scholarly journals Elevated thyroid-stimulating hormone is associated with poor sleep: a cross-sectional and longitudinal study

2021 ◽  
Author(s):  
Yuerong Yan ◽  
Jiaqi Li ◽  
Huairong Tang ◽  
Youjuan Wang ◽  
Weiwei Zhang ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Thyroid Stimulating Hormone ◽  
Poor Sleep ◽  
Subjective Sleep Quality ◽  
Cross Sectional ◽  
Tsh Secretion ◽  
Quality Sleep ◽  
Good Sleep ◽  
Stimulating Hormone

Abstract Purpose Poor sleep and the accompanying TSH (Thyroid Stimulating Hormone) elevation are not uncommon since TSH secretion is controlled by the circadian rhythm. However, the true relationship between poor sleep and TSH elevation is unclear, and hence we aimed to elucidate this association by cross-sectional and longitudinal studies. Methods Participants with isolated elevated and normal TSH concentration were recruited, and the Pittsburgh Sleep Quality Index (PQSI) was used to assess sleep status. The patients with isolated TSH elevation were followed up longitudinally, and TSH levels were remeasured when sleep status improved. Results The proportion of poor sleep and occasional poor sleep among subjects with isolated TSH elevation was significantly higher than that in subjects with normal TSH (70.24% vs. 49.58%, p = 0.001; 9.52% vs. 1.68%, p = 0.006), and the ratio of good sleep was obviously decreased in subjects with isolated TSH elevation than normal TSH (20.24% vs. 48.74%, p < 0.001). Patients with isolated TSH elevation had significantly higher PSQI scores in the subjective sleep quality, sleep latency, sleep duration, and habitual sleep efficiency dimensions than subjects with normal TSH (all p < 0.05). In the follow-up study, among patients with isolated TSH elevation at baseline, the ratio of TSH normalization in patients who slept better was significantly higher than that in patients who still slept poorly (85.42% vs. 6.45%, p < 0.001). Conclusion This study revealed isolated elevated TSH concentrations tends to normalize when sleep status improves, and we recommend that clinicians inquire about sleep status thoroughly and reexamine thyroid hormone levels when sleep status improves.

scholarly journals Sleep quality during home distancing in the COVID-19 pandemic in the Western Amazon

2021 ◽  
Vol 31 (3) ◽  
pp. 458-464
Author(s):  
Carlos Roberto Teixeira Ferreira ◽  
Francisco Naildo Cardoso Leitão ◽  
Maura Bianca Barbary de Deus ◽  
Italla Maria Pinheiro Bezerra ◽  
Rejane Rosas Barbary de Deus ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Subjective Sleep Quality ◽  
Cross Sectional ◽  
Web Based ◽  
Demographic Questionnaire ◽  
Significant Difference ◽  
Quality Sleep

Introduction: the COVID-19 pandemic incited unprecedented global restrictions on society’s behavior. Home detachment and isolation measures applied during the COVID-19 pandemic can result in problems with sleep quality. It is an important measure to reduce the risk of infection from the COVID-19 outbreak. Objective: to investigate the existence of a difference between the quality of sleep before and during the home distance imposed by the Covid-19 pandemic. Methods: cross-sectional web-based survey was sent using different conventional social media to collect data from the study population. The evaluated group was composed of 124 subjects, 57 of whom were male and 67 were female from the city of Rio Branco / AC. For this study, the Pittsburgh Sleep Quality Index questionnaire (PSQI-BR) and a socio-demographic questionnaire were used. The volunteers received a link along with the description and purpose of the study. Finally, data analysis was performed using SPSS 22.0 software. Results: sleep quality worsened significantly during home distance in four sleep components (subjective sleep quality, sleep latency, sleep drowsiness and overall PSQI score). During social distance, poor sleep was greater among respondents (OR = 5.68; 95% CI = 1.80–17.82; p = 0.70). Conclusion: the results indicated that there was a significant difference between the quality of sleep before and during home detachment and sleep disturbance and the subjective quality of sleep before and during the period of the outbreak of COVID-19 were the components that most worsened in the state of sleep

scholarly journals Sleep Quality and Associated Factors among Peoples with Epilepsy Who Have a Follow-Up at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia, 2019: An Institutional Based Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Kemeriya Adem ◽  
Tilahun Kassew ◽  
Addis Birhanu ◽  
Ayalew Abate
Keyword(s):  
Sleep Quality ◽  
Associated Factors ◽  
Addis Ababa ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Sectional Study ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Specialized Hospital

