Neurobiology of Learning and Memory in Mentally Fatigued Truck Drivers

2018 ◽  
Vol 3 (11) ◽  
Author(s):  
Felecia Jefferson ◽  
Redeshia Burks ◽  
Ivy Malone ◽  
Adelia Mckinley

Sleep is the normal rest of an organism. There are two types of sleep. REM and NREM. REM is considered the deep sleep and NREM is considered the lighter sleep. Sleep is also, organized by the brain. You also can sleep what you eat, meaning that, whatever you eat can affect the way you sleep. Memory is the ability to attain, store, and retain and recall information and past experiences in the human brain. Sleep affects learning and memory in a cause and effect situation, if one does not attain enough sleep, their memory or learning ability will not be sufficient. One can maintain healthy or improve their learning and memory function by eating healthy, exercising, keeping stress level low and improving sleep quality. College students can improve sleep quality by revising instead of cramming, being active on campus and stimulating their brains by learning new information.

2018 ◽  
Vol 4 (01) ◽  
Author(s):  
Felecia Jefferson ◽  
Redeshia Burks ◽  
Ivy Malone ◽  
Adelia Mckinley

Sleep is the normal rest of an organism. There are two types of sleep. REM and NREM. REM is considered the deep sleep and NREM is considered the lighter sleep. Sleep is also, organized by the brain. You also can sleep what you eat, meaning that, whatever you eat can affect the way you sleep. Memory is the ability to attain, store, and retain and recall information and past experiences in the human brain. Sleep affects learning and memory in a cause and effect situation, if one does not attain enough sleep, their memory or learning ability will not be sufficient. One can maintain healthy or improve their learning and memory function by eating healthy, exercising, keeping stress level low and improving sleep quality. College students can improve sleep quality by revising instead of cramming, being active on campus and stimulating their brains by learning new information.


2018 ◽  
Vol 3 (10) ◽  
Author(s):  
Felecia Jefferson ◽  
Redeshia Burks ◽  
Ivy Malone ◽  
Adelia Mckinley

Sleep is the normal rest of an organism. There are two types of sleep. REM and NREM. REM is considered the deep sleep and NREM is considered the lighter sleep. Sleep is also, organized by the brain. You also can sleep what you eat, meaning that, whatever you eat can affect the way you sleep. Memory is the ability to attain, store, and retain and recall information and past experiences in the human brain. Sleep affects learning and memory in a cause and effect situation, if one does not attain enough sleep, their memory or learning ability will not be sufficient. One can maintain healthy or improve their learning and memory function by eating healthy, exercising, keeping stress level low and improving sleep quality. College students can improve sleep quality by revising instead of cramming, being active on campus and stimulating their brains by learning new information.


2021 ◽  
Author(s):  
Maria Clara Lopes Rezende ◽  
Mariana Vanon Moreira ◽  
Bárbara Gomes Muffato ◽  
Yves Henrique Faria Dias ◽  
Ana Luíza Badini Tubenchlak ◽  
...  

Introduction: Alzheimer’s disease (AD) is the most common form of dementia, which has no cure and, also, effective therapies to prevent or slow the progression of AD remain elusive. Thus, it is necessary to find another way to treat this disease Objective: Investigate the impact of meditation on the cognitive function of patients with AD. Methods: In April 2021, a systematic review was carried out on MEDLINE using the descriptors: “Meditation” and “Alzheimer Disease” and their variations. Studies published in the last 10 years and in English were included. Results: Of the 40 articles found, four are part of this review. It was showed that meditation generates improvements in memory as it increases cerebral blood flow, stabilizes synapses and elevates important neurotransmitters. Aligned, it can improve sleep quality and retrospective memory function. Furthermore, daily practices help in neuropsychological conditions and generate beneficial changes in brain structure and function. Finally, it provokes changes in the brain network, such as the increased power of the theta band, involved in memory processes. Conclusion: The results imply a positive effect of meditation on patients with AD. However, further research is needed to confirm the validity of the results.


2019 ◽  
Vol 4 (1) ◽  

Sleep is an important factor in human life cycle. Many of the people are struggling from sleep disorders that may range from sleep deprivation to insomnia. Other major factor with respect to sleep is quality of sleep. It tends to happen with many of the people now a days that they get sleep for 6 to 8 hours but still they feel fatigue or sleepy throughout the day or even they are not satisfied with their sleep. Many people move towards the clinical/medical way to get good deep sleep like sleeping pills or tablets having alprazolam [1]. This may have seductive side effects throughout the day. Here in this paper we focus to improve sleep quality by maintain efficient hormonal profile of tryptophan i.e. melatonin through food based therapy to improve quality of sleep [2-4].


