized by a burning sensation in the tongue or other oral sites. BMS has high psychiatric comorbidity but can occur in the absence of psychiatric diagnosis. Patients with multiple forms of pain must be considered as potential candidates for underdiagnosed depression (major) and suicidal thoughts.

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Burning mouth syndrome- An Oral Physicians Dilemma

International Journal Of Applied Research and Studies ◽

10.20908/ijars.v6i4.7614 ◽

2017 ◽

Vol 6 (4) ◽

Author(s):

N. Kavitaa

Keyword(s):

Oral Mucosa ◽

Facial Pain ◽

Clinical Signs ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Pain Disorder ◽

Treatment Modalities ◽

Clear Cut ◽

Burning Mouth

Burning Mouth Syndrome (BMS) is a chronic oro-facial pain disorder that affects both genders, but predominately with higher female predilection. The condition is characterized by burning sensation present over the oral mucosa and tongue, with no definable clinical signs. The etiology for BMS is not clear cut, so does the quality of treating the condition is hampered. The present paper reviews the etiology, pathophysiology, diagnostic criteria’s and treatment modalities in treating BMS which poses as a great challenge for the oral physicians.

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Burning Mouth Syndrome: Case Reports

Revista Portuguesa de Psiquiatria e Saúde Mental ◽

10.51338/rppsm.2019.v5.i4.22 ◽

2020 ◽

Vol 5 (4) ◽

pp. 76-78

Author(s):

Catarina da Costa Campos ◽

Maria do Céu Ferreira ◽

Joana Mesquita

Keyword(s):

Psychological Factors ◽

Case Reports ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Therapeutic Approaches ◽

Physiological Factors ◽

Common Chronic Disease ◽

Clinically Normal ◽

Nosological Entity ◽

Burning Mouth

Burning mouth syndrome (BMS) is a relatively common chronic disease of unclear etiopathogenesis. It is defined as a distinctive nosological entity that includes all forms of burning sensation in the mouth, including stinging sensation or pain, in association with an oral mucosa that appears clinically normal, in the absence of local or systemic diseases. It was hypothesized that psychological factors could influence its appearance, but also physiological factors, with some authors suggesting a neuropathic etiology. Regarding the treatment of BMS, benefits were found in individual or group psychotherapy, as well as in psychopharmacological interventions, however its current therapeutic approach is not completely satisfactory. In this paper we describe two cases of BMS and discuss the possible etiopathogenesis and current therapeutic approaches.

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A Case of Vestibular Schwannoma with Oral Burning Sensation: Surgical Complication or Burning Mouth Syndrome?

10.21203/rs.3.rs-34585/v1 ◽

2020 ◽

Author(s):

Takayuki Suga ◽

Miho Takenoshita ◽

Trang T.H Tu ◽

Chaoli Hong ◽

Chihiro Takao ◽

...

Keyword(s):

Vestibular Schwannoma ◽

Facial Pain ◽

Somatic Symptom ◽

Bitter Taste ◽

Surgical Complication ◽

Exceptional Case ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Burning Mouth ◽

Oral Burning

Abstract Background: Vestibular schwannoma (VS) or acoustic neuroma is a benign brain tumor. Despite improvements in surgical technique, the removal of VS is related to some complications of which the recovery is difficult and sometimes lead to permanent deficits. About 10.7% of complication of vestibular schwannoma surgery is reported to affect facial or tongue area, including numbness of pain, which is similar to a typical symptom of burning mouth syndrome (BMS). However, up to our knowledge, there is no documented case of BMS either comorbid with vestibular schwannoma or occur due to surgery complications. Clinical Presentation: A 46-year-old woman complained about left-sided facial pain, a burning sensation on the left side of her tongue and maxilla, and a spontaneous bitter taste. Four years before her first visit to our clinic, left-sided facial pain and burning sensation on the left side of the tongue suddenly became severe. She visited a neurosurgeon and VS was found in the left cerebellopontine angle. After the tumor was removed, facial pain, burning sensation of the tongue, and bitter taste improved simultaneously but quickly recurred after a while. The patient had a panic attack because of severe pain and started visiting a psychiatrist. The psychiatrist diagnosed her as having somatic symptom disorder and depression, prescribing sertraline 100 mg, zolpidem 5 mg, and lorazepam 1.0 mg and referred her to our clinic. At the first visit, no abnormal intraoral nor extraoral findings were detected. Based on the characteristics of the pain, we made a diagnose of BMS. Amitriptyline was initiated at 10 mg/day and increased to 30 m. Within 1.5 months, the pain and burning sensation of the tongue and maxilla almost remitted completely, whereas bitter taste showed moderate improvement. Conclusions: Our case suggests there might be an exceptional case in which BMS and VS can occur simultaneously. Specifically, an oral burning sensation and dysgeusia after VS surgery are not always a case of surgical complication or untreatable.

