The influence of alendronate therapy on the quality of life in postmenopausal women with reduced bone mineral density

2018 ◽  
Vol 86 (4) ◽  
pp. 292
Author(s):  
Grażyna Bączyk ◽  
Dorota Formanowicz ◽  
Paweł Kleka ◽  
Włodzimierz Samborski
Keyword(s):  
Quality Of Life ◽  
Postmenopausal Women ◽  
Life Assessment ◽  
Mineral Density ◽  
Mean Values ◽  
Effect Of Treatment ◽  
The Mean ◽  
General Scale ◽  
Specific Scale

Introduction and objective: The aim of the study was to evaluate the effect of treatment on the quality of life (QoL) in postmenopausal women characterized by the reduced BMD.Material and methods: Postmenopausal women (n=102), mean age (65.09±5.6 years) were included in this study. The participants were divided into two groups, depending on the treatment or lack of treatment. For assessment of their QoL, QUALEFFO-41 scale and WHOQOL-100 scale were used.Results: Mean values of the QUALEFFO-41 scale of women who used alendronate were significantly lower than those found in subjects not treated with this drug in the following areas: pain (p=0.03), ADL (p=0.03), jobs around the house (p=0.01), mobility (p=0.01), health perception (p=0.03), emotional function (p= 0.007) and total QoL  (p=0.005). The mean values of the WHOQOL-100 scale almost did not differ significantly between both groups of studied patients. An exception was the level of independence, with mean values of women not receiving bisphosphonates being significantly higher than those of patients using bisphosphonates therapy (p=0.04).Conclusions. Quality of life assessment of women with osteoporosis and osteopenia using a specific scale and general scale can be a valuable clue in the planning of treatment, nursing care and psychological care.

scholarly journals Quality of Life in Postmenopausal Women and Its Correlation with Bone Mineral Density

2015 ◽  
Vol 26 (3) ◽  
pp. 58-64
Author(s):  
C Zonunsanga ◽  
Hmingthanmawii LNU ◽  
Minggam Pertin ◽  
Chongreilen Chiru ◽  
Romi Singh Nongmaithem ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
Significant Positive Association ◽  
The Mean

Abstract Aim To evaluate the quality of life in postmenopausal women and its correlation with bone mineral density. Study design Cross-sectional study. Duration of the study October 2012 to September 2014. Settings Physical Medicine and Rehabilitation Department, Regional Institute of Medical Sciences, Imphal. Study population Postmenopausal women who attended the department during the study period. Materials and Methods Quality of life was assessed using WHOQOL-BREF questionnaire, a validated brief version of the WHOQOL-100. Bone mineral density (BMD) in the lumbar spine, femoral neck and trochanter were measured using dual energy x-ray absorptiometry (DEXA) scan – GE Lunar model. Results A total of 125 patients were studied. The mean t-scores in lumbar spine, femoral neck and trochanter were -2.550 ± 1.209, -1.831 ± 0.921 and -1.621 ± 1.064 respectively. The mean BMD (g/cm2) in lumbar spine, femoral neck and trochanter were 0.867 ± 0.144, 0.789 ± 0.131 and 0.682 ± 0.139 respectively. The mean overall WHOQOL score was 57.68±10.07. There were statistically significant positive association of WHOQOL score with the BMDs in lumbar spine, femoral neck and trochanter (p < 0.05). Multivariate regression showed significant relation of overall WHOQOL score with BMD lumbar spine (b=0.229; R2=0.119), BMD femoral neck (b=0.285; R2=0.129), and BMD trochanter (b=0.245; R2=0.119). Conclusion BMDs in the lumbar spine, femoral neck and trochanter had a positive correlation with quality of life scores. BMD also had a good predictive value in determining the quality of life in postmenopausal women.

scholarly journals Quality of life assessment in chronic wound patients using the Wound-QoL and FLQA-Wk instruments

2020 ◽  
Vol 38 (3) ◽  
Author(s):  
Tatiele Naiara Vogt ◽  
Francisco José Koller ◽  
Pamella Naiana Dias Santos ◽  
Bruna Eloise Lenhani ◽  
Paulo Ricardo Bittencourt Guimarães ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Wounds ◽  
Treatment Plan ◽  
Life Assessment ◽  
University Hospital ◽  
Total Quality ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean

