Effect of preoperative ureteral stent on urinary tract infection and the outcomes of flexible ureteroscopic lithotripsy
Abstract Background: To investigate the effect of preoperative ureteral stent on preoperative antibiotic application and explored whether these stent aggravated the patient's urinary tract infection and increased the risk of postoperative urosepsis.Method: All patients treated for urinary stones with flexible ureteroscopy interventions between January 2018 to September 2019 at our institution was enrolled to this study. The patient's baseline data, operative time, total length of hospital stay, duration of antibiotic use before surgery, days from admission to surgery, and perioperative laboratory results were recorded. The chi-square test was used to analyze categorical variables, and the independent sample Student's t test was used for numerical variables.Result: A total of 469 patients were included in the analysis eventually. The positive rate of urine culture in the stent group was higher. The white blood cell (WBC) level within 1 hour after surgery in the stent group was significantly lower. The urinary leukocyte counts (ULC) at admission in patients in the stent group were significantly higher, as well as for the preoperative ULC. The serum albumin (ALB) level at admission and 1 hour after surgery of patients in the stent group was significantly lower than that in the non-stent group at admission. The total length of hospital stay of stent group was prolonged. The probability of postoperative urosepsis had no statistical difference.Conclusion: The patient's urinary tract infections were aggravated by preoperative stent. Although the stent group had a higher probability of postoperative sepsis in 48 hours, yet there was no significant differences in the incidence of postoperative urosepsis between the two groups.