REDESIGNING THE ROLES OF TUBERCULOSIS TREATMENT SUPPORTER IN INDONESIA

Background: Indonesia is the third-highest rank country for tuberculosis. Many studies already compared the effectiveness of the Directly Observed Treatment-Short (DOTS) course with self-administered therapy (SAT) in tuberculosis treatment and pointed out that DOTS did not improve the succession rate (SR) significantly. The participation of a tuberculosis treatment supporter that has an important rule in the DOTS strategy to improve the patients’ adherence in taking treatment should be reviewed.Aims: The study aims to analyze the determination of environmental factors in the effectiveness of tuberculosis treatment which can lead to the program improvement issue.Method: This research was a cross-sectional study conducted by involving 55 of 121 tuberculosis patients. The sampling frame was tuberculosis patients who were reported under the first and third quarters in Primary Healthcare Center of Tanah Kalikedinding as it had failed to reach the succession rate during 2012-2015.Results: These findings indicated that the social environment of tuberculosis patients significantly contributed to their adherence to taking medicine. It showed that tuberculosis treatment supporters had an essential role in maintaining the patients’ adherence. Tuberculosis treatment supporters who lived in one roof with the patient tended to get 2.265 times risk to be contagious. This study also pointed out that the physical environment had the highest determination in the success rate of treatment.Conclusion: Modifying the physical environment of tuberculosis patients can be the greater alternative program to fight tuberculosis rather than the tuberculosis treatment supporters. Tuberculosis treatment supporters must be provided with universal protection due to their high-risk position to be contagious.Keywords: treatment adherence, DOTS, patient environment, treatment effectiveness.

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Nonadherence to tuberculosis treatment and associated factors among patients using directly observed treatment short-course in north-west Nigeria: A cross-sectional study

SAGE Open Medicine ◽

10.1177/2050312121989497 ◽

2021 ◽

Vol 9 ◽

pp. 205031212198949

Author(s):

Cylia Nkechi Iweama ◽

Olaoluwa Samson Agbaje ◽

Prince Christian Ifeanachor Umoke ◽

Chima Charles Igbokwe ◽

Eyuche Lawretta Ozoemena ◽

...

Keyword(s):

Confidence Interval ◽

Odds Ratio ◽

Adjusted Odds Ratio ◽

Cross Sectional Study ◽

Medication Nonadherence ◽

Cross Sectional ◽

Tuberculosis Patients ◽

North West ◽

Short Course ◽

Directly Observed Treatment

Introduction: Tuberculosis is a public health problem in Nigeria. One of the most effective ways of controlling tuberculosis is the directly observed treatment short-course. However, some factors influence tuberculosis patients’ treatment nonadherence via directly observed treatment short-course. The study objective was to assess medication nonadherence and associated factors among tuberculosis patients in north-west Nigeria. Methods: A cross-sectional study enrolled tuberculosis patients using directly observed treatment short-course in public health facilities in Kano and Kaduna States from January 2015 to June 2016. The sample selection was conducted via a multistage sampling procedure. Data were collected using tuberculosis patients’ demographic and clinical characteristics forms, well-validated structured instruments, and medical records. SPSS version 20 was used for data analysis. Logistic and multivariable logistic regression analyses to determine factors of medication nonadherence ( P < 0.05) Results: Complete responses from 390 patients out of the 460 patients recruited for the study were used for data analyses. The mean age was 51.5 (standard deviation = ±13.8) years. The mean tuberculosis medication adherence questionnaire score was 4.35 ± 1.12. The prevalence of nonadherence to tuberculosis medication was 30.5%. Multivariable logistic regression analysis showed that having a monthly income between #100,000 and #199, 000 (adjusted odds ratio = 0.01; 95% confidence interval: 0.00–0.13), being widowed (adjusted odds ratio = 26.74, 95% confidence interval: 2.92–232.9), being married (adjusted odds ratio = 120.49, 95% confidence interval: 5.38–271.1), having a distance <5 km to directly observed treatment short-course center from home (adjusted odds ratio = 0.06, 95% confidence interval: 0.00–0.01), having a tuberculosis/HIV co-infection (adjusted odds ratio = 0.01, 95% confidence interval: 0.12–0.35), use of antiretroviral treatment and cotrimoxazole prophylaxis therapy medications (adjusted odds ratio = 24.9, 95% confidence interval: 19.6–304.3) were associated with tuberculosis medication nonadherence. Conclusion: Tuberculosis medication nonadherence was high among the patients. Thus, patient-specific adherence education, attenuation of potential factors for tuberculosis medication nonadherence, and continual resource support for tuberculosis patients are needed to improve treatment outcomes.

