scholarly journals Current Perception Threshold Testing in Chronic Ankle Instability

2020 ◽  
Author(s):  
Ran Zhang ◽  
Xi Zhang ◽  
Yaping Chen ◽  
Weiqun Song
Keyword(s):  
Ankle Instability ◽  
Sensory Nerve ◽  
Chronic Ankle Instability ◽  
Nerve Fibers ◽  
Sensory Function ◽  
Control Group ◽  
Perception Threshold ◽  
Current Perception Threshold ◽  
Significant Difference ◽  
Healthy Control

Abstract Background: Damage to sensory input is one of the pathologies underlying chronic ankle instability (CAI). Therefore, it is necessary to evaluate the sensory function of patients with CAI. This study aims to quantitatively evaluate sensory nerve function in patients with CAI and healthy controls using current perception threshold (CPT) measurements.Methods: Fifty-nine subjects with CAI and 30 healthy control individuals participated in this study. CPT values at the anterior talofibular ligament region were tested on the injured and uninjured sides in CAI patients and on a random side in the healthy control group.Results: There were no significant differences in age, gender, height, weight or BMI between the CAI and healthy control groups. The CPT values did not show significant gender differences. The CPT values were not significantly correlated with age or BMI. Compared to the control group (250 Hz: 24.32±9.28, 5 Hz: 6.87±1.56), the CAI group had significantly higher CPT values on the injured (250 Hz: 42.83±28.49, 5 Hz: 23.43±18.53) and uninjured sides (250 Hz: 38.62±19.98, 5 Hz: 18.84±14.21) under 250 Hz and 5 Hz electrical stimuli (p<0.01). No significant difference was observed under 2000 Hz stimuli. There were correlations among CPT values at different frequencies (p<0.01).Conclusion: This study revealed increased sensory thresholds in injured and uninjured ankles of 250 Hz- and 5 Hz-related sensory nerve fibers among patients with CAI. The bilateral change in sensory threshold may indicate a central sensory modulation process.Level of Evidence: Level III, case-control study.

scholarly journals Current perception threshold testing in chronic ankle instability

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Ran Zhang ◽  
Xi Zhang ◽  
Yaping Chen ◽  
Weiqun Song
Keyword(s):  
Ankle Instability ◽  
Sensory Nerve ◽  
Chronic Ankle Instability ◽  
Sensory Function ◽  
Control Group ◽  
Healthy Controls ◽  
Perception Threshold ◽  
Current Perception Threshold ◽  
Significant Difference ◽  
Healthy Control

Abstract Background Damage to sensory input is an underlying pathology of chronic ankle instability (CAI). Therefore, it is necessary to evaluate the sensory function of patients with CAI. The present study quantitatively evaluated sensory nerve function in patients with CAI and healthy controls using current perception threshold (CPT) measurements, as well as the influence of sex, age, and body mass index (BMI) on CPT values and the relations between CPT frequencies. Methods Fifty-nine subjects with CAI and 30 healthy controls participated in this study. CPT values at the anterior talofibular ligament region were recorded on the injured and uninjured sides in CAI patients and on both sides in the healthy control group. Between group differences were compared. The influence of sex, age and BMI on CPT values was evaluated. Correlations between different frequencies were also studied. Results There were no significant differences in age, sex, height, weight or BMI between the CAI and healthy control groups. The CPT values did not show a significant difference by sex. The CPT values did not significantly correlate with age or BMI. Compared to the control group, the CAI group had significantly higher CPT values on the injured and uninjured sides under 250-Hz and 5-Hz electrical stimuli; the difference between the groups was significant (p < 0.01), and the effect size were large. No significant difference was observed under 2000-Hz stimuli. There were correlations between CPT values at different frequencies (p < 0.01), especially 250 Hz and 5 Hz. Conclusion The present study revealed increased sensory thresholds in 250-Hz- and 5-Hz-related sensory nerve fibres in the injured and uninjured ankles of patients with CAI. This increase may indicate dysfunction of A-delta and C fibres. Sex, age and BMI did not significantly impact CPT values. There were correlations between CPT values at different frequencies, especially 250 Hz and 5 Hz. Level of evidence Level III, case-control study.