2018 ◽  
Vol 1 (4) ◽  
Author(s):  
Weidong Sun ◽  
Jian Zhou

Objective Proper participation in physical exercise can not only benefit people physically, but also promote people's psychological benefits. However, people are often only aware of the benefits of physical exercise, such as physical fitness, body shape and function, and ignore the psychological benefits caused by physical exercise. In recent years, more and more people pay attention to the positive psychological benefits of physical exercise on cognition. As the hope of the future of the country, the problem of physical health is widely concerned. To study the effect of physical exercise on children's cognitive function, and to analyze the possible biological mechanism of physical exercise affecting cognitive ability, and to provide a reference for promoting the good development of children's physique. Methods  Through the retrieval of Chinese knowledge network, Wanfang Data knowledge service platform, VVP cube knowledge discovery system, 100 chain database collection sports related research literature, collating literature information, in-depth integration of literature, analysis of the impact and mechanism of physical exercise on children's cognition. Results  (1) Physical exercise can improve the function of the brain, improve the efficiency of the brain, and enhance memory. Animal experiments have shown that physical exercise can enhance short-term memory by improving hippocampal function in rats. (2) Regular physical exercise can improve children's memory and executive function, and promote their cognitive function and academic performance. (3) The effect of physical exercise on specific cognitive function is in turn motor function, motor skills, academic performance, reasoning, reaction time and executive function. Physical exercise promotes cognitive performance by improving the goal of the brain pointing to the maintenance of processing, but physical exercise does not improve or slow down processing inhibition, and physical exercise is not related to processing inhibition. 30 minutes of acute physical exercise plays a significant role in maintaining children's attention. Acute high intensity physical exercise can improve selective attention and short-term memory tasks. In the experiment of the effect of one-off acute physical exercise on cognitive function, moderate intensity of heart rate variables and increased cognitive performance were related. For children with attention deficit hyperactivity disorder, physical exercise can improve their performance of executive function. (4) Physical exercise may affect the possible biological mechanisms of cognitive function: Firstly, exercise can improve the synthesis and secretion of neurotransmitters such as acetylcholine and dopamine, activate conduction pathways, improve synaptic transmission efficiency, and promote the development of learning and memory function. Secondly, exercise can increase brain derived neurotrophic factor (BDN F), release of nerve growth factors such as insulin-like growth factor --1 (IGF--1) and so on, thus promoting the development of learning and memory function. Again, physical exercise may also improve learning and memory performance by affecting the release of glucocorticoids. Then, physical exercise can enhance the gene expression in the brain area related to learning and memory. Finally, physical exercise may maintain and improve cognitive ability by improving the antioxidant capacity of brain tissue. Conclusions Physical exercise can promote the improvement of children's cognitive ability. The basic cognitive ability of children can be developed through physical exercise. The mechanism of the exercise can be explained by the changes of the brain nerve mechanism, such as increasing the brain capacity and increasing the flow velocity of the brain. The specific biological mechanism still needs to be studied.


2019 ◽  
Author(s):  
Krisztian Toth ◽  
Amanda C. Martyn ◽  
Natalia Bastrikova ◽  
Woojoo Kim ◽  
Ramona M. Rodriguiz ◽  
...  

AbstractG protein-coupled receptor kinase-interacting protein 2 (GIT2) and GIT1 are highly similar, sharing the same domain structure and many binding partners. The most important GIT partners are the p21-activated protein kinase-interacting exchange factor (PIX) proteins, since through homomeric and heteromeric interactions, GIT and PIX proteins form oligomeric GIT/PIX complexes. Oligomeric GIT/PIX complexes function both as regulators of small GTP-binding proteins and as scaffolds for signalling molecules, including p21-activated protein kinases (PAKs). Deficits in learning and memory have been demonstrated in GIT1 knockout mice, and it has been assumed that GIT2 also would affect learning and memory. Unexpectedly, we find that GIT2-deficient mice respond normally in multiple tests of learning and memory, and have normal hippocampal long-term potentiation. Further, we find no evidence that GIT2 regulates ADHD-like phenotypes. To investigate why GIT2 and GIT1 differ so markedly in the brain, we identified the major isoform of GIT2 in the brain as a previously uncharacterized splice variant, GIT2(ΔBCE). This variant cannot dimerize or form oligomeric complexes with PIX proteins, and is thus incapable of regulating PAK in synapses, compared to oligomeric GIT1/PIX complexes. Because localized activation of PAK in synapses is required for structural plasticity underlying cognitive performance, loss of monomeric GIT2(ΔBCE) in the brain does not influence these responses.


2020 ◽  
Author(s):  
Di Wu ◽  
Jay Prakash Prasad Kumal ◽  
Xiaodi Lu ◽  
Yixuan Li ◽  
Dongsheng Mao ◽  
...  

