scholarly journals Analysis of Peripherally Inserted Central Catheter-Related Complications and Causes: a Retrospective Study of 2974 Children Blood Disease Patients in Single Center in China

2020 ◽  
Author(s):  
Li-Xian Chang ◽  
Yu-Wen Chen ◽  
Meng-Chuan Wang ◽  
Su-Yu Zhao ◽  
Min Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Insertion Site ◽  
Infectious Complications ◽  
Important Risk Factor ◽  
Large Sample Size ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Single Center ◽  
Blood Disease

Abstract Background: The peripherally inserted central catheter (PICC) has been widely used. However, there is still a lack of large sample size-based relevant risk factor investigation in children with blood diseases in china. Methods: We performed a retrospective, the single-center cohort study of child blood disease patients with PICC insertion. Totally, 2974 patients were enrolled for our study. Results: B-ultrasound plus Seldinger technology significantly improved the success rate of PICC insertion. The most common non-infectious complications were rash, followed by catheter blockage, mechanical phlebitis, and catheter broke. the male, 1-3 years old, Power PICC solo catheter and spring are risk factors for the rash. The power PICC solo catheter was the most important risk factor for catheter blockage. Insertion site under the elbow was the most important risk factor for phlebitis and catheter damage. Conclusion: Our finding first shed new light on the risk factors associated with PICC complications for Chinese blood disease children.

Exploring the Risk Factors of Thrombosis and Bloodstream Infections in Peripherally Inserted Central Catheter (PICC) Patients

2019 ◽  
Vol 9 (7) ◽  
pp. 929-934 ◽  
Author(s):  
Zhiping Liu ◽  
Jiangqiong Chen ◽  
Liping Zan ◽  
Hongjie Yi ◽  
Shenglan Ding ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Bloodstream Infections ◽  
General Information ◽  
Drug Prevention ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Stratified Care ◽  
The Difference ◽  
Medical Histories

Objective: To analyze the risk factors of thrombosis and associated bloodstream infections in patients with a peripherally inserted central catheter (PICC). Method: A total of 711 patients who received a PICC in our hospital between February and December 2018 were enrolled in this study. Clinically relevant data were collected, including general information, medical histories, laboratory examinations, etc. The 711 patients underwent risk assessments for thrombosis and bloodstream infections to statistically analyze the relevant risk factors. Result: Thirty-three of the 711 patients developed thrombosis, which is a proportion of 4.64%. In addition, ten patients developed bloodstream infections at an infection rate of 1.41%. For patients with different catheter indwelling times, the difference in the proportion of bloodstream infections was statistically significant (p < 0.05). Additionally, the analysis results showed that a difference in the vein-puncture site and the fibrinogen content is a direct risk factor for thrombosis. Moreover, PICC catheter indwelling is a risk factor for bloodstream infections. Conclusion: The nursing staff should adopt targeted and predictive graded-care interventions, including drug prevention and stratified care, to reduce catheter-related thrombosis in patients.

Screening for novel risk factors related to peripherally inserted central catheter-associated complications

2014 ◽  
Vol 9 (8) ◽  
pp. 481-489 ◽  
Author(s):  
Jennifer Moran ◽  
Colleen Y. Colbert ◽  
Juhee Song ◽  
Jane Mathews ◽  
Alejandro C. Arroliga ◽  
...  
Keyword(s):  
Risk Factors ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Novel Risk Factors

scholarly journals The development of a risk score for unplanned removal of peripherally inserted central catheter in newborns

2015 ◽  
Vol 23 (3) ◽  
pp. 475-482 ◽  
Author(s):  
Priscila Costa ◽  
Amélia Fumiko Kimura ◽  
Debra Huffman Brandon ◽  
Eny Dorea Paiva ◽  
Patricia Ponce de Camargo
Keyword(s):  
Risk Factors ◽  
Risk Score ◽  
Neonatal Intensive Care ◽  
Operating Characteristic ◽  
Bivariate Analysis ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Single Lumen ◽  
Double Lumen Catheter ◽  
Lumen Catheter

OBJECTIVE: to develop a risk score for unplanned removal of peripherally inserted central catheter in newborns.METHOD: prospective cohort study conducted in a neonatal intensive care unit with newborn babies who underwent 524 catheter insertions. The clinical characteristics of the newborn, catheter insertion and intravenous therapy were tested as risk factors for the unplanned removal of catheters using bivariate analysis. The risk score was developed using logistic regression. Accuracy was internally validated based on the area under the Receiver Operating Characteristic curve.RESULTS: the risk score was made up of the following risk factors: transient metabolic disorders; previous insertion of catheter; use of a polyurethane double-lumen catheter; infusion of multiple intravenous solutions through a single-lumen catheter; and tip in a noncentral position. Newborns were classified into three categories of risk of unplanned removal: low (0 to 3 points), moderate (4 to 8 points), and high (≥ 9 points). Accuracy was 0.76.CONCLUSION: the adoption of evidence-based preventative strategies based on the classification and risk factors faced by the newborn is recommended to minimize the occurrence of unplanned removals.

scholarly journals Prehospital delay is an important risk factor for mortality in community-acquired bloodstream infection (CA-BSI): a matched case–control study

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e052582
Author(s):  
Martin Holmbom ◽  
Maria Andersson ◽  
Sören Berg ◽  
Dan Eklund ◽  
Pernilla Sobczynski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Bloodstream Infection ◽  
Case Control Study ◽  
Case Control ◽  
Important Risk Factor ◽  
Retrospective Case ◽  
Prehospital Delay ◽  
All Cause Mortality ◽  
Control Study