scholarly journals Comparison of Electromyographic Activity of Anterior Tibial Muscles and Long Fibular in Athletes With and Without Chronic Ankle Instability

2020 ◽  
Vol 22 (4) ◽  
pp. 260-264
Author(s):  
Giovanna Piai Cezar ◽  
Barbara Pasqualino Fachin ◽  
Christiane de Souza Guerino Macedo
Keyword(s):  
Surface Electromyography ◽  
Ankle Instability ◽  
Functional Limitation ◽  
Chronic Ankle Instability ◽  
Control Group ◽  
Electromyographic Activity ◽  
Ankle Sprains ◽  
Muscle Recruitment ◽  
Significant Difference ◽  
Anterior Tibial

AbstractChronic ankle instability (ICT) is common in jumping sports, may alter muscle recruitment, result in functional limitations and recurrence of sprains in this joint. The purpose of the study was to compare the muscle recruitment of the anterior tibial and long fibular muscles of athletes with and without chronic ankle instability by means of surface electromyography. Thirty-four athletes were recruited, divided into instability group (GI: n=14) and control group (GC: n=20), of both sexes and from different sport modalities, aged between 18 and 27 years old, history of ankle sprain in the last 12 months and functional limitation established by the Cumberland Ankle Instability (CAIT) questionnaire, the recruitment of the anterior tibial and long fibular muscles was analyzed by surface electromyography during the lunge exercise. The results for GI and GC were, respectively: age 21.3±2.88 and 22.4±3.25, height 1.77±0.10 and 1.74±0.08, CAIT 17[12.2-19] and 29.5 [27-30] (p<0.001). The anterior tibial and long fibular muscle recruitment in GI was 111.1[62.5-165.4] and 68.2±29, respectively and in GC 106.8[79.8-230.5] and 54.4±26.4, without significant difference. ICT did not interfere in the recruitment of the anterior tibial and long fibular muscles during the lunge exercise in athletes. Keywords: Ankle. Sprains and Strains. Health Evaluation. ResumoA instabilidade crônica do tornozelo (ICT) é comum em esportes de saltos, pode alterar o recrutamento muscular, resultar em limitações funcionais e recidivas de entorses nesta articulação. O objeto do estudo foi comparar o recrutamento muscular dos músculos tibial anterior e fibular longo de atletas com e sem instabilidade crônica de tornozelo por meio da eletromiografia de superfície. Foram recrutados 34 atletas, divididos em grupo instabilidade (GI: n=14) e grupo controle (GC: n=20), de ambos os sexos e de diferentes modalidades esportivas, com idade entre 18 e 27 anos, história de entorse de tornozelo nos últimos 12 meses e limitação funcional estabelecida pelo questionário Cumberland Ankle Instability (CAIT), o recrutamento dos músculos tibial anterior e fibular longo foi analisado pela eletromiografia de superfície durante o exercício de agachamento afundo. Os resultados para GI e GC foram, respectivamente: idade 21,3±2,88 e 22,4±3,25, altura 1,77±0,10 e 1,74±0,08, CAIT 17[12,2–19] e 29,5 [27-30] (p<0,001). O recrutamento muscular do tibial anterior e fibular longo no GI foi 111,1[62,5-165,4] e 68,2±29, respectivamente e no GC 106,8[79,8-230,5] e 54,4±26,4, sem diferença significativa. A ICT não interferiu no recrutamento dos músculos tibial anterior e fibular longo durante a realização do exercício de agachamento afundo em atletas. Palavras-chave: Tornozelo. Entorses e Distensões. Avaliação em Saúde

scholarly journals Lower Extremity Muscle Activation in Patients With or Without Chronic Ankle Instability During Walking