Objective. To evaluate changes in the quality of life of patients with chronic wounds. Methods. Quantitative research with a cross-sectional design performed with 100 patients with chronic wounds from a university hospital and a Basic Health Unit in southern Brazil. The mean values of the domains of the instruments Wound Quality of Life (Wound-QoL) and Freiburg Life Quality Assessment Wound were compared with sociodemographic variables of age, sex and education. Results. The average age of the participants was 60.98 years old; 41% had diabetic ulcers and 83% treated the wounds for more than 24 months. The total quality of life value was below the mean with 37.50/100 with (Wound-QoL) and 44.20/100 with (FLQA-Wk). The variables of gender, and educational level were not correlated with either of the two instruments used to assess the quality of life. The age variable was significantly correlated with the satisfaction item of the FLQA-Wk. Conclusion. The quality of life of patients with chronic wounds was considered poor. The age variable was correlated with the satisfaction domain, showing that the older the age, the lower the satisfaction. The use of instruments to evaluate the quality of life of patients with chronic wounds may help an effective treatment plan.

scholarly journals Quality of life in a sample of Brazilian adults using the generic SF-12 questionnaire

2018 ◽  
Vol 64 (3) ◽  
pp. 234-242 ◽  
Author(s):  
Alessandro Gonçalves Campolina ◽  
Rossana Veronica Mendoza Lopez ◽  
Elene Paltrinieri Nardi ◽  
Marcos Bosi Ferraz
Keyword(s):  
Quality Of Life ◽  
Skin Color ◽  
Short Form ◽  
Mean Value ◽  
Life Assessment ◽  
Future Research ◽  
Mean Values ◽  
Socio Demographic Factors ◽  
Assess Quality

Summary Objective: This study describes the summary scores of the Short Form-12 (SF-12) questionnaire, according to socio-demographic factors obtained in a probabilistic and representative sample of the Brazilian urban population. Method: Five thousand (5,000) individuals, over the age of 15, were assessed in 16 capital cities, in the five regions of the country. The selection of households was random. Face-to-face approach was applied in the household interviews. The SF-12 questionnaire was used to assess quality of life. Demographic and socioeconomic characteristics were also evaluated: gender, age, marital status, skin color, region of the country and use of the public health service. Results: The mean value (SD) of the SF-12 for the entire population was 49.3 (8.7) for the physical component (PCS-12) and 52.7 (9.7) for the mental component (MCS-12). Statistical differences were found for gender (PCS-12 and MCS-12), age (PCS-12) and working status (PCS-12 and MCS-12). Women, elderly, widowed and unemployed individuals, those with lower income and with complaints in the last seven days showed lower mean values (PCS-12 and MCS-12). Conclusion: From this point forward, we can provide the basis for comparisons with future research that use the SF-12 for quality of life assessment in Brazil. The Brazilian population has a lower degree of quality of life related do the physical component, and the SF-12 is a useful and discriminative instrument for assessing quality of life in different socio-demographic groups.

QOL assessment in head and neck cancer patients undergoing neoadjuvant chemotherapy and its impact on overall survival.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e17519-e17519
Author(s):  
Sachin Dhumal ◽  
Vijay Maruti Patil ◽  
Vanita Noronha ◽  
Amit Joshi ◽  
Atanu Bhattacharjee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Treatment Options ◽  
Life Assessment ◽  
The Mean

e17519 Background: NACT (neoadjuvant chemotherapy) is one of the treatment options in advanced head and neck cancer (H&N cancer); however there is limited quality of life data available in these patients. Methods: Between August 2013- April 2014, 90 technically unresectable H&N cancer patients who were underwent NACT at our centre were selected for this analysis. EORTC QLQ-C30 and HN35 version 3.0 was used for quality of life assessment at baseline and after 02 cycles of NACT. PFS and OS was estimated by Kaplan Meier method. The mean change in QOL at various domains was calculated with 95% CI. The relationship between change in QOL domain and OS was analysed. Results: The median age of the cohort was 45 years (Range 21-65 years). The predominant subsite was oral cavity, in 62 patients (68.9%).The median PFS and OS was 10.53 months (95%CI 8.1-13.0) and 20.8 months (95%CI 15.1-26.5). The mean scores for all domains of QOL are shown in table 1. Conclusions: NACT leads to improvement in QOL in patients treated with head and neck cancers and its has impact on OS.[Table: see text]

scholarly journals Health literacy and quality of life following rectal resections for cancer

