scholarly journals The Impact Factor of Colon Polyp

2021 ◽  
Author(s):  
Zheng Zhou ◽  
Guangming Wang
Keyword(s):  
Helicobacter Pylori ◽  
Impact Factor ◽  
Recurrence Rate ◽  
Infection Rate ◽  
Colonic Polyp ◽  
Helicobacter Pylori Infection ◽  
Control Group ◽  
Significant Difference ◽  
The Impact ◽  
The Relationship

Abstract Objective: To evaluate the relationship between Helicobacter pylori and colonic polyp.Methods: The clinical data of 850 patients who underwent both colonoscopy and Helicobacter pylori check were collected in our hospital from January 2018 year to January 2019 year. Patients were divided into polyp group and control group. To analyze the helicobacter pylori infection of two groups, and the relationship among helicobacter pylori infection, eradication treatment and recurrence of colonic polyp. Further to analyze the impact factor of the recurrence of colonic polyp.Results: There were no significant difference in sex and age aspects of two groups. Through SPSS software analysis, the infection rate of helicobater pylori was higher in polyp group than in control group. The recurrence rate of helicobacter pylori positive patients were more higher than helicobacter pylori negative patients. The recurrence rate of helicobacter pylori eradication group was lower than helicobacter pylori no eradication group. the impact factor of the recurrence of colonic polyp include helicobacter pylori infection, pathological type of polyp and the number of polyps.Conclusion: The helicobacter pylori infection rate of colonic polyp group were more higher. The impact factor of colonic polyp recurrence include helicobacter pylori infection, pathological types of polyp and polyp number.

Relationship between Helicobacter pylori and development of hepatocellular carcinoma: A systematic review and meta-analysis.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 4091-4091
Author(s):  
Samragnyi Madala ◽  
Kira MacDougall ◽  
Balarama Krishna Surapaneni ◽  
Robin Park ◽  
Anup Kasi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Helicobacter Pylori ◽  
Causal Relationship ◽  
Subgroup Analysis ◽  
Meta Analysis ◽  
Control Group ◽  
Significant Difference ◽  
H Pylori ◽  
The Relationship

4091 Background: The relationship between Helicobacter pylori (H.pylori) and hepatocellular carcinoma (HCC) was first proposed in 1994. Since then, several studies have been performed to explore the association. The role of Hepatitis C (HCV) viruses coexisting with H.pylori in causing HCC was also studied. With the emergence of data in this regard, a causal relationship has been postulated, but not confirmed, and hence the relationship remains controversial. Our meta-analysis aims to summarize the research on this topic and investigate if there exists a relationship between H. pylori infection and the development of HCC and if the presence of HCV along with H.pylori plays a role in liver carcinogenesis. Methods: Following PRISMA guidelines, we performed a systematic review of all relevant studies published in the literature using keywords “Helicobacter pylori” and “Hepatocellular carcinoma” on major literature databases, including PubMed, EMBASE, Web of Science, and Cochrane controlled trials register. A total of 656 studies were identified between 1994 to March 2020, out of which 26 studies qualified under our selection criteria. Patients positive for HCC are included as cases and patients that did not have HCC under control group. In both groups, H.pylori positive patients and their HCV status, was identified. Results: Out of the 26 studies included in the final analysis, the prevalence of H. pylori infection was 64.78% (561 of 866) amongst HCC cases and 47.92% (1718 of 3585) in the non-HCC control group. The summary odds ratio for the association of H. pylori infection with the risk for HCC using the random-effects model was determined to be 4.75 (95% CI, 3.06-7.37), I²=63%. Subgroup analysis to determine the odds of developing HCC in the presence of H.pylori and HCV coinfection, was 13.97 (95% CI, 3.94-49.61), I²=81%. Whereas, the odds of developing HCC in the presence of only HCV without H.pylori was found to be 2.21 (0.70-6.94), I²=79. Subgroup analysis by study design showed no significant difference between the study groups (P= 0.5705). Conclusions: Our meta-analysis showed a positive association between H. pylori infection and the development of HCC. It showed a significantly higher risk of developing HCC in the presence of HCV infection along with H.pylori. Further prospective cohort studies are needed to prove the causal relationship, especially in cases of Hepatitis B, C coinfection, and cirrhotic patients.[Table: see text]

scholarly journals The Impact of Early Dressing Removal on the Tunneled Central Venous Catheters

