Mental and Psycho-social Health and Quality-of-Life Before and After Cardiac Rehabilitation: A Prospective Cohort Study With Comparison to Specific Population Norms

Abstract Background. Data on mental health improvement after cardiac rehabilitation (CR) are contradicting. The aim was to examine the mental and psycho-social health of patients admitted to our rehabilitation center following hospital treatment for acute coronary syndrome, before and after multidisciplinary CR.Methods. Outcome was measured at admission and discharge by the 36-Item Short Form Survey (SF-36), the Symptom Checklist-90 Revised (SCL-90R), the Coping Strategy Questionnaire (CSQ) and the 6-minute-walking distance test. The patients’ health status was compared with norms of sex-, age- and comorbidity-matched data from the German general population. Score differences from norms were measured by standardized mean differences (SMDs); health changes were quantified by standardized effect sizes (ESs). Their importance for comprehensive assessment was quantified by explorative factor analysis.Results. Of n=70 patients followed-up (male: 79%; mean age: 66.6 years), 79% had ≥3 comorbidities. At baseline, SF-36 Physical functioning (SMD=–0.75), Role physical (–0.90), Social functioning (SMD=–0.44), and Role emotional (SMD=–0.45) were significantly worse than the norm. After CR, almost all scores significantly improved by ES=0.23 (SCL-90R Interpersonal sensitivity) to 1.04 (SF-36 Physical functioning). The strongest factor (up to 41.1% explained variance) for health state and change was the mental health domain, followed by function&pain (up to 26.3%).Conclusions. Normative deficits in physical and psycho-social health were reported at baseline. After CR, at follow-up, all scores, except phobia, showed significant improvement. The comprehensive measurement of bio-psycho-social health should not be limited to depression and anxiety but include, especially, the somatization and social participation dimensions.

Download Full-text

A functional electric orthesis on the paretic leg improves quality of life of stroke patients

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2006000100005 ◽

2006 ◽

Vol 64 (1) ◽

pp. 20-23 ◽

Cited By ~ 9

Author(s):

Mara Renata Fernandes ◽

Luciane B.C. Carvalho ◽

Gilmar F. Prado

Keyword(s):

Quality Of Life ◽

Social Functioning ◽

Physical Functioning ◽

Bodily Pain ◽

Improve Quality ◽

Stroke Patients ◽

Normal Life ◽

Sf 36 ◽

Before And After

CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.

Download Full-text

The Reliability and Validity of the Health of the Nation Outcome Scales: Validation in Relation to Patient Derived Measures

Australian & New Zealand Journal of Psychiatry ◽

10.1080/j.1440-1614.2000.00755.x ◽

2000 ◽

Vol 34 (3) ◽

pp. 504-511 ◽

Cited By ~ 38

Author(s):

Robert Brooks

Keyword(s):

Mental Health ◽

Psychometric Properties ◽

Interrater Reliability ◽

New South ◽

Short Form ◽

Reliability And Validity ◽

The Third ◽

South Wales ◽

Sf 36 ◽

Before And After

Objective: The Health of Nation Outcome Scales (HoNOS) was developed to assess mental health outcomes. The aim of the studies is to examine the psychometric properties, reliability and validity of the HoNOS. Method: Three studies were conducted within St John of God Hospitals in New South Wales, Australia. They examined the reliability and the validity of the HoNOS. The first study examined the interrater reliability of the HoNOS, before and after staff training in the use of the HoNOS. The second study examined the validity of the HoNOS with the Symptom Checklist 90 Revised (SCL90-R) and the third study examined the validity of the HoNOS with the Short-Form 36 (SF-36). Results: The first study showed an improvement in the interrater reliability (IRR) of the HoNOS due to training. However, a generally unsatisfactory IRR (range 0.50–0.65) was achieved. The second study found no correlation between the SCL90-R and the HoNOS on admission (r = 0.04) and discharge (r = 0.06). The third study found no significant correlation between the Mental Component Score of the SF-36 and the HoNOS on admission (r = −0.033) nor on discharge (r = −0.104). Conclusions: The HoNOS has at best moderate interrater reliabilities. Further, the validity of the HoNOS is under question, that is, it does not correlate with a major measure of mental health symptoms, nor with a major measure of health status. As such, it is concluded that the psychometric properties of the HoNOS do not warrant its use as a routine measure.

