scholarly journals Evaluation of Pilot Implementation of Seasonal Malaria Chemoprevention on Morbidity in youngChildren In Northern Sahelian Ghana

2021 ◽  
Author(s):  
Patrick Odum Ansah ◽  
Nana Akosua Ansah ◽  
Keziah Malm ◽  
Denis Awuni ◽  
Nana Peprah ◽  
...  
Keyword(s):  
Northern Region ◽  
Incidence Rates ◽  
Control Area ◽  
World Health ◽  
Northern Ghana ◽  
Wet Season ◽  
Malaria Parasitemia ◽  
Intervention Area ◽  
Seasonal Malaria Chemoprevention ◽  
Pilot Implementation

Abstract Background In Sahelian Africa, the risk of malaria increases with the arrival of the rains, during which most clinical malaria occur particularly in young children. Following successful trials in 2012, the World Health Organization (WHO) recommended the use of seasonal malaria chemoprevention (SMC) in areas where there is a seasonal peak in malaria. This study evaluated the pilot implementation of SMC in Northern Ghana. Methods Fourteen communities each serving as clusters were selected randomly from Lawra District of Upper West Region as intervention area and West Mamprusi District in the Northern Region as the control area all in Ghana. The intervention was undertaken by the National Malaria Control Program using Sulphadoxine Pyrimethamine plus Amodiaquine and standard WHO protocols. Before and after intervention surveys for malaria parasitemia and hemoglobin levels were assessed as well as monitoring of malaria morbidity. Results Incidence rates of severe malaria were 10 and 20 per 1000 person-years follow up in the intervention and comparison areas respectively with P.E of 45% (p = 0.62). For mild malaria, it was 220 and 170 per 1000 person-years in intervention and comparison area respectively with PE of − 25% (p = 0.31). Differences in anemia (Hb < 11.0g/dl) from baseline to end-line was a reduction of 0.16g/dl (p = 0.000) in intervention and an increase of 0.12g/dl (p = 0.002) in the control area. Mean Hb difference between baseline and end-line was a reduction of 0. 24g/dl (p = 0.000) in control and an increase of 0.39g/dl (p = 000) in the intervention area. At the end of the intervention, the proportion of children with asexual parasites reduced by 19% (p = 0.000) in the intervention and increased by 12%(p = 0.000) in the control area. Conclusion The feasibility of SMC in Northern Ghana was demonstrated as evidenced by high study retention, reduction in malaria parasitemia and anemia during the wet season.

scholarly journals Evaluation of pilot implementation of seasonal malaria chemoprevention on morbidity in young children in Northern Sahelian Ghana

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Patrick O. Ansah ◽  
Nana A. Ansah ◽  
Keziah Malm ◽  
Dennis Awuni ◽  
Nana Peprah ◽  
...  
Keyword(s):  
Young Children ◽  
World Health ◽  
Northern Ghana ◽  
Malaria Control Programme ◽  
Malaria Parasitaemia ◽  
Wet Season ◽  
Intervention Participant ◽  
Intervention Area ◽  
Seasonal Malaria Chemoprevention ◽  
Pilot Implementation

