Exclusive Breastfeeding and the Impact on Neonatal Mortality of Low Birth Weight

Abstract Background Ghana did not meet the Millennium Development Goal 4 of reducing child mortality by two-thirds and may not meet SDG (2030). There is a need to direct scarce resources to mitigate the impact of the most important risk factors influencing high neonatal deaths. This study applied both spatial and non-spatial regression models to explore the differential impact of environmental, maternal, and child associated risk factors on neonatal deaths in Ghana. Methods The study relied on data from the Ghana Demographic and Health Surveys (GDHS) and the Ghana Maternal Health Survey (GMHS) conducted between 1998 and 2017 among 49,908 women of reproductive age and 31,367 children under five (GDHS-1998 = 3298, GDHS-2003 = 3844, GDHS-2008 = 2992, GDHS-2014 = 5884, GMHS-2017 = 15,349). Spatial Autoregressive Models that account for spatial autocorrelation in the data at the cluster-level and non-spatial statistical models with appropriate sampling weight adjustment were used to study factors associated with neonatal deaths, and a p-value less than 0.05 was considered statistically significant. Results Population density, multiple births, smaller household sizes, high parity, and low birth weight significantly increased the risk of neonatal deaths over the years. Among mothers who had multiple births, the risk of having neonatal deaths was approximately four times as high as the risk of neonatal deaths among mothers who had only single birth [aRR = 3.42, 95% CI: 1.63–7.17, p < 0.05]. Neonates who were perceived by their mothers to be small were at a higher risk of neonatal death compared to very large neonates [aRR = 2.08, 95% CI: 1.19–3.63, p < 0.05]. A unit increase in the number of children born to a woman of reproductive age was associated with a 49% increased risk in neonatal deaths [aRR = 1.49, 95% CI: 1.30–1.69, p < 0.05]. Conclusion Neonatal mortality in Ghana remains relatively high, and the factors that predisposed children to neonatal death were birth size that were perceived to be small, low birth weight, higher parity, and multiple births. Improving pregnant women’s nutritional patterns and providing special support to women who have multiple deliveries will reduce neonatal mortality in Ghana.

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The impact of pregnancy induced hypertension on low birth weight in Ethiopia: systematic review and meta-analysis

Italian Journal of Pediatrics ◽

10.1186/s13052-020-00926-0 ◽

2020 ◽

Vol 46 (1) ◽

Author(s):

Temesgen Getaneh ◽

Ayenew Negesse ◽

Getenet Dessie ◽

Melaku Desta

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Neonatal Mortality ◽

Meta Analysis ◽

Cochrane Library ◽

Significant Heterogeneity ◽

Pregnancy Induced Hypertension ◽

Pooled Prevalence ◽

Induced Hypertension ◽

The Impact

Abstract Background Even though neonatal mortality reduction is the major goal needed to be achieved by 2030, it is still unacceptably high especially in Ethiopia. In the other hand, low birth weight is the major cause of neonatal mortality and morbidity. More than 10 millions of low birth weight infants occurred as a result of pregnancy induced hypertension. However, in Ethiopia the association between low birth weight and pregnancy induced hypertension was represented with un-updated, inconclusive and different studies. Therefore, this review aimed to estimate the overall pooled impact of pregnancy induced hypertension on low birth weight and its association in Ethiopia. Methods articles searched on PubMed/Medline, EMBASE, CINAHL, Cochrane library, Google, Google Scholar and local shelves. Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was applied for critical appraisal. The I2 statistic was computed to check the presence of heterogeneity. Publication bias was evaluated using funnel plot asymmetry and Egger’s test. A random effect model was used to estimate the pooled prevalence of low birth weight. Result From the total 131 identified original articles, 25 were eligible and included for the final analysis. The overall pooled prevalence of low birth weight among women who had pregnancy induced hypertension in Ethiopia was 39.7% (95% CI: 33.3, 46.2). But, I2 statistic estimation evidenced significant heterogeneity across included studies (I2 = 89.4, p < 0.001). In addition, the odds of having low birth weight newborns among women who had pregnancy induced hypertension was 3.89 times higher compared to their counterparts (OR = 3.89, 95% CI: 2.66, 5.69). Conclusion The pooled prevalence of low birth weight among women who had pregnancy induced hypertension was more than two times higher than the pooled estimate of low birth weight among all reproductive aged women. The odds of low birth weight also increased nearly four times among women with pregnancy induced hypertension than normotensive women. Therefore, health policies which provide better and quality antenatal care with more oriented on importance of early detection and management of pregnancy induced hypertension should be implemented.

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Risk of Low Birth Weight According to Household Composition in Brussels and Montreal: Do Income Support Policies Variations Explain the Differences Observed between Both Regions?

