scholarly journals Application of Three-Dimensional Transesophageal Echocardiography in Preoperative Evaluation of Transcatheter Aortic Valve Replacement

2020 ◽  
Author(s):  
Peng Ding ◽  
Chennian Xu ◽  
Yang Liu ◽  
Jiayou Tang ◽  
Ping Jin ◽  
...  
Keyword(s):  
Roc Curve ◽  
Aortic Root ◽  
Preoperative Evaluation ◽  
Rank Correlation ◽  
Left Ventricular ◽  
Aortic Annulus ◽  
Spearman Rank Correlation ◽  
Aortic Sinus ◽  
Spearman Rank ◽  
Annulus Diameter

Abstract BackgroundAnalysing the accuracy of 3D-TEE in preoperative evaluation of TAVR compared with CT when the error led by inconsistent software and method has been eliminated and the representativeness of sample has been improved, and exploring the influence of aortic root calcification on the accuracy of 3D-TEE in aortic annulus evaluations.MethodsPart I: 45 of 233 patients who underwent TAVR in the department of cardiovascular surgery in Xijing hospital from January 2016 to August 2019 were retrospectively studied. Mimics and multiplanar reconstruction method were used for evaluation based on 3D-TEE and CT. Annulus diameter - area derived (Da), annulus diameter - perimeter derived (Dp), annulus mean diameter, the left ventricular outflow tract (LVOT) diameter-Dp, the sinus tube junction (STJ) diameter-Dp and aortic sinus diameter were compared and analyzed. Part ii: 31 of 233 patients whose 3D-TEE and CT data were well preserved and in the required format were included. HU450 and HU850 were used as indicators to measure the severity of calcification, and spearman rank correlation and ROC curve was used to analyze the correlation between aortic root calcification and accuracy of 3D-TEE in aortic annulus measurement.ResultsThe measurement results based on 3D-TEE were significantly lower than those of CT (p<0.05), except for the STJ diameter-Dp in diastole (p=0.11). The correlation coefficient of the two groups was 0.699 ~ 0.954 (p < 0.01), which also indicated a significant correlation between the two groups.Bland-Altman plot showed that the ordinate values were mostly within the 95% consistency limit, the consistency of the two groups was good. By establishing the linear regression equation, the two groups can be inferred from each other. Spearman rank correlation analysis and ROC curve analysis showing that the influence of aortic calcification on the accuracy of 3D-TEE annulus evaluation was limited.ConclusionsWhlie evaluation based on 3D-TEE underestimated the results, we can deduce CT results from 3D-TEE as they obtain considerable correlation and consistency. Calcification in the aortic sinus did not affect the accuracy of 3D-TEE annulus evaluation.Trial registrationName: Surgery and Transcatheter Intervention for Structural Heart DiseasesNumber: NCT02917980URL : https://clinicaltrials.gov/ct2/results?term=NCT02917980

scholarly journals Application of three-dimensional transesophageal echocardiography in preoperative evaluation of transcatheter aortic valve replacement

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Peng Ding ◽  
Chennian Xu ◽  
Yang Liu ◽  
Xin Meng ◽  
Ping Jin ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Linear Regression ◽  
Aortic Valve Replacement ◽  
Aortic Root ◽  
Transcatheter Aortic Valve Replacement ◽  
Preoperative Evaluation ◽  
Rank Correlation ◽  
Spearman Rank Correlation ◽  
Spearman Rank ◽  
Transcatheter Aortic Valve

