scholarly journals Efficiency of rehabilitation measures in reduction of perinatal morbidity

2009 ◽  
Vol 8 (4) ◽  
pp. 134-139
Author(s):  
T. S. Krivonogova ◽  
T. Ye. Tropova
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Health Promotion ◽  
Pregnant Women ◽  
Stress Hormones ◽  
Rehabilitation Program ◽  
Health Promotion Program ◽  
Perinatal Morbidity ◽  
The Central Nervous System ◽  
Maternal Disease

The clinical examination of 198 pregnant women after the health promotion program and their infants has been carried out. The content of stress hormones and the intensity of processes of lipid peroxidation have been studied, and adaptation abilities have been assessed. The use of the proposed rehabilitation program for pregnant women at early gestational ages favors the reduction of occurrence of feto-maternal disease and the increase of the adaptation reserve of women. Infants, whose mothers received the health promotional program, 3.5 times rarely had signs of the perinatal affection of the central nervous system.

scholarly journals METHOD FOR PREDICTING PERINATAL HYPOXIC LESIONS OF THE CENTRAL NERVOUS SYSTEM IN NEWBORNS

2019 ◽  
Vol 64 (2) ◽  
pp. 89-93 ◽  
Author(s):  
A. . Smirnova ◽  
N. . Borzova ◽  
N. . Sotnikova ◽  
A. . Malyshkina ◽  
E. . Bojko
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Venous Blood ◽  
Perinatal Morbidity ◽  
The Central Nervous System

Perinatal lesions of the Central nervous system (CNS) in newborns occupy a leading place in the structure of perinatal morbidity and subsequent disability of children. To identify the features of the content of sRAGE in pregnant women with threatening preterm labor (UPR) in the period of 22-27 weeks, who subsequently gave birth to children with perinatal CNS lesion. Serum of venous blood of pregnant women with UPR at the term of 22-27 weeks was determined by ELISA once the content of sRAGE. If the value of sRAGE in pregnant women is 659.5 PG/ml or less, perinatal hypoxic lesions of the Central nervous system in newborns are predicted with an accuracy of 75.8% (sensitivity of 82.6%, specificity of 66.7%).

scholarly journals SOME ASPECTS OF THE PATHOGENESIS OF ISCHEMIC-HYPOXIC LESIONS OF THE CENTRAL NERVOUS SYSTEM IN NEWBORNS

2015 ◽  
Vol 4 (2) ◽  
pp. 112-115
Author(s):  
Lyudmila Viktorovna Ledyaikina ◽  
Larisa Alexandrovna Balykova ◽  
Svetlana Vasilyevna Garina ◽  
Olga Nikolaevna Soldatova ◽  
A A Tolkunova ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Lipid Metabolism ◽  
Red Blood Cells ◽  
Brain Damage ◽  
Blood Cells ◽  
Phospholipid Bilayer ◽  
Care Practice ◽  
Perinatal Morbidity ◽  
The Central Nervous System

The problem of perinatal morbidity in case of insufficiently high fertility in Russia is one of the most relevant at the monent. The leading cause of perinatal morbidity and mortality continue to remain hypoxic-ischemic brain damage the fetus and newborn. Ischemic-hypoxic damage of the central nervous system (CNS) is the most dangerous and prognostic significance. They often fatal and takes a leading role in the future of children and maladjustment of severe disabling diseases. Introduction of innovative medical technologies in health care practice greatly enhances the study of the causes of many diseases and abnormalities in newborns and helps to clarify the etiology, pathogenetic mechanisms, clinical and morphological structure, as well as typical for different gestational age localization of brain damage. It is shown that the generalized disorder of lipid metabolism with the development membranodestruktive processes is closely correlated with the severity of hypoxic-ischemic lesions of the central nervous system. It was found that infants who underwent antenatal and / or intranatal hypoxia, there are significant transformation of lipid metabolism lead to changes in the composition of lipids of blood plasma and red blood cells (with the accumulation level of chaotropic fractions phospholipid bilayer membranes of red blood cells - Lizoform phospholipids and free fatty acids). The necessity inclusion complex therapy consequences of perinatal hypoxia drugs, which have antioxidant, antihypoxic activity and the ability to regulate lipid metabolism.

scholarly journals Congenital anomalies of the central nervous system: prevalence in a fetal medicine service in the Brazilian Midwest

2021 ◽  
Author(s):  
Carolina Leão de Moraes ◽  
Fernanda Sardinha de Abreu Tacon ◽  
Andréa de Faria Rezende Matos ◽  
Natália Cruz e Melo ◽  
Michelle Hermínia Mesquita de Castro ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prenatal Care ◽  
Pregnant Women ◽  
Congenital Anomalies ◽  
Fetal Medicine ◽  
Medicine Service ◽  
The Central Nervous System ◽  
Prospective Longitudinal ◽  
Cns Anomalies

