scholarly journals Prevalence and Risk Factors of Chronic Kidney Disease among Palestinian Diabetic Patients: a Cross Sectional Study

2020 ◽  
Author(s):  
Zaher Nazzal ◽  
Zakaria Hamdan ◽  
Donia Masri ◽  
Oday Abu-Kaf ◽  
Mohammad Hamad

Abstract Background Chronic kidney disease (CKD) is a worldwide public health problem and diabetes is one of major risk factor for its development and progression. The aim of this study is to assess the prevalence of chronic kidney disease in a cross-sectional population of patients with type 2 diabetes treated in primary health care centers in North West Bank. Methods Patients’ data including patient characteristics, creatinine level, blood pressure, HbA1c, and hypertension and diabetes duration was collected from primary health care centers. eGFR was calculated using the CKD-EPI equation. CKD was staged according to the Kidney Disease Improving Global Outcomes System (KDIGO) 2012 guidelines. Both univariate and multivariate statistical analysis was conducted using SPSS. Results The prevalence of chronic kidney disease among diabetic adults in North West Bank was found to be 23.6% (95% CI: 19.4%-28.1%) distributed as follows: 19.7% had stage 3 CKD, 2.6% had stage 4 CKD and 1.3% had stage 5 CKD. In multivariate logistic regression, CKD was significantly associated with hypertension [adjusted OR= 4.43, P value=0.005], smoking [adjusted OR= 2.1, P value=0.01], and age [adjusted OR= 1.1, P value <0.001] Conclusions CKD is highly prevalent among Palestinian diabetic adults. Co-morbid hypertension, smoking and older age were found to increase the probability of developing this condition. Intensive screening for diabetic patients to detect CKD at earlier stages and implementation of more aggressive treatment modalities for diabetes as well as other important risk factors, especially hypertension and smoking are recommended.

2020 ◽  
Author(s):  
Zaher Nazzal ◽  
Zakaria Hamdan ◽  
Donia Masri ◽  
Oday Abu-Kaf ◽  
Mohammad Hamad

Abstract Background: Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chronic kidney disease in a cross-sectional population of patients with type 2 diabetes in primary health centers in North West Bank.Methods: Patient data including patient characteristics, creatinine level, blood pressure, HbA1c, and hypertension and period of diabetes were obtained from primary health care centers. The eGFR has been determined using the CKD-EPI equation. CKD was staged according to the 2012 Kidney Disease Improving Global Outcomes Framework (KDIGO) guideline. Both univariable and multivariable statistical analysis was conducted using SPSS. Results: The prevalence of chronic kidney disease among diabetic adults in North West Bank was found to be 23.6% (95% CI: 19.4%-28.1%) divided as follows: 19.7% had stage 3 CKD, 2.6% had stage 4 CKD and 1.3% had stage 5 CKD. In multivariable logistic regression, CKD was significantly associated with Age ≥60 years [adjusted OR: 3.2, 95% CI: 1.8-5.9], hypertension [adjusted OR: 5.7, 95% CI: 2.2-15.2], and smoking [adjusted OR: 2.3, 95% CI: 1.3-4.2].Conclusions: CKD is very prevalent among diabetic adults in Palestine. Co-morbid hypertension, smoking and older age has been shown to increase the risk of developing CKD. Extensive screening for diabetic patients to diagnose CKD at an early stage and to follow more aggressive treatment methods for diabetes as well as other important risk factors, especially hypertension and smoking, is recommended.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Zaher Nazzal ◽  
Zakaria Hamdan ◽  
Dunia Masri ◽  
Oday Abu-Kaf ◽  
Mohammad Hamad

Abstract Background Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chronic kidney disease in a cross-sectional population of patients with type 2 diabetes in primary health centers in North West Bank. Methods Patient data including patient characteristics, creatinine level, blood pressure, HbA1c, and hypertension and period of diabetes were obtained from primary health care centers. The eGFR has been determined using the CKD-EPI equation. CKD was staged according to the 2012 Kidney Disease Improving Global Outcomes Framework (KDIGO) guideline. Both univariable and multivariable statistical analysis was conducted using SPSS. Results The prevalence of chronic kidney disease among diabetic adults in North West Bank was found to be 23.6% (95% CI: 19.4–28.1%) divided as follows: 19.7% had stage 3 CKD, 2.6% had stage 4 CKD and 1.3% had stage 5 CKD. In multivariable logistic regression, CKD was significantly associated with Age ≥ 60 years [adjusted OR: 3.2, 95% CI: 1.8–5.9], hypertension [adjusted OR: 5.7, 95% CI: 2.2–15.2], and smoking [adjusted OR: 2.3, 95% CI: 1.3–4.2]. Conclusions CKD is very prevalent among diabetic adults in Palestine. Co-morbid hypertension, smoking and older age has been shown to increase the risk of developing CKD. Extensive screening for diabetic patients to diagnose CKD at an early stage and to follow more aggressive treatment methods for diabetes as well as other important risk factors, especially hypertension and smoking, is recommended.


