scholarly journals CURRENT COMPUTER TECHNOLOGIES IN THE DIAGNOSIS OF TRACHEOMALACIA IN PATIENTS WITH CICATRICIAL TRACHEAL STENOSIS IN THE PERIOPERATIVE PERIOD

2018 ◽  
Vol 99 (4) ◽  
pp. 197-203
Author(s):  
I. M. Koroleva ◽  
M. A. Mishchenko
Keyword(s):  
Tracheal Stenosis ◽  
Perioperative Period ◽  
Control Group ◽  
Mri Findings ◽  
Endoscopic Method ◽  
Clinically Significant ◽  
Magnetic Resonance Imaging Mri ◽  
Sensitivity Specificity ◽  
Diagnostic Capabilities

Objective: to analyze current radiodiagnostic techniques in identifying tracheomalacia (TM) and estimating its severity and extent in patients with cicatricial tracheal stenosis (CTS) and to determine the important characteristics of TM according to follow-up multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) findings.Material and methods. The investigation included the results of examining 94 patients, 81 of whom were diagnosed with CTS. To analyze the efficiency of the studies, the patients were divided into three groups; a control group of patients was formed. The diagnosis of TM was verified by clinical examination, instrumental diagnosis, MSCT and MRI studies, and intraoperative revision. The patients’ postoperative features were taken into consideration. Diagnostic performance measures, such as sensitivity, specificity, and accuracy, were calculated. Static radiation techniques (MSCT and MRI) and follow-up procedures (fMSCT and fMRI) were compared.Results. The follow-up procedures were proven to be twice as informative for the detection of the symptoms of TM as the endoscopic method that is considered the main method for the diagnosis of pathological tracheal changes. The diagnostic capabilities of MSCT, fMSCT, MRI, and fMRI were determined; criteria for identifying TM were formulated. The use of the follow-up procedures to identify clinically significant TM in patients with CTS could radically alter surgical tactic in 36.9% of cases.Conclusion. The proposed algorithm for examination of patients with CTS, which includes follow-up radiation procedures to evaluate the functional state of the tracheal wall, makes it possible to determine an optimal treatment policy and to significantly reduce the risks of complications and disease recurrences.

New frontiers ahead focal therapy postoperative follow-up: What is the real role of MRI in this setting?

2017 ◽  
Vol 35 (6_suppl) ◽  
pp. e539-e539
Author(s):  
Igor Nunes-Silva ◽  
Eric Barret ◽  
Mohammed Baghdadi ◽  
Victor Srougi ◽  
Silvia Garcia Barreras ◽  
...  
Keyword(s):  
Likelihood Ratio ◽  
Group Analysis ◽  
Focal Therapy ◽  
Primary Treatment ◽  
Matched Pair ◽  
Mri Findings ◽  
Predictive Values ◽  
Magnetic Resonance Imaging Mri ◽  
Sensitivity Specificity

e539 Background: Magnetic resonance imaging (MRI) plays an important role as a treatment-monitoring tool along focal therapy (FT) follow-up. This is the first study to assess MRI ability to correctly predict prostate cancer (PCa) local T-stage in the FT postoperative scenario. We aimed to describe MRI effectiveness in predicting upstaging in two groups of men: 1) men who failure after primary FT and then underwent salvage robotic-assisted radical prostatectomy (S-RARP) and 2) men who underwent RARP as primary treatment (P-RARP). Methods: Prospective data of 2775 men underwent RARP for localized PCa from 2000 to 2016 were reviewed. Twenty-two men underwent S-RARP after FT failure (S-RARP group). Total 2750 underwent RARP as first treatment. Matched-pair 1:2 selection of 44 out of 2750 patients by age defined primary RARP group (P-RARP). All patients underwent MRI immediately before RARP. MRI findings were confronted with final surgical pathology. Primary endpoint: sensitivity, specificity, positive and negative predictive values; positive (+LR) and negative (-LR) likelihood ratio regarding upstaging analysis on S-RARP. Secondary endpoint: same effectiveness analysis on P-RARP. Results: Preoperative MRI failed in predicting upstaging in 80% versus 91.7% of patients (p = 0.515) that presented final pathological status ≥ pT3a on S-RARP and P-RARP groups, respectively. On the other hand, when final pathology described a localized disease T2a-T2c, MRI correctly predicted the final pathological status in 81.8% versus 95.2% of patients (p = 0.27) on S-RARP and P-RARP groups, respectively. Between-group analysis, showed sensitivity and specificity rates of 20% versus 8.33% and 81.8% versus 95.23%, respectively; Positive and negative predictive values of 33.33% versus 50% and 69.23% versus 64.51%, respectively; Positive (+LR) and negative (-LR) likelihood ratio of 1.1 versus 1.74 and 0.98 versus 0.96, respectively. Conclusions: MRI has shown to be a weak diagnostic tool for predicting extra-prostatic disease along FT follow-up. Urologists may be warned about the risk of underdiagnosis and undertreatment in patients presenting failure after FT.