2015 ◽  
Vol 50 (4) ◽  
pp. 350-357 ◽  
Author(s):  
Mark A. Feger ◽  
Luke Donovan ◽  
Joseph M. Hart ◽  
Jay Hertel
Keyword(s):  
Lower Extremity ◽  
Surface Electromyography ◽  
Muscle Activation ◽  
Ankle Instability ◽  
Chronic Ankle Instability ◽  
Control Group ◽  
Ankle Sprains ◽  
Activation Time ◽  
Peroneus Longus ◽  
Healthy Control

Context Ankle sprains are among the most common musculoskeletal injuries, and many individuals with ankle sprains develop chronic ankle instability (CAI). Individuals with CAI exhibit proprioceptive and postural-control deficits, as well as altered osteokinematics, during gait. Neuromuscular activity is theorized to play a pivotal role in CAI, but deficits during walking are unclear. Objective To compare motor-recruitment patterns as demonstrated by surface electromyography amplitudes between participants with CAI and healthy control participants during walking. Design Descriptive laboratory study. Setting Laboratory. Patients or Other Participants Fifteen adults with CAI (5 men, 10 women; age = 23 ± 4.2 years, height = 173 ± 10.8 cm, mass = 72.4 ± 14 kg) and 15 matched healthy control adults (5 men, 10 women; age = 22.9 ± 3.4 years, height = 173 ± 9.4 cm, mass = 70.8 ± 18 kg). Intervention(s) Participants walked shod on a treadmill while surface electromyography signals were recorded from the anterior tibialis, peroneus longus, lateral gastrocnemius, rectus femoris, biceps femoris, and gluteus medius muscles. Main Outcome Measure(s) Preinitial contact amplitude, postinitial contact amplitude, time of activation relative to initial contact, and percentage of activation time across the stride cycle were calculated for each muscle. Results Time of activation for all muscles tested occurred earlier in the CAI group than in the control group. The peroneus longus was activated for a longer duration across the entire stride cycle in the CAI group (36.0% ± 10.3%) than the control group (23.3% ± 22.2%; P = .05). No differences were noted between groups for measures of electromyographic amplitude at either preinitial or postinitial contact (P &gt; .05). Conclusions We identified differences between the CAI and control groups in the timing of muscle activation relative to heel strike in multiple lower extremity muscles and in the percentage of activation time across the entire stride cycle in the peroneus longus muscle. Individuals with CAI demonstrated neuromuscular-activation strategies throughout the lower extremity that were different from those of healthy control participants. Targeted therapeutic interventions for CAI may need to be focused on restoring normal neuromuscular function during gait.

scholarly journals Evaluation of Oral Stereognosis in Relation to Tactile Ability and Patient Satisfaction

2017 ◽  
Vol 43 (6) ◽  
pp. 468-475
Author(s):  
Leblebicioglu Kurtulus Ikbal ◽  
Kilic Kerem ◽  
Eraslan Ravza ◽  
Unlu Damla ◽  
Çalışkan Ahmet ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
Complete Denture ◽  
Sensory Function ◽  
The Other ◽  
Control Group ◽  
Complete Dentures ◽  
Perception Threshold ◽  
Pressure Threshold ◽  
Significant Difference ◽  
Oral Perception

We investigated the oral stereognostic ability (OSA) of dentate individuals, conventional complete denture patients, and maxillary implant-supported denture patients with bar attachments. Stereognosis tests were carried out, and the relationship between OSA and patient satisfaction was assessed with a satisfaction survey: the Turkish version of the oral health impact profile-14 (OHIP-TR-14). To compare differences in oral sensory function among individuals with natural dentition, complete denture wearers, and maxillary implant-supported denture wearers, tactile awareness (thickness perception threshold) and pressure awareness (threshold of lateral loading) were assessed. According to the results, the oral perception level of natural dentate patients was higher than that of the complete denture group and maxillary implant-supported complete denture group at the end of the study. There was no statistically significant difference in OHIP-TR-14 scores between the maxillary implant-supported complete denture group and the complete denture group (P &lt; .05). The control group perceived the applied lateral and vertical forces statistically earlier than the other groups (P &lt; .001). There was no statistically significant difference between the complete denture and maxillary implant-supported denture groups in terms of the lateral pressure threshold or thickness tactile threshold (P &gt; .05). At the end of the study it was concluded that there was no correlation between oral perception levels and satisfaction in patients with complete dentures and patients with maxillary implant-supported complete dentures. The control group, compared with the complete denture and maxillary implant-supported complete denture groups, perceived the lateral and vertical forces statistically earlier than the other groups.