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 93s-93s
Author(s):  
G. Ammar
Keyword(s):  
Infection Rate ◽  
Central Venous Catheters ◽  
Control Group ◽  
Site Infection ◽  
Exit Site ◽  
Central Venous ◽  
Exit Site Infection ◽  
Significant Difference ◽  
The Impact ◽  
Interventional Group

Background: There were many studies compared between different types of dressing such as chlorhexidine gluconate gel (CHG), (CHG) disc, gauze dressing and transparent dressing regarding its intact to the skin, infection rate and patients satisfaction. However, there was few studies regarding the impact of removing the dressing on the occurrence of exit site infection of tunneled central venous catheters. Aim: The objective of the current study was to evaluate the impact of early central venous catheter (CVC) dressing removal of the well-healed exit site infections. Methods: It was a quasi-experiment pilot study conducted over 15 months duration in a specialized oncology center. All adult patients who had newly inserted tunneled central venous catheters (CVC) in place were recruited. Patients were distributed to control and experimental group based on first come first served. Patients in the control group (n=8) received the standard protocol of applying (CVC) dressing, while patients in the interventional group (n=8) received the protocol of no dressing. Results: There was no significant difference in the infection rate between the two groups ( P = 1), so that, a total of two cases had developed catheter-related bloodstream infection (CLABSI), one in the control group and the other in the interventional group. Moreover, one patient in the interventional group had developed exit site infection. However, patients with no dressing protocol (interventional group) perceived an improvement in their quality of life and they were satisfied with this protocol. Conclusion: Applying no dressing protocol to a well-healed exit site CVCs showed encouraging results in terms of exit site and bloodstream infections. That is to say; it did not predispose patients to increased risk of infections. Furthermore, patients with no dressing protocol feel more comfortable in their lifestyle.

scholarly journals Experimental Study of the Effect of Helicobacter pylori Infection on Barrett Esophagus and Its Correlation with Immune Function

2020 ◽  
Vol 13 (6) ◽  
Author(s):  
Jing Zhang ◽  
Xiao-Ping Tan ◽  
Xin-Zhang Sun ◽  
Qing Zhang
Keyword(s):  
Helicobacter Pylori ◽  
Immune Function ◽  
Lower Esophageal Sphincter Pressure ◽  
Helicobacter Pylori Infection ◽  
Barrett Esophagus ◽  
Control Group ◽  
Sphincter Pressure ◽  
Esophageal Function ◽  
H Pylori ◽  
The Relationship

Background: Helicobacter pylori is an important pathogen in the upper digestive tract. It is of great significance to properly understand the risk factors for the transformation of Barrett esophagus into esophageal carcinoma. However, the relationship between H. pylori and gastroesophageal reflux disease (GERD) and Barrett esophagus remains controversial, and the correlation with immune function has been rarely reported. Objectives: This study investigated the effect of H. pylori infection on Barrett esophagus and its correlation with immune function. Methods: We recruited 40 patients with Barrett esophagus (Barrett esophagus group) and 40 patients with GERD (GERD group). In addition, 40 healthy controls were selected for the control group. Esophageal function and its correlation with immune function were measured in each group. Results: The positivity rate of H. pylori (P < 0.05) and sphincter pressure were lower in both Barrett esophagus and GERD groups than in the control group, while the levels of PGI, PGII, PGI/II, and G-17 were higher (P < 0.05). The levels of CD3+, CD4+, and CD4+/CD8+ were lower in the Barrett esophagus group than in the GERD group, but they were negatively correlated (P < 0.05) with H. pylori infection. The level of CD8+ was higher in the Barrett esophagus group, and it was positively correlated (P < 0.05) with H. pylori infection. Conclusions: Helicobacter pylori infection may protect against Barrett esophagus by reducing gastric acid secretion and increasing lower esophageal sphincter pressure. Besides, it has a certain correlation with immune function.