ObjectivesThe aim of this study was to identify prehospital and early hospital risk factors associated with 30-day mortality in patients with blood culture-confirmed community-acquired bloodstream infection (CA-BSI) in Sweden.MethodsA retrospective case–control study of 1624 patients with CA-BSI (2015–2016), 195 non-survivors satisfying the inclusion criteria were matched 1:1 with 195 survivors for age, gender and microorganism. All forms of contact with a healthcare provider for symptoms of infection within 7 days prior CA-BSI episode were registered. Logistic regression was used to analyse risk factors for 30-day all-cause mortality.ResultsOf the 390 patients, 61% (115 non-survivors and 121 survivors) sought prehospital contact. The median time from first prehospital contact till hospital admission was 13 hours (6–52) for non-survivors and 7 hours (3–24) for survivors (p<0.01). Several risk factors for 30-day all-cause mortality were identified: prehospital delay OR=1.26 (95% CI: 1.07 to 1.47), p<0.01; severity of illness (Sequential Organ Failure Assessment score) OR=1.60 (95% CI: 1.40 to 1.83), p<0.01; comorbidity score (updated Charlson Index) OR=1.13 (95% CI: 1.05 to 1.22), p<0.01 and inadequate empirical antimicrobial therapy OR=3.92 (95% CI: 1.64 to 9.33), p<0.01. In a multivariable model, prehospital delay >24 hours from first contact remained an important risk factor for 30-day all-cause mortality due to CA-BSI OR=6.17 (95% CI: 2.19 to 17.38), p<0.01.ConclusionPrehospital delay and inappropriate empirical antibiotic therapy were found to be important risk factors for 30-day all-cause mortality associated with CA-BSI. Increased awareness and earlier detection of BSI in prehospital and early hospital care is critical for rapid initiation of adequate management and antibiotic treatment.

Peripherally inserted central catheter-related complications in cancer patients: a prospective study of over 50,000 catheter days

2017 ◽  
Vol 18 (2) ◽  
pp. 153-157 ◽  
Author(s):  
Junren Kang ◽  
Wei Chen ◽  
Wenyan Sun ◽  
Ruibin Ge ◽  
Hailong Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Multivariable Analysis ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Multivariable Logistic Regression Analysis ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Multicenter Cohort Study ◽  
Related Factors

Purpose To evaluate incidence and risk factors of peripherally inserted central catheter (PICC)-related complications in cancer patients. Methods A prospective, multicenter, cohort study of cancer patients with PICC insertion was performed from February 1, 2013 to April 24, 2014. All patients were monitored in clinic until PICCs were removed. The primary endpoint was PICC removal due to complications. Patient-, catheter- and insertion-related factors were analyzed in univariable and multivariable logistic regression analysis to identify significant independent risk factors for PICC-related complications. Results There were 477 cancer patients included, for a total of 50,841 catheter-days. Eighty-one patients (17.0%) developed PICC-related complications, with an incidence of 1.59 per 1000 catheter days. Thirty-six (7.5%) PICCs were removed because of complications. The most common complications were skin allergy (4.6%), catheter occlusion (3.4%) and accidental withdrawal (2.3%). Nine (1.9%) patients developed symptomatic upper extremity deep venous thrombosis (UEDVT) and central line associated bloodstream infection (CLABSI) was shown in six (1.3%) PICCs with an infection rate 0.12 per 1000 catheter days. In multivariable analysis, body mass index (BMI) >25 (odds ratio, 2.09; 95% confidence interval, 1.26-3.47, p = 0.004) was shown to be a significant risk factor for PICC complications. Conclusions Cancer patients with BMI greater than 25 were more likely to have PICC complications.

A case of unexpected peripherally inserted central catheter removal from a colorectal cancer patient with cetuximab-induced skin toxicity and contact dermatitis at the peripherally inserted central catheter insertion site: Should we recommend the patient to choose subcutaneous port preferentially?

2020 ◽  
pp. 112972982091088
Author(s):  
Hui Yang ◽  
Yuanyi Rui ◽  
Guorong Wang
Keyword(s):  
Colorectal Cancer ◽  
Contact Dermatitis ◽  
Metastatic Colorectal Cancer ◽  
Cancer Patients ◽  
Insertion Site ◽  
Skin Toxicity ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Catheter Insertion Site ◽  
Colorectal Cancer Patients

Introduction: Obtaining central venous access is one of the most commonly performed procedures in cancer patients. However, there are very limited data to guide clinicians when selecting a device for metastatic colorectal cancer patients who received cetuximab. Case description: A 54-year-old male patient with metastatic colorectal cancer treated with cetuximab plus FOLFIRI used peripherally inserted central catheter as intravenous pathway. After eight cycles, the patient suffered cetuximab-induced grade 2 skin toxicity and grade 3 contact dermatitis at the peripherally inserted central catheter insertion site. Finally, he removed the peripherally inserted central catheter and accepted subcutaneous port instead for 2 years without implantation cutaneous complication. Conclusions: We suggest that metastatic colorectal cancer patients treated with cetuximab should be recommended to choose subcutaneous port preferentially to avoid potential risk of unexpected peripherally inserted central catheter removal due to cetuximab-induced skin toxicity or contact dermatitis. Further clinical practices and researches are needed for more profound evidences for better practical suggestions.

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