Abstract Background In Sahelian Africa, the risk of malaria increases with the arrival of the rains, particularly in young children. Following successful trials, the World Health Organization (WHO) recommended the use of seasonal malaria chemoprevention (SMC) in areas with seasonal peak in malaria cases. This study evaluated the pilot implementation of SMC in Northern Ghana. Methods Fourteen communities each serving as clusters were selected randomly from Lawra District of Upper West Region as intervention area and West Mamprusi District in the Northern Region as the non-intervention area. The intervention was undertaken by the National Malaria Control Programme in collaboration with regional health directorates using sulfadoxine-pyrimethamine plus amodiaquine and standard WHO protocols. Before and after surveys for malaria parasitaemia and haemoglobin levels as well as monitoring for malaria morbidity and mortality were undertaken. Results At the end of the intervention, participant retention was 92.9% (697/731) and 89.5% (634/708) in the intervention and the non-intervention areas, respectively. The proportion of children with asexual parasites reduced by 19% (p = 0.000) in the intervention and increased by 12% (p = 0.000) in the non-intervention area. Incidence rates of severe malaria were 10 and 20 per 1000 person-years follow up in the intervention and comparison areas, respectively with P.E of 45% (p = 0.62). For mild malaria, it was 220 and 170 per 1000 person-years in intervention and comparison area, respectively with PE of - 25% (p = 0.31). The proportion of children with anaemia defined as Hb< 11.0 g/dl reduced from 14.2% (52.8–38.6%) in the intervention area as compared to an increase of 8.1% (54.5% to 62.6) the non-intervention arm, Mean Hb reduced by 0. 24 g/dl (p = 0.000) in the non-intervention area and increased of 0.39 g/dl (p = 000) in the intervention area. Conclusions The feasibility and effectiveness of SMC introduction in Northern Ghana was demonstrated as evidenced by high study retention, reduction in malaria parasitaemia and anaemia during the wet season.

scholarly journals Control trial of porcine cysticercosis in Uganda using a combination of the TSOL18 vaccination and oxfendazole

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Zachary Nsadha ◽  
Chris Rutebarika ◽  
Chrisostom Ayebazibwe ◽  
Bukenya Aloys ◽  
M. Mwanja ◽  
...  
Keyword(s):  
Taenia Solium ◽  
Control Program ◽  
Control Area ◽  
Sub Saharan Africa ◽  
Intermediate Hosts ◽  
Porcine Cysticercosis ◽  
Intervention Area ◽  
Significant Difference ◽  
Sub Saharan ◽  
Village Communities

Abstract Background Neurocysticercosis caused by Taenia solium when the parasite lodges in the central nervous system, is an important cause of human seizures and mortality in sub-Saharan Africa. The parasite is prevalent in many regions of Uganda. Pigs are intermediate hosts for T. solium, and we evaluated a T. solium control program in pigs, involving vaccination of pigs with the TSOL18 vaccine and treatment with oxfendazole. Methods The study was conducted in two districts of Eastern Uganda involving the rural village communities of Bukedea (intervention area) and Kumi (control area) during 2016–2017. Seven hundred and thirty-four households were enrolled in the study. Pigs in the intervention area received intramuscular immunizations with TSOL18 (Cysvax™) and an oral medication with 30 mg/kg oxfendazole (Paranthic™) at approximately 3-monthly intervals for 18 months. Porcine cysticercosis was evaluated by post-mortem examination. At the beginning of the study, 111 pigs were examined. In an interim evaluation in the intervention area, 55 pigs were evaluated 12 months after starting the project. At the end of the study approximately 3 months after the final intervention, 55 pigs from the intervention area and 56 pigs from the control area were evaluated. Results The prevalence of porcine cysticercosis for the two sites was 16.2% at the beginning of the study (17.2% in the intervention area and 15.1% in the control area) with no statistically significant difference (P = 0.759) between the two study sites. Among the 110 animals assessed from the intervention site (55 at the interim evaluation and 55 at the final evaluation), no pig with viable T. solium cysts was found. There was a statistically significant difference between the prevalence at baseline (17.2%) and at the end of the study (0%) in the intervention area (P = 0.001) and a statistically significant difference between the intervention (0%) and control areas (5.4%) (P = 0.041) at the end of the study. Conclusions Three-monthly concurrent vaccination of pigs with the TSOL18 vaccine and medication with oxfendazole eliminated T. solium transmission by the animals involved in the study. Application of vaccination with medication in pigs has the potential to reduce transmission of T. solium in Uganda and other endemic countries.

scholarly journals Climate Variability Since 1970 and Farmers’ Observations in Northern Ghana