Abstract Background Our goal was to determine the accuracy of 3-dimensional transesophageal echocardiography (3D-TEE) compared with that of computed tomography (CT) in the preoperative evaluation for transcatheter aortic valve replacement (TAVR) when the errors caused by inconsistent software and method have been eliminated and the representativeness of the sample has been improved. We also investigated the influence of aortic root calcification on the accuracy of 3D-TEE in aortic annulus evaluations. Methods Part I: 45 of 233 patients who underwent TAVR in the department of cardiovascular surgery at the Xijing hospital from January 2016 to August 2019 were studied retrospectively. Materialise Mimics software and the multiplanar reconstruction method were used for evaluation, based on 3D-TEE and CT. The annulus area-derived diameter, the annulus perimeter-derived diameter (Dp), the annulus mean diameter, the left ventricular outflow tract Dp diameter, the sinotubular junction (STJ) diameter-Dp, and the aortic sinus diameter were compared and analyzed. Part II: 31 of 233 patients whose 3D-TEE and CT data were well preserved and in the required format were included. HU450 and HU850 were used as indicators to measure the severity of calcification. The Spearman rank correlation and Linear regression were used to analyze the correlation between aortic root calcification and the accuracy of 3D-TEE in aortic annulus measurement. Results The measurement results based on 3D-TEE were significantly lower than those obtained using CT (P < 0.05), except for the STJ diameter-Dp in diastole (P = 0.11). The correlation coefficient of the two groups was 0.699–0.954 (P < 0.01), which also indicated a significant correlation between the two groups. A Bland–Altman plot showed that the ordinate values were mostly within the 95% consistency limit; the consistency of the two groups was good. By establishing the linear regression equation, the two groups can be inferred from each other. The Spearman rank correlation analysis and the Linear regression analysis showed that the influence of aortic calcification on the accuracy of the 3D-TEE annulus evaluation was limited. Conclusions Although an evaluation based on 3D-TEE underestimated the results, we can deduce CT results from 3D-TEE because the two methods exhibit considerable correlation and consistency. Trial registration Name: Surgery and Transcatheter Intervention for Structural Heart Diseases. Number: NCT02917980. URL: https://clinicaltrials.gov/ct2/results?term=NCT02917980.

scholarly journals Inverse Associations Between Circulating Secreted Frizzled Related Protein 2 (sFRP2) and Cardiometabolic Risk Factors

2021 ◽  
Vol 8 ◽  
Author(s):  
Mengying Cao ◽  
Hao Wang ◽  
Wenshu Li ◽  
Xueli Jiang ◽  
Xiaolin Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Regression Analysis ◽  
Cardiometabolic Risk ◽  
Rank Correlation ◽  
Left Ventricular ◽  
Related Protein ◽  
Spearman Rank Correlation ◽  
Spearman Rank ◽  
Spearman Rank Correlation Analysis ◽  
Hs Crp

Background: Secreted frizzled-related protein 2 (sFRP2) plays an important role in metabolic syndrome and cardiovascular diseases (CVDs); However, its relevance with cardiometabolic diseases remains to be elucidated. We aimed to determine the serum levels of sFRP2 in patients at different stages of heart failure (HF) with or without type 2 diabetes mellitus (T2DM), and assess the correlation between circulating sFRP2 levels and cardiometabolic risk factors.Methods: In this study, serum samples from 277 patients visiting Zhongshan Hospital affiliated to Fudan University were collected. These patients were clinically diagnosed and categorized as five groups, including the control group, pre-clinical HF group, pre-clinical HF+T2DM group, HF group and HF+T2DM group. Serum sFRP2 levels were measured with enzyme-linked immunosorbent assay (ELISA) tests and the clinical characteristics of each patient were recorded. Spearman rank correlation analysis and multiple stepwise linear regression analysis were conducted. Univariate and multivariate logistic regression analysis were performed to screen risk factors for HF in patients with CVDs.Results: Serum sFRP2 levels were significantly lower in the HF+T2DM group compared with the other four groups. Spearman rank correlation analysis showed that sFRP2 was negatively correlated with parameters including patients' age, fasting plasma glucose (FPG), glycated hemoglobin A1c (HbA1c), cardiac troponin T (cTNT), N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity C-reactive protein (hs-CRP), left atrial dimension (LAD) and left ventricular posterior wall (LVPW), and positively correlated with hemoglobin, estimated glomerular filtration rate (eGFR), albumin, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and left ventricular ejection fraction (LVEF). However, in multiple regression analysis, significant associations with ln(sFRP2) were observed only in FPG, hs-CRP and LAD. Higher serum sFRP2 was significantly linked to lower odds of HF in patients with CVDs.Conclusion: sFRP2 progressively decreased when glucose homeostasis and cardiac function deteriorated. sFRP2 acted as a risk factor for HF in patients with CVDs, especially in those with concomitant T2DM.

HUBUNGAN BEBAN KERJA PERAWAT DENGAN KELENGKAPAN PENGISIAN DOKUMENTASI ASUHAN KEPERAWATAN

2020 ◽  
Vol 5 (2) ◽  
pp. 588
Author(s):  
Etlida Wati ◽  
Ulva Arini
Keyword(s):  
Nursing Care ◽  
Rank Correlation ◽  
Bivariate Analysis ◽  
Spearman Rank Correlation ◽  
Cross Sectional ◽  
Weight Category ◽  
Spearman Rank ◽  
Hospital Room ◽  
Analysis Technique ◽  
Nurse Workload