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Pitfalls for diagnosis of burning mouth-like syndrome

Romanian Journal of Stomatology ◽

10.37897/rjs.2021.3.3 ◽

2021 ◽

Vol 67 (3) ◽

pp. 150-155

Author(s):

Raluca Ema Pîrvu ◽

◽

Ioanina Părlătescu ◽

Șerban Țovaru ◽

Cosmin Dugan ◽

...

Keyword(s):

Oral Cavity ◽

Medical Practice ◽

Burning Mouth Syndrome ◽

Diagnostic Approach ◽

Anxiety And Depression ◽

Endocrine Disorders ◽

Systemic Diseases ◽

Burning Mouth ◽

Scientific Framework

This research gives a scientific framework for burning mouth syndrome(BMS) etiology and diagnostic approach in clinical dental and medical practice. BMS-like symptoms can be induced by systemic diseases such as diabetes, gastrointestinal, endocrine disorders, allergy etc. or by local oral cavity conditions as candidiasis or geographic tongue or odontogenic causes. Because the etiology of BMS is multifactorial, treatment can only be distinctive, and is aimed at relieving symptoms. The complexity of BMS symptoms and associated psychosocial infirmities, anxiety and depression raise the need for a multidisciplinary and individualised approach.

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MANAGEMENT OF BURNING MOUTH SYNDROME: A LITERATURE REVIEW

ODONTO Dental Journal ◽

10.30659/odj.6.1.43-50 ◽

2019 ◽

Vol 6 (1) ◽

pp. 43

Author(s):

I Nyoman Gede Juwita Putra ◽

Riani Setiadhi

Keyword(s):

Literature Review ◽

Hormone Replacement ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Oral Lesions ◽

Pharmacologic Treatment ◽

Laboratory Findings ◽

Physiological Basis ◽

Topical Medication ◽

Burning Mouth

Background: Burning mouth syndrome (BMS) is a chronic idiopathic oral dysaesthesia that presents as a burning sensation in the oral cavity usually without any specific oral lesions or laboratory findings. Burning sensations may appear on the buccal mucosa, hard and soft palate, tongue and lips. BMS appears to be more prevalent in postmenopausal women. The term menopause is often used for a condition in which the permanent cessation of the primary function of the ovaries in humans that occurs especially in middle-aged women. Available evidence suggested that BMS is a multifactorial disorder with physiological basis. Pathophysiology of BMS remains unclear. The etiopathogenesis in most patients who complain of burning sensations have interactions with several factors such as local, systemic, and/ or psychogenic factors. The aim of this literature review was to assess and evaluate the management of BMS comprehensively.Discussion: The therapy of BMS including hormone replacement therapy,systemically therapy, such as antidepressants, clonazepam and topical medication (clonidine and capsaicin) and reassurance as the stress management.Conclusion: Proper management of the BMS involves the combination of pharmacologic treatment and psychotherapy, as well as reassurance is an important thing

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Burning Mouth Syndrome: An Enigmatic Disorder

Kathmandu University Medical Journal ◽

10.3126/kumj.v11i2.12498 ◽

2015 ◽

Vol 11 (2) ◽

pp. 175-178 ◽

Cited By ~ 2

Author(s):

MA Javali

Keyword(s):