2016 ◽  
Vol 5 (2) ◽  
pp. 41 ◽  
Author(s):  
Emmanuel Nyadzi
Keyword(s):  
Climate Change ◽  
Climate Variability ◽  
Water Conservation ◽  
Crop Production ◽  
Meteorological Data ◽  
Northern Region ◽  
Northern Ghana ◽  
Climate Variability And Change ◽  
Urban Centers ◽  
Access To Credit

<p>The study examines how farmers’ observations of climate variability and change correspond with 42 years (1970-2011) meteorological data of temperature and rainfall. It shows how farmers in the Northern Region of Ghana adjust to the changing climate and explore the various obstacles that hinder the implementation of their adaptation strategies. With the help of an extension officer, 200 farmers from 20 communities were randomly selected based on their farming records. Temperatures over the last four decades (1970-2009) increased at a rate of 0.04 (± 0.41) ˚C and 0.3(± 0.13)˚C from 2010-2011 which is consistent to the farmers (82.5%) observations. Rainfall within the districts are characterised by inter-annual and monthly variability. It experienced an increased rate of 0.66 (± 8.30) mm from 1970-2009, which was inconsistent with the farmers (81.5%) observation. It however decreased from 2010-2011 at a huge rate of -22.49 (±15.90) mm which probably was the reason majority of the respondents claim rainfall was decreasing. Only 64.5% of the respondents had adjusted their farming activities because of climate variability and change. They apply fertilizers and pesticides, practice soil and water conservation, and irrigation for communities close to dams. Respondents desire to continue their current adaptation methods but may in the future consider changing crop variety, water-harvesting techniques, change crop production to livestock keeping, and possibly migrate to urban centers. Lack of climate change education, low access to credit and agricultural inputs are some militating factors crippling the farmers’ effort to adapt to climate change.</p>

Changes in crime surrounding an urban home renovation and rebuild programme

Urban Studies ◽  
2021 ◽  
pp. 004209802199514
Author(s):  
Michelle Kondo ◽  
Michelle Degli Esposti ◽  
Jonathan Jay ◽  
Christopher N. Morrison ◽  
Bridget Freisthler ◽  
...  
Keyword(s):  
Social Determinant ◽  
Control Area ◽  
Comparative Case Study ◽  
Synthetic Control ◽  
Healthy Homes ◽  
Children's Hospital ◽  
Health And Wellbeing ◽  
Intervention Area ◽  
Children’S Hospital ◽  
Abandoned Properties

Neighbourhood environments are a known social determinant of health. Vacant and abandoned buildings and lots and poor or hazardous housing conditions, combined with crime and violence, can affect residents’ health and wellbeing. Nationwide Children’s Hospital and its partners launched the Healthy Homes initiative in 2008, which sought to improve nearby residents’ health and wellbeing by rejuvenating vacant and abandoned properties and increasing homeownership in the South Side neighbourhood of Columbus, Ohio. Between 2008 and mid-2019 the initiative funded 273 repairs or renovations in this neighbourhood. We conducted a ZIP-code-level comparative case study of the Healthy Homes housing interventions using synthetic control methodology to evaluate changes in crime rate in the intervention area compared with those in a synthetic control area. While findings were mixed, we found some evidence of reduced thefts in the Healthy Homes area, relative to its synthetic control. This initiative to repair, rebuild and increase ownership of housing has the potential to reduce crime rates for neighbours of the Nationwide Children’s Hospital.

Physico-chemical and Biological Properties of Groundwater Quality in Rural Settlement, Nadi, Fiji

2021 ◽  
Vol 18 (1) ◽  
pp. 1-6
Author(s):  
Roselyn Naidu ◽  
Lionel Joseph ◽  
Syed Sauban Ghani
Keyword(s):  
Water Quality ◽  
Drinking Water ◽  
Biological Properties ◽  
Drinking Water Quality ◽  
World Health ◽  
Wet Season ◽  
Potential Health ◽  
Drinking Water Contamination ◽  
Contamination Levels ◽  
Health Organization

