A retrospective study on Tuberculous Lymphadenitis; A retrospective finding from multicenters referal hospitals

2020 ◽  
Author(s):  
Syed Ghouse Mohiuddin ◽  
Siti Maisharah ◽  
Orwa Albitar ◽  
Muhammad Shahid Iqbal ◽  
Amer Hayat Khan
Keyword(s):  
Retrospective Study ◽  
Treatment Outcomes ◽  
Univariate Analysis ◽  
Clinical Manifestations ◽  
P Value ◽  
Tuberculous Lymphadenitis ◽  
Age Group ◽  
Early Management ◽  
Unsuccessful Treatment ◽  
Multiple Variables

Abstract Background Extra-pulmonary tuberculosis (EPTB) represents about 14% of all cases of tuberculosis (TB) in Malaysia. The aims of the study include evaluation of socio-demographic factors, clinical manifestations, co-morbidities among patients with Tuberculous Lymphadenitis and their treatment outcomes.Methods The retrospective study was conducted from 2006 to 2008. Data on socio-demographic along with histopathological results were collected. Signs and symptoms were also recorded from TB registers, treatment cards and TB medical personal files using standard data collection tool. Among multiple variables significant factors identified by univariate analysis, were included in multivariate logistic regression to estimate the odds ratios (ORs) with the 95% confidence intervals (CIs). The statistically significant p value was considered as < 0.05.Results There were 348 (57%) males and on the other hand 262 (43%) females which shows almost equal incidence rate of Lymphadenitis in both genders. Mean age was found as 34.3 ± 14.6 years were majorly reported with positive diagnosis. 196 (32.1%) Malay was found with Tuberculous lymphadenitis followed by Chinese population of 148 (24.3%). Geographically from 386 (63.3%) urban population were found positive for lymphadenitis and over 224 (36.7%) of rural region. treatment outcome was observed 444 (72.8%) with successful treatment. WHO states the types of treatment failures and accordingly 85 (13.9%) patients were continued with the therapy that can be due to non-compliance or relapse of Tb. Among unsuccessful outcomes 194 patients of age group 26 -35 years, 65 (33.5%) were reported and 38 (29.7%) patients out of 128 between 16 – 25 years. Blood results showed erythrocyte sedimentation rate greater than 10 in 280 (45.9%) patients. Therefore, among 280 there were 115 (41.1%) patients found to have unsuccessful treatment showing strong association with p-value of <0.001.Conclusion Finding signifies that effect of weight loss on poor treatment outcomes` and active screening measures for patients with comorbidities are therefore recommended in patients with Tb lymphadenitis along with improvements in the diagnosis and early management of co-morbidities complications. As young age group were found to have poor or unsuccessful treatment outcomes and required aggressive strategy together with educating patients can further increase the treatment success rate.

scholarly journals Epidemiology of tuberculosis and treatment outcomes among children in Pakistan: a 5 year retrospective study

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5253 ◽  
Author(s):  
Madeeha Laghari ◽  
Syed Azhar Syed Sulaiman ◽  
Amer Hayat Khan ◽  
Naheed Memon
Keyword(s):  
Retrospective Study ◽  
Treatment Outcomes ◽  
Urban Areas ◽  
Demographic Data ◽  
Treatment Success ◽  
Clinical Manifestations ◽  
Sputum Smear ◽  
Unsuccessful Treatment ◽  
Patients At Risk ◽  
Group 2