Download Full-text

THE PECULIARITIES OF THE QUALITY OF LIFE OF PATIENTS, SUFFERED FROM ANEURYSMAL SUBARACHNOID HAEMORRHAGE

PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse ◽

10.21802/2304-7437-2019-5(57)-52-58 ◽

2019 ◽

pp. 52-58

Author(s):

K. V. Duve

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Emotional Disorders ◽

Physical Functioning ◽

Functional Dependence ◽

Control Group ◽

Aneurysmal Subarachnoid Haemorrhage ◽

Number Of Patients ◽

Sf 36

The analysis of data from a number of scientific sources shows that even those patients, with favorable outcomes after suffering from aneurysmal subarachnoid hemorrhage (aSAH), may often experience a decline in quality of life (QoL), both at the physical and psychosocial levels. The influence of functional dependence on the patient’s quality of life remains controversial, because among the number of patients, who save the ability of self-care, there exists a part of those, who are not able to return to their previous lifestyle, kind of activity, they have difficulties in their relationships and emotional disorders. The aim of study was to assess the quality of life of patients in recovery and residual periods of aSAH. Material and methods. We examined 114 patients (64.91 % - males, 35.09 % - females). The patients’ quality of life was studied by using the questionnaire SF-36. The control group consisted of 20 healthy participants, matched by age and gender. Results. The significant decrease in QoL of patients was observed in all scales, with the exception of physical functioning, vital activity and social functioning. It should be noted, that "mental health" scale rates correlated with the level of anxiety (r = -0,55) and depression (r = -0,61). In the different age groups, the QoL indicators were almost identical, with the exception of "physical functioning" component, because older patients received a lower score for this scale (p<0.01). Patients with a moderate level of disability were observed with a decline in all QoL categories of the scale SF-36. Patients, who were totally independent, had also a significant decline in all QoL scale components, with the exception of physical functioning. Conclusions. We found the decrease in QoL of patients in recovery and residual periods of aSAH, which does not depend on one’s level of functional dependence. The influence of anxiety (r = -0,55) and depression (r = -0,61) on the subscale "mental health" was established.

Download Full-text

Cerebral Targeting of Acupuncture at Combined Acupoints in Treating Essential Hypertension: An Rs-fMRI Study and Curative Effect Evidence

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2016/5392954 ◽

2016 ◽

Vol 2016 ◽

pp. 1-12 ◽

Cited By ~ 6

Author(s):

Yanjie Wang ◽

Yu Zheng ◽

Shanshan Qu ◽

Jiping Zhang ◽

Zheng Zhong ◽

...

Keyword(s):

Mental Health ◽

Synergistic Effect ◽

Acupuncture Treatment ◽

Brain Regions ◽

Short Term ◽

Curative Effect ◽

Brain Areas ◽

Fmri Study ◽

Sf 36 ◽

Before And After

The study attempted to explore that the synergistic effect of acupoints combination is not a simple superposition of single acupoint’s effect by comparing and analyzing the changes of blood pressure (BP), SF-36, and brain regions after acupuncture treatment. 47 patients were randomly divided into LR3+KI3 group, LR3 group, and KI3 group. Subjects received Rs-fMRI scan, BP measurement, and SF-36 questionnaires before and after treatment and short-term acupuncture treatment. After treatment, there were no significant differences in BP and SF-36 among 3 groups, compared to the case before treatment, SBP of 3 groups decreased, and DBP significantly decreased while vitality and mental health significantly increased in LR3+KI3 group. Both number and scopes of changes of brain regions in LR3+KI3 group were the largest, which mainly included BAs 3, 4, 8, 19, 21, 24, 32, 44, and 45. In conclusion, acupuncture at LR3+KI3 may auxiliarily reduce BP and improve the vitality and mental health of patients, and the changes of brain regions were related to somatesthesia, movement, vision, audition, emotion and mood, language, memory, etc. BAs 4, 9, 10, 24, 31, 32, and 46 may be the targeting brain areas of acupuncture in assisting hypotension. It is suggested that acupoints combination of LR3+KI3 maybe generates a synergistic effect, and it is not simple sum of single acupoint effect.