The current study investigated drinking water quality of samples taken from Arolevu village, a locality situated in Nadi, Fiji. The groundwater samples were collected and subjected to a comprehensive physicochemical and biological analysis. The analysis for the drinking water sample was conducted seasonally, six times a year, that is, three for the dry season and three for the wet season. The results retrieved from the analysis were compared to its maximum contamination levels (MCLs) based on the health-based guidelines provided by the World Health Organization (WHO). The WHO standards were used as an attribute to determine the sources of contaminants likely to be present at the study site. A degradation trend in drinking water quality in the context of climate change may lead to potential health impacts. Hence, it is important to understand seasonal variations in drinking water quality. A proper understanding of the drinking water quality through seasonal water analysis for nitrate, nitrite, potassium, calcium, magnesium and chlorine content as well as its microbiological presence to reduce preventable risks such as using calculated amounts of fertilisers and upgrading the sewerage system to alleviate drinking water contamination is devised through this study.

Evaluation of a Promotional Strategy to Increase Bicycle Helmet Use by Children

PEDIATRICS ◽  
1993 ◽  
Vol 91 (4) ◽  
pp. 772-777
Author(s):  
Patricia C. Parkin ◽  
Laura J. Spence ◽  
Xiaohan Hu ◽  
Katherine E. Kranz ◽  
Linda G. Shortt ◽  
...  
Keyword(s):  
Low Income ◽  
Head Injuries ◽  
Control Area ◽  
High Income ◽  
Bicycle Helmet ◽  
Helmet Use ◽  
Modest Increase ◽  
Promotional Strategy ◽  
Intervention Area ◽  
Low Income Families

Bicycle-related head injuries are an important cause of death and disability, despite the availability of helmets. The objective of this study was to evaluate the effectiveness of a school-based bicycle helmet promotion program in increasing helmet use by children while controlling for secular trends. Two high-income and two low-income schools in an urban Canadian community were selected to receive a bicycle helmet promotion intervention, with the remaining 18 schools serving as controls. Approximately 1800 observations of bicycling children were made at randomly selected observational sites 2 to 5 months after the intervention to assess changes in behavior. Helmet use at all observation sites tripled from 3.4% (1990, preintervention) to 16% (1991, postintervention). In the high-income intervention area, observed helmet use rose dramatically from 4% to 36% in contrast to the more modest increase in the high-income control area from 4% to 15%. In the low-income intervention area, there was a modest increase from 1% to 7%, but it did not differ from the increase in the low-income control area from 3% to 13%. The program was highly successful in children of high-income families but not in children of low-income families. Developing strategies for low-income families remains a priority.

scholarly journals Development, validation, and pilot implementation of the minimum datasheet for a domestic violence registry system: The case of a developing country

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261460
Author(s):  
Shabnam Iezadi ◽  
Kamal Gholipour ◽  
Ahmad Khanijahani ◽  
Mahasti Alizadeh ◽  
Bahram Samadirad ◽  
...  
Keyword(s):  
Domestic Violence ◽  
Sexual Violence ◽  
Rural Areas ◽  
Content Validity ◽  
Past History ◽  
The Elderly ◽  
World Health ◽  
Registry System ◽  
History Of ◽  
Pilot Implementation