Quantitative Analysis of Deltoid Ligament Degradation in Patients With Chronic Ankle Instability Using Computed Tomographic Images

2021 ◽  
pp. 107110072199707
Author(s):  
Yasunari Ikuta ◽  
Tomoyuki Nakasa ◽  
Junichi Sumii ◽  
Akinori Nekomoto ◽  
Nobuo Adachi
Keyword(s):  
Ankle Instability ◽  
Ct Images ◽  
Chronic Ankle Instability ◽  
Control Group ◽  
Deltoid Ligament ◽  
Anterior Talofibular Ligament ◽  
Mri Findings ◽  
Calcaneofibular Ligament ◽  
Level Of Evidence ◽  
Strong Negative Correlation

Background: Rotational ankle instability (RAI) is associated with the faster onset of severe ankle osteoarthritis via dysfunction of the anterior talofibular ligament, calcaneofibular ligament, and deltoid ligament. No specific clinical examination is available for RAI, and diagnostic imaging has limitations in evaluating ligament degradation. This study investigated the deltoid ligament degeneration using Hounsfield unit (HU) values on computed tomography (CT) images. Methods: Patients were enrolled in this retrospective analysis if they had undergone magnetic resonance imaging (MRI) and CT scans of the ankle. The chronic ankle instability (CAI) group comprised 20 ankles with CAI (9 men, 11 women; mean age, 28.7 years) and the control group comprised 28 ankles (16 men, 12 women, mean age, 41.3 years). The average HU values of the deep posterior tibiotalar ligament (dPTL) that constitutes the deltoid ligament were measured on coronal CT images, and MRI results were used as a reference. All patients were subdivided based on the MRI findings of dPTL injury such as fascicular disruption, irregularity, and the loss of striation. Results: A strong negative correlation was identified between age and HU values for all patients (Spearman ρ = −0.63; P < .001). The mean HU values of the dPTL for participants aged <60 years were 81.0 HU for the control group (21 ankles) and 69.5 HU for the CAI group ( P = .0075). No significant differences in the HU values were observed for the dPTL among the MRI subgroups. Conclusion: In addition to the conventional imaging examination such as stress radiographs and MRI, HU measurements of CT images could be useful for quantitatively and noninvasively evaluating degenerative changes in the deltoid ligament for CAI patients to assist the diagnosis of RAI. Level of Evidence: Level III. case-control study.

scholarly journals Talar and Subtalar T1ρ Relaxation Times in Limbs with and without Chronic Ankle Instability

Cartilage ◽  
2021 ◽  
pp. 194760352199462
Author(s):  
Kyeongtak Song ◽  
Brian Pietrosimone ◽  
Joshua N. Tennant ◽  
Daniel B. Nissman ◽  
Katherine M. Dederer ◽  
...  
Keyword(s):  
Ankle Instability ◽  
Relaxation Times ◽  
Chronic Ankle Instability ◽  
Talar Dome ◽  
Contralateral Limb ◽  
Secondary Purpose ◽  
Healthy Control ◽  
Control Limb ◽  
Proteoglycan Content ◽  
Magnetic Resonance Imaging Mri