A Study of the Relationship between Helicobacter pylori and Recurrent Aphthous Stomatitis Using a Urea Breath Test

2009 ◽  
Vol 10 (1) ◽  
pp. 9-16 ◽  
Author(s):  
Maryam Baharvand ◽  
Ziba Maleki ◽  
Kaveh Alavi ◽  
Ali Akbar Sayyari ◽  
Leila Sayyari
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
Urea Breath Test ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Control Group ◽  
Peptic Ulcers ◽  
Significant Difference ◽  
H Pylori ◽  
The Relationship

Abstract Aim Helicobacter pylori (H. pylori) is one of the most common, well-known pathogenic agents in the development of peptic ulcers. Some investigators have shown a relationship between H. pylori and recurrent aphthous stomatitis (RAS). However, this relationship is controversial. The aim of this study was to determine the association between H. pylori and RAS using the urea breath test (UBT). Methods and Materials Forty-three patients with RAS and 44 non-RAS controls were evaluated. There were no differences in gender or age in the two groups. The UBT was used to detect H. pylori infection. Data were analyzed using the Chi Square Test. Results Sixteen individuals in the RAS patients (37.2%) and 14 individuals in the control group (31.8%) had a positive breath test. The difference was not considered statistically significant (p=0.597). Conclusion In the present study no statistically significant difference was found between frequency of a positive UBT in the RAS patients and the control group. Clinical Significance Since the probability of a positive test was higher in the more severe cases this factor needs to be considered in the diagnosis and treatment of RAS. Citation Maleki Z, Sayyari AA, Alvavi K, Sayyari L, Baharvand M. A Study on the Relationship between Helicobacter pylori and Recurrent Aphthous Stomatitis Using a Urea Breath Test. J Contemp Dent Pract 2009 January; (10)1:009-016.

scholarly journals Association between Helicobacter pylori infection and primary open-angle glaucoma

2019 ◽  
Vol 12 (1) ◽  
pp. 25-28
Author(s):  
Sayaka Sultana ◽  
Nazneen Khan ◽  
Chonchol Kumar Ghosh ◽  
Ahmed Abu Saleh ◽  
Md. Shafiqul Islam
Keyword(s):  
Helicobacter Pylori ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Helicobacter Pylori Infection ◽  
Control Group ◽  
Case Group ◽  
Open Angle ◽  
Significant Difference ◽  
13C Urea Breath Test ◽  
H Pylori

The pathological processes of primary open-angle glaucoma is unknown. Several studies show the relation between Helicobacter pylori infection and primary open-angle glaucoma. The purpose of this study was to assess the association between H. pylori infection and primary open-angle glaucoma. Forty patients of diagnosed primary open-angle glaucoma were selected as case and 40 participants without primary open-angle glaucoma were selected as control as per inclusion and exclusion criteria. Complete clinical evaluation including history, physical examination, relevant ocular examinations and laboratory investigations were performed. Serologic evidence of H. pylori infection was found in 75% of patients with primary open-angle glaucoma and 30% of patients without primary open-angle glaucoma which achieved statistically significant difference (p=0.000, OR=7.00 and CI 95% =2.61-18.74). 13C urea breath test was positive in 70% in case group and 37.5% in control group which also achieved statistically significant difference  (p=0.003, OR=3.89 and CI 95% =1.53-9.87). The findings revealed significant association between H. pylori infection and primary open-angle glaucoma.  

scholarly journals Characteristics of gastric and duodenal mucosa in patients with primary biliary cholangitis

2019 ◽  
Vol 76 (6) ◽  
pp. 593-597
Author(s):  
Dragan Popovic ◽  
Sanja Zgradic ◽  
Sanja Dragasevic ◽  
Simon Zec ◽  
Marijan Micev ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Atrophic Gastritis ◽  
Duodenal Mucosa ◽  
Helicobacter Pylori Infection ◽  
Control Group ◽  
Primary Biliary Cholangitis ◽  
Immune Mediated ◽  
Group Methods ◽  
Significant Difference ◽  
Gluten Sensitive Enteropathy

Background/Aim. Primary biliary cholangitis (PBC) is an immune-mediated chronic cholestatic disease of liver, with a slow progression. The aim of our study was to determine the correlation of PBC, atrophic gastritis (AG) and gluten-sensitive enteropathy (GSE), to identify the macroscopic and histopathological modifications of gastric and duodenal mucosa which occur in PBC and to analyze the frequency of these changes compared to a control group. Methods. This study included 50 patients with PBC and 46 control subjects with the dyspeptic symptoms, without liver disease. All of the examined subjects underwent esophagogastroduodenoscopy. Macroscopic and histopathological findings of the gastric and duodenal mucosal samples were recorded and analyzed. Results. There was no statistically significant association between the PBC and AG, or between the PBC and Helicobacter pylori infection. There was a highly significant difference in the frequency of Helicobacter pylori infection and the presence of GSE in the patients in the control group compared to those with PBC. Conclusions. The patients with PBC are at a lower risk for Helicobacter pylori infectionand atrophic gastritis. Testing for GSE in the PBC patients may be beneficial, considering the higher incidence of GSE amongst these patients. GSE represents a risk factor for the presence of PBC and the patients with GSE are nearly four times more likely to have PBC.