Medical Journal ◽

Clinical Practice ◽

Current Knowledge ◽

Clinical Signs ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Aged Patients ◽

Oral Pain ◽

Mucosal Lesions ◽

Burning Mouth

Burning mouth syndrome (BMS) is a chronic oral pain or burning sensation affecting the oral mucosa, often unaccompanied by mucosal lesions or other evident clinical signs. It is observed principally in middle-aged patients and postmenopausal women and may be accompanied by xerostomia and altered taste. Burning mouth syndrome is characterized by an intense burning or stinging sensation, preferably on the tongue or in other areas of mouth. This disorder is one of the most common, encountered in the clinical practice. This condition is probably of multifactorial origin; however the exact underlying etiology remains uncertain. This article discusses several aspects of BMS, updates current knowledge about the etiopathogenesis and describes the clinical features as well as the diagnosis and management of BMS patients. DOI: http://dx.doi.org/10.3126/kumj.v11i2.12498 Kathmandu University Medical Journal Vol.11(2) 2013: 175-178

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Effect of Oral Care Gel for Burning Mouth Syndrome in a Patient with Hepatitis C: A Case Report

Case Reports in Gastroenterology ◽

10.1159/000479495 ◽

2017 ◽

Vol 11 (2) ◽

pp. 480-487 ◽

Cited By ~ 1

Author(s):

Yumiko Nagao ◽

Yuji Kawahigashi ◽

Kanae Kimura ◽

Michio Sata

Keyword(s):

Hepatitis C ◽

Oral Care ◽

Depressive Mood ◽

Virologic Response ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Therapeutic Effects ◽

Number Of Patients ◽

Long Term Follow Up ◽

Burning Mouth

Burning mouth syndrome (BMS) is a burning sensation in the mouth with no underlying dental or medical cause. To date, there is no satisfactory treatment for BMS. Herein, we present the case of a 42-year-old female presenting with hepatitis C virus infection along with BMS. Despite two interferon therapies and a sustained virologic response, the discomfort in her oral mucosa persisted. At the age of 51, the patient complained of burning sensation and tingling pain in the tongue; a thin layer of REFRECARE-H®, an oral care gel (therapeutic dentifrice), was applied on the oral membrane after each meal for 60 days. Application of REFRECARE-H® decreased the various symptoms including tingling pain, oral discomfort, breath odor, sleep disorder, depressive mood, and jitteriness. The improvement in quality of life continued for 30 days after application of the gel. These findings indicate that REFRECARE-H® may be effective in reducing the symptoms associated with BMS. Long-term follow-up studies with larger number of patients are required to elucidate the therapeutic effects of this gel.

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Burning mouth syndrome – a burning enigma

Medicina Fluminensis ◽

10.21860/medflum2021_365333 ◽

2021 ◽

Vol 57 (1) ◽

pp. 4-16

Author(s):

Ana Andabak Rogulj ◽

Ivana Škrinjar ◽

Danica Vidović Juras ◽

Vanja Vučićević Boras † ◽

Božana Lončar Brzak

Keyword(s):

Current Knowledge ◽

Salivary Flow ◽

Burning Mouth Syndrome ◽

Burning Sensation ◽

Unknown Etiology ◽

Laboratory Findings ◽

Chronic Pain Condition ◽

Appropriate Treatment ◽

Oral Mucosal Lesions ◽

Burning Mouth

Burning Mouth Syndrome (BMS) is a chronic pain condition characterized by an intraoral burning sensation and an absence of oral mucosal lesions and disturbances in laboratory findings. Burning symptoms usually affect the anterior two-thirds of the tongue, its lateral borders, hard palate and labial mucosa, but other oral cavity sites may also be affected. Taste alterations and a decrease in the salivary flow rate frequently accompany the burning symptoms. This condition mostly affects peri- and postmenopausal women. To date, the etiology of BMS remains unclear. This unknown etiology means that no appropriate treatment is currently available. A large number of the treatments and medications have been tried for BMS, but treatment management remains unsatisfactory in some patients. The purpose of this article is to present current knowledge on the treatment of BMS.

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