Background Regardless of the advancement in medical technologies, the diagnosis of tuberculosis (TB) in children has remained a challenge. Childhood TB is rampant and an important cause of morbidity and mortality. The objective of this study was to determine the trend of TB and treatment outcomes in children aged ≤14 years registered for TB treatment under DOTS course in three districts of Sindh, Pakistan. Methods For this retrospective study, records of TB children (≤14 years) registered for the treatment of TB from January 2011 to December 2015 in three districts of Pakistan, were collected. Demographic data, baseline weight, clinical manifestations, radiography, histopathology results and treatment outcomes were collected from TB unit registers. Results A total of 2,167 children were treated for TB during the study period. Of these, 1,199 (55.3%) were females and 1,242 (57.3%) were from urban areas. Over three-quarter of patients (76.9%) had pulmonary TB with 13.3% of sputum smear positive cases. The overall treatment success rate was 92.4%. In multivariate analysis, rural residents (OR: 2.146, p < 0.001), sputum smear positive cases (OR: 3.409, p < 0.001) and re-treated patients (OR: 5.919, p < 0.001), were significantly associated with unsuccessful treatment outcomes. However, age group ≤2 years, male and those who were underweight were found to have the highest risk of pulmonary tuberculosis (OR: 1.953, p < 0.001; OR: 1.262, p = 0.028; OR: 1.342, p = 0.008), respectively. Conclusion Patients at risk of treatment failure must be given particular attention. Moreover, strategies are needed to further improve the diagnosis and treatment of TB among children and improve the recording system.

scholarly journals Predictors of Cerebral Arteriovenous Malformation Mortality: A Single-center, Five-year Retrospective Study

2021 ◽  
Vol 9 (3) ◽  
pp. 213-218
Author(s):  
Patricio Garcia-Espinosa ◽  
Edgar Botello-Hernández ◽  
Gabriela Torres-Hernández ◽  
Clarissa Guerrero-Cavazos ◽  
Estefania Villareal-Garza ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Univariate Analysis ◽  
International Classification Of Diseases ◽  
University Hospital ◽  
P Value ◽  
Predictors Of Mortality ◽  
The Hours ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
History Of

Background: Arteriovenous Malformations (AVMs) are abnormalities in intracranial vessels between the arterial and venous systems. This study aimed to identify the predictors of mortality in patients that presented to our hospital with AVMs, ruptured or unruptured, and correlate them to those available in the literature. Methods: An analytical, observational, retrospective study was performed to review data of patients with cerebral AVMs in the University Hospital “Dr José Eleuterio González” from January 2016 to December 2020. Clinical files were reviewed based on AVMs diagnosis according to the  International Classification of Diseases 10th Revision, ICD-10. Variables were subjected to a univariate analysis and those found significant (p-value < 0.05) were subjected to a logistic regression. Results: A total of 80 patients were included in our study. Most of the participants were females (56.3%) and three were pregnant. The most common presenting symptom was holocranial headache (34 cases) occurring between the hours of 22:00 to 7:00. The most significant predictors of mortality were a total bleeding volume greater than 9.18 cm3 (p = 0.010), the presence of more than one symptom (p = 0.041), and a history of previous cerebral intraparenchymal hemorrhage (p = 0.014). Conclusion: Results demonstrated an important association between intracranial bleeding and mortality. Ultimately, more prospective studies are needed to determine predictor factors for mortality in AVMs patients.

scholarly journals PROFIL KANDIDIASIS VULVOVAGINALIS DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. Dr. R. D. KANDOU MANADO PERIODE JANUARI - DESEMBER 2012

e-CliniC ◽  
2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Aljufri Syamsudin ◽  
Marlyn G. Kapantow ◽  
Renate T. Kandou
Keyword(s):  
Retrospective Study ◽  
Medical Records ◽  
Clinical Manifestations ◽  
Age Group ◽  
Dermatology Clinic