The impact of Helicobacter pylori on the presence of Barrett's esophagus in Azerbaijan, a high-prevalence area of infection

2019 ◽  
Vol 32 (11) ◽  
Author(s):  
S Aghayeva ◽  
K C Mara ◽  
D A Katzka
Keyword(s):  
Helicobacter Pylori ◽  
Intestinal Metaplasia ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Erosive Esophagitis ◽  
Control Group ◽  
Significant Difference ◽  
High Prevalence ◽  
H Pylori ◽  
The Impact

SUMMARY There is a strong evidence that Helicobacter pylori infection is inversely associated with Barrett's esophagus. In a high-prevalence region of H. pylori, low rates of esophageal cancer and its precursor BE may indicate its preventive effect. The aim of this study is to determine the impact of H. pylori on characteristics of Barrett's esophagus. A total of 3317 outpatient upper endoscopy reports from 2013 to 2015 from an urban center in Azerbaijan from all patients with dyspepsia were retrospectively analyzed for patients with Barrett's esophagus. This was matched in a 1:2 ratio to age and gender matched control patients without Barrett's esophagus. The prevalence of H. pylori on Barrett's esophagus and the randomly selected control group were compared. There were 83 patients with BE and 167 control group cases. Biopsy-proven BE was diagnosed in 83 patients: 39 (47%) females, with mean age 43.1 ± 13.3 years. Of these, 13 (15.7%) had long segment and 70 (84.3%) had short segment Barrett's esophagus. A control group included 167 patients: 78 (46.7%) females, with mean age (45.8 ± 13.9). All patients were Caucasians. The rates of gastric inflammation, the presence of atrophy, and intestinal metaplasia in gastric specimens did not differ in patients versus controls. The prevalence of H. pylori was determined as 63.2% in male and 61.5 in female groups (odd ratio (OR) = 0.99 95%CI 0.97, 1.01; P = 0.22). Inflammation of gastric mucosa was strongly associated with the infection (67% vs. 33%; OR = 4.46 95% CI: 2.01, 9.92, P &lt; 0.001). Atrophy was noted in majority of H. pylori-positive cases (OR = 1.43, 95% CI: 0.36, 5.65; P = 0.61). Gastric intestinal metaplasia was observed in 55.6% of H. pylori-positive patients and in 44.4% of negative individuals (OR = 0.74, 95% CI: 0.28, 1.94; P = 0.54). There was not a significant difference in the prevalence of HP in BE and control groups; 63.9% were positive for infection in BE cases and 61.7% of controls (OR = 1.10, 95% CI: 0.64, 1.90; P = 0.74). We found that neither presence of erosive esophagitis, length of BE nor dysplasia (45.5% of H. pylori-positive group, whereas 54.5%) was associated with the presence of the H. pylori infection (Table 1). In a predominantly Caucasian nation with a high prevalence of H. pylori gastritis, the presence of H. pylori was not inversely associated with the presence of Barrett's esophagus. These data challenge the mechanistic implications of this association.

scholarly journals An Opportunistic infection during stay home period in COVID 19 outbreak; Helicobacter Pylori

2021 ◽  
Vol 8 (4) ◽  
pp. 271-274
Author(s):  
Mesut Aydin ◽  
Serhat Ozer ◽  
Yaren Dirik ◽  
Ahmet Cumhur Dulger
Keyword(s):  
Helicobacter Pylori ◽  
Risk Factor ◽  
Gastric Biopsy ◽  
Helicobacter Pylori Infection ◽  
Control Group ◽  
Established Risk Factor ◽  
Biopsy Specimens ◽  
The Impact ◽  
Upper Gastrointestinal ◽  
At Home