Objective The primary aim was to determine differences in talocrural and subtalar joint (STJ) articular cartilage composition, using T1ρ magnetic resonance imaging (MRI) relaxation times, between limbs in individuals with unilateral chronic ankle instability (CAI) and compare with an uninjured control. Our secondary purpose was to determine the association between talocrural and STJ composition in limbs with and without CAI. Design T1ρ MRI relaxation times were collected on 15 CAI (11 females, 21.13 ± 1.81 years, body mass index [BMI] = 23.96 ± 2.74 kg/m2) and 15 uninjured control individuals (11 females, 21.07 ± 2.55 years, BMI = 24.59 ± 3.44 kg/m2). Talocrural cartilage was segmented manually to identify the overall talar dome. The SJT cartilage was segmented manually to identify the anterior, medial, and posterior regions of interest consistent with STJ anatomical articulations. For each segmented area, a T1ρ relaxation time mean and variability value was calculated. Greater T1ρ relaxation times were interpreted as decreased proteoglycan content. Results Individuals with CAI demonstrated a higher involved limb talocrural T1ρ mean and variability relative to their contralateral limb ( P < 0.05) and the healthy control limb ( P < 0.05). The CAI-involved limb also had a higher posterior STJ T1ρ mean relative to the healthy control limb ( P < 0.05). In healthy controls ( P < 0.05), but not the CAI-involved or contralateral limbs (p>0.05), talocrural and posterior STJ composition measures were positively associated. Conclusions Individuals with CAI have lower proteoglycan content in both the talocrural and posterior STJ in their involved limbs relative to the contralateral and a healthy control limb. Cartilage composition findings may be consistent with the early development of posttraumatic osteoarthritis.

scholarly journals Bilateral Proprioceptive Evaluation in Individuals With Unilateral Chronic Ankle Instability

2017 ◽  
Vol 52 (4) ◽  
pp. 360-367 ◽  
Author(s):  
Andreia S. P. Sousa ◽  
João Leite ◽  
Bianca Costa ◽  
Rubim Santos
Keyword(s):  
Outcome Measure ◽  
Ankle Instability ◽  
Position Sense ◽  
Chronic Ankle Instability ◽  
Joint Position Sense ◽  
Control Group ◽  
Injured Limb ◽  
History Of ◽  
Ankle Proprioception ◽  
Force Sense

Context:  Despite extensive research on chronic ankle instability, the findings regarding proprioception have been conflicting and focused only on the injured limb. Also, the different components of proprioception have been evaluated in isolation. Objective:  To evaluate bilateral ankle proprioception in individuals with unilateral ankle instability. Design:  Cohort study. Setting:  Research laboratory center in a university. Patients or Other Participants:  Twenty-four individuals with a history of unilateral ankle sprain and chronic ankle instability (mechanical ankle instability group, n = 10; functional ankle instability [FAI] group, n = 14) and 20 controls. Main Outcome Measure(s):  Ankle active and passive joint position sense, kinesthesia, and force sense. Results:  We observed a significant interaction between the effects of limb and group for kinesthesia (F = 3.27, P = .049). Increased error values were observed in the injured limb of the FAI group compared with the control group (P = .031, Cohen d = 0.47). Differences were also evident for force sense (F = 9.31, P &lt; .001): the FAI group demonstrated increased error versus the control group (injured limb: P &lt; .001, Cohen d = 1.28; uninjured limb: P = .009, Cohen d = 0.89) and the mechanical ankle instability group (uninjured limb: P = .023, Cohen d = 0.76). Conclusions:  Individuals with unilateral FAI had increased error ipsilaterally (injured limb) for inversion movement detection (kinesthesia) and evertor force sense and increased error contralaterally (uninjured limb) for evertor force sense.

scholarly journals Investigation on Glucose and levels of Zn and Cu in Sera of Iraqi Males addicted on Methamphetamine or Tramadol

2021 ◽  
Vol 3 (2) ◽  
pp. 52-63
Author(s):  
Rulla Sabah ◽  
Ahmed saad abbas Fatin F.Al-Kazazz ◽  
Salam A.H Al-Ameri
Keyword(s):  
Chronic Disease ◽  
Normal Weight ◽  
Control Group ◽  
Healthy Group ◽  
Significant Difference ◽  
Zn And Cu In ◽  
Healthy Control ◽  
Group A ◽  
Age Range ◽  
Heavy Smokers

