scholarly journals A Cross-Sectional Study Of The Association Between Skin Tags And Vascular Risk Factors In Patients With Severe And Complicated Obesity

2020 ◽  
Author(s):  
Clarissa Ern Hui Fang ◽  
Catherine Crowe ◽  
Annette Murphy ◽  
Martin O’Donnell ◽  
Francis Martin Finucane

Abstract Objective: We sought to determine whether the presence of cervical or axillary skin tags was associated with an adverse cardiovascular risk profile in Irish adults with severe obesity. Results: We conducted a cross-sectional study of patients attending our regional bariatric centre. Of 167 patients, 100 (31% male, 37% with type 2 diabetes, 36% on lipid lowering therapy, 41% on antihypertensive therapy) agreed to participate. 85 patients had cervical or axillary tags while 15 had none. Those with any skin tags had higher systolic blood pressure (138.0±16.0 versus 125.1±8.3 mmHg, p=0.003) and higher glycated haemoglobin (HbA1c) (46.5±13.2 versus 36.8±3.5 mmol/mol, p=0.017). 94.6% of patients with diabetes, compared to 79.4% of those without diabetes had skin tags (p=0.039). 45.8% of patients with skin tags compared to 13.3% with no tags were on antihypertensive therapy (p=0.018). Skin tags were not associated with any differences in lipid profiles. In Irish adults with severe obesity, skin tags are associated with higher systolic blood pressure and HbA1c and a higher prevalence of diabetes and hypertension, consistent with increased vascular risk, though differences in lipid profiles were not found.

2020 ◽  
Author(s):  
Clarissa Ern Hui Fang ◽  
Catherine Crowe ◽  
Annette Murphy ◽  
Martin O’Donnell ◽  
Francis Martin Finucane

Abstract Objective: Skin tags are associated with an insulin resistant phenotype but studies in White Europeans with morbid obesity are lacking. We sought to determine whether the presence of cervical or axillary skin tags was associated with increased cardiovascular risk in Irish adults with morbid obesity. We conducted a cross-sectional study of patients attending our Irish regional bariatric centre with a BMI ≥40 kgm-2(or ≥35 kgm-2 with co-morbidities). We compared anthropometric and metabolic characteristics in those with versus without skin tags. Results: Of 164 patients, 100(31 male, 37 with type 2 diabetes, 36 on lipid lowering therapy, 41 on antihypertensive therapy) participated. Mean age was 53.7±11.3 (range 31.1-80)years. Cervical or axillary tags were present in 85 patients. Those with tags had higher systolic blood pressure 138.0±16.0 versus 125.1±8.3 mmHg, p=0.003) and HbA1c(46.5±13.2 versus 36.8±3.5 mmol/mol, p=0.017). Tags were present in 94.6% of patients with diabetes, compared to 79.4% of those without diabetes(p=0.039). Antihypertensive therapy was used by 45.8% of patients with skin tags compared to 13.3% without tags (p=0.018). In bariatric clinic attenders skin tags were associated with higher SBP and HbA1c and a higher prevalence of diabetes and hypertension, consistent with increased vascular risk, but lipid profiles were similar.


2017 ◽  
Vol 6 (4) ◽  
pp. 313
Author(s):  
Mega Lucyta Sari ◽  
Enny Probosari ◽  
Hartanti Sandi Wijayanti

Background: Hypertension is one of the major risk factors for cardiovascular disease. Decreased intake of omega-3 and increased intake of omega-6 can increase the risk of hypertension. Hypertension cases in Indonesia are highest in women especially aged 30 - 50 years. This study aimed to determine correlation of omega-3 and omega-6 intake with blood pressure in women aged 30-50 years.Method : This was an observational research with cross-sectional study design. Fifty four subjects were selecting using consecutive sampling. Intakes were assessed by food recall 2x24 hours. Blood pressure levels were measured by Sphygmomanometer. Data were analyzed by Chi Square and Fisher Exact.Result : Systolic and diastolic blood pressure mean were 115.92 ± 14.5 mmHg and 75 ± 7.45 mmHg, while omega-3 and omega-6 mean were of 3. 1.03 ± 0.52 g and 14.17 ± 5 , 8 g. More than one third of the subjects (37.9%) with pre-hypertension/hypertension had omega-3 intake less than 1.1 g and 52.7% of them had omega-6 intake less than 12 g.There was correlation of omega-6 intake with systolic blood pressure (p <0.05) but there were no correlation between omega-3 intake with systolic blood pressure, omega-3 and omega-6 intake with diastolic blood pressure (p >0,05). Conclusion: There was correlation of omega-6 intake with systolic blood pressure, there were no correlation between omega-3 intake with systolic blood pressure, omega-3 and omega-6 intake with diastolic blood pressure