Introduction: Approximately 21% of congenital anomalies (CA) involve the Central Nervous System (CNS), constituting one of the most common birth defects, affecting 1 to 10: 1,000 of live births. Objective: To analyze the prevalence of CNS anomalies diagnosed by obstetric ultrasound. Methods: Prospective longitudinal cohort study carried out in a public fetal medicine service in Goiânia with pregnant women who were attended in high-risk prenatal care. The patients were followed up during the ultrasound exams from March 2018 to March 2019. Results: 225 cases of pregnant women with ultrasound diagnoses of CA were surveyed during the investigated period. CNS anomalies were the most prevalent, being present in 34.22% (77/225) of the cases. The mean maternal age of pregnant women was 25.55 years and mean gestational age was 28.84 weeks. Hydrocephalus was identified in 23 pregnant women (29.87%), being the most prevalent CNS anomalie. Anencephaly was present in 24.68% (19/77) and holoprosencephaly in 18.18% (14/77). Other CA were also diagnosed (21/77), such as meningocele, spina bifida, acrania, among others. However, they showed a lower prevalence in relation to hydrocephalus, anencephaly and holoprosencephaly. Conclusion: The findings are essential for the planning and allocation of hospital resources and investment in health. Besides that, to adequate and specific prenatal care, is indispensable in the search for reducing the incidence of these malformations, morbidity and improving survival rates of the affected population.

scholarly journals Clinical and biochemical predictors of neurological disorders

2020 ◽  
Vol 4 (35) ◽  
pp. 34-39
Author(s):  
I. Yu. Serikova ◽  
G. I. Shumacher ◽  
E. N. Vorobyova ◽  
I. A. Batanina ◽  
R. I. Vorobyov
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Neurological Disorders ◽  
Protein S ◽  
Nerve Tissue ◽  
S 100 ◽  
The Central Nervous System ◽  
Peroxidation Processes ◽  
The City

The aim of this study is to identify clinical and biochemical predictors of neurological disorders in adolescents who have suffered mild perinatal damage of the central nervous system. We examined 120 adolescents (62 girls and 58 boys) aged 13–16 years, who were hospitalized in the city Children’s Neurological Department. It was found that adolescents with perinatal lesions of the central nervous system, activated lipid peroxidation processes and revealed an increase in the concentration of protein S 100, which in the future could lead to the development of neurodegeneration processes. In addition, a positive correlation between the lipid peroxidation processes nd the concentration of the nerve tissue damage marker was revealed. The results indicate that the level of neurospecific protein — protein S 100, parameters of the oxidant‑antioxidant system, perinatal factors can be used as predictors of chronic nervous tissue processes.

scholarly journals Follow-up of pregnant women with active cytomegalovirus infection

1999 ◽  
Vol 5 (5) ◽  
pp. 1049-1054
Author(s):  
H. Y. Al Ali ◽  
S. A. Yasseen ◽  
T. Y. Raof
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pregnant Women ◽  
Congenital Malformations ◽  
Cmv Infection ◽  
Serological Evidence ◽  
Congenital Cmv Infection ◽  
The Central Nervous System ◽  
Congenital Cmv

Pregnant women [60]with and without serological evidence of active cytomegalovirus [CMV]infection were followed until delivery to detect the incidence and types of overt congenital CMV infection in neonates in Mosul, Iraq. Infection was diagnosed by the detection of CMV-IgM, using ELISA. CMV-IgM was detected in cord blood samples of six [10%]overtly sick infants [with different congenital malformations]born to mothers with active CMV infection. Central nervous system abnormalities were detected in all six cases [two with microcephaly and four with hydrocephaly]. Congenital CMV infection should be suspected in infants born with congenital malformations, especially those of the central nervous system. The detection of a significant number of hydrocephalus cases in our study is notable

scholarly journals The influence of stress during pregnancy on the central nervous system of mother and her child

2021 ◽  
Vol 47 (3) ◽  
pp. 492-499
Author(s):  
Anna Kupryjaniuk ◽  
Michał Sobstyl
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prefrontal Cortex ◽  
Pregnant Women ◽  
Brain Research ◽  
Behavioral Therapy ◽  
Well Being ◽  
Anxiety And Depression ◽  
Pregnancy And Childbirth ◽  
The Central Nervous System

Pregnant women may experience high levels of stress, including those associated with finding oneself in a new reality. In addition, the new reality is the COVID-19 pandemic, which has contributed to the deterioration of the mental state of many people. Chronic stress can lead to neuroanatomical changes in the mother, but also in her baby. It leads to atrophy of neurons in the hippocampus and prefrontal cortex, and to the growth and enlargement of the amygdala, i.e. those structures that are responsible for emotions. The mother's emotions also shape the synapses in the fetus, and the neurotransmitters secreted by the mother modify the development of the baby's brain. Research is ongoing in many countries on the consequences of anxiety and depression in pregnant women during the COVID-19 pandemic. For this reason, it is important to take care of psychological well-being, for example by using the techniques of cognitive behavioral therapy. Support from relatives during pregnancy and childbirth is also an extremely important element in the proper development of the central nervous system of the mother and her child.

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