Download Full-text

Improved Health-Related Quality of Life in Patients with Hematological Disorders Receiving Deferasirox (Exjade®)

Blood ◽

10.1182/blood.v112.11.1307.1307 ◽

2008 ◽

Vol 112 (11) ◽

pp. 1307-1307 ◽

Cited By ~ 5

Author(s):

John B Porter ◽

Donald Bowden ◽

Arnold Ganser ◽

Gabor Domokos ◽

Adam Gater ◽

...

Keyword(s):

Mental Health ◽

Social Functioning ◽

Physical Functioning ◽

General Health ◽

Bodily Pain ◽

Hematological Disorders ◽

Role Emotional ◽

Role Physical ◽

Sf 36 ◽

Domain Scores

Abstract Introduction: Iron chelation therapy (ICT) is essential in removing excess iron deposited in body organs, ultimately preventing organ failure and extending the lives of patients (pts) with transfusion-dependent hematological disorders such as β-thalassemia and myelodysplastic syndromes (MDS). As a life-long treatment, traditional ICT (deferoxamine, Desferal®, DFO) is based on a burdensome regimen (subcutaneous delivery 5–7 times a week) that has been shown to negatively impact on pts’ health-related quality of life (HRQoL). The oral chelator deferasirox (Exjade®) is less burdensome to pts offering 24-hour ICT, 7 days a week. Methods: This substudy was part of a single arm, multicenter, 1-year open-label trial (the EPIC study) to investigate the efficacy/safety of deferasirox. The first 558 pts with a variety of hematological disorders were recruited. These pts came from sites in seven countries: Australia, Belgium, France, Germany, UK, Greece, and Italy. Treatment-naïve pts and those having previously received ICT (DFO or deferiprone [Ferriprox®] exclusively, or combined) participated (n=558). Pts were asked at baseline, week 4 and week 52 (end of study [EOS]) to complete the 36-item Short Form health survey (SF-36). The SF-36 is a self-administered questionnaire and measures eight HRQoL domains: physical functioning; role-physical; bodily pain; general health; vitality; social functioning; role-emotional; and mental health. Mean change in SF-36 domain scores were calculated for all pts who had completed data at baseline and week 4, as well all those with completed data at baseline and EOS. All domains are scored so that higher scores indicate a better QoL. Results: Overall, the mean age of the 558 pts (274 β-thalassemia, 168 MDS, 50 sickle cell disease and 66 other anemias) recruited to take part in this substudy was 40.8 years (SD=22.58); 51.5% of patients (n=289) were male and 48.5% (n=272) were female. Within this sample, 337 pts aged ≥16 years completed the SF-36 at baseline, 322 at week 4 and 277 at EOS. Mean domain scores for pts at baseline, week 4 and EOS are presented in Table 1. With the exception of role-emotional (mean=0.78, SD=40.56), mean change in SF-36 domain scores significantly improved (P<0.05) for all domains between baseline and week 4: physical functioning (mean=2.42, SD=17.44); role-physical (mean=5.67, SD=41.70); bodily pain (mean=5.96, SD=24.15); general health (mean=0.33, SD=14.44); vitality (mean=2.54, SD=15.93); social functioning (mean=2.51, SD=23.38); mental health (mean=1.98, SD=14.71). At EOS, mean change in SF-36 domain scores improved for all domains with the exception of social functioning, role-emotional and mental health. However, unlike results at week 4, none of the mean change domain scores at EOS reached statistical significance, possibly due to sample size decrease between week 4 and EOS. Table 1. SF-36 domain scores at baseline, week 4 and EOS in pts aged 3 16 years and treated with deferasirox SF-36 domains Baseline mean (SD) Week 4 mean (SD) End of study mean (SD) Physical functioning 66.32 (25.98)  n=336 69.70 (25.98)  n=317 71.67 (26.95)  n=275 Role-physical 54.33 (42.43) n=331 61.03 (42.69) n=315 62.38 (41.71) n=270 Bodily pain 65.80 (26.89)  n=336 74.67 (26.16)  n=322 73.11 (27.20)  n=276 General health 46.62 (21.15)  n=330 48.01 (22.32)  n=311 48.42 (22.19)  n=269 Vitality 51.12 (21.28)  n=328 54.57 (22.06)  n=316 55.80 (23.06)  n=272 Social functioning 71.73 (25.74)  n=336 74.77 (23.72)  n=321 73.05 (24.71)  n=276 Role-emotional 68.05 (40.92)  n=326 69.60 (41.60)  n=313 69.81 (40.44)  n=270 Mental health 67.04 (19.85)  n=328 70.40 (19.73)  n=316 67.85 (20.19)  n=272 Conclusions: Since mean change scores were often of the magnitude of 3 to 5 units for role-physical and bodily pain, these results indicate clinically meaningful improvement for pts with hematological disorders receiving deferasirox.

