scholarly journals The Prevalence and Treatment Options of Melasma as Well as its Association with Quality of Life in Darker Skin Types: A Scoping Review Protocol

2021 ◽  
Author(s):  
Nomakhosi Mpofana ◽  
Buyisile Chibi ◽  
Nceba Gqaleni ◽  
Ahmed Hussain Mohammed ◽  
Avenal Jane Finlayson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Scoping Review ◽  
Research Question ◽  
Treatment Options ◽  
Relevant Literature ◽  
Treatment Modalities ◽  
Review Protocol ◽  
And Gender ◽  
Darker Skin Types

Abstract BackgroundMelasma is one of the most encountered dermatoses in dermatology and skin care clinics. It is a challenging chronic, recurrent condition associated with hyperpigmentation. Its etiology is poorly understood. Melasma affects all races and gender but is more prevalent in women with darker skin types. Being a facial lesion, melasma has a severe impact on quality of life due to its disfigurement. While many modalities of treatment for melasma exists, unfortunately, effectiveness and safety remain a huge concern. Treatment modalities are variable and often unsatisfactory. The objective of this scoping review is to systemically map available evidence from literature regarding melasma, garner insight as to how melasma affects the quality of life and begin to investigate and gain understanding on effectiveness of different treatments used for melasma.MethodsA scoping review guided by Arksey and O’Malley’s framework, the enhancements and recommendations of Levac, Colquhoun and O’Brien, Daudt and associates and the 2015 Johanna Briggs Institute’s guidelines will be conducted. Systematic electronic searches of databases and search engines such as, Scopus, PubMed, CINAHL Complete, Cochrane, Science Direct, and Web of Science will be conducted to attain published peer-reviewed articles of all study designs excluding reviews. All literature that meets the inclusion criteria, research question and sub-question will be included in this review. All the retrieved literature will be exported to an Endnote X20 library. Quality appraisal of the included articles will be conducted using the mixed methods appraisal tool (MMAT) 2018 version.DiscussionWe anticipate mapping relevant literature on the prevalence of melasma, investigating the effectiveness of treatment options of melasma as well as evaluating its association with quality of life in darker skin types. This study is likely to reveal research gaps, which could guide future implementation research on melasma treatment interventions.Protocol registration: This protocol has been registered apriori with OSF and is accessible on this link: https://osf.io/ru3jc/

scholarly journals Psychosocial and quality of life impact of scars in the surgical, traumatic and burn populations: a scoping review protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e021289
Author(s):  
Natalia Ziolkowski ◽  
Simon C Kitto ◽  
Dahn Jeong ◽  
Jennifer Zuccaro ◽  
Thomasin Adams-Webber ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Scoping Review ◽  
Research Question ◽  
Grey Literature ◽  
Psychosocial Health ◽  
Emotional Disturbances ◽  
Study Selection ◽  
Life Impact ◽  
Methodological Considerations

IntroductionDespite the fact that millions of scars affect individuals annually, little is known about their psychosocial impact and overall quality of life (QOL) on individuals. Scars from multiple aetiologies may cause psychiatric and emotional disturbances, can limit physical functioning and increase costs to the healthcare system. The purpose of this protocol is to describe the methodological considerations that will guide the completion of a scoping review that will summarise the extent, range and nature of psychosocial health outcomes and QOL of scars of all aetiologies.Methods and analysisA modified Arksey and O’Malley (2005) framework will be completed, namely having ongoing consultation between experts from the beginning of the process, then (1) identifying the research question/s, (2) identifying the relevant studies from electronic databases and grey literature, with (3) study selection and (4) charting of data by two independent coders, and (5) collating, summarising and reporting data. Experts will include a health information specialist (TAW), scar expert (JSF), scoping review consultant (SCK), as well as at least two independent coders (NZ, AM).Ethics and disseminationEthics approval will not be sought for this scoping review. We plan to disseminate this research through publications, presentations and meetings with relevant stakeholders.

scholarly journals Music Therapy and Dance as Gait Rehabilitation in Patients With Parkinson Disease: A Review of Evidence