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Delays to anti-tuberculosis treatment intiation among cases on directly observed treatment short course in districts of southwestern Ethiopia: a cross sectional study

BMC Infectious Diseases ◽

10.1186/s12879-019-4089-x ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 6

Author(s):

Abyot Asres ◽

Degu Jerene ◽

Wakgari Deressa

Keyword(s):

Cross Sectional Study ◽

Tuberculosis Treatment ◽

Sectional Study ◽

Cross Sectional ◽

Southwestern Ethiopia ◽

Short Course ◽

Directly Observed Treatment

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Missed opportunity for standardized diagnosis and treatment among adult Tuberculosis patients in hospitals involved in Public-Private Mix for Directly Observed Treatment Short-Course strategy in Indonesia: a cross-sectional study

BMC Health Services Research ◽

10.1186/1472-6963-10-113 ◽

2010 ◽

Vol 10 (1) ◽

Cited By ~ 10

Author(s):

Ari Probandari ◽

Lars Lindholm ◽

Hans Stenlund ◽

Adi Utarini ◽

Anna-Karin Hurtig

Keyword(s):

Cross Sectional Study ◽

Diagnosis And Treatment ◽

Sectional Study ◽

Cross Sectional ◽

Tuberculosis Patients ◽

Short Course ◽

Directly Observed Treatment ◽

Public Private Mix ◽

Missed Opportunity

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Socio-demographic determinants of tuberculosis patients attending directly observed treatment short course centre in urban Ghaziabad, Uttar Pradesh

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20201976 ◽

2020 ◽

Vol 7 (5) ◽

pp. 1756

Author(s):

Manoj Kumar Yadav ◽

Mohit Raghav ◽

S. S. Chaudhary ◽

Manisha .

Keyword(s):

Nuclear Family ◽

Uttar Pradesh ◽

Cross Sectional Study ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Tuberculosis Patients ◽

Short Course ◽

Directly Observed Treatment ◽

Multistage Sampling

Background: Tuberculosis was the first infectious disease declared by the WHO as a global health emergency. Men are more commonly affected than women. The case notifications were higher in males than in females most countries. The objective of the study was to assess socio-demographic determinants of tuberculosis patients attending directly observed treatment short course (DOTS) centre in Urban Ghaziabad.Methods: This was an observational cross-sectional study. The study was carried out in selected DOTS centres of district Ghaziabad. 850 study subjects age group more than 15 years were included. Multistage sampling was done. Numbers and percentage were used. SPSS version 13 was used for statistical analysis.Results: Majority 41.17% of tuberculosis (TB) patients belonged to 15-25 years age group. 30.58% patients were in 26-35 years age group followed by 23.52% in 36-45 years age group and least 4.70% were in >45 years age group. Majority 54.1% of TB patients were females that compared to 45.9% were males. Among tuberculosis patients majority 58.82% were married as compared to 40% were unmarried and least 1.18% were widow. 75.29% tuberculosis patients were Hindus as compared to 22.35 were Muslims and least 2.35% were Sikh/Christian. Among tuberculosis patients majority 44.71% were from nuclear family. 31.76% had joint family and least 23.53% had 3rd generation family.Conclusions: It was concluded that socio-demographic determinants were low. It was recommended to raise socioeconomic standard of population, give health education to improve personal habit and stop TB transmission.

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An audit of diagnosis and treatment of tuberculosis in Ethiopia

African Journal of Primary Health Care & Family Medicine ◽

10.4102/phcfm.v6i1.582 ◽

2014 ◽

Vol 6 (1) ◽

Author(s):

Valerie J. Ehlers ◽

Getahun S. Aragaw

Keyword(s):

Pulmonary Tuberculosis ◽

Healthcare Providers ◽

Cross Sectional Study ◽

Tuberculosis Treatment ◽

Diagnosis And Treatment ◽

Cross Sectional ◽

Tuberculosis Patients ◽

Resistant Tuberculosis ◽

National Tuberculosis ◽

Smear Negative

Background: Despite the existence of national tuberculosis guidelines (NTG) in Ethiopia, the incidence and prevalence of tuberculosis did not decline markedly. Audits could attempt to determine whether or not healthcare professionals actually implemented these guidelines, as non-implementation could contribute to suboptimal tuberculosis treatment outcomes.Aim: To evaluate healthcare providers’ implementation of Ethiopia’s NTG during the diagnosis and treatment of tuberculosis in order to enhance tuberculosis treatment outcomes.Methods: A descriptive, cross-sectional study design was used.Results: Healthcare providers implemented the NTG during tuberculosis diagnosis for female (60.9%; n = 67) and male (56.1%; n = 69) patients. The correct numbers of anti-tuberculosis pills, complying with the NTG recommendations, were prescribed for 91.8% (n = 101) of the women and for 90.2% (n = 111) of the men. However, both over- and under-prescriptions of anti-tuberculosis drugs occurred. There was an over-diagnosis of smear-negative pulmonary tuberculosis. Only 2.6% (n = 2) of the 76 smear-negative pulmonary tuberculosis patients had been diagnosed correctly.Conclusion: Implementation of the NTG should be enhanced, especially with regard to the diagnosis of smear-negative pulmonary tuberculosis patients and the correct prescription of anti-tuberculosis drugs. This would help to increase the number of correctly-diagnosed and -treated tuberculosis patients, improve tuberculosis treatment outcomes, decrease the spread of tuberculosis and prevent the development of multi-drug-resistant tuberculosis strains.

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