Download Full-text

FRI0492 СLINICAL AND LABORATORY DATA AND ALGORITHM OF MANAGEMENT OF ADULT PATIENTS WITH OLIGO-ARTICULAR VARIANTS OF JIA

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.1870 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 844.1-845

Author(s):

M. Dzhus ◽

M. Kyluk ◽

O. Ivashkivsky ◽

T. Karasevska

Keyword(s):

Mental Health ◽

Pain Intensity ◽

Normal Distribution ◽

Physical Functioning ◽

General Health ◽

Laboratory Data ◽

Well Being ◽

Adult Patients ◽

Psychological Status ◽

Sf 36

Background:The oligo-articular JIA is a disease that begins in childhood and can lead to joint damage and disability in adulthood with significant social losses.Objectives:The aim of this study was to evaluate the clinical and laboratory status and to develop an algorithm of managment adult patients with oligo articular variant of JIA, depending on the detection of RF or/and A-CCP, ANA, HLA-B27.Methods:The study included 168 adult patients from different regions of Ukraine who were diagnosed with JIA in childhood between 1984 and 2014 without severe comorbidities. Inclusion criteria were: age 16 to 60 years; duration of the disease > 3 years. Among patients with JIA were identified 64 patients with oligo-articular variant: 44 (26,2%) - with persistant oligo-arthritis, and 20 (11,9%) with extended oligo-arthritis. The disease activity was evaluated by DAS28 and JADAS-10. The questionaries SF-36, HAQ, TAS-20, PHQ-9 were analyzed and remote articular JADI-A and extra-articular JADI-E damages were evaluated. Statistical studies were performed using IBM SPPS Statistics version 25.0.0.0 software, the results were considered to be reliable at 5% critical level (P <0.05). The distribution of quantitative variables was tested by the Shapiro-Wilk test. Quantitative variables with a normal distribution were expressed as mean ± SD, quantitative variables that showed a non-normal distribution were expressed with a median (P25-P75), also performed correlative analysis of the variablesResults:It was found that patients with active JIA in 26.5% have depression according to the PHQ-9, while patients in remission have no signs of depression. Most adult patients with JIA (86.4%) have elevated and high levels of alexithymia. The predictors of JIA remission in adulthood are male sex (OR = 0.453; 95% CI 0.253-3.556); arthritis of more than 3 joints (OR = 0.459; 95% CI 0.347-0.770); wrist arthritis in childhood (OR = 0.082; 95% CI 0.009-0.739) and JADAS-10 in the disease onset (OR = 0.758; 95% CI 0.589-0.896) <6 points, treatment with IB in the history (OR = 0,767; 95% CI 0.054-0.811) and the duration of DMARDS treatment (OR = 0.741; 95% CI 0.636-0.863) > 1.5 years. The negative correlation of JADI-A and the patient’s physical well-being PCS (r = -0.27, p <0.05) and physical functioning (r = -0.24, p < 0.05), pain intensity (r = -0.24, p <0.05), general health (r = -0.24, p <0.05), vital activity (r = -0,19, p <0,05), social functioning (r = -0,27, p <0,05), mental health (r = -0,22, p <0,05) according to SF-36. The severity of extra-articular damages JADI-E correlated with PCS (r = -0.22, p <0.05) and physical functioning (r = -0.28, p<0.05), pain intensity (r = -0.20, p <0.05), general health (r = -0.23, p <0.05), and mental health (r = -0.23, p <0.05), but also had a positive correlation with HAM-A (r = 0.25, p <0.05), depression scale (r = 0.28, p <0.05) and PHQ-9 (r = 0.28, p <0.05). Significantly lower level of physical health was established in patients who requires prosthetics (p <0.001) compared to those who did not need prosthetics.Conclusion:Based on the obtained results, algorithms of management of adult patients with JIA oligoarthritis were developed, depending on the detected articular and extra-articular damages and the need for prosthetics and the psychological status.Disclosure of Interests:None declared