Addiction is the most critical form of Addiction. It is a chronic disease with a potential for fatality if not treated. In this work, 180 samples of male individuals were collected in this study. They classified into three groups, groups:  G1 who were healthy control; G2 who was addicted to methamphetamine (meth); G3 who was addicted to tramadol (Tra). Each group consists of 60 heavy smokers Iraqi male individuals in the age range of 18-43 years. The results showed a highly significant increase (p<0.0001) in the level of Glucose of the two addicted groups in comparison with the healthy group. A highly significant decrease (p<0.0001) could be seen in the level of Zn of the two addicted groups G2, G3 compared to the control group, while the level of Cu of the two addicted groups were highly significant increased (p<0.0001). Also, the results showed a highly significant difference (p<0.0001) in BMI for the studied groups, G2, G3 in comparison with the control group. All addictive individuals under this study were at normal weight depending on their BMI.  

scholarly journals Influence of Foot Progression Angle on Center of Pressure During Stair Ascending in Subjects With Chronic Ankle Instability

2021 ◽  
Vol 15 ◽  
pp. 350-354
Author(s):  
Jung-Hyun Ban ◽  
Tae-Ho Kim
Keyword(s):  
Center Of Pressure ◽  
Ankle Instability ◽  
Chronic Ankle Instability ◽  
Foot Progression Angle ◽  
Significant Difference ◽  
The Stability ◽  
Neutral Posture ◽  
Criteria For Selection ◽  
Anterior Posterior ◽  
Selection Of

The purpose of this study was to identify changes in the center of pressure during stair ascending in subjects with chronic ankle instability while different angles of foot are applied. The subjects of this study were 20 male and female adults with chronic ankle instability were selected from among the employees of D Hospital in Daegu Metropolitan City. The criteria for selection of subjects with chronic ankle instability were those who felt wobbling in the ankle joint and scored not higher than 24 points in a test using the Cumberland Ankle Instability Tool (CAIT). The subjects carried out stair ascending in neutral, toe-in and toe-out postures, respectively, and changes in the center of pressure (COP) were compared and analyzed. The results of this study, no statistically significant difference appeared in the comparison between the toe-in posture and neutral posture or between the neutral posture and the toe-out posture but medial/lateral movements of the center of pressure showed significant differences between the toe-in and toe-out postures. In addition, the total travel range and the moving range of the center of pressure, the average velocity, and the anterior/posterior movements of the center of pressure showed no statistically significant difference among all three postures. As a result, it could be seen that when adults with chronic ankle instability climb the stairs, the toe-in posture reduce the medial/lateral movements of the center of pressure thereby increasing the stability of the ankle and effectively preventing re-injuries.

scholarly journals Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Patients with RetinalArtery Occlusion

2020 ◽  
Author(s):  
Mahmut Atum ◽  
Gürsoy Alagöz
Keyword(s):  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Control Group ◽  
Retrospective Case ◽  
Control Subjects ◽  
Gender And Age ◽  
Significant Difference ◽  
Healthy Control ◽  
Retinal Artery ◽  
The Relationship

Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and plateletto- lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. Methods: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated. Results: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P > 0.05). Patients with RAO had significantly increased NLR values (2.85 ± 1.70) than the control subjects (1.63 ± 0.59, P < 0.001). The mean PLR in patients with RAO was 123.69 ± 64.98, while that in control subjects was 103.08 ± 36.95; there was no significant difference between the two groups (P = 0.055). A logistic regression analysis revealed that NLRs were 3.8 times higher in patients with RAO than in control subjects (odds ratio = 3.880; 95% confidence interval = 1.94 to 7.74; P < 0.001). Conclusion: NLRs were significantly increased in patients with RAO compared to the control subjects.

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