Background Domestic violence (DV) is a universal issue and an important public health priority. Establishing a DV Registry System (DVRS) can help to systematically integrate data from several sources and provide valid and reliable information on the scope and severity of harms. The main objective of this study was to develop, validate, and pilot-test a minimum datasheet for a DVRS to register DV victims in medical facilities. Materials and methods This study was conducted in two main phases. Phase one includes developing the datasheet for registration of DV in the DVRS. In phase two, the datasheet designed in the previous step was used in a pilot implementation of the DVRS for 12 months to find practical challenges. The preliminary datasheet was first developed using information on similar registry programs and guidelines of the World Health Organization (WHO) and then reviewed by four expert panels. Through a two-round Delphi technique, experts evaluated the instrument using the Content Validity Index (CVI) and Content Validity Ratio (CVR). The consistency of the responses was evaluated by test-retest analysis. Finally, two physicians in two forensic medical clinics registered the victims of physical and/or sexual violence perpetrated by a family member. Results Preliminary datasheet consisted of 31 items. In the first round of Delphi, fifteen items had good content validity (I-CVI and CVR) and were kept, and seven items were moved to the next round. Also, in the first round of Delphi, experts suggested adding three items, including history of the violence, custody of the child, and custody of the elderly. All items evaluated in the second round were kept due to good CVR and CVI scores. As a result of Test-retest correlation coefficients for self-reprted items, two items including perpetrator’s alcohol and drug use status were excluded (r(30) = +.43, and +.38, p< .01, two-tailed, respectively). Finally, 24 items were included in the datasheet including 15 items for individuals’ characteristics (victims’ characteristics and perpetrators’ characteristics), eight items for incidents’ characteristics, and one item for past history of violence experience. A total of 369 cases were registered from September 23, 2019, to July 21, 2020. The majority of the reported cases were female (82%) and were 19–40 years old. No physical and/or sexual violence was reported from rural areas, which calls upon researchers to explore how services for detecting and treating the victims can be made accessible to these areas. Conclusion DVRS can show trends in DV by age, sex, the context of the violence, and incidence characteristics at every point in time. This is particularly valuable in planning and prioritizing research areas and interventions for DV prevention. Additionally, DVRS can be linked to other disease registry programs which can contribute to continuity and coordination of care, and major research in the future. Although a DVRS can be a promising initiative in identifying the areas in need of urgent interventions, there is no guarantee for its proper implementation due to limited resources and other challenges.

scholarly journals Trends in tuberculosis incidence rates in the Region of Sousse (Tunisia) from 1992 to 2016

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J Sahli ◽  
M Mellouli ◽  
M Limam ◽  
M El Ghardallou ◽  
A Mtiraoui ◽  
...  
Keyword(s):  
Current Trend ◽  
National Level ◽  
Incidence Rates ◽  
World Health ◽  
Epidemiological Surveillance ◽  
Tuberculosis Control ◽  
Tuberculosis Incidence ◽  
Significant Downward Trend ◽  
Development Goals ◽  
Health Organization

Abstract Introduction In 1993, the World Health Organization declared that tuberculosis is a public health emergency of global concern. All efforts were made in accordance with the Millennium Development Goals (MDGs) to reduce the burden of Tuberculosis. The MDG framework built into national priorities and development strategies has, in fact, strengthened epidemiological surveillance and the use of reliable data to make decisions based on objective data. These data are essential for planning, managing the activities of the National Tuberculosis program, monitoring and ongoing evaluation of its performance. In this context, we conducted this study to trace the trend of Tuberculosis incidence rate recorded in the Sousse Region between 1992 and 2016. Methods This is a longitudinal study of the registered data of tuberculosis cases in Sousse between 1992 and 2016. For the trend analysis the software JOINPOINT version 4.5.0.1 was used. This software offers the closest possible regression model of the different points and gives an annual percentage change (APC) with a 95% confidence interval. Results The highest TB incidence rates was recorded in 1993 (85.66 cases per 100 000 inhabitants). Between 1992 and 1997, there was a significant downward trend of TB incidence (APC = -23.2; 95% CI [-28.8, 1]). Between 1997 and 2004 the trend was stable. Between 2004 and 2016, there was a significant upward trend (APC = 8.3; 95% CI: [4.3, 12.4]). Conclusions At the national level, between 1992 and 2002, tuberculosis experienced a fall in incidence rates, as a result of an improvement in the socio-economic level and the organization of tuberculosis control. Since 2004, the trend has been rising. Increased tuberculosis control is advocated to end tuberculosis by 2030 in line with sustainable development goals. Key messages After a significant decrease, the tuberculosis incidence has increased significantly since 2004. The tuberculosis prevention efforts should be intensified to reverse the current trend.