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18157936 ◽

2021 ◽

Vol 18 (15) ◽

pp. 7936

Author(s):

Mouctar Sow ◽

Myriam De Spiegelaere ◽

Marie-France Raynault

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Household Composition ◽

Income Support ◽

Welfare Benefits ◽

Number Of Children ◽

Households With Children ◽

Vulnerable Households ◽

Welfare Families ◽

The Impact

Variations in social policy between countries provide opportunities to assess the impact of these policies on health inequities. This study compares the risk of low birth weight in Brussels and Montreal, according to household composition, and discusses the impact of income support policies. For each context, we estimated the impact of income support policies on the extent of poverty of welfare recipients, using the model family method. Based on the differences found, we tested hypotheses on the association between low birth weight and household composition, using administrative data from the birth register and social security in each region. The extent of poverty of welfare families differs according to household composition. In Quebec, the combination of low welfare benefits and larger family allowances widens the gap between households with children and those without children. The risk of LBW also differs between these two contexts according to the number of children. Compared to children born into large welfare families, first-born children are more at risk in Montreal than in Brussels. In addition to the usual comparative studies on the topic, our study highlights the importance of an evaluative perspective that considers the combination of different types of income support measures to better identify the most vulnerable households.

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Amikacin or Vancomycin Exposure Alters the Postnatal Serum Creatinine Dynamics in Extreme Low Birth Weight Neonates

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18020662 ◽

2021 ◽

Vol 18 (2) ◽

pp. 662

Author(s):

Tamara van Donge ◽

Anne Smits ◽

John van den Anker ◽

Karel Allegaert

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Serum Creatinine ◽

Potential Effect ◽

Extremely Low Birth Weight ◽

Treatment Modalities ◽

Antibiotic Exposure ◽

Sensitive Tool ◽

Elbw Neonates ◽

The Impact

Background: Disentangling renal adverse drug reactions from confounders remains a major challenge to assess causality and severity in neonates, with additional limitations related to the available tools (modified Kidney Disease Improving Global Outcome, or Division of Microbiology and Infectious Diseases pediatric toxicity table). Vancomycin and amikacin are nephrotoxic while still often prescribed in neonates. We selected these compounds to assess their impact on creatinine dynamics as a sensitive tool to detect a renal impairment signal. Methods: A recently developed dynamical model that characterized serum creatinine concentrations of 217 extremely low birth weight (<1000 g, ELBW) neonates (4036 observations) was enhanced with data on vancomycin and/or amikacin exposure to identify a potential effect of antibiotic exposure by nonlinear mixed-effects modelling. Results: Seventy-seven percent of ELBW patients were exposed to either vancomycin or amikacin. Antibiotic exposure resulted in a modest increase in serum creatinine and a transient decrease in creatinine clearance. The serum creatinine increase was dependent on gestational age, illustrated by a decrease with 56% in difference in serum creatinine between a 24 or 32-week old neonate, when exposed in the 3rd week after birth. Conclusions: A previously described model was used to explore and quantify the impact of amikacin or vancomycin exposure on creatinine dynamics. Such tools serve to explore minor changes, or compare minor differences between treatment modalities.

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Low Birth Weight Prevalence in Children Diagnosed with Neurodevelopmental Disorders in Dubai

Global Pediatric Health ◽

10.1177/2333794x211031782 ◽

2021 ◽

Vol 8 ◽

pp. 2333794X2110317

Author(s):

Faisal A. Nawaz ◽

Meshal A. Sultan

Keyword(s):

Risk Factors ◽

Birth Weight ◽

Mental Disorders ◽

Low Birth Weight ◽

Neurodevelopmental Disorders ◽

Autism Spectrum ◽

High Birth Weight ◽

Perinatal Risk Factors ◽

Perinatal Risk ◽

The Impact

The aim of this study is to evaluate the prevalence of low birth weight and other perinatal risk factors in children diagnosed with neurodevelopmental disorders. This is one of the first studies in the Arabian Gulf region focused on the contribution of these factors toward the development of various disorders such as attention-deficit/hyperactivity disorder, autism spectrum disorder, and other mental disorders. This descriptive study was based on qualitative data analysis. We reviewed retrospective information from the electronic medical records of 692 patients in Dubai, United Arab Emirates. The prevalence of low birth weight in children with mental disorders was significantly higher as compared to the general population (16% vs 6% respectively). Furthermore, other risk factors, including high birth weight and preterm birth were noted to have a significant association with neurodevelopmental disorders. Future research on the impact of perinatal risk factors will contribute to advancement of early intervention guidelines.