Accuracy of Rotator Cuff Tears and Tendinosis Diagnoses on Shoulder Ultrasound Performed by a Short-experienced Operator

2018 ◽  
Vol 1 ◽  
pp. 9
Author(s):  
Harshad Arvind Vanjare ◽  
Jyoti Panwar
Keyword(s):  
Rotator Cuff ◽  
Negative Predictive Value ◽  
Rotator Cuff Tear ◽  
Predictive Value ◽  
Rotator Cuff Tears ◽  
Mri Findings ◽  
Cuff Tear ◽  
Experienced Operator ◽  
Magnetic Resonance Imaging Mri ◽  
Sensitivity Specificity

Objective The objective of the study was to assess the accuracy of ultrasound examination for the diagnosis of rotator cuff tear and tendinosis performed by a short experienced operator, compared to magnetic resonance imaging (MRI) results. Method A total of 70 subjects suspected to have rotator cuff tear or tendinosis and planned for shoulder MRI were included in the study. Shoulder ultrasound was performed either before or after the MRI scan on the same day. Ultrasound operator had a short experience in performing an ultrasound of the shoulder. Ultrasound findings were correlated to MRI findings. Results Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for the diagnosis of tendinosis were 58%, 84%, 63%, 80%, and 75%, respectively, and it was 68%, 91%, 73%, 88%, and 85%, respectively, for the diagnosis of rotator cuff tear. Conclusions Sensitivity for diagnosing rotator cuff tear or tendinosis was moderate but had a higher negative predictive value. Thus, the ultrasound operator with a short experience in performing shoulder ultrasound had moderate sensitivity in diagnosing tendinosis or tears; however, could exclude them with confidence.

scholarly journals Evaluation of the ischiofemoral space: a case-control study

2019 ◽  
Vol 52 (4) ◽  
pp. 237-241 ◽  
Author(s):  
Antônio Augusto Guimarães Barros ◽  
Fernanda Bretz Gomes dos Santos ◽  
Carlos César Vassalo ◽  
Lincoln Paiva Costa ◽  
Sérgio Gonçalves Pereira Couto ◽  
...  
Keyword(s):  
Hip Joint ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Clinical Test ◽  
Mri Findings ◽  
Ischiofemoral Space ◽  
Magnetic Resonance Imaging Mri ◽  
Control Study ◽  
Quadratus Femoris

Abstract Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip joint. The mean age was 47.3 ± 14.0 years (range, 22-76 years), and 33 (66%) of the patients were women. A diagnosis of IFI was made in 6 patients (12%), all of whom were female. On average, IFS and QFS were significantly smaller in IFI group than in control group (11.1 ± 2.7 mm versus 27.5 ± 6.5 mm and 5.3 ± 1.8 mm versus 18.8 ± 4.8 mm, respectively; p < 0.001 for both). Conclusion: Results of specific clinical tests and MRI findings indicate that the IFS and QFS are significantly reduced in patients with IFI.

scholarly journals THU0487 DIAGNOSTIC DILEMMA: WHICH CLINICAL TEST IS MOST ACCURATE FOR DIAGNOSING SUPRASPINATUS MUSCLE TEARS AND TENDINOSIS?

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 481.3-481
Author(s):  
E. Balevi Batur ◽  
Z. Bekin Sarikaya ◽  
M. E. Kaygisiz ◽  
İ. Albayrak Gezer ◽  
F. Levendoğlu
Keyword(s):  
Shoulder Pain ◽  
Lower Sensitivity ◽  
Clinical Test ◽  
Clinical Tests ◽  
Mri Findings ◽  
Diagnostic Dilemma ◽  
Test Drop ◽  
Magnetic Resonance Imaging Mri ◽  
Sensitivity Specificity ◽  
Higher Sensitivity

