Assessment of the Prevalence and Associated Risk Factors of Pediatric Hydrocephalus in Diagnostic Centers in Addis Ababa, Ethiopia
Abstract Background: Hydrocephalus (HCP) is defined as pathophysiology with disturbed cerebrospinal fluid. Neither qualitatively nor quantitatively are there adequate data to determine the prevalence and incidence of HCP in the developing world. HCP is a treatable condition that when left untreated, has fatal consequences.Objective: The objective of this study was to assess the prevalence of pediatric HCP and associated risk factors in diagnostic centers in Addis Ababa.Methods: A cross-sectional facility-based study was conducted over a retrospective and prospective data collection periods. Children aged 5 years and below who came to the four diagnostic centers for MRI/CT examination were studied. The collected data were analyzed using binary logistic regression. Result: The retrospective study included 639(58%) males, 462 (42%) females, and 753 (68.4%) infants were aged younger than 24 months. The mean age calculated was 22.3 months. Children diagnosed with HCP were 245 (22.3%); of these HCP cases, 153(62.4%) were classified as non-communicating HCP. This study identified infants aged younger than 24 months to be significantly associated with HCP (P<0.05). Regarding the gender and age distribution of the prospective study, 57(57.6%) males, 42 (42.4%) females; a mean age of 24.9 months and 60 (60.6%) infants aged younger than 24 months were included. Children diagnosed with HCP were 23 (23.2%); of these HCP cases, 13(56.5%) were classified as non-communicating HCP. Inadequate consumption of folic acid and the familial association of HCP were found to be statistically significant (P<0.05). Conclusion: The results of this study suggest that the high prevalence of HCP was due to the high prevalence of aqueductal stenosis and neural tube defects; with a small contribution of post-infectious causes. The majority of infants who present with HCP were aged younger than 24months.