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Thirunavukarasu Kumanan ◽  
Vathulan Sujanitha ◽  
Nadarajah Rajeshkannan ◽  
Balasingam Nisahan

Abstract Objective This small scale cross-sectional study was done to identify the common systolic blood pressure pattern (dipping or non-dipping) among type 2 diabetic men with coexisting hypertension and erectile dysfunction(ED). A recent study in the same setting showed that prevalence of ED was high among diabetic men and co-existing hypertension was identified as an independent risk factor. There was a postulation about an association between ED and non-dipping nocturnal blood pressure pattern. So ambulatory blood pressure measurements (ABPM) was obtained for participants to test this prediction. Data was analysed using SPSS 25 Version. Results Among 29 participants who underwent ABPM, 21 showed non-dipping pattern of nocturnal systolic blood pressure (72.4%; CI 54.3–86.3). Mean SBP of participants was 125.55 +_14.1 and Mean DBP was 81.5 + _12.82. There was no statistical difference observed in mean SBP and DBP between patients with dipping nocturnal SBP and non-dipping pattern (P > 0.05). Variability of SBP was high among the participants (Mean SD-11.96 +/_2.74) and DBP also showed relatively high variability (SD-9.28 +/_2.9). Mean dipping percentage of the SBP during sleep was 5.54 +/_6.66. A significant difference in heart rate (HR) between patients with non-dipping and dipping pattern was noted (P-0.034).


2018 ◽  
Vol 19 (1&2) ◽  
pp. 28-30
Author(s):  
Nadya Gratia Juliawan ◽  
Listya Tresnanti Mirtha ◽  
Muchtarudin Mansyur ◽  
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2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Akdri Andi ◽  
Afriwardi Afriwardi ◽  
Detty Iryani

AbstrakPada olahraga tertentu seperti futsal,  tekanan darah dapat naik menjadi 150-200 mmHg. Sebuah penelitian menyatakan  60 kematian mendadak pasca olahraga, 58 diantaranya disebabkan oleh kelainan kardiovaskuler. Tujuan penelitian ini adalah untuk mengetahui gambaran perubahan tekanan darah pasca olahraga futsal pada mahasiswa Fakultas Kedokteran Universitas Andalas. Rancangan penelitian yang digunakan adalah deskriptif observasional dengan menggunakan desain cross-sectional study. Subjek yang digunakan adalah 30 orang mahasiswa Fakultas Kedokteran Universitas Andalas yang memenuhi kriteria inklusi dan eklusi pada April 2014. Olahraga futsal dilakukan 30 menit lalu dilakukan pengukuran tekanan darah sesaat, 15, 30 dan 60 menit dengan menggunakan sphygmomanometer air raksa dan stetoskop. Hasil penelitian didapatkan peningkatan tekanan darah sistolik sesaat setelah olahraga futsal pada semua sampel dengan peningkatan sebesar 20 mmHg pada 18 orang (60%) dan 25 orang (83,8%) tidak mengalami perubahan tekanan darah diastolik. Pada 15 menit setelah olahraga futsal, 18 orang (60%) terjadi penurunan tekanan darah sistolik sebesar 20 mmHg dan 26 orang (86,67%) tidak mengalami perubahan tekanan darah diastolik. Pada 30 menit setelah olahraga, 4 orang (13,3%) mengalami penurunan tekanan darah sistolik. Satu jam setelah olahraga, semua subjek telah mencapai tekanan darah awal.Kata kuncl: tekanan darah, olahraga futsal sesaat, 15 menit, 30 menit, satu jam AbstractIn certain exercise such as futsal, blood pressure can raise around 150-200 mmHg. A study has identified 60 sudden deaths after sports and 58 were caused by cardiovascular disorders. The objective of this study was to describe changes in blood pressure after futsal exercise in students of Medical Faculty of Andalas University. The design is descriptive observational using a cross-sectional study. The 30 subjects were taken base on inclusion and exclusion criteria. This study was conducted on April 2014. Subject played futsal for 30 minutes, then the blood pressure was measured right after doing futsal then 15, 30 and 60 minutes later with a sphygmomanometer and stethoscope. This study found an increase in systolic blood pressure shortly after  futsal in all subjects with an increase of 20 mmHg in 18 people (60%) and 25 people (83.8%) had no change in diastolic blood pressure. Fifteen minutes after doing futsal, 18 people (60%) had 20 mmHg decrease in systolic blood pressure and 26 (86.67%) had no change in diastolic blood pressure. Thirty minutes after doing futsal, 4 (13.3%) experienced a decrease in systolic blood pressure and 100%  returned to the initial blood pressure. One hour after exercise, all of subjects  reached the initial blood pressure again.Keywords: blood pressure, right after doing futsal, 15 minutes, 30 minutes, one hour


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