2018 ◽  
Vol 32 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Ana Paula S. Pereira ◽  
Victor Marinho ◽  
Daya Gupta ◽  
Francisco Magalhães ◽  
Carla Ayres ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Music Therapy ◽  
Parkinson Disease ◽  
Cognitive Abilities ◽  
Treatment Options ◽  
Music Performance ◽  
Well Being ◽  
The Elderly ◽  
Treatment Modalities

Parkinson disease causes several changes in gait, such as postural stability, which consequently induces fall risk factors and loss of quality of life. Alternative forms of treatment through rhythmic and dance stimuli have been used to minimize the Parkinson disease effects, which have been shown to be effective in improving gait and providing social well-being and quality of life in the patient. Aim: This review aims to demonstrate the efficiency of music and dance for gait improvement and symptom alleviation in Parkinson disease. Methodology: Studies that analyzed sound stimuli and dance in gait improvement in Parkinson disease were searched through PubMed, Scopus, Doaj, MEDLINE, and ScienceDirect databases from November 2017 to April 2018 and repeated in September 2018. Results and Discussion: Forty-five studies met the inclusion criteria to synthesize the findings on dance and music performance as a treatment for classical symptoms of Parkinson disease. Five reviews and 40 experimental papers have shown that rhythmic stimulation and dance provide the motor, cognitive, and quality of life benefits for participants with Parkinson disease. Thus, sound stimuli and dance offer satisfactory effects for gait, improving cognitive abilities such as motor control and adjustment and spatial memory. In addition, these new treatment modalities stimulate the elderly population to practice physical exercise, generating well-being and helping self-esteem. Conclusion: Dance and music therapy interventions are noninvasive, simple treatment options, which promote gait and cognition.

Treatment of painful diabetic peripheral neuropathy

2015 ◽  
Vol 39 (1) ◽  
pp. 17-28 ◽  
Author(s):  
Casandra J Rosenberg ◽  
James C Watson
Keyword(s):  
Quality Of Life ◽  
Peripheral Neuropathy ◽  
Side Effects ◽  
Diabetic Peripheral Neuropathy ◽  
Pain Control ◽  
Treatment Options ◽  
Mechanisms Of Action ◽  
Treatment Modalities ◽  
Painful Diabetic Peripheral Neuropathy

Background: Painful diabetic peripheral neuropathy impairs quality of life and can be difficult to treat. Objective: To discuss current treatment recommendations for painful diabetic peripheral neuropathy. Study design: Literature review. Methods: Systematic review of the literature discussing treatment of painful diabetic peripheral neuropathy. Existing treatment guidelines were studied and compared. Results: Painful diabetic peripheral neuropathy occurs in about one in six people with diabetes. This condition impairs quality of life and increases healthcare costs. Treatment recommendations exist, but individual patient therapy can require a trial-and-error approach. Many treatment options have adjuvant benefits or side effects which should be considered prior to initiating therapy. Often, a combination of treatment modalities with various mechanisms of action is required for adequate pain control. Adequate medication titration and a reasonable trial period should be allowed. Conclusion: The treatment of painful diabetic peripheral neuropathy can be challenging, but effective management can improve patient’s quality of life. Clinical relevance Painful diabetic peripheral neuropathy impairs quality of life and can be difficult to treat. Many treatment options have adjuvant benefits or side effects which should be considered prior to initiating therapy. Often, a combination of treatment modalities with various mechanisms of action is required for adequate pain control.

scholarly journals Development of a Systematic Review Protocol and a Scoping Review of Ultrasound-Induced Immune Effects in Peripheral Tumors

2021 ◽  
Author(s):  
Anne Rix ◽  
Renée Girbig ◽  
Céline Porte ◽  
Wiltrud Lederle ◽  
Cathalijn Leenaars ◽  
...  
Keyword(s):  
Systematic Review ◽  
Scoping Review ◽  
Meta Analysis ◽  
Research Question ◽  
Relevant Literature ◽  
Selection Strategy ◽  
Tumor Type ◽  
Systematic Review Protocol ◽  
Study Characteristics ◽  
Review Protocol

