Evaluating the interchangeability of infrared and digital devices with the traditional mercury thermometer in hospitalized pediatric patients: an observational study.

Abstract A gradual replacement of the mercury thermometers with alternative devices is ongoing around the world as effect of the global strategies to reduce mercury pollution. However, to reduce the risks of misdiagnosis, unnecessary treatments, and omission of care in the pediatric population, more evidence on the reliability and validity of alternative thermometers are needed. The aim of this comparative observational study was to detect any differences in temperature measurements between the gold-standard axillary mercury thermometer (AXLMER) and the alternative devices. Temperature values in Celsius (°C) were simultaneously measured in a group of Albanian children aged up to 14 years using both (AXLMER) and digital axillary thermometers (AXLDGT), as well as forehead and tympanic infra-red thermometers. The AXLDGT device, compared with the AXLMER, showed no clinically significant difference in the mean values (-0.04 ± 0.29 °C) and the narrowest 95% Level of Agreement (+0.53 °C to -0.62 °C) in the paired comparisons. For cut-off points of 37.0 °C and 37.5 °C, the AXLDGT showed the highest levels of sensitivity (67.4% and 72.5%) and specificity (95.3% and 99.1%) in detecting fever. This study indicates that the AXLDGT thermometer may prove the better option since it adequately balances accuracy, safety and children’s comfort.

Download Full-text

Evaluating the interchangeability of infrared and digital devices with the traditional mercury thermometer in hospitalized pediatric patients: an observational study

Scientific Reports ◽

10.1038/s41598-021-96587-y ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Angelo Dante ◽

Elona Gaxhja ◽

Vittorio Masotta ◽

Carmen La Cerra ◽

Valeria Caponnetto ◽

...

Keyword(s):

Observational Study ◽

Mean Values ◽

Digital Devices ◽

Significant Difference ◽

Mercury Thermometer ◽

Pediatric Populations ◽

The Mean ◽

Alternative Techniques ◽

Clinically Significant ◽

Level Of Agreement

AbstractGradual replacement of the mercury thermometers with alternative devices is ongoing around the world in a bid to protect human health and the environment from the adverse effects of mercury. However, to reduce the risks of misdiagnosis, unnecessary treatments, and omission of care in pediatric populations, more evidence on the reliability of alternative thermometers is needed. The aim of this comparative observational study was to detect any differences in temperature measurements between the use of the axillary mercury thermometer and the alternative techniques. Temperature values in degree Celsius (°C) were measured in a group of Albanian children aged up to 14 years using mercury and digital axillary thermometers, as well as forehead and tympanic infrared thermometers. The digital axillary device, compared with the mercury one, showed no clinically significant difference in the mean values (− 0.04 ± 0.29 °C) and the narrowest 95% level of agreement (+ 0.53 °C to − 0.62 °C) in the paired comparisons. For cut-off point of 37.5 °C, the digital axillary thermometer showed the highest levels of sensitivity (72.5%) and specificity (99.1%) in detecting fever. This study indicates that the digital axillary thermometer may be the better option since it adequately balances accuracy, safety, and children’s comfort.

Download Full-text

Perbandingan Proporsi Antibodi Ireguler pada Pasien Multitransfusi dan Pasien Non Multitransfusi di UTD RSUP Dr. Mohammad Hoesin Palembang

Jurnal Surya Medika ◽

10.33084/jsm.v7i1.2630 ◽

2021 ◽

Vol 7 (1) ◽

pp. 9-14

Author(s):

Amalia Amalia ◽

Zen Hafy ◽

Phey Liana

Keyword(s):

Observational Study ◽

P Value ◽

Blood Transfusions ◽

Chi Square ◽

Cross Sectional ◽

Significant Difference ◽

Clinical Diagnoses ◽

Clinically Significant ◽

Cross Sectional Design ◽

Transfusion Reactions

Irregular antibodies or "unexpected antibodies" are antibodies other than antibody A and antibody B that can occur due to pregnancy and blood transfusions. Patients who frequently perform transfusions (multitransfusions) are more at risk of forming irregular antibodies because the frequency of exposure to donor red blood cell antigens is more frequent. Irregular antibodies are clinically significant because they can cause hemolysis (erythrocyte alloantibodies), febrile non-hemolytic transfusion reactions (leukocyte alloantibodies), or refractory platelet transfusions (platelet alloantibodies). This research aims to compare the proportion of irregular antibodies in multitransfusion patients and non-multi transfused patients at UTD Dr. Mohammad Hoesin Palembang. This research is an analytic observational study with a cross-sectional design conducted on 2 groups of subjects, 45 each sample. Antibody identification in each group was carried out. Chi-Square analyzed the proportion of irregular antibodies. An analysis of the types of antibodies found and the accompanying clinical diagnoses were carried out. This study showed a significant difference in the proportion of irregular antibodies between the multitransfusion and non-multitransfusion groups with a p-value of 0.001. The types of irregular antibodies found anti-c, Fya, Lea, M, Kpa, LubkKpb, and the clinical diagnoses that found irregular antibodies were anemia, thalassemia, and AIHA.