<p>Documentation is an activity of recording, reporting or recording an event and activities carried out in the form of providing services that are considered important and valuable. One factor that can influence documentation is the nurse's workload. The purpose of this study is to identify the relationship between nurses' workload and the application of documentation in the Hj. Anna Lasmanah Banjarnegara. This  research is quantitative with a cross sectional approach descriptive correlation design. Samples were taken with a total sampling of 65 nurses. Instruments to measure documentation using observation sheets. While the nurse workload instrument uses a questionnaire sheet. The analysis technique uses Spearman Rank correlation. Based on the research results of the workload of a nurse in the hospital room , most of them are in the weight category, as many as 46 respondents (70.8%). Application of nursing care documentation in the hospital room Hj. Anna Lasmanah Banjarnegara, most of them are respondents in the incomplete category as many as 63 respondents (96.9%). There is a significant relationship between nurse workload with the application of documentation, this is evidenced by the results of the Spearman Rank correlation bivariate analysis, which is r = 0.688 with p = 0.000 &lt;0.05. It is hoped that management will motivate nurses to complete the documentation of nursing care</p>

scholarly journals Does continuity in nursing staff matter? A pilot study on correlation of central line-associated bloodstream infections and employee turnover

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Thomas Scheier ◽  
Stefan P. Kuster ◽  
Mesida Dunic ◽  
Christian Falk ◽  
Hugo Sax ◽  
...  
Keyword(s):  
Nursing Staff ◽  
Employee Turnover ◽  
Rank Correlation ◽  
Bloodstream Infections ◽  
Central Line ◽  
Incidence Rates ◽  
Nursing Personnel ◽  
Care Hospital ◽  
Spearman Rank Correlation ◽  
Spearman Rank

Abstract Background Understaffing has been previously reported as a risk factor for central line-associated bloodstream infections (CLABSI). No previous study addressed the question whether fluctuations in staffing have an impact on CLABSI incidence. We analyzed prospectively collected CLABSI surveillance data and data on employee turnover of health care workers (HCW) to address this research question. Methods In January 2016, a semiautomatic surveillance system for CLABSI was implemented at the University Hospital Zurich, a 940 bed tertiary care hospital in Switzerland. Monthly incidence rates (CLABSI/1000 catheter days) were calculated and correlations with human resources management-derived data on employee turnover of HCWs (defined as number of leaving HCWs per month divided by the number of employed HCWs) investigated. Results Over a period of 24 months, we detected on the hospital level a positive correlation of CLABSI incidence rates and turnover of nursing personnel (Spearman rank correlation, r = 0.467, P = 0.022). In more detailed analyses on the professional training of nursing personnel, a correlation of CLABSI incidence rates and licensed practical nurses (Spearman rank correlation, r = 0.26, P = 0.038) or registered nurses (r = 0.471, P = 0.021) was found. Physician turnover did not correlate with CLABSI incidence (Spearman rank correlation, r =  −0.058, P = 0.787). Conclusions Prospectively determined CLABSI incidence correlated positively with the degree of turnover of nurses overall and nurses with advanced training, but not with the turnover of physicians. Efforts to maintain continuity in nursing staff might be helpful for sustained reduction in CLABSI rates.

scholarly journals In vivo calibration of the T2* cardiovascular magnetic resonance method at 1.5 T for estimation of cardiac iron in a minipig model of transfusional iron overload

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Peter Diedrich Jensen ◽  
Asbjørn Haaning Nielsen ◽  
Carsten Wiberg Simonsen ◽  
Ulrik Thorngren Baandrup ◽  
Svend Eggert Jensen ◽  
...  
Keyword(s):  
Rank Correlation ◽  
Calibration Data ◽  
Iron Loading ◽  
Spearman Rank Correlation ◽  
Calibration Equation ◽  
Spearman Rank ◽  
Cardiac Iron ◽  
In Vivo Calibration ◽  
Spearman Rank Correlation Coefficient