2018 ◽  
Vol 5 (10) ◽  
pp. 3186
Author(s):  
Ba Thinh Nguyen ◽  
Toufic El-Khoury ◽  
Nimalan Pathmanathan ◽  
Peter Loder ◽  
Grahame Ctercteko
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Health Literacy ◽  
Rectal Cancer Patient ◽  
Significant Proportion ◽  
Life Assessment ◽  
Cross Sectional ◽  
Low Health Literacy ◽  
The Mean

Background: Health literacy can be a stronger predictor of an individual’s health status than income, employment status, education level, and racial or ethnic group. The prevalence and impact of low health literacy in the rectal cancer patient population has received little attention. This study is a cross-sectional population survey to determine if there is a relationship between health literacy and quality of life in rectal cancer patients.Methods: All rectal cancer patients having a clinical encounter with the Colorectal Unit at Westmead Hospital will be invited to participate in the study. Two validated health literacy screens (REALM-SF and NVS) were administered along with the EORTC QLQ-C30 quality of life assessment. The association between health literacy and quality of life will be examined using Spearman regression.Results: 92 patients were recruited between March 2015 and July 2016. A significant proportion of our patients were found to have low health literacy (29.3 percent and 54.5 percent as measured by the REALM-SF and NVS, respectively). The mean QLQ-C30 summary score was 71.5 and the mean global health score was 69.4 (SD 23.3). There appeared to be no statistically significant correlation between health literacy and quality of life in our study. There was a moderately positive correlation between the NVS and REALM-SF (rho = 0.36, P <0.001).Conclusions: A significant proportion of our patients that have had rectal resections for cancer have low health literacy. We have not been able to demonstrate an obvious association between health literacy and quality of life in the present study.

scholarly journals Lengthening Temporalis Myoplasty: Objective Outcomes and Site-Specific Quality-of-Life Assessment

2017 ◽  
Vol 157 (6) ◽  
pp. 966-972 ◽  
Author(s):  
Davide Thomas Panciera ◽  
Claudio Sampieri ◽  
Alberto Deganello ◽  
Giovanni Danesi
Keyword(s):  
Quality Of Life ◽  
Demographic Data ◽  
Case Series ◽  
Life Assessment ◽  
Life Outcomes ◽  
A Value ◽  
The Mean ◽  
Objective Outcomes ◽  
Oral Commissure

Objective Evaluate outcomes of the lengthening temporalis myoplasty in facial reanimations. Study Design Case series with planned data collection. Setting Ospedali Riuniti, Bergamo, and AOUC Careggi, Florence, Italy. Subjects and Methods From 2011 to 2016, 11 patients underwent lengthening temporalis myoplasty; demographic data were collected for each. Pre- and postoperative photographs and videos were recorded and used to measure the smile angle and the excursion of the oral commissure, according to the SMILE system (Scaled Measurements of Improvement in Lip Excursion). All patients were tested with the Facial Disability Index, and they also completed a questionnaire about the adherence to physiotherapy indications. Results All patients demonstrated a significant improvement in functional parameters and in quality of life. On the reanimated side, the mean z-line and a-value, measured when smiling, significantly improved in all patients: from 22.6 mm (95% CI, 20.23-25.05) before surgery to 30.9 mm (95% CI, 27.82-33.99) after surgery ( P < .001) and from 100.5° (95% CI, 93.96°-107.13°) to 111.6° (95% CI, 105.63°-117.64°; P < .001), respectively. The mean postoperative dynamic gain, passing from rest to a full smile at the reanimated side, was 3.1 mm (95% CI, 1.30-4.88) for the z-line and 3.3° (95% CI, 1.26°-5.29°) for the a-value. The Facial Disability Index score increased from a preoperative mean of 33.4 points (95% CI, 28.25-38.66) to 49.9 points (95% CI, 47.21-52.60) postoperatively ( P < .001). Conclusions The lengthening temporalis myoplasty can be successfully used for smile reanimation, with satisfying functional and quality-of-life outcomes.