Abstract: Candidiasis vulvovaginalis (candida vulvovaginitis) is an infection of the vagina or vulva by Candida genus, with a variety of clinical manifestations that can occur acutely, chronically, or episodically. This study aimed to determine the profile of candidiasis vuvovaginalis in the Dermatology clinic Prof. Dr. R. D. Kandou Manado during the period of January to December 2012. This was a retrospective study using the medical records of new patients with a diagnosis of candidiasis vulvovaginalis. The results showed that there were 30 patients (2.73%) with candidiasis vulvovaginalis among 1096 new patients. It was more commonly found in women with the largest age group 25-44 years, residence in Manado, and as housewives, The most frequent therapy was systemic antifungals and antihistamine. The occurence of this disease was associated with other diseases such as bacterial vaginosis.Keywords: vulvovaginaliscandidosis, candida albicansAbstrak: Kandidiasis vulvovaginalis (kandidosis vulvovaginalis, kandida vulvovaginitis) adalah infeksi vagina dan atau vulva oleh Genus Candida, dengan berbagai manifestasi klinisnya yang bisa berlangsung akut, kronis atau episodik. Penelitian ini bertujuan untuk mengetahui profil kandidiasis vuvovaginalis di poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari – Desember 2012. Penelitian ini dilakukan secara retrospektif dari rekam medik pasien baru dengan diagnosis kandidiasis vulvovaginalis. Hasil penelitian menunjukkan bahwa terdapat 30 pasien (2,73%) kandidiasis vulvovaginalis dari 1.096 pasien baru, lebih banyak ditemukan pada perempuan dengan kelompok umur 25-44 tahun, didapatkan bahwa wilayah tempat tinggal terbanyak adalah Kota Manado, menurut pekerjaan paling banyak terjadi pada IRT (Ibu rumah tangga), terapi yang banyak digunakan adalah Antijamur sistemik+antihistamin, dan kombinasi kandidiasis vulvovaginalis dengan penyakit lain terbanyak yaitu kandidiasis vulvovaginalis + bakterial vaginosis.Kata kunci: kandidiasis vulvovaginalis, candida albican, penelitian retrospektif

scholarly journals Diagnostic Procedures, Diagnoses, and Treatment Outcomes of Patients with Presumptive Tuberculosis Pleural Effusion in Uzbekistan

2021 ◽  
Vol 18 (11) ◽  
pp. 5769
Author(s):  
Fazlkhan Abdugapparov ◽  
Ruzanna Grigoryan ◽  
Nargiza Parpieva ◽  
Sherali Massavirov ◽  
Anvar Riskiyev ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Treatment Outcomes ◽  
Diagnostic Procedures ◽  
Diagnostic Methods ◽  
P Value ◽  
Diagnostic Challenge ◽  
Tb Treatment ◽  
Unsuccessful Treatment ◽  
Co Morbidity ◽  
Multivariable Regression

Tuberculosis (TB) pleural effusion (TPE) is the second most common manifestation of extrapulmonary TB (EPTB), which remains a great diagnostic challenge worldwide. In Uzbekistan, there has been no formal evaluation of the actual practices of diagnosing and treating TPE. Our cohort study therefore aimed to describe the frequency and types of different diagnostic procedures of TPE during 2017–2018 and assess the association of baseline characteristics and establish diagnostic methods with TB treatment outcomes. In total, 187 patients with presumptive TPE were assessed, and 149 had a confirmed diagnosis of TPE (other diagnoses included cancer n = 8, pneumonia n = 17, and 13 cases were unspecified). TB was bacteriologically confirmed in 22 (14.8%), cytologically confirmed in 64 (43.0%), and histologically confirmed in 16 (10.7%) patients. Hepatitis was the only co-morbidity significantly associated with unsuccessful treatment outcomes (RR 4.8; 95%CI: 1.44–15.98, p value 0.011). Multivariable regression analysis showed that drug-resistant TB was independently associated with unsuccessful TB treatment outcome. (RR 3.83; 95%CI: 1.05–14.02, p value 0.04). Multidisciplinary approaches are required to maximize the diagnostic accuracy of TPE and minimize the chances of misdiagnosis. TPE patients with co-infections and those with drug resistance should be more closely monitored to try and ensure successful TB treatment outcomes.

scholarly journals PROFIL DERMATITIS ATOPIK DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R.D KANDOU MANADO PERIODE JANUARI 2010 - DESEMBER 2012

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Juan P. E. Febriansyah ◽  
Grace M. Kapantow ◽  
Agus Hariyanto
Keyword(s):  
Atopic Dermatitis ◽  
Retrospective Study ◽  
Topical Corticosteroid ◽  
Inflammatory Disease ◽  
Medical Records ◽  
Clinical Manifestations ◽  
Age Group ◽  
Trigger Factors ◽  
Infancy And Childhood ◽  
Almost All