2019 ◽  
Vol 4 (5) ◽  

Background: Cardiovascular disease (CVD) is common in the general population, affecting many of adults above 40 years of age. It is a multi-factorial disease. Some risk factors; such as family history, gender, ethnicity and age cannot be changed. Other risk factors are modifiable including high blood pressure, high cholesterol and diabetes. Patients will not necessarily develop cardiovascular disease if they have a risk factor. But the more risk factors they have the greater the likelihood that they will, unless protective measures and actions are taken to modify their risk factors and work to prevent them compromising their heart health. Objectives: The objectives of this study were: to evaluate the adherence of major primary health care centers to the WHO-PEN Protocol 1, Package of essential noncommunicable (PEN) disease interventions for primary health care, recommendations;and to provide more accurate estimate of cardiovascular risk using hypertension, type 2 diabetes mellitus and tobacco use as entry points. Methods: A cross-sectional study involving 200 patients who were already diagnosed with NCDs was conducted atprimary health care centers. Data was collected retrospectively using a self-designed questionnaire based on the WHO- PEN checklist. Patients’ files were selected randomly. Results: Based on the analysis of whole cohort (200 cases). The prevalence of type 2 diabetes was 39% and hypertension was 28.5%, whereas 32.5% had both. There were only 17 smokers among patients representing 8.5% of the sample. Using WHO/ISH, WHO/International Society of Hypertension, Risk prediction charts; half of patients were in the tenyear cardiovascular risk category of less than 10%. On the other hand, 5% had a ten-year cardiovascular risk over 40%.49% of patients had a first-degree family history of heart disease? All patients were counseled on diet, exercise and smoking cessation. Conclusion: These results demonstrate high adherence to the WHO-PEN protocol in these two centers reflecting a high quality of care and follow-up. Furthermore, the medical records were fully filled with adequate information for each item. However, there were some deficiencies in the risk estimation, which should be documented for better counseling for patients with high risk.


2019 ◽  
Author(s):  
Muna Abdulkadr ◽  
Hailu Merga ◽  
Biru Abdissa ◽  
Lamessa Dube

Abstract Background Diabetes mellitus remains the leading cause of end stage renal disease in most countries in the world. In Ethiopia, renal complications of diabetes may remain unrecognized due to limited diagnostic resources. As a result, the studies that shows the prevalence of chronic kidney disease (CKD) and its risk factors among adult diabetics in Ethiopia are flimsy. Hence, this study was aimed at assessing the prevalence of chronic kidney disease and associated factors among diabetic patients who attended federal police hospital diabetic clinic in Addis Ababa. Methods Hospital based cross sectional study was conducted among 362 Diabetes Mellitus patients using systematic sampling method. Chronic kidney disease stage was categorized according to the classification system established by the National Kidney Foundation Kidney Disease out comes Quality Initiative and defined by Estimated Glomerular Filtration Rate (eGFR) <60ml/min/1.73m2. Analysis was performed using SPSS. The prevalence estimates for the reduced GFR and overall chronic kidney disease were obtained. Binary logistic regression was used to see associated factors with chronic kidney disease. Results The prevalence of chronic kidney disease diagnosed by Cockroft-Gault equation and Modification of Diet in Renal Disease equation was 14.6% and 7.7% respectively. Age 50-59 years (AOR= 4.0; 95% CI:1.2, 13) by Cockroft-Gault equation (CG), age 60-69 years (AOR=5.8 95%CI:1.5,21.0) by Modification of Diet in Renal Disease (MDRD) and (AOR;22.9 95%CI:7.1,74.2) by CG, age 70 years and above (AOR=4.7; 95 CI: 1.1, 19.7) by MDRD and (AOR= 22.9; 95%CI:7.1,74.2) by CG, BMI (AOR=2.2; 95% CI:1.6, 4.2) by CG, and previous kidney disease (AOR=6.2 95%CI:2.0,8.4) by MDRD and (AOR;4.6 95%CI:1.9,10.8) C-G equation were found to have a significant association with chronic kidney disease after an adjustment done using multivariate analysis. Conclusion The prevalence of chronic kidney disease among Diabetic patients in this study was high. Age, BMI and previous recurrent kidney disease were associated with Chronic Kidney Disease. Preventive measures like giving health education and screening of patients with risk factors should get more attention.


2018 ◽  
Vol 21 (05) ◽  
pp. 936-940
Author(s):  
Muhammad Saeed Siddiqui ◽  
Muhammad Aziz ◽  
Makki Ahmad Ali

Objectives: To determine the prevalence of controlled diabetes in registereddiabetic patients with Hemoglobin A1c (HbA1c) ≤ 7 or Fasting blood Sugar ≤ 130 mg/dl inthree primary Health Care Centers of Al- Ameer Ahmad Sector of Makkah. Methods: This studywas a descriptive study (cross sectional) started from 20 June 2012 to 30 September 2012. ThePrimary Health Care Centers randomly selected were AL-Zahir, Al-Hindavia and Kudai Al- Hijra.The sample size calculated was 320 patients with confidence level of 95% and confidenceinterval of 5. The cut of values adjusted for all diabetes mellitus patients was, haemogloblin A1c( HBA1c) ≤ 7 or fasting blood sugar (FBS) ≤ 130 mg/dl .Hypertension values were set as 140/90 mm of Hg. Results: Overall the age range was 25 – 87 (62) years and a mean of +/- SDof 58.66 +/- 11.97. Out of 320 diabetic patients selected (152 only diabetes + 168 patients ofdiabetes with hypertension) 21.25 % have disease under control. Most effected age range ofuncontrolled diabetes was 45-74 years. HbA1c test for study year was not done in 83.43 %cases. The age and Gender difference in two groups were not significant, however the resultsof controlled and non-controlled diabetic patients in three Primary Health Care Centers wassignificant (P <0.05 ). Conclusions: Diabetes Control programme at the level of Primary HealthCenters showed a very low level of success in study groups. There is a need to reconsider thecontrol strategy.