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Leminorella sepsis in very low birth weight neonate as cause of neonatal mortality

The Journal of Maternal-Fetal & Neonatal Medicine ◽

10.1080/14767058.2016.1199678 ◽

2016 ◽

Vol 30 (9) ◽

pp. 1057-1059 ◽

Cited By ~ 2

Author(s):

Deepak Sharma ◽

Ankur Patel ◽

Priyanka Soni ◽

Sweta Shastri ◽

Ravinder Singh

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Neonatal Mortality ◽

Very Low Birth Weight ◽

Birth Weight Neonate

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The Impact of Low Birth Weight, Perinatal Conditions, and Sociodemographic Factors on Educational Outcome in Kindergarten

PEDIATRICS ◽

10.1542/peds.104.6.e74 ◽

1999 ◽

Vol 104 (6) ◽

pp. e74-e74 ◽

Cited By ~ 56

Author(s):

M. B. Resnick ◽

R. V. Gueorguieva ◽

R. L. Carter ◽

M. Ariet ◽

Y. Sun ◽

...

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Sociodemographic Factors ◽

Educational Outcome ◽

The Impact

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The impact of air pollution on low birth weight and infant mortality

Reviews on Environmental Health ◽

10.1515/reveh-2013-0007 ◽

2013 ◽

Vol 28 (2-3) ◽

Cited By ~ 2

Author(s):

Zoheir Ezziane

Keyword(s):

Air Pollution ◽

Birth Weight ◽

Infant Mortality ◽

Low Birth Weight ◽

The Impact

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HUBUNGAN BBLR DAN ASI EKSLUSIF DENGAN KEJADIAN STUNTING DI PUSKESMAS LIMA PULUH PEKANBARU

Jurnal Endurance ◽

10.22216/jen.v3i1.1767 ◽

2018 ◽

Vol 3 (1) ◽

pp. 131

Author(s):

Lidia Fitri

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Exclusive Breastfeeding ◽

Health Centre ◽

Sampling Technique ◽

P Value ◽

Not Given ◽

Cross Sectional ◽

Analysis Study

Stunting is one of the long-term indicators for malnutrition. Stunting prevalence in Indonesia about 37.2%. Babies born with low birth weight is 10.2% and the achievement of exclusive breastfeeding is 30.2%. Survey in Limapuluh Health Centre Pekanbaru, from 18 children who perform measurements, obtained 13 infants suffered stunting. The result of interviews showed that three of them were born with low birth weight (BBLR) and five are not given exclusive breastfeeding. This research is to find-out the correlation between low birth weight (BBLR) and exclusive breastfeeding with stunting in Limapuluh Health Centre Pekanbaru in 2017. This study was a quantitative analysis study used cross sectional strategy. Population consists of 300 people, sample consists of 75 people by accidental sampling technique. Analysis using univariat and bivariate. The result were 25 infant (33,3%) are stunting, 22 infant (29,3%) with low birth weight (BBLR) and not given exclusive breastfeeding are 55 infant (73,3%). There was a significant association between low birth weight (BBLR) with stunting was obtained p value 0.000 and association between exclusive breastfeeding with stunting was obtained p value 0.021 its mean p<0,05. There is a relationship between BBLR and exclusive breastfeeding with stunting events, the Ha accepted. Stunting merupakan salah satu indikasi buruknya status gizi pada anak. Prevalensi stunting di Indonesia sebesar 37,2%. Angka kejadian bayi dengan BBLR sebanyak 10,2% dan pencapaian ASI ekslusif 30,2%. Survey di Puskesmas Lima Puluh kota Pekanbaru Provinsi Riau didapatkan dari 18 orang balita yang di ukur, 13 orang diantaranya mengalami stunting. Hasil wawancara memperlihatkan bahwa 3 orang diantaranya lahir dengan BBLR dan 5 orang tidak diberikan ASI ekslusif. Tujuan penelitian untuk mengetahui hubungan berat badan lahir rendah (BBLR) dan ASI ekslusif dengan kejadian stunting di Puskesmas Lima Puluh Pekanbaru. Jenis penelitian analitik kuantitatif dengan desain cross sectional. Populasi berjumlah 300 orang balita, sampel 75 responden dengan teknik accidental sampling. Analisis data secara univariat dan bivariat. Hasil penelitian diperoleh sebanyak 25 orang (33,3%) balita mengalami stunting, balita dengan BBLR sebanyak 22 orang (29,3%) dan yang tidak diberikan ASI ekslusif sebanyak 55 orang (73,3%). Ada hubungan yang bermakna antara berat badan lahir rendah (BBLR) dengan kejadian stunting dimana p value 0.000 dan terdapat hubungan antara pemberian ASI ekslusif dengan kejadian stunting diperoleh nilai p value 0.021 artinya p<0,05. Dapat disimpulkan terdapat hubungan antara BBLR dan ASI eklusif dengan kejadian stunting, maka Ha diterima.

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