Abstract: Atopic dermatitis (AD) is a chronic and recurrent inflammatory disease most commonly found during infancy and childhood. This disease is very complex and has a variety of clinical manifestations. Its management depends not only on the medication, but also on skin care and avoidance of trigger factors. This study aimed to obtain the profile of atopic dermatitis at the Dermatovenerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado period January 2010 to December 2012. This was a retrospective study using medical records of new registered patients at the Dermatovenerology clinic. New cases were grouped according to sex, age, occupation, treatment, and coinfection diseases. The results showed that there were 461 (16.26%) new cases of AD out of 2,835 cases, consisted of 289 (62.69%) females and 172 (37.31%) males with a ratio of 1.7:1. The most frequent age group was >12 years old (58.35%); they were commonly students (43.38%). The most frequent treatment was a combination of oral antihistamin and topical corticosteroid (49.67%). No coinfection was recorded among 332 cases (72.02%). Conclusion: Most of the atopic dermatitis cases at the Dermatovenerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado for the last 3 years were females, age group >12 years old, and as students. Combination of oral antihistamin and topical corticosteroid was the most common treatment. Almost all cases had no coinfection.Keywords: atopic dermatitis, profileAbstrak: Dermatitis atopik (DA) merupakan penyakit peradangan kulit kronis dan residif yang sering terjadi pada masa bayi dan kanak-kanak. Penyakit ini sangat kompleks dengan gambaran klinis bervariasi. Penatalaksanaannya tidak hanya bergantung pada pengobatan, namun juga perawatan kulit dan menghindari faktor pencetus. Penelitian ini bertujuan untuk mendapatkan profil DA di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2010 - Desember 2012. Metode penelitian ini retrospektif dengan menggunakan catatan medik pasien baru di Poliklinik Kulit dan Kelamin tersebut. Kasus baru dikelompokkan menurut jenis kelamin, usia, pekerjaan, pengobatan, dan penyakit penyerta. Hasil penelitian memperlihatkan 461 (16,26%) kasus baru DA dari 2.835 kasus baru, terdiri dari 289 (62,69%) perempuan dan 172 (37,31%) laki-laki dengan rasio 1,7:1. Kelompok usia terbanyak ialah >12 tahun sebesar 269 (58,35%), terbanyak pada pelajar/mahasiswa yaitu 200 kasus (43,38%). Terapi tersering ialah kombinasi antihistamin oral dan kortikosteroid topikal sejumlah 229 kasus (49,67%). Sejumlah 332 (72,02%) kasus tidak disertai penyakit lain. Simpulan: Kasus dermatitis atopik di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado selama 3 tahun terakhir tersering pada perempuan, kelompok usia >12 tahun, dan pada pelajar/mahasiswa. Kombinasi anti histamin oral dan kortikosteroid topikal menjadi terapi yang tersering diberikan. Sebagian besar kasus tidak disertai penyakit lain.Kata kunci: dermatitis atopik, profil

scholarly journals Tuberculosis Treatment Outcomes: A Fifteen Year Retrospective Study In Jos North And Mangu, Plateau State, North - Central Nigeria

2019 ◽  
Author(s):  
Comfort Nanbam Sariem ◽  
Patricia Odumosu ◽  
Maxwell Patrick Dapar ◽  
Jonah Musa ◽  
Luka Ibrahim ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Treatment Failure ◽  
Treatment Outcomes ◽  
Treatment Success ◽  
Infectious Agent ◽  
Tuberculosis Treatment ◽  
Patient Treatment ◽  
North Central ◽  
Unsuccessful Treatment ◽  
Plateau State