Download Full-text

THE PECULIARITIES OF THE QUALITY OF LIFE OF PATIENTS, SUFFERED FROM ANEURYSMAL SUBARACHNOID HAEMORRHAGE

PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse ◽

10.21802/10.21802/2304-7437-2019-5(57)-52-58 ◽

2019 ◽

pp. 52-58

Author(s):

K. V. Duve

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Emotional Disorders ◽

Physical Functioning ◽

Functional Dependence ◽

Control Group ◽

Aneurysmal Subarachnoid Haemorrhage ◽

Number Of Patients ◽

Sf 36

Download Full-text

Exercise Capacity, Nt-probnp And Adiponectin In Patients With Acute Coronary Syndrome Before And After Cardiac Rehabilitation As Well As At 12 Months

Medicine & Science in Sports & Exercise ◽

10.1249/01.mss.0000401274.33895.7f ◽

2011 ◽

Vol 43 (Suppl 1) ◽

pp. 461-462

Author(s):

Yuefei Liu ◽

Hong Jin ◽

Bernd Schweikert ◽

Harry Hahmann ◽

Lei Wang ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Cardiac Rehabilitation ◽

Exercise Capacity ◽

Coronary Syndrome ◽

Before And After

Download Full-text

A nxiety and depression influence the relation between disability status and quality of life in multiple sclerosis

Multiple Sclerosis Journal ◽

10.1191/1352458503ms930oa ◽

2003 ◽

Vol 9 (4) ◽

pp. 397-403 ◽

Cited By ~ 114

Author(s):

A CJW Janssens ◽

P A van Doorn ◽

J B de Boer ◽

N F Kalkers ◽

F GA van der Meché ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Multiple Sclerosis ◽

Physical Functioning ◽

Bodily Pain ◽

Depression Scale ◽

Anxiety And Depression ◽

Sf 36 ◽

Disability Status

Disability status, depression and anxiety are important determinants of quality of life (Q oL) in patients with multiple sclerosis (MS). We investigated whether anxiety and depression influence the relation between disability status and Q oL in our cohort of recently diagnosed patients. Disability status [Expanded Disability Status Scale (EDSS)], anxiety and depression [Hospital A nxiety and Depression Scale (HADS)], and Q oL (SF-36) were prospectively obtained in 101 MS patients. The relation between EDSS and SF-36 scales was examined using regression analyses, without and with adjustment for anxiety and depression. Interaction effects were investigated by comparing the relation between EDSS and Q oL in patients with high and low anxiety and depression. In the unadjusted analyses, EDSS was significantly related to all SF-36 physical and mental health scales. A fter adjustment for anxiety and depression, EDSS was significantly related only to the SF-36 physical functioning, role-physical functioning and bodily pain scales. The relation between EDSS and these SF-36 scales was consistently higher in patients with more symptoms of anxiety or depression, suggesting that anxiety and depression strengthened the association of EDSS in these SF-36 physical health scales. A fter adjustment for anxiety and depression, EDSS was not significantly related to the SF-36 mental health scales and the general health scale. This finding is compatible with the hypothesis that anxiety and depression are intermediate factors in the association of EDSS with these SF-36 scales. Screening for symptoms of anxiety and depression is recommended in studies that use Q oL as an outcome measure of treatment or intervention efficacy.

Download Full-text