Background. Sleep is an active cyclic biological phenomenon and necessary for survival. Individuals who suffer from sleep disturbance are less productive, decreased performance, and negative effects on mental health. Despite there are different studies on sleep quality in Ethiopia, no studies have been conducted on magnitude and predictors of sleep quality among people with epilepsy in the study setting. Objective. To assess sleep quality and associated factors among people with epilepsy who have a follow-up at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia, 2019. Method. An institution-based cross-sectional study was employed from May-June 2019. Systematic random sampling following face to face interview technique was employed. Epi-data version 3.1 and SPSS version 25 statistical packages were used for data entry and analysis, respectively. Frequencies, proportions, means, SDs, and cross-tabulations were used to summarize descriptive statistics of the data and tables, texts, and graphs were used for data presentation. To identify association and significant predictor with the outcome variable, binary logistic regression was fitted. The variable which has statistical significance was identified on the basis of p values ≤ 0.05 and AOR with 95% confident intervals. Results. A total of 423 participants have been enrolled to the study with a response rate of 98.1%. The prevalence of poor sleep quality among peoples live with epilepsy was found 65.4% (95% CI: 61.0, 69.9). Being female (AOR=2.94; (95% CI; 1.79, 4.85)), having stress full life events (AOR=2.38; (95% CI; 1.43, 3.97)), nonadherent to AED medication (AOR=1.86; (95% CI; 1.05, 2.78), poly-therapy treatment (AOR=2.24; (95% CI; 1.05, 2.78)), poor seizer control (AOR=2.4; (95% CI; 2.21, 12.46)), comorbid medical illness (AOR=2.6; (95% CI; 1.18, 5.61)), and anxiety (AOR=2.54; (95% CI; 1.52,4.24)) were factors significantly associated with poor sleep quality. Conclusion. This study revealed that more than half of the study participants were found to have poor sleep quality. So, considering the regular assessment of sleep quality and factors associated followed with appropriate intervention is recommended among peoples living with epilepsy.

scholarly journals Central TSH Dysregulation in a Patient with Familial Non-Autoimmune Autosomal Dominant Hyperthyroidism Due to a Novel Thyroid-Stimulating Hormone Receptor Disease-Causing Variant

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 196
Author(s):  
Jasna Suput Omladic ◽  
Maja Pajek ◽  
Urh Groselj ◽  
Katarina Trebusak Podkrajsek ◽  
Magdalena Avbelj Stefanija ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Autosomal Dominant ◽  
Signs And Symptoms ◽  
Thyroid Stimulating Hormone ◽  
Ablation Therapy ◽  
Tsh Secretion ◽  
Tshr Gene ◽  
Adult Male Patient ◽  
Stimulating Hormone

Background and Objectives. Familial non-autoimmune autosomal dominant hyperthyroidism (FNAH) is a rare cause of childhood hyperthyroidism. It is caused by the thyroid-stimulating hormone receptor (TSHR) gene variants. So far, only around 40 families with FNAH have been reported. Patients with activating TSHR variants demonstrated the same classical signs and symptoms of hyperthyroidism as seen in patients with Graves’ disease. Since 2012, ablative therapy is recommended to avoid relapses of hyperthyroidism and its consequences. Case Presentation. We presented a young adult male patient with a novel heterozygous TSHR disease-causing variant p.Arg418Lys (c.1253G>A) in the exon 10, who presented with a mild but progressive FNAH, with a follow-up since infancy. Discussion. Constantly suppressed TSH, including during the euthyreosis in childhood and hypothyreosis after iodine ablation therapy, suggested central dysregulation of the TSH secretion.