Abstract Background Tuberculosis (TB) disease is the leading cause of death from a single infectious agent globally. Medication adherence will be more valuable if it improves clinical/treatment outcomes of the patient because treatment outcomes are major indicators for evaluating TB therapy. Objective To examine a fifteen-year record of tuberculosis treatment outcomes in Jos North and Mangu Local Government Areas of Plateau State. Methods The retrospective registry based study was done in five TB treatment centers which account for more than half of data for tuberculosis patients in Plateau State, North-Central Nigeria. Data were collected from 10,156 TB patient’s health records from 2001 to 2015. Treatment outcomes were classified as successful (cured, treatment completed) or unsuccessful (non-adherent, treatment failure or death). Analysis was done descriptively and factors associated with treatment outcomes were determined using multiple logistic regression with the aid of Stata version 11. Results Males were 58.1% of the population (10,156). Mean age ±SD was 35.5±15.5 years. The overall treatment success rate was 67.4%; non-adherence/defaulting rate was 18.5%, with majority of patients defaulting at the end of intensive phase of treatment; sputum conversion rate was 72.8% and mortality rate was 7.5%. A decrease in successful treatment outcomes from 83.8% to 64.4%, with a corresponding increase in unsuccessful treatment outcomes was observed. After adjusting for sex, and TB category, being HIV positive was 2.8 times (95% CI: 1.11-6.83, p =0.028) more likely to be associated with treatment success than having an unknown status. TALF/RAD, relapse and MDR-TB were less likely associated with treatment success than newly diagnosed TB patients Conclusion Underlying reasons for medication non-adherence and treatment failure identified should be resolved by the patient, treatment supporter and health system through adherence counseling, increased education on voluntary counseling and testing of HIV among TB patients. Keywords: Tuberculosis, Treatment Outcomes, Retrospective Study, Nigeria

scholarly journals Nutritional status and TB treatment outcomes in Addis Ababa, Ethiopia: An ambi-directional cohort study

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247945
Author(s):  
Zekariyas Sahile ◽  
Robel Tezera ◽  
Damen Haile Mariam ◽  
Jeffrey Collins ◽  
Jemal Haider Ali
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Treatment Outcomes ◽  
Body Mass ◽  
Addis Ababa ◽  
Treatment Success ◽  
Sputum Smear ◽  
P Value ◽  
Tb Treatment ◽  
Unsuccessful Treatment

Background Remaining underweight during Tuberculosis (TB) treatment is associated with a higher risk of unsuccessful TB treatment outcomes and relapse. Previous studies conducted in Ethiopia found that bodyweight not adjusted for height at the start of treatment is associated with poor treatment outcomes. However, the association of body mass index (BMI) and weight change during treatment with treatment outcomes has not been studied. We aimed to investigate the association of BMI at the time of diagnosis and after two months of treatment and TB treatment outcomes. Methods Using an ambi-directional cohort study design (retrospective and prospective), a total of 456 participants were enrolled among 30 randomly selected public health centers residing within six sub-cities of Addis Ababa, Ethiopia. Data were collected using medical chart abstraction and face to face interviews. We compared TB treatment outcomes in persons with a body mass index (BMI) <18.5kg/m2 (underweight) versus persons with BMI ≥18.5kg/m2 (normal or overweight) at treatment initiation and after two months of treatment. Treatment was classified as successful in persons who were free of symptoms and had a negative sputum smear for acid-fast bacilli at the end of the 6-month treatment course. We analysed outcomes using univariable and multivariable logistic regression with 95% CI and p value< 0.05. Results Of enrolled study participants, 184 (40.4%) were underweight and 272 (59.6%) were normal or overweight. Body mass index (BMI ≥18.5kg/m2) at the start and second month of treatment were independent predictors for successful treatment outcome (AOR = 2.15; 95% CI: 1.05, 4.39) and (AOR = 3.55; 95% CI: 1.29, 9.73), respectively. The probability of treatment success among patients with BMI≥18.5kg/m2 at the start and second month of treatment was 92.9% and 97.1%, respectively versus 86.5% and 91.7% in patients with BMI<18.5kg/m2. Bodyweight not adjusted for height and change in the bodyweight after the second and sixth months of treatment were not significantly associated with treatment success. Conclusion In persons treated for TB disease, being underweight at baseline and after two months of treatment was a predictor for unsuccessful treatment outcomes. Nutritional assessment, counselling, and management are important components of TB treatment programs with the potential to improve treatment outcomes.

