scholarly journals THE CORRELATION BETWEEN EPICARDIAL FAT THICKNESS BASED ON MULTI SLICE COMPUTED-TOMOGRAPHY SCAN THORAX WITH WAIST CIRCUMFERENCE AND BODY MASS INDEX ON DYSLIPIDEMIA NON-DIABETES MELLITUS SUBJECT

2018 ◽  
Vol 3 (1) ◽  
pp. 8
Author(s):  
Yenny Wendy ◽  
Mirna Muis

Introduction : Epicardial fat is visceral fat that plays a role in cardiovascular disease. Dyslipidemia non-diabetes mellitus can be found in both obese and non-obese patients. Measurement of waist circumference and BMI can assess central and peripheral obesity. The study aims to finding out the correlation between epicardial fat thickness based on MSCT scan Thorax with waist circumference and BMI on dyslipidemia non-diabetes mellitus subject. Method: There were 57 research samples of 28 to 70 years old who had dysfunction lipid profile. The most samples were found in the age group of 45-64 years with epicardial fat ranges from 2.80 to 10.80 mm and mean of 6.37 mm. Data were analysed by Mann-Whitney and Spearman correlation test. Result: There was a significant correlation between waist circumference and epicardial fat (r = 0.286, p = 0,031). There was no difference in mean of epicardial fat thickness by sex. There was no correlation between sex, and BMI with epicardial fat. Conclusion: There is a correlation between waist circumference and epicardial fat that may be affected by several factors in patients with dyslipidemia non-diabetes mellitus.

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Mustafa Cetin ◽  
Musa Cakici ◽  
Mustafa Polat ◽  
Arif Suner ◽  
Cemil Zencir ◽  
...  

Aims.The aim of this study was to investigate the relationship of echocardiographic epicardial fat thickness (EFT) with carotid intima-media thickness (CIMT), in patients with type 2 diabetes mellitus (T2DM).Methods and Results.A total of 139 patients with T2DM (mean age 54.3 ± 9.2 and 49.6% male) and 40 age and sex-matched control subjects were evaluated. Echocardiographic EFT and ultrasonographic CIMT were measured in all subjects. Patients with T2DM had significantly increased EFT and CIMT than those of the controls (6.0 ± 1.5 mm versus 4.42 ± 1.0 mm,P<0.001and 0.76 ± 0.17 mm versus 0.57 ± 0.14 mm,P<0.001, resp.). EFT was correlated with CIMT, waist circumference, BMI, age, duration of T2DM, HbA1c in the type 2 diabetic patients. Linear regression analysis showed that CIMT (β=3.52,t=3.72,P<0.001) and waist circumference (β=0.36,t=2.26,P=0.03) were found to be independent predictors of EFT. A cutoff high risk EFT value of 6.3 mm showed a sensitivity and specificity of 72.5% and 71.7%, respectively, for the prediction of subclinical atherosclerosis.Conclusion.We found that echocardiographic EFT was significantly higher in patients with T2DM. Our study also showed that EFT was strongly correlated with waist circumference and CIMT as being independent of sex.


Author(s):  
Graurav Runwal ◽  
Saurabh Daseda

Method: FBS/PPBS done by GOD POD method IN Vitros “S”, FS machine. HBA1C Done by HPLC plus ion exchange resin. Lipid profile after overnight fasting of 12 hours blood collected in the morning about 5 ml and the serum centrifuged and kept for analysis. Serum cholesterol estimation: The CHOD-PAP method, enzymatic colorimetric test was used in Vitros “S”, FS machine. Result: After applying Levene’s test for equality of variance, t test between mean of epicardial fat thickness and visceral fat thickness between obese and non-obese groups, shows statistically significant (p=<0.05) association. Obese patients(11.88+1.40) had significantly more epicardial fat thickness as compared to non-obese type 2 diabetes patients (10.19+1.37), t(148) = -7.39, (p=<0.05). Obese patients (58.85+10.89) had significantly more visceral fat thickness as compared to non-obese type 2 diabetes patients (46.23+9.79), t (148) = -7.34, (p= <0.05). Conclusion: Diabetes mellitus (DM) refers to a group of common metabolic disorders lead to phenotype of hyperglycemia and caused by a complex interaction of genetics and environmental factors. We concluded that EFT and VAT were significantly correlated among obese diabetics as compare to non-obese diabetic suggesting, Obesity is an independent risk factor for visceral adipose tissue deposition both in abdomen as well as in epicardial surface. Keywords: Epicardial, Fat Thickness, Abdominal, DM, & Obese.


2014 ◽  
Vol 6 (1) ◽  
pp. 120 ◽  
Author(s):  
Gökay Nar ◽  
Sinan Inci ◽  
Gökhan Aksan ◽  
Oguz Unal ◽  
Rukiye Nar ◽  
...  

2015 ◽  
Vol 32 (12) ◽  
pp. 1745-1753 ◽  
Author(s):  
Abdullah Nabi Aslan ◽  
Telat Keleş ◽  
Hüseyin Ayhan ◽  
Hacı Ahmet Kasapkara ◽  
Murat Akçay ◽  
...  

2013 ◽  
Vol 167 (5) ◽  
pp. 2244-2249 ◽  
Author(s):  
Stefania Mariani ◽  
Daniela Fiore ◽  
Giuseppe Barbaro ◽  
Sabrina Basciani ◽  
Maurizio Saponara ◽  
...  

2021 ◽  
Vol 26 (3) ◽  
pp. 4343
Author(s):  
V. A. Ionin ◽  
E. I. Baraschkova ◽  
E. L. Zaslavskaya ◽  
S. E. Nifontov ◽  
E. A. Bazhenova ◽  
...  

Aim. To determine the blood level of inflammatory markers, parameters characterizing obesity and cardiac remodeling in patients with atrial fibrillation (AF) in combination with metabolic syndrome (MS).Material and methods. This single-stage case-control study included 677 subjects aged 35 to 65 years: patients with MS (n=407), of which 128 patients with AF; comparison group — patients with AF without MS (n=75); control group — practically healthy subjects without cardiovascular diseases and metabolic disorders (n=195).Results. It was found that the blood concentration of circulating pro-inflammatory biomarkers in patients with AF and MS is higher than in patients with AF without MS: C-reactive protein (CRP) (4,43 (2,68-4,98) and 2,33 (1,08-4,7) mg/L, p<0,0001), interleukin-6 (IL-6) (2,5 (1,28-5,13) and 1,27 (0,68-2,7) pg/ml, p<0,0001) and tumor necrosis factor-α (TNF-α) (5,18 (2,63-7,32) and 3,42 (2,115,48) pg/ml, p<0,0001). The serum CRP concentration positively correlates with left (ρ=0,451, p<0,0001) and right atrial (ρ=0,412, p<0,000) volumes, as well as with the waist circumference (ρ=0,503, p<0,001) and epicardial fat thickness (ρ=0,550, p<0,001). Plasma IL-6 and serum TNF-α levels correlated to a lesser extent with parameters characterizing atrial remodeling, but had a strong positive relationship with epicardial fat thickness. According to multivariate analysis, it was found that an increase in the epicardial fat thickness had a greater effect on an increase in blood concentration of CRP, IL-6 and TNF-α, in contrast to other parameters characterizing obesity, such as body mass index and waist circumference.Conclusion. An increase in the blood concentration of proinflammatory biomarkers CRP, IL-6, and TNF-α is associated with cardiac remodeling and epicardial fat thickness in patients with MS and probably has a pathogenetic role in increasing the AF risk in this cohort of patients.


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