Background:Supraspinatus tears and tendinosis are the most common pathology that cause shoulder pain to approximately half of the patients presenting clinically.1Objectives:To investigate the diagnostic accuracy of five clinical tests in the diagnosis of supraspinatus tears and tendinosis compared with magnetic resonance imaging (MRI).Methods:A total of 116 painful shoulders of 106 consecutive patients were examined. Patients were assessed using the most commonly used special clinical tests including the Jobe test (empty can), Neer test, drop arm test, Hawkins test and full can tests to identify supraspinatus tears and tendinosis. A visual analogue scale (VAS) was used for pain detection, and the Shoulder Pain and Disability Index (SPADI) questionnaire was administered. MRI examinations were performed on 1.5 Tesla MR system and images were assessed by a blinded radiologist. The primary outcomes were to determine the sensitivity, specificity, and accuracy of the five clinical tests, and to establish their correlation with MRI for supraspinatus tears and tendinosis.Results:The mean age was 55.10 ± 10.20 years, and 32.08% of the patients were female. The Hawkins test had a higher sensitivity and accuracy in tears (sensitivity 89.66%, accuracy 56.03%, respectively) and higher sensitivity in tendinosis (79.07%). The drop arm test had a lower sensitivity but higher specificity in both tendinosis and tears (sensitivity 0%, 12.07%, respectively, and specificity 87.67%, 96.5%, respectivelyConclusion:The Hawkins test was the most sensitive in both supraspinatus tendinosis and tears compared with MRI findings.References:[1]Yamaguchi K, Ditsios K, Middleton WD, Hildebolt CF, Galatz LM, Teefey SA,The demographic and morphological features of rotator cuff disease. A comparison of asymptomatic and symptomatic shoulders. J Bone Joint Surg Am, 2006. 88(8): p. 1699-704.Disclosure of Interests: :None declared

scholarly journals A case of chronic progressive Lyme encephalitis as a manifestation of late Lyme neuroborreliosis

2014 ◽  
Vol 6 (4) ◽  
Author(s):  
Vivek Verma ◽  
Matthew Roman ◽  
Disha Shah ◽  
Marina Zaretskaya ◽  
Mohamed H. Yassin
Keyword(s):  
White Matter ◽  
Short Term Memory ◽  
Treatment Options ◽  
Chronic Fatigue ◽  
Short Term ◽  
Mri Findings ◽  
White Matter Changes ◽  
Neurological Improvement ◽  
Magnetic Resonance Imaging Mri

A 54-year-old female living in Europe presented with gait ataxia, dizziness, and bilateral hearing loss. Magnetic resonance imaging (MRI) revealed non-specific white matter changes. The patient’s condition gradually deteriorated over two years without diagnosis. The patient continued to decline cognitively and neurologically with worsening ataxia and upper motor neuron signs. Repeat MRI showed worsening white matter changes. Lumbar puncture, not previously done, showed positive Lyme testing. Treatment with intravenous ceftriaxone resulted in marked neurological improvement. Four years after symptom, the patient has short-term memory deficits and chronic fatigue, but is otherwise neurologically, cognitively, and functionally intact. Follow up MRI findings remain largely unchanged. Because cases of intraparenchymal or encephalopathic neuroborreliosis in America are lacking, so are treatment options. We present a rare case and discuss our experience with antibiotic treatment. This case lends evidence to define optimal treatment of this disease, imperative for hastening neurological recovery.

The Syndrome of Spontaneous Intracranial Hypotension

Cephalalgia ◽  
1999 ◽  
Vol 19 (2) ◽  
pp. 80-87 ◽  
Author(s):  
CP O'Carroll ◽  
M Brant-Zawadzki
Keyword(s):  
Intracranial Hypotension ◽  
Spontaneous Intracranial Hypotension ◽  
Subdural Effusion ◽  
Resonance Imaging ◽  
Mri Findings ◽  
The Past ◽  
Downward Displacement ◽  
Prior Literature ◽  
Magnetic Resonance Imaging Mri

The authors report four cases of headache and other symptomatology related to the syndrome of intracranial hypotension. They were seen in a routine clinical practice over the past 3 years. The clinical features, magnetic resonance imaging (MRI) findings, and follow-up of these patients are described. Review of the prior literature on the topic is also included. All four patients presented with orthostatic headache syndrome. Three of the four demonstrated diffuse leptomeningeal thickening and enhancement on MRI studies. One subsequently developed a subdural effusion. One patient demonstrated downward displacement of the posterior fossa initially, which resolved on follow-up MRI scanning. Possible pathophysiologies of the syndrome are discussed.

scholarly journals Prevention Across the Spectrum: a randomized controlled trial of three programs to reduce risk factors for both eating disorders and obesity