scholarly journals Psychological Distress Induces Poor Sleep Quality: A Cross-Sectional Study of Pharmacy Students in Bandung City, Indonesia

2018 ◽  
Vol 11 (1) ◽  
pp. 369-375 ◽  
Author(s):  
Sofa D. Alfian ◽  
Henry Ng ◽  
Dika P. Destiani ◽  
Rizky Abdulah
Keyword(s):  
Psychological Distress ◽  
Sleep Quality ◽  
Undergraduate Students ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Cross Sectional Survey ◽  
Subjective Sleep Quality ◽  
Cross Sectional ◽  
Subjective Sleep

Introduction: Poor subjective sleep quality in undergraduate students has not been widely studied in Bandung city, Indonesia. Poor sleep quality has been related to a number of risk factors for poor health outcomes. Objective: To analyze the association between psychological distress and subjective sleep quality. Methods: A cross sectional survey was done in one of the universities of Bandung city, Indonesia. Data were collected from 290 undergraduate students selected through consecutive sampling. Pittsburg Sleep Quality Index (PSQI) and Kessler-10 questionnaire were administered. Results: The prevalence of psychological distress was well (43.1%), mild (28.6%), moderate (20.7%), and severe (7.6%). The overall sleep quality was poor and good in 84.5% and 15.5% of the students. There was a significant association between psychological distress and poor sleep quality (p=0.006). The multivariate analysis suggested that psychological distress was a predictor of poor sleep quality (OR 1.991; 95% CI, 1.311−3.026). Conclusion: There is a need for an awareness of the college resources to help manage the stress levels of students through effective coping strategy-related study habits.

scholarly journals Decrease in Sleep Duration and Poor Sleep Quality over Time Is Associated with an Increased Risk of Incident Non-Alcoholic Fatty Liver Disease

2022 ◽  
Vol 12 (1) ◽  
pp. 92
Author(s):  
Yoo Jin Um ◽  
Yoosoo Chang ◽  
Hyun-Suk Jung ◽  
In Young Cho ◽  
Jun Ho Shin ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Sleep Duration ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Alcoholic Fatty Liver ◽  
Increased Risk ◽  
Alcoholic Fatty Liver Disease ◽  
Good Sleep ◽  
Over Time

The impact of changes in sleep duration and sleep quality over time on the risk of non-alcoholic fatty liver disease (NAFLD) is not known. We investigated whether changes in sleep duration and in sleep quality between baseline and follow-up are associated with the risk of developing incident NAFLD. The cohort study included 86,530 Korean adults without NAFLD and with a low fibrosis score at baseline. The median follow-up was 3.6 years. Sleep duration and quality were assessed using the Pittsburgh Sleep Quality Index. Hepatic steatosis (HS) and liver fibrosis were assessed using ultrasonography and the fibrosis-4 index (FIB-4). Cox proportional hazard models were used to determine hazard ratios (HRs) and 95% confidence intervals (Cis). A total of 12,127 subjects with incident HS and 559 with incident HS plus intermediate/high FIB-4 was identified. Comparing the decrease in sleep duration of >1 h, with stable sleep duration, the multivariate-adjusted HR (95% CIs) for incident HS was 1.24 (1.15–1.35). The corresponding HRs for incident HS plus intermediate/high FIB-4 was 1.58 (1.10–2.29). Comparing persistently poor sleep quality with persistently good sleep quality, the multivariate-adjusted HR for incident HS was 1.13 (95% CI, 1.05–1.20). A decrease in sleep duration or poor sleep quality over time was associated with an increased risk of incident NAFLD, underscoring an important potential role for good sleep in preventing NAFLD risk.

scholarly journals Home confinement during the COVID-19: day-to-day associations of sleep quality with rumination, psychotic-like experiences and somatic symptoms