scholarly journals The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial

2021 ◽  
Author(s):  
Mahboobeh Shirazi ◽  
Mohamad Naser Jalalian ◽  
Masoumeh Abed ◽  
Marjan Ghaemi
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Sleep Disturbance ◽  
Postmenopausal Women ◽  
Melissa Officinalis ◽  
Foeniculum Vulgare ◽  
Double Blind ◽  
Menopausal Women ◽  
The Mean

Abstract Objective The present study aimed to assess the effect of Melissa Officinalis L. (a combination of lemon balm with fennel fruit extract) compared with citalopram and placebo on the quality of life of postmenopausal women with sleep disturbance. Methods The present study is a randomized, double-blind, placebo clinical trial among 60 postmenopausal women with sleep disturbance who were referred to a university hospital from 2017 to 2019. The participants were randomized to receive M. Officinalis L. (500 mg daily), citalopram (30 mg) or placebo once daily for 8 weeks. The Menopause-Specific Quality of Life (MENQOL) questionnaire was self-completed by each participant at baseline and after 8 weeks of the intervention and was compared between groups. Results The mean for all MENQOL domain scores were significantly improved in the M. Officinalis L. group compared with citalopram and placebo (p < 0.001). The mean ± standard deviation (SD) after 8 weeks in the M. Officinalis L., citalopram and placebo groups was 2.2 ± 0.84 versus 0.56 ± 0.58 versus 0.36 ± 0.55 in the vasomotor (p < 0.001), 1.02 ± 0.6 versus 0.28 ± 0.2 versus 0.17 ± 0.1 in the psychomotor-social (p < 0.001), 0.76 ± 0.4 versus 0.25 ± 0.1 versus 0.11 ± 0.1 in the physical and 2.3 ± 1.0 versus 0.35 ± 0.5 versus 0.41 ± 0.5 in the sexual domain, respectively. Conclusions The results revealed that M. Officinalis L. may be recommended for improving the quality of life of menopausal women with sleep disturbance. Trial registration The present study was registered by the name “Comparison of the efficacy of citalopram and compound of Asperugo procumbens and foeniculum vulgare in treatment of menopausal disorders” with the code IRCT2013072714174N1 in the Iranian Registry of Clinical Trials (IRCT).

scholarly journals Quality of Life among Iranian Postmenopausal Women: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 9 ◽  
pp. 1649
Author(s):  
Khadijeh Sharifi ◽  
Zahra Tagharrobi ◽  
Zahra Sooki
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Postmenopausal Women ◽  
Meta Analysis ◽  
Scientific Information ◽  
Educational Interventions ◽  
Cross Sectional ◽  
Sexual Symptoms ◽  
The Mean

Menopause can cause mental, physical, vasomotor, and sexual symptoms and problems, which negatively affect the quality of life (QOL). The aim of this study was to systematically evaluate QOL among Iranian postmenopausal women. This systematic review was conducted on cross-sectional studies that were published between 2000 and 2018. An online search to find studies published in English or Persian was conducted in the databases of Web of Science, PubMed, ScienceDirect, Scopus, Google Scholar, Scientific Information Database, Magiran, and IranMedex. Search key terms were “quality of life”, “menopause”, and “Iran”. Fourteen studies were eligible for this study. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist was used for quality appraisal. The mean and standard deviation of QOL and its domains were extracted from the selected studies. Study data were analyzed using the Review Manager (v. 5.0) and the STATA (v. 12.0) software. The mean of total QOL among 3413 postmenopausal women was 57.89±12.8 (in the possible range of 0–174). The means of its vasomotor, psychosocial, physical, and sexual domains were 7.86±2.14, 19.43±2.05, 40.58±3.33, and 6.71±1.77, respectively. The QOL among Iranian postmenopausal women is nearly higher than the moderate level. The lowest and the highest levels of QOL are related to the physical and sexual domains, respectively. Health authorities need to develop educational interventions to promote postmenopausal women’s QOL, particularly in the physical domain. [GMJ.2020;9:e1649]

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