Abstract Purpose Publication numbers reporting that ultrasound can stimulate immune reactions in tumors steadily increase. However, the presented data are partially conflicting, and mechanisms are difficult to identify from single publications. These shortcomings can be addressed by a systematic review and meta-analysis of current literature. As a first step, we here present the methodology and protocol for a systematic review to answer the following research question: Does ultrasound alter the immune reaction of peripheral solid tumors in humans and animals compared to control conditions without ultrasound? Procedures We designed a protocol to perform a systematic review and meta-analysis. The suitability of the protocol to detect and sort relevant literature was tested using a subset of publications. We extracted study characteristics, ultrasound parameters, and study outcomes to pre-evaluate the differences between publications and present the data as a scoping review. Results From 6532 publications detected by our preliminary literature search, 320 were selected for testing our systematic review protocol. Of the latter, 15 publications were eligible for data extraction. There, we found large differences between study characteristics (e.g., tumor type, age) and ultrasound settings (e.g., wavelength 0.5–9.5 MHz, acoustic pressure 0.0001–15,000 W/cm2). Finally, study outcomes included reports on cells of the innate (e.g., dendritic cells, macrophages) and adaptive immune system (e.g., CD8-/CD4-positive T cells). Conclusion We designed a protocol to identify relevant literature and perform a systematic review and meta-analysis. The differences between extracted features between publications show the necessity for a comprehensive search and selection strategy in the systematic review to get a complete overview of the literature. Meta-analyses of the extracted outcomes can then enable evidence-based conclusions.

scholarly journals Rare cases of appendicitis presented in KIMS Amalapuram, India: a clinical study

2017 ◽  
Vol 4 (11) ◽  
pp. 3779
Author(s):  
M. Uday Kiran ◽  
B. Rakesh ◽  
L. Hari Prasad Rao ◽  
P. Avinash ◽  
D. Amrita Manjusha ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Appendicitis ◽  
Carcinoid Tumour ◽  
Treatment Options ◽  
Treatment Modalities ◽  
Current Standard ◽  
Rare Presentation ◽  
Omental Patch ◽  
Perforated Appendix

RIF pain is a hall mark of acute appendicitis until proven otherwise decision making in a case of acute appendicitis may be difficult for junior surgeons hence we aimed at analysis in RIF pain. Out of 120 cases we found 3 rare entities they are PMP, CT of appendix and perforated appendix in LIF. Pseudomyxomaperinei and carcinoid tumour are rare presentations. Despite the current standard of treatment modalities as extensive surgical resection combined with chemotherapy, PMP and CT frequently recurs with treatment options being limited at recurrence and with severe impact on quality of life. Perforated appendix in LIF is also a rare presentation which needs appendicectomy, perforation closer with omental patch.

scholarly journals Non-pharmacological interventions for improving quality of life of long-term care residents with dementia: a scoping review protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e032661
Author(s):  
Abimbola A Akintola ◽  
Wilco P Achterberg ◽  
Monique A A Caljouw
Keyword(s):  
Quality Of Life ◽  
Scoping Review ◽  
Long Term Care ◽  
Pharmacological Interventions ◽  
Term Care ◽  
People With Dementia ◽  
Scoping Reviews ◽  
Review Protocol

IntroductionEvidence concerning the effectiveness of non-pharmacological interventions that are applied to people with dementia living in long-term care facilities is inconsistent. The purpose of this protocol is to describe the methodological considerations that will guide the completion of a scoping review that will inventorise and assess the effectiveness of the various non-pharmacological interventions that are documented in literature for improving quality of life of people with dementia living in long-term care.Methods and analysisThis scoping review will combine the methodology outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews and Guidance for conducting systematic scoping reviews by Peterset al. PubMed; MEDLINE; CINAHL; Embase; Cochrane Database of Systematic Reviews; Cochrane Central Register of Controlled Trials; Emcare; Sociological Abstracts and PsycINFO databases will be searched. Grey literature databases will also be explored. A two-stage screening process consisting of a title and abstract scan and a full-text review will be used to determine the eligibility of studies. Studies, irrespective of design, will be included that quantitatively assess quality of life of long-term care residents who receive non-pharmacological interventions for dementia. A pair of reviewers will independently assess all articles for eligibility, and all eligible articles will be abstracted and charted using a standardised form. The extracted data will undergo a ‘narrative review’ or a descriptive analysis of the contextual or process-oriented data and quantitative analysis reflecting the objectives of this scoping review.Ethics and disseminationResearch ethics approval is not required for this scoping review. This review started off in October 2018, anticipated end date is June 2020. We plan to disseminate this research through publications, presentations at relevant national and international conferences and meetings with relevant stakeholders. This scoping review protocol has been registered at Open Science Framework (https://osf.io/tupbv).