Abstract Background: There are increasing studies suggest that Traumatic Brain Injury(TBI) might be the cause of some neurodegenerative diseases, including Alzheimer’s Disease(AD). The mechanism of AD induced by TBI has also been elucidated from sorts of aspects. However, there are also researches which opponent to the viewpoint that TBI is the reason of AD. In this study, we investigate whether and how could TBI accelerated the Alzheimer’s-like pathology and cognitive dysfunction in APP/PS1 mice.Method: The traumatic brain injury model was established in adult male APP/PS1 and C57BL/6 mice. At the 29th and 30th day post-TBI, Novel object and novel position recognition test were performed to test the learning and memory function. After cognitive function test, all the mice were sacrificed with PBS perfusion to anatomize the brain for histopathological study. To determine whether the Alzheimer’s-like pathology and the synaptic function decline can be accelerated by TBI, HE staining, IF staining and IHC staining were performed to detect the cell density in the brain, the degree of Aβ-plaques deposition in the brain, and SYP expression in the brain. We also examined the activity and the phenotype of microglia by IF staining and western-blotting the after the 1st, 2nd, 3rd and 4th week of TBI.Result: In current study, we showed that, on the one hand, TBI impaired the hippocampal-dependent learning and memory, decreased the cell density in the brain, disturbed the synaptic function in the brain, aggravated Aβ-plaques deposition in the hippocampus. On the other hand, TBI also quickly activated microglia in the CNS and altered the phenotype of microglia polarizing to a pro-inflammatory direction. The duration of activation of microglia post-TBI can be at least 3 weeks. We also found that microglia activity was related to the deposition of Aβ-plaques in the specific region of hippocampus. Conclusion: Our experiment suggested that TBI accelerate the onset of cognitive dysfunction and Alzheimer’s-like pathology in APP/PS1 mouse model by altering microglia polarizing direction to mostly exhibiting pro-inflammatory phenotype.


2018 ◽  
Vol 5 (4) ◽  
pp. 126-134
Author(s):  
Aminollah Golrou ◽  
Ali Sheikhani ◽  
Ali Motie Nasrabadi ◽  
Mohammad Reza Saebipour

Background: One of the challenges today is that the quality of sleep has weakened by many external factors, which we are not even aware of and which directly affect sleep. Sleep quality has an essential role in maintaining the cognitive function and memory consolidation of individuals. So far, various studies have been done to improve the quality of sleep by using external electrical stimulation, vestibular and olfactory system stimulation. Methods: In this study, the increase in sleep quality was considered by simultaneous acoustic stimulation in a deep sleep to increase the density of slow oscillations. Slow oscillations are the important events recorded in electroencephalography (EEG) and hallmark deep sleep. Acoustic stimulation of pink noise with random frequency ranging from 0.8 to 1.1 Hz was used to improve sleep quality. Results: Eight healthy adults (mean age: 28.4±7.8 years) studied in 3 nights under 3 conditions: accommodation night, stimulation night (STIM) and no stimulation night (SHAM), in counterbalanced order. Significant characteristics of the objective and subjective quality of sleep have been extracted from the acquired EEG and compared in the last 2 nights. Also, the arousal and cyclic alternating pattern characteristics have been measured to assess sleep stability over 2 nights of STIM and SHAM. Conclusion: Our findings confirm this goal of the study that applying designed acoustic stimulation simultaneously in the slow wave sleep (SWS) stage increases the duration of deep sleep and ultimately improves overall sleep stability and quality. Keywords: Sleep quality enhancement; Acoustic stimulation; Slow wave sleep; CAP & arousals; Sleep stability; EEG


2019 ◽  
Vol 2 (2) ◽  
pp. 125-131
Author(s):  
Siti Muawanah ◽  
Futhri Rifa Zaimsyah ◽  
Nova Relida

Sleep is one of the needs of a baby or child that is as important as other primary needs. One way to fulfill your baby's sleep needs is by massage. Touch on the skin will stimulate blood circulation and will increase the oxygen wave energy that is more sent to the brain so that the circulation system and respiration spur better. Feeling comfortable and relaxed due to massage will improve sleep quality. In addition, it can increase the production of Asi, increase body weight, increase endurance, in infants 0-6 months. The purpose of this study is to prove that massage can improve the quality of sleep for babies 0-6 months. The method of dedication was carried out by tearing the hearts of the 13 people in one group and were intervened with infant massage. in normal infants 0-6 months. The conclusion of this service is that there is the effect of giving a baby massage to the sleep quality of a normal baby 0-6 months


Sign in / Sign up

Export Citation Format

Share Document