2014 ◽  
Vol 45 (9) ◽  
pp. 1811-1823 ◽  
Author(s):  
S. M. Wilksch ◽  
S. J. Paxton ◽  
S. M. Byrne ◽  
S.B. Austin ◽  
S. A. McLean ◽  
...  
Keyword(s):  
Risk Factors ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Control Group ◽  
Obesity Risk ◽  
Randomized Controlled ◽  
Obesity Risk Factors ◽  
Clinically Significant ◽  
Perceived Pressure

BackgroundA randomized controlled trial of three school-based programs and a no-intervention control group was conducted to evaluate their efficacy in reducing eating disorder and obesity risk factors.MethodA total of 1316 grade 7 and 8 girls and boys (mean age = 13.21 years) across three Australian states were randomly allocated to: Media Smart; Life Smart; the Helping, Encouraging, Listening and Protecting Peers (HELPP) initiative; or control (usual school class). Risk factors were measured at baseline, post-program (5 weeks later), and at the 6- and 12-month follow-ups.ResultsMedia Smart girls had half the rate of onset of clinically significant concerns about shape and weight than control girls at the 12-month follow-up. Media Smart and HELPP girls reported significantly lower weight and shape concern than Life Smart girls at the 12-month follow-up. Media Smart and control girls scored significantly lower than HELPP girls on eating concerns and perceived pressure at the 6-month follow-up. Media Smart and HELPP boys experienced significant benefit on media internalization compared with control boys and these were sustained at the 12-month follow-up in Media Smart boys. A group × time effect found that Media Smart participants reported more physical activity than control and HELPP participants at the 6-month follow-up, while a main effect for group found Media Smart participants reported less screen time than controls.ConclusionsMedia Smart was the only program to show benefit on both disordered eating and obesity risk factors. Whilst further investigations are indicated, this study suggests that this program is a promising approach to reducing risk factors for both problems.

scholarly journals Anti-Vascular Endothelial Growth Factor Therapy as an Adjunct to Diabetic Vitrectomy

2021 ◽  
Vol 15 (1) ◽  
pp. 137-143
Author(s):  
Mushfig Karimov ◽  
Lala Akhundova
Keyword(s):  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Postoperative Period ◽  
Early Postoperative Period ◽  
Vitreous Cavity ◽  
Control Group ◽  
Diabetic Vitrectomy ◽  
Clinically Significant ◽  
Bevacizumab Injection

Introduction: The purpose of this work is to study the efficacy of the preoperative intravitreal administration of bevacizumab as an adjunct to vitrectomy in patients with Proliferative Diabetic Retinopathy (PDR). Methods: This retrospective comparative study was performed on 118 eyes (118 patients) with proliferative diabetic retinopathy (PDR), which underwent vitrectomy surgery at the Department of Diabetic Eye Disease at Zarifa Aliyeva National Ophthalmology Centre (Baku, Azerbaijan) in 2015-2019. The main group (the bevacizumab group) included 48 eyes with PDR that received intravitreal administration of bevacizumab (Avastin; Genentech Inc., USA) within one week before vitrectomy; the control group included 70 eyes that did not receive a bevacizumab injection for at least 3 months before the vitrectomy. The minimum follow-up was 12 months. Results: In both groups, complete retinal attachment after primary vitrectomy was achieved in all eyes (100%). Clinically significant intraoperative haemorrhage was observed in the preoperative bevacizumab injection group in 31.2% and the control group- 51.4%, p = 0.030. The preoperative bevacizumab injection reduced the risk of clinically significant haemorrhage by 2.3 times and the need for endodiathermy by 2.7 times (p = 0.031 and p = 0.024, respectively). Early vitreous cavity haemorrhage was observed in 15.0% in the bevacizumab group and in 35.5% in the control group (p = 0.038). The preoperative injection of bevacizumab before vitrectomy reduced the risk of vitreous cavity haemorrhage in the early postoperative period by 3.0 times (p = 0.036). Conclusion: The preoperative use of bevacizumab as an adjunct to diabetic vitrectomy can help reduce the incidence of intraoperative and early postoperative vitreous cavity haemorrhage, which leads to better functional results in the early postoperative period. Over the long-term follow-up period, the effect of the preoperative bevacizumab injections decreases.

scholarly journals Improved Cartilage Quality on Delayed Gadolinium-Enhanced MRI of Hip Cartilage after Subchondral Drilling of Acetabular Cartilage Flaps in Femoroacetabular Impingement Surgery at Minimum 5-Year Follow-Up