scholarly journals Clinico-Radiological Profile of Neurocysticercosis in Children

2019 ◽  
Vol 39 (1) ◽  
pp. 15-21
Author(s):  
Prem Lochan Prasad ◽  
Reetika Dawra ◽  
Surabhi Chandra
Keyword(s):  
Parietal Lobe ◽  
Tertiary Care ◽  
Taenia Solium ◽  
Clinical Manifestations ◽  
P Value ◽  
Diagnostic Study ◽  
Age Group ◽  
Number Of Patients ◽  
One Year ◽  
Parenchymal Disease

Introduction: Neurocysticercosis (NCC) is the most common parasitic disease of the nervous system caused by the larval stage of Taenia solium (also known as pork tapeworm). Clinical manifestations are pleomorphic and determined mainly by the location, number and viability of cysts as well as by the host response. Neuroimaging is the most useful diagnostic study for parenchymal disease.  Methods: The study was conducted in the Paediatric Ward of a tertiary care teaching institute, Bareilly, India. The study was conducted on 50 subjects. The study was a hospital based, prospective, observational study. All admitted children between one year to 18 years and diagnosed to have neurocysticercosis were included the study. Statistical analysis was done by single and double sample proportion test. P value of less than 0.05 was considered significant. Results: Maximum numbers of patients were in age group of five-14 years. Males (62%) were more commonly affected than females. Seizure was found to be the commonest presentation of NCC. In our study majority of cases were diagnosed by CT scan. 70% of the patients enrolled in this study demonstrated ring enhancing lesions on neuroimaging. Maximum number of patients had lesions in the parietal lobe followed by frontal lobe. Conclusions: NCC is common in the age group of five to 14 years. Focal seizures were the most common presentation. Other symptoms were headache and vomiting. Vegetarians were more commonly affected than non vegetarians. Single ring enhancing lesion in parietal area was the commonest neuroimaging findings.

scholarly journals Evaluation of Patients’ Satisfaction with the Complete Denture made in Prosthodontics Department of Dentistry Faculty, Tabriz, Iran 2017

2018 ◽  
Vol 6 (2) ◽  
pp. 9
Author(s):  
Seyed Amin Musavi ◽  
Hosein Eslami ◽  
Vahid Fakhrzadeh ◽  
Fatemeh Dabaghi-Tabriz ◽  
Mahdi Rahbar ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Class Ii ◽  
Complete Denture ◽  
P Value ◽  
Age Group ◽  
Class Iii ◽  
Significant Relation ◽  
Patient’S Satisfaction ◽  
Patients Satisfaction ◽  
Made In

Aim: In this study, patient’s satisfaction with complete denture made in prosthodontics department of Tabriz dentistry faculty was evaluated based on the residual alveolar ridge.Materials and methods: This retrospective study was carried out on 60 patients referred to the Prosthodontics Department of Tabriz Dentistry School by through completing questionnaires and clinical examination. Data from the study were analyzed using SPSS 17 software. In this study, p-value less than 0.05 were considered statistically significant. Results: In this retrospective study, 61.5 % of participants were male and mostly in the age group of 30 to 40 years. 43.3 % of patients had Ridge Class II, 56.7 % Class had ridge class III. None of the studied patients, had class four or one ridge. The results of present study showed well that satisfaction of patients, in some cases, has a significant relation according to the residual ridge conditions of the patient one and three months after delivery of prosthesis. Satisfaction rate was higher in patients with ridge class II. Moreover, satisfaction of patients showed an increase in three-month intervals.Conclusion: 38.4 % of patients sowed satisfaction with their new teeth three months after prosthesis delivery. Satisfaction of patients was because of chewing soft food; overall capability of chewing, talking easily, the retention of dentures and denture satisfaction was higher in patients with Class II boats.

Sign in / Sign up

Export Citation Format

Share Document