2020 ◽  
Author(s):  
Peter Simor ◽  
Bertalan Polner ◽  
Noemi Bathori ◽  
Rebeca Sifuentes Ortega ◽  
Anke Van Roy ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Negative Mood ◽  
Somatic Complaints ◽  
Temporal Association ◽  
Poor Sleep ◽  
Psychological Consequences ◽  
Subjective Experiences ◽  
Subjective Sleep Quality ◽  
Cross Sectional ◽  
Subjective Sleep

Due to the COVID-19 pandemic, populations from many countries have been confined at home for extended periods of time in stressful environmental and media conditions. Cross-sectional studies already evidenced deleterious psychological consequences, with poor sleep as a risk factor for impaired mental health. However, limitations of cross-sectional assessments are response bias tendencies, and the inability to track daily fluctuations in specific subjective experiences in extended confinement conditions. In a prospective study conducted across three European countries, we queried participants (N = 166) twice a day through an online interface about their sleep quality and their negative psychological experiences for two consecutive weeks. Focus was set on between-and within-person associations of subjective sleep quality with daytime experiences such as rumination, psychotic-like experiences, and somatic complaints about the typical symptoms of the coronavirus. Results show that daily reports of country-specific COVID-19 deaths predicted increased negative mood, psychotic-like experiences and somatic complaints during the same day, and decreased subjective sleep quality the following night. Disrupted sleep was globally associated with negative psychological outcomes during the study period, and a relatively poorer night of sleep predicted increased rumination, psychotic-like experiences, and somatic complaints the following day. This temporal association was unidirectional since daytime reports of negative mental experiences were not associated with poor sleep quality on the following night. Our findings show that night-to-night changes in sleep quality predict how individuals cope the next day with daily challenges induced by home confinement

scholarly journals Quality of sleep and use of computers and cell-phones among university students

2019 ◽  
Vol 65 (12) ◽  
pp. 1454-1458 ◽  
Author(s):  
Diogo von Gaevernitz Lima ◽  
Ana Claudia Garabeli Cavalli Kluthcovsky ◽  
Luiz Gustavo Rachid Fernandes ◽  
Giovane Okarenski
Keyword(s):  
Medical Students ◽  
Sleep Quality ◽  
Computer Use ◽  
Cell Phones ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Good Sleep

SUMMARY OBJECTIVE Evaluate the quality of sleep and its association with the use of computers and cell-phones among medicine and dentistry students. METHODS Cross-sectional and comparative study, which evaluated 425 students through a socioeconomic questionnaire, the Pittsburgh Sleep Quality Index(PSQI), and a questionnaire on their use of computers and cell phones. RESULTS Poor sleep quality was observed in 61.4% of medical students and in 60.1% of dentistry students. Medical students with poor sleep quality had a higher mean time of computer use at night when compared to those with good sleep quality (p=0.04), as well as for computer (p<0.001) and cell phone use (p<0.01) immediately before bedtime. Dentistry students with poor sleep quality had a higher average time of computer use before bedtime than those with good sleep quality (p=0.03). CONCLUSION Students should receive guidance on prevention strategies and quality of sleep care.

175 Household and Transnational Caregiving and Sleep in Latinx Adults: The modifying effects of employment status

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A71-A71
Author(s):  
Luciana Giorgio ◽  
Carmela Alcantara
Keyword(s):  
New York ◽  
Sleep Quality ◽  
Sleep Duration ◽  
Employment Status ◽  
Poor Sleep ◽  
Moderating Effects ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Quality Sleep ◽  
And Gender