Cartilage ◽  
2020 ◽  
pp. 194760352094124
Author(s):  
Florian Schmaranzer ◽  
Pascal C. Haefeli ◽  
Emanuel F. Liechti ◽  
Markus S. Hanke ◽  
Moritz Tannast ◽  
...  
Keyword(s):  
Femoroacetabular Impingement ◽  
Mr Arthrography ◽  
Additional Treatment ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Study Group ◽  
Acetabular Cartilage ◽  
Significant Difference ◽  
Magnetic Resonance Imaging Mri

Objective To assess whether subchondral drilling of acetabular cartilage flaps during femoroacetabular impingement (FAI) surgery improves (1) acetabular dGEMRIC indices and (2) morphologic magnetic resonance imaging (MRI) scores, compared with hips in which no additional treatment of cartilage lesions had been performed; and (3) whether global dGEMRIC indices and MRI scores correlate. Design Prospective cohort study of consecutive patients with symptomatic FAI treated with open surgery between 2000 and 2007. Patients with subchondral drilling of acetabular cartilage flaps were allocated to the study group, those without drilling to the control group. All patients underwent indirect 3-T MR arthrography to assess cartilage quality by dGEMRIC indices and a semiquantitative morphologic MRI score at minimum 5 years after surgery. dGEMRIC indices and morphologic MRI scores were compared between and among groups using analysis of covariance/paired t tests. Results No significant difference was found between the global dGEMRIC indices of the study group (449 ± 147 ms, 95% CI 432-466 ms) and the control group (428 ± 143 ms, 95% CI 416-442 ms; P = 0.235). In regions with cartilage flaps, the study group showed higher dGEMRIC indices (472 ± 160 ms, 95% CI 433-510 ms) compared with the control group (390 ± 122 ms, 95% CI 367-413 ms; P < 0.001). No significant differences were found for the morphologic MRI scores. A strong inversely linear correlation between the dGEMRIC indices and the morphologic MRI scores ( r = −0.727, P < 0.001) was observed. Conclusions Treatment of acetabular cartilage flaps with subchondral drilling leads to better cartilage quality in regions with cartilage flaps at minimum 5 years of follow-up.

Treatment of Carotid Restenosis Using Transcarotid Revascularization

2020 ◽  
Vol 54 (5) ◽  
pp. 436-440
Author(s):  
S. Keisin Wang ◽  
Alexander H. King ◽  
Vikram S. Kashyap ◽  
Mazin I. Foteh ◽  
Ravi N. Ambani ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Perioperative Period ◽  
Carotid Revascularization ◽  
Stent Restenosis ◽  
Postoperative Hematoma ◽  
United States Food ◽  
Hospital Systems ◽  
States Food ◽  
Clinically Significant

Objective: Transcarotid artery revascularization (TCAR) using the ENROUTE Neuroprotection System (Silk Road Medical) is a United States Food and Drug Administration–approved treatment modality for stroke risk reduction in the setting of carotid artery stenosis. The goal of this investigation was to define the real-world outcomes associated with the application of this technique to patients presenting with restenosis after previous carotid endarterectomy (CEA) or transfemoral carotid artery stenting (TF-CAS). Methods: Retrospective review of prospectively maintained institutional databases capturing all nontrial TCARs performed between August 2013 and July 2018 using the ENROUTE Neuroprotection System was completed at 3 unaffiliated hospital systems and unified for descriptive outcomes analysis. Results: During the study period, 237 combined TCARs were performed at our respective institutions. Of these procedures, 55 stents were implanted for the indication of restenosis after previous carotid revascularization (47 CEA, 8 TF-CAS). Within the 30-day perioperative period, we observed no ipsilateral strokes or deaths; one patient experienced perioperative myocardial infarction (MI; 1.8%). We noted a 4.8% incidence of postoperative hematoma, but none of these events were clinically significant as no reinterventions were performed in any of the 55 patients. Additionally, we did not observe any cases of stent thrombosis or pulmonary embolus. Mean length of stay was 2.2 ± 2.8 days. Our mean follow-up duration was 15.0 ± 9.2 months. Throughout the follow-up period, we did not observe any additional stroke or MI events. Additionally, there were no cases of in-stent restenosis, thrombosis, or reinterventions. Conclusion: Transcarotid artery revascularization can be performed in patients with restenotic carotid arteries with acceptable rates of ipsilateral stroke, MI, and death as demonstrated in this small multi-institutional series.

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