scholarly journals Effects of subchronic exposure manganese oxide nanoparticles on the central nervous system, lipid peroxidation and antioxidant enzymes in rats

2014 ◽  
pp. 66-77 ◽  
Author(s):  
N.V. Zaitseva ◽  
◽  
M.A. Zemlyanova ◽  
V.N. Zvezdin ◽  
Т.I. Akafyeva ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Antioxidant Enzymes ◽  
Manganese Oxide ◽  
Oxide Nanoparticles ◽  
Manganese Oxide Nanoparticles ◽  
Subchronic Exposure ◽  
The Central Nervous System

scholarly journals Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Functionalization for Biomedical Applications in the Central Nervous System

Materials ◽  
2019 ◽  
Vol 12 (3) ◽  
pp. 465 ◽  
Author(s):  
Shoeb Ansari ◽  
Eleonora Ficiarà ◽  
Federico Ruffinatti ◽  
Ilaria Stura ◽  
Monica Argenziano ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Close Link ◽  
Wide Range ◽  
Methods Of Synthesis ◽  
The Central Nervous System

Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range of applications. During recent years, one of the most challenging goals is the development of new strategies to finely tune the unique properties of MNPs, in order to improve their effectiveness in the biomedical field. This review provides an up-to-date overview of the methods of synthesis and functionalization of MNPs focusing on Iron Oxide Nanoparticles (IONPs). Firstly, synthesis strategies for fabricating IONPs of different composition, sizes, shapes, and structures are outlined. We describe the close link between physicochemical properties and magnetic characterization, essential to developing innovative and powerful magnetic-driven nanocarriers. In conclusion, we provide a complete background of IONPs functionalization, safety, and applications for the treatment of Central Nervous System disorders.

scholarly journals Clinical and biochemical predictors of neurological disorders

2020 ◽  
Vol 4 (35) ◽  
pp. 34-39
Author(s):  
I. Yu. Serikova ◽  
G. I. Shumacher ◽  
E. N. Vorobyova ◽  
I. A. Batanina ◽  
R. I. Vorobyov
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Neurological Disorders ◽  
Protein S ◽  
Nerve Tissue ◽  
S 100 ◽  
The Central Nervous System ◽  
Peroxidation Processes ◽  
The City

The aim of this study is to identify clinical and biochemical predictors of neurological disorders in adolescents who have suffered mild perinatal damage of the central nervous system. We examined 120 adolescents (62 girls and 58 boys) aged 13–16 years, who were hospitalized in the city Children’s Neurological Department. It was found that adolescents with perinatal lesions of the central nervous system, activated lipid peroxidation processes and revealed an increase in the concentration of protein S 100, which in the future could lead to the development of neurodegeneration processes. In addition, a positive correlation between the lipid peroxidation processes nd the concentration of the nerve tissue damage marker was revealed. The results indicate that the level of neurospecific protein — protein S 100, parameters of the oxidant‑antioxidant system, perinatal factors can be used as predictors of chronic nervous tissue processes.

Lipid Metabolism in Neurocognitive Disorders: Current Update

2021 ◽  
Author(s):  
Antonella Mandas
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Lipid Metabolism ◽  
Scientific Literature ◽  
Scientific Research ◽  
Neurocognitive Disorders ◽  
Lipid Homeostasis ◽  
The Central Nervous System ◽  
E4 Allele

The physiology and the pathology of the Central Nervous System (CNS) is very complex, and only by understanding it the scientific research might develop effective treatments. Neurocognitive Disorders, extremely diffused diseases, have a multifactorial aetiology, in which lipid homeostasis plays an important role, as known. The aim of this mini-review is focus on interesting recently published researches on the topic, in order to put together some pieces of the puzzle of such an enormous physiopathology chapter. After a brief introduction, we will describe important aspects of CNS lipid metabolism, then we will examine the conclusions of recent articles relating to lipid role in neurodegeneration. The recent scientific literature has strengthened the position of some well-known “biological agents” – i.e. lipid peroxidation and apolipoprotein E4 allele –but also detailed the importance of new promising diagnostic and therapeutic targets.

Age-related changes in lipid peroxidation in various structures of the central nervous system

2005 ◽  
Vol 31 (2) ◽  
pp. 214-220
Author(s):  
I. A. Volchegorskii ◽  
S. E. Shemyakov ◽  
I. B. Telesheva ◽  
N. V. Malinovskaya ◽  
V. V. Turygin
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Age Related ◽  
The Central Nervous System ◽  
Age Related Changes
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