Abstract Background Non-invasive estimation of the cardiac iron concentration (CIC) by T2* cardiovascular magnetic resonance (CMR) has been validated repeatedly and is in widespread clinical use. However, calibration data are limited, and mostly from post-mortem studies. In the present study, we performed an in vivo calibration in a dextran-iron loaded minipig model. Methods R2* (= 1/T2*) was assessed in vivo by 1.5 T CMR in the cardiac septum. Chemical CIC was assessed by inductively coupled plasma-optical emission spectroscopy in endomyocardial catheter biopsies (EMBs) from cardiac septum taken during follow up of 11 minipigs on dextran-iron loading, and also in full-wall biopsies from cardiac septum, taken post-mortem in another 16  minipigs, after completed iron loading. Results A strong correlation could be demonstrated between chemical CIC in 55 EMBs and parallel cardiac T2* (Spearman rank correlation coefficient 0.72, P < 0.001). Regression analysis led to [CIC] = (R2* − 17.16)/41.12 for the calibration equation with CIC in mg/g dry weight and R2* in Hz. An even stronger correlation was found, when chemical CIC was measured by full-wall biopsies from cardiac septum, taken immediately after euthanasia, in connection with the last CMR session after finished iron loading (Spearman rank correlation coefficient 0.95 (P < 0.001). Regression analysis led to the calibration equation [CIC] = (R2* − 17.2)/31.8. Conclusions Calibration of cardiac T2* by EMBs is possible in the minipig model but is less accurate than by full-wall biopsies. Likely explanations are sampling error, variable content of non-iron containing tissue and smaller biopsies, when using catheter biopsies. The results further validate the CMR T2* technique for estimation of cardiac iron in conditions with iron overload and add to the limited calibration data published earlier.

scholarly journals Interactional Justice and Employees’ Commitment to Supervisor in Nigerian Health Sector

2015 ◽  
Vol 2 (5) ◽  
pp. 7-17 ◽  
Author(s):  
Ajogwu Akoh ◽  
Edwinah Amah
Keyword(s):  
Health Sector ◽  
Rank Correlation ◽  
Interactional Justice ◽  
Survey Questionnaire ◽  
Spearman Rank Correlation ◽  
Interpersonal Justice ◽  
Informational Justice ◽  
Spearman Rank ◽  
The Relationship ◽  
Spearman Rank Correlation Coefficient

This research was designed to study the relationship between interactional justice and employees’ commitment to supervisor in Nigerian health sector. A self-administered survey questionnaire was sent out to a sample size of 103 employees, resulting in 99 responses out of which 13 copies of the questionnaire were not statistically usable. The Spearman rank correlation coefficient was used for data analysis, and our findings reveal that employees who have received fair informational and interpersonal treatments commit themselves to their supervisors. We discovered that the degree of influence exerted by interpersonal justice on employees’ commitment to supervisor was stronger than that of informational justice. We concluded that employees attach themselves to supervisors that are fair in communication and relationship. The fairness of interaction and communication boost employees’ confidence, impacting positively on employees’ commitment to supervisor and making employees see themselves as part owners in the organization. We, therefore, recommended that organizational managers or supervisors should communicate and relate properly with employees, in order to satisfy their customers and other stakeholders.

scholarly journals Analisis Faktor-Faktor Yangberhubungandengan Motivasi Petani Dalam Berusahatani Lada Di Kabupaten Aceh Besar

2016 ◽  
Vol 1 (1) ◽  
pp. 394-409
Author(s):  
Zainuddin Zainuddin ◽  
Safrida Safrida ◽  
Elvira Iskandar
Keyword(s):  
Rank Correlation ◽  
Measurement Scale ◽  
Primary Data ◽  
Spearman Rank Correlation ◽  
West Kalimantan ◽  
Spearman Rank ◽  
Aceh Province ◽  
Level Of Motivation ◽  
Service Agencies ◽  
Pepper Plants

ABSTRACTOne of the commodities that became the mainstay of Indonesia's exports is commodities pepper. In Indonesia, many pepper plants grown in the provinces of Lampung, Bangka, West Kalimantan and Aceh. Pepper plants in several regencies / cities in Aceh province. However, the development of commodity pepper planting area tends to decrease in almost every district. Aceh Besar district as a granary, pepper production in Aceh province also decreased acreage planting area. This condition is very contradictory because demand and prices of pepper are high but has not been used optimally. This is a reflection of the low motivation of farmers in pepper farming. The purpose of this study was to determine the level of motivation pepper farmers and determine the factors related to the motivation of farmers. The data analysis method used is Likert measurement scale systems and Spearman rank correlation. The data used are primary data time series period 2008-2013. Based on test results using a Likert scale of measurement that the level of motivation of farmers in pepper farming in Aceh Besar district in the high category. Based on the factors that have been tested using Spearman rank correlation, it is known that factors related to the level of motivation of farmers in pepper farming is the motivation of farmers with the availability of inputs, farmers motivated by cosmopolitan nature of farmers, and the motivation of farmers by supporting institutions. While revenue and service agencies there are not to relation with the motivation of pepper farmers. Keywords: Pepper Farm, Farmer Motivation Levels, External Factors, Spearman Rank Correlation

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