Abstract Introduction Although caregiving is associated with shorter sleep durations and worse sleep quality, particularly among employed individuals, these studies have mostly examined household (i.e., child, adult) and domestic caregiving among majority non-Latinx White samples. Sending remittances, a form of transnational caregiving whereby financial support is provided to relatives in one’s country of origin, is associated with positive mental health among Latinxs, yet its association with sleep remains unexamined. We examined the association of household and transnational caregiving with sleep duration and quality, and explored the moderating effects of employment status on these relationships. Methods Using cross-sectional data of healthy Latinx adults in New York City (N=188), we conducted separate age and gender-adjusted linear regressions or logistic regressions to examine the association of caregiving and sleep duration, and poor sleep quality, respectively. Sleep duration (continuous) and sleep quality (fairly/very poor) were measured using two items from the PSQI. Household caregiving was defined as caregiving for children or adults in the household. Transnational caregiving was operationalized as sending remittances. Moderation was tested using employment status*caregiving cross-products in adjusted models. Results Participants were Mage=37.61(SD=14.07), 71.3% employed, 66.5% female, and 59.6% immigrants. Overall, 14.9% were household caregivers and 28.72% sent remittances. Household caregiving was not significantly associated with sleep duration or quality. Those who sent remittances reported on average sleeping 27.63 minutes less than non-remitters (b=-27.63,SE=13.93,p&lt;0.05). Sending remittances was associated with 2.30 increased odds of reporting poor sleep quality (OR:2.30; 95%CI:1.03-5.14.) Employment status was a significant moderator (p&lt;0.05). Among those who were employed, sending remittances was associated with 3 times higher odds of poor sleep quality (OR:3.00;95%CI:1.46-10.59) and 48.94 fewer minutes of sleep duration than non-remitters (b=-48.94,SE=15.72,p&lt;0.05). These relationships were not observed among unemployed Latinxs. Conclusion Transnational caregivers were more likely to report shorter sleep duration and poorer sleep quality than their counterparts, and this was only observed among employed vs. unemployed Latinxs. Household caregiving was not significantly associated with sleep. Employed transnational caregivers may have multiple jobs that further constrain opportunities for longer and high-quality sleep. Future studies should examine potential upstream factors (e.g., working conditions) that may limit employed, transnational caregivers’ ability to obtain adequate sleep. Support (if any):

scholarly journals Associations between sleep quality and its domains and insufficient physical activity in a large sample of Croatian young adults: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e021902 ◽  
Author(s):  
Lovro Štefan ◽  
Goran Sporiš ◽  
Tomislav Krističević ◽  
Damir Knjaz
Keyword(s):  
Physical Activity ◽  
Young Adults ◽  
Sleep Quality ◽  
Sleep Disturbances ◽  
Smoking Status ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Subjective Sleep Quality ◽  
Cross Sectional ◽  
Insufficient Physical Activity

ObjectivesThe main purpose of the present study was to explore the associations between sleep quality and insufficient physical activity.DesignCross-sectional.SettingFaculties in Croatia.Participants2100 university students (1049 men and 1051 women) aged 18–24 years were recruited.Primary outcomeTo assess the domains of sleep quality (independent variables) and ‘insufficient’ physical activity (dependent variable), we used previously validated Pittsburgh Sleep Quality Index and International Physical Activity questionnaires. Logistic regressions were used to calculate the associations between the sleep quality and ‘insufficient’ physical activity.ResultsWhen sleep quality domains were entered separately into the model, very bad subjective sleep quality (OR 3.09; 95% CI 1.50 to 6.56), >60 min of sleep latency (OR 2.17; 95% CI 1.39 to 3.39), <7 hours of sleep (OR 1.56; 95% CI 1.24 to 1.96), <65% of habitual sleep efficiency (OR 2.26; 95% CI 1.26 to 4.05), sleep disturbances >1/week (OR 1.61; 95% CI 1.03 to 2.52), use of sleep medication >1/week (OR 3.35; 95% CI 1.83 to 6.10), very big daytime dysfunction problem (OR 2.78; 95% CI 1.57 to 4.93) and poor sleep quality (1.53; 95% CI 1.23 to 1.91) were associated with ‘insufficient’ physical activity. When all sleep quality domains were entered simultaneously into the model, the same significant associations remained, except for sleep disturbances. Both models were adjusted for gender, body mass index, self-rated health, life satisfaction, socioeconomic status, presence or absence of chronic diseases, smoking status, binge drinking and psychological distress.ConclusionsOur results show that ‘poor’ sleep quality is associated with ‘insufficient’ physical activity in young adults. In order to improve, special strategies and policies that leverage ‘good sleep’ quality are warranted.

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