Author(s):  
Anita Marlina ◽  
Said Usman ◽  
Yusni Yusni ◽  
Maimun Syukri ◽  
Hanifa Yusuf

This research aims to analyze the risk factors associated of Chronic Kidney Disease (CKD). This research was conducted in Rumah Sakit Umum Cut Meutia (RSUCM) North Aceh. Based on the Law of the Republic of Indonesia No. 39 Year 2009 regarding the prevention and control of disease not contagious is an attempt to improve the health of the community through activities promotive and preventive. This research is a cross sectional analytic research with a retrospective approach, this research is by searching the previous data. The data used in this study are secondary data at Rumah Sakit Umum Cut Meutia (RSUCM), North Aceh Regency in 2019, which aims to analyze risk factors associated with Chronic Kidney Disease (CKD). This research was conducted at Rumah Sakit Umum Cut Meutia (RSUCM), North Aceh District from 8 to 9 June 2020. The population included in this study were all patients with chronic kidney disease who received treatment at the Cut Meutia General Hospital in North Aceh Regency for the period January - December 2019 as many as 640 people.There is a relationship between the status of the demographics on the gender with risk the occurrence of disease chronic kidney where p value 0,452. There is relationship between disease comorbid in hypertension with the risk of the occurrence of disease chronic kidney where p value by 0,000. The relationship between disease comorbid in diabetes risk the occurrence of disease chronic kidney where p value by 0,000.


2019 ◽  
Vol 6 (2) ◽  
pp. 526
Author(s):  
Mote Srikanth ◽  
Jeyapalan Kuppusamy ◽  
Hemachandar Radhakrishnan ◽  
Arun Prasath Palamalai

Background: Chronic kidney disease is distinguished by progressive loss of kidney function over a period of years in the end leading to irreversible kidney failure. CKD is a significant prognosticator of cardiovascular disease. Atherosclerosis is common in patients with risk factors associated with chronic kidney disease.Methods: It was a cross sectional study on CKD patients in a tertiary care hospital. About 90 CKD stage 3-5 patients aged above 18 years were enrolled in the study. Serum lipid profile, RFT, serum calcium, phosphorous, and BP were estimated among all the patient. Patient risk factors were noted and CIMT levels were compared accordingly.Results: Out of 90 patients, males were predominant. There was a significant positive correlation between stage 5 and CIMT (P value <0.001). Mean CIMT was higher in patients with type 2 Diabetes. Patients with higher phosphorous the mean CIMT was significantly higher.Conclusions: The CIMT is early marker for atherosclerosis. Author observed it was significantly higher in patients with stage 3 and 5 CKD. CIMT is a non- invasive marker which should be done in all patients with CKD which is cost effective.


2019 ◽  
Vol 9 (2) ◽  
Author(s):  
Ljubica Djukanović ◽  
Višnja Ležaić

Introduction. Academy of Medical Science of Serbian Medical Societyintroduced collaboration between Belgrade nephrologistsand general practitioners with the aim of examining the prevalenceof chronic kidney disease (CKD) in populations at risk as well as ofchecking whether collaboration with general practitioners contributedto implementation of regular CKD screening.Methods. The research encompassed two studies carried out infour Belgrade Primary Health Care Centers. The screening study involved619 patients at risk for CKD (348 with hypertension, 206 withdiabetes, 65 persons aged > 60 years without hypertension/diabetes)in whom glomerular filtration rate (eGFR) was estimated byMDRD formula, while urine dipstick test was used for detection ofproteinuria and albuminuria (Micral-test® strips).The second studywas retrospective analysis of medical records of 450 patients whowere examined in the screening study and whose blood pressureand eGFR recording were analyzed during three-year period.Results. In screening study, eGFR below 60 ml/min/1.73m2 wasdetected in 121 (19.55%) and albuminuria in 242 (39.10%) patients.During three-year retrospective study, percentage of patientswhose blood pressure and eGFR were recorded decreasedfrom 42% to 22% and from 42% to 18%, respectively. Multivariateregression analysis selected health center, systolic blood pressureand hypertension as the variables significantly associated with thenumber of years in which blood pressure was recorded, while malegender, health center, hypertension and basal eGFR as variablesassociated with the number of years in which eGFR was recorded.Conclusion. Despite collaboration between nephrologists andgeneral practitioners in screening study, the retrospective threeyearstudy revealed insufficient recording of blood pressure andeGFR in patients’ medical records.


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