scholarly journals Spatial variability of shallow groundwater level in the Northern Kathmandu Valley

2018 ◽  
Vol 55 (1) ◽  
pp. 45-54
Author(s):  
Manish Shrestha ◽  
Naresh Kazi Tamrakar
Keyword(s):  
Groundwater Level ◽  
Shallow Groundwater ◽  
Soil Surface ◽  
Northern Region ◽  
Dry Season ◽  
Kathmandu Valley ◽  
Wet Season ◽  
Geological Material ◽  
Groundwater Levels ◽  
Shallow Groundwater Level

Groundwater is the water which is present in pore spaces and in the fractures of the geological materials beneath earth surface. Water is incompressible substance and presence of small amount of water in geological material modifies the behavior of geological material under stresses. Determination of engineering behavior of the geological material is almost impossible skipping the role of water. The objective of this study was to map and evaluate shallow groundwater level of the northern Kathmandu Valley covering main rivers such as the Bagmati River, Bishnumati River, Dhobi Khola and the Manahara Khola. These rivers flow from the North to the South across the sand rich sediment zone. Static groundwater levels of 239 wells were measured from different locations of the study area in April/March 2017 (Dry Season) and in August 2017 (Wet Season). Shallow groundwater level was measured from soil surface to water level using well water depth logger (Qin and Li, 1998). The result showed that groundwater level ranged from 0.6 m to 12.5 m in dry season and 0.1 m to 13 m in wet season. The groundwater level increased by average of 34.68% (n = 235) as compared to that in dry season. Increase in the groundwater level suggests recharge of groundwater in wet season of the study area. The flow pattern of groundwater levels from the study shows flow of shallow groundwater towards the major rivers of that particular river watershed. As a consequence, seepage flow and piping erosion is likely along the riverbank slopes. Increase in recharge of groundwater during wet season exhibits that the northern region of the Kathmandu Valley is potential for groundwater recharge and can be used to manage water for the dry period.

Nitrate pollution in groundwater and strategies to reduce pollution

2002 ◽  
Vol 45 (9) ◽  
pp. 29-35 ◽  
Author(s):  
R.K. Shrestha ◽  
J.K. Ladah
Keyword(s):  
Cropping System ◽  
Sweet Pepper ◽  
World Health ◽  
Wet Season ◽  
Tropical Ecosystem ◽  
Mineral N ◽  
Use Efficiency ◽  
Low Levels ◽  
Indigofera Tinctoria ◽  
N Use

The input-intensive rainfed tropical ecosystem, where wet season (WS) rice (Oriza sativa L.) – dry season (DS) diversified high-value upland crops like vegetables predominate, has resulted in a problem of a large leakage of N into the environment, thereby polluting the water. Excessive use of N fertilizer in high-value crops grown in DS is economically motivated. Out of twenty water sources evaluated in a watershed with a total area of 265 ha located in Magnuang, Ilocos Norte, Philippines, twelve had near or above the World Health Organization’s (WHO) NO3-N limit for drinking water of 10 ppm. Soil mineral N (upper 100 cm) observed in seven rice-sweet pepper (Capsicum annuum L.) farmers’ fields ranged from 111 to 694 kg ha-1 which decreased by 10 to 68% in plots with dry-to-wet (DTW) crops like indigo, indigo+mungo and corn. In fallow plots where mineral N was either maintained or increased, it showed movement to lower soil profiles demonstrating NO3 leaching without a crop. On average, maize (Zea mays L.) captured 176 kg N ha-1 and indigo (Indigofera tinctoria L.) 194 kg N ha-1. In both fallow and planted plots, mineral N declined to low levels at 100% water-filled pore spaces (WFPS) before rice transplanting. A strategy for including indigo plus maize as a N-catch crop is proposed to decrease NO3 leaching and maximize N use efficiency in a rice-sweet pepper cropping system.

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