Objective: Helicobacter pylori infection is a well-established risk factor for gastric cancer, which is more common in developing countries where poor sanitation and domestic overcrowding are common. We tried to analyze the impact of the pandemic on Helicobacter pylori infection during COVID 19 related curfew and stay-at-home order. Material and Methods: Between 1-30 June 2020 (during stay-at-home order), a total of 172 dyspeptic patients who underwent upper gastrointestinal system endoscopy at our institution following stay-at-home order during COVID pandemic were included in this study along with a control group covering 192 dyspeptic patients who underwent endoscopy between 1-20 June 2019. Results: When we analyzed gastric biopsy specimens, those who faced stay-at-home order had similar rates of intestinal metaplasia (22% versus 29%; p=0.15) and atrophic gastritis (24% versus 29%; p= 0.396) compared to recent year's data. On the other hand, the rate of H.pylori infection was higher compared to pre-COVID period (59% vs. 46%, p<0.05). Conclusion: Domestic overcrowding during COVID 19 related stay-at-home order is a risk factor for H.pylori infection.

scholarly journals The Relationship Between Infertility and Infection with Clarithromycin Resistant Strain of Helicobacter Pylori in Iraq

2020 ◽  
pp. 1874-1879
Author(s):  
Shiamaa G. Abid ◽  
Rana S. Aboud
Keyword(s):  
Helicobacter Pylori ◽  
Seminal Fluid ◽  
Control Group ◽  
Control Groups ◽  
Significant Difference ◽  
Polymerase Chain ◽  
H Pylori ◽  
And Control ◽  
The Relationship ◽  
Infertile Patients

The relationship between infertility and Helicobacter pylori infection was investigated; samples from thirty-five infertile patients (aged 20-49 years) were collected from Kamal Al-Samaraei hospital , Baghdad, Iraq during the period from the first of February until April 2018. These patients were compared with 10 apparently fertile individuals who served as a control. The study was carried out to detect the DNA of H.pylori in both serum and seminal fluid of male infertile patients and for the control group by Real-Time Polymerase Chain Reaction (RT-PCR) technique. The results revealed that there was a significant difference (P<0.01) in the detection of DNA of H.pylori between patients and control groups. thereby the percentage level of H.pylori DNA in serum was 80% and in the seminal fluid was 0 %. As a result, we strongly suggest that the infection with H. pylori plays an important role in male infertility.

scholarly journals Evaluation of the Relationship Between Childhood Asthma and Helicobacter pylori Sero-Prevalence

2019 ◽  
Author(s):  
Rasoul Nasiri ◽  
Pedram Ataee ◽  
Azad Abdi ◽  
Ghobad Moradi ◽  
Borhan Moradveisi ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Cigarette Smoke ◽  
Childhood Asthma ◽  
Control Group ◽  
Case Group ◽  
Significant Difference ◽  
History Of ◽  
H Pylori ◽  
And Control ◽  
The Relationship

In recent years, the prevalence of asthma and allergic rhinitis has increased in developed countries. Helicobacter pylori (H. pylori) infection can exacerbate asthma. The purpose of this study was to investigate the relationship between asthma and H. pylori seroprevalence in children. In this cross-sectional study, 100 children aged 5-15 years hospitalized in Besat hospital in Sanandaj were investigated from 2015 to 2016. Fifty children with asthma were considered as the case group and 50 non-asthmatic children as the control group. The questionnaires were completed, including demographic information, history of asthma, exposure to cigarette smoke, and family history of gastric and duodenal ulcers. Blood samples were collected from the children, and the serum level of specific antibodies (IgG) of H. pylori was measured. There were 42 and 31 boys in the case and control group, respectively. The mean age in the case group was 8.12±2.29 and in the control group was 8.9±2.52 years. In the case group, 48% were exposed to cigarette smoke and in the control group, 18%. There was a statistically significant difference between the groups in terms of gender and exposure to cigarette smoke (P=0.001 and P=0.013, respectively). There was no significant difference between the case and control groups in terms of H. pylori seroprevalence. (P=0.211). There was no significant association between asthma and H. pylori seroprevalence. (P=0.22). According to our study, there no correlation between childhood asthma and H. pylori seroprevalence. © 2019 Tehran University of Medical Sciences. All rights reserved. Acta Med Iran 2019;57(5):299-302.

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