Canadian Hand Dermatitis Management Guidelines

2010 ◽  
Vol 14 (6) ◽  
pp. 267-284 ◽  
Author(s):  
Charles Lynde ◽  
Lyn Guenther ◽  
Thomas L. Diepgen ◽  
Denis Sasseville ◽  
Yves Poulin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Treatment Options ◽  
Significant Loss ◽  
Treatment Modalities ◽  
Management Guidelines ◽  
Hand Dermatitis ◽  
Randomized Controlled Clinical Trials ◽  
Common Skin ◽  
Skin Conditions

Background: Hand dermatitis (HD) is one of the most common skin conditions; however, it is not a homogeneous disease entity. The severity of HD may range from very mild cases to severe chronic forms, which may result in prolonged disability and, occasionally, refractory HD. Chronic hand dermatitis (CHD) is associated with a high health- economic burden and significant loss of quality of life. Objective: Although numerous treatment options are available, the management of CHD is often difficult and unsatisfactory. There is a paucity of well-designed, randomized, controlled clinical trials in support of the efficacy of established treatment modalities. Conclusion: These guidelines cover the epidemiology, burden, quality of life, etiology, diagnosis, classification, and prevention of HD and provide guidance on management using an approach that is as evidence based as possible.

scholarly journals EFFECT OF SHODHANA AND SHAMAN CHIKITSA IN THE MANAGEMENT OF PSORIASIS: A CASE STUDY

2020 ◽  
Vol 11 (5) ◽  
pp. 36-39
Author(s):  
Vishal Aggarwal ◽  
Tinkle Rani ◽  
Arun Gupta
Keyword(s):  
Quality Of Life ◽  
Palliative Treatment ◽  
Treatment Options ◽  
Signs And Symptoms ◽  
Skin Condition ◽  
The Body ◽  
Whole Body ◽  
Treatment Modalities

Psoriasis is a visible skin condition of chronic origin substantially affecting the physical as well as psychological life of the person thus affecting the quality of life. To combat the same, modern medicine comes with varieties of treatment options but none of them fully cure neither give very promising results to improve quality of life. In Ayurveda, Psoriasis shares the correlation with Ekakushtha. The aim of this study is to evaluate the role of Ayurveda treatment modalities in Ekakushtha. A male patient aged 27 years presented with the signs and symptoms as well-defined, slightly raised silvery scales all over the body, mainly presented on flexors surfaces of bilateral legs, hands and over the trunk region along with severe dryness of whole body, powdery discharge with severe itching, diagnosed as Ekakushtha (chronic psoriasis) and was treated with both external and internal medications, which included Vaman Therapy (purificatory emesis) and Shamana (palliative treatment). Shodhana was given as Samyak Snehan (proper oleation) followed by Vamana Karma (therapeutic emesis), in which vitiated Doshas are expelled out through Urdhvamarga (through mouth) and Shamana was given by classical Ayurvedic medications. At the end of Vamana, Pittantik Vamana was achieved. Patient felt notable reduction from erythema, Kandu (itching) and scaling during treatment. This case study showed Vaman karma followed by palliative treatment to be a better treatment option which gives significant improvement in Psoriasis.

Self-Compassion and Quality of Life in Adults Who Stutter

2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd
Keyword(s):  
Quality Of Life ◽  
Social Connectedness ◽  
The Self ◽  
Future Research ◽  
Self Compassion ◽  
Adults Who Stutter ◽  
And Gender ◽  
Relationship Of ◽  
The Impact

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.

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