Download Full-text

CADAVERIC MEASUREMENT AND ANALYSIS OF INTERSCALENE TRIANGLE AND COSTO-CLAVICULAR SPACES IN RELATION TO THORACIC OUTLET SYNDROME

Revista Argentina de Anatomía Clínica ◽

10.31051/1852.8023.v12.n2.28585 ◽

2020 ◽

Vol 12 (2) ◽

pp. 67-75

Author(s):

Subhramoy Chaudhury ◽

Anasuya Ghosh

Keyword(s):

Thoracic Outlet Syndrome ◽

Male And Female ◽

Mean Values ◽

Significant Difference ◽

Measurement And Analysis ◽

Planning Treatment ◽

The Mean ◽

Clinically Significant ◽

Space Material ◽

Base Width

Objectives: Thoracic outlet syndrome (TOS) is an upper extremity disorder resulting from compression of brachial plexus structures and subclavian vessels within thoracic outlet region at any of the three primary sites- interscalene triangle, costoclavicular space and retro-pectoralis minor space. This study focused on detailed anatomic exploration and measurement of normal anatomic variability within interscalene triangle and costoclavicular space. Material and Method: We examined 49 cadavers (22 male and 27 female) and dissected both sides to explore and examine 98 dissected areas. We measured the base width, height, angle within interscalene triangle and the vertical distance within costoclavicular space. We also calculated the area of interscalene triangle. Results: The mean values of base width, height, interscalene angulation of interscalene triangle and height of costoclavular space was 10.18±4.31 mm, 45.19±0.07mm, 10.85±0.06 degrees and 10.22±0.07 mm respectively. The mean area of interscalene triangle was 214.82±5.22sqmm. Conclusion: We have found clinically significant differences between the interscalene and costiclavicular space vertical heights; the height of costoclavicular space was clinically significantly lower than the interscalene space (p< 0.001). No clinical significant difference was found between male and female measurements. These ranges of dataset could be useful for planning treatment approaches in TOS.

Download Full-text

Comparative Study of Refraction between Wave Front-Based Refraction and Autorefraction without and with Cycloplegia in Children and Adolescents

Children ◽

10.3390/children9010088 ◽

2022 ◽

Vol 9 (1) ◽

pp. 88

Author(s):

Ana M Calvo-Maroto ◽

Sara Llorente-González ◽

Jaione Bezunartea-Bezunartea ◽

Francisco Javier Hurtado-Ceña ◽

Clara Berrozpe-Villabona ◽

...

Keyword(s):

Observational Study ◽

Comparative Study ◽

Children And Adolescents ◽

Wave Front ◽

A Value ◽

Significant Difference ◽

The Mean ◽

Clinically Significant

The main aim of this study was to compare refraction measurements with and without cycloplegia from two refractors devices, (TRK-2P autorefractometer (TRK-2P) and wavefront-based refraction Visionix 130 (VX130)) in children and adolescents. This descriptive observational study included 20 myopic eyes and 40 hyperopic eyes measured in two different Spanish hospitals. Cycloplegia was carried out by three drops of cyclopentolate hydrochloride 1% (Colircusí cycloplegic, Alcon Healthcare S.A., Barcelona). The mean age of the myopia group was 12.40 ± 3.48 years; for the hyperopia group, the mean age was 7.37 ± 2.47 years. In the myopia group, autorefraction and wavefront-based refraction did not show clinically significant differences in any components between with and without cycloplegia. The hyperopia group showed statistical and clinically significant differences in sphere and SE components between relaxed and non-relaxed states of accommodation, although the cylindrical components were not clinically different. In this study, we considered a value of ≥0.50D as a clinically significant difference in refraction. Therefore, both devices were capable of obtaining accurate refractions without cyclopegia in myopia children, although they did not avoid instrument myopia and accommodation involved in hyperopia children. Moreover, both refractometers could be useful for astigmatism monitoring in children without the need for cycloplegic drops.

Download Full-text

A clinical survey on the electrocardiogram after intravenous granisetron hydrochloride administration in clinically normal dogs

Journal of the Hellenic Veterinary Medical Society ◽

10.12681/jhvms.26754 ◽

2021 ◽

Vol 72 (1) ◽

pp. 2695

Author(s):

H GHAEMI ◽

H SALARI SEDIGH ◽

M SELK GHAFFARI

Keyword(s):

Heart Rate ◽

Control Group ◽

Mean Values ◽

Time Points ◽

Antiemetic Agent ◽

Clinically Normal ◽

St Segment ◽

Significant Difference ◽

Baseline Values ◽

Clinically Significant

Cardiac side effect of 5-hydroxytryptamine-3 receptor antagonists has been a concern for clinicians. There is a substantial need for greater clarity about the safety of granisetron hydrochloride, an antiemetic agent of this class used in oncological and parvoviral gastroenteritis with acute vomiting in dogs. This study aimed to assess the electrocardiographic effects of a single dose of intravenous granisetron. We randomly assigned 16 adult crossbreed female healthy dogs into two groups of intervention and control and injected them intravenously with granisetron and normal saline, respectively, at a dose of 0.5 ml/kg over one minute. Standard electrocardiography (ECG) was recorded at the baseline, as well as 5, 15, 30, 60, 120, 360, and 720 minutes after the intervention. Heart rate and ECG parameters (PR intervals, QRS duration, ST-segment, T-wave amplitudes, QT, JT, QTc and JTc intervals) were evaluated in lead II.No significant difference was observed between the intervention and the control groups in any of the measured variables at any of the time-points. Mean values of measured parameters showed no significant difference compared with baseline values in the control group, while the granisetron group saw statistically significant but clinically asymptomatic changes in heart rate, PR, QRS, QT, JT, and QTc at different time-points, compared to the baseline values (P<0.05). In conclusion, Granisetron administration was not associated with clinically significant adverse effects on ECG variables or heart rate. Thus, it can be regarded as a relatively safe drug.

Download Full-text

Impact of music in reducing patient anxiety during pediatric ultrasound

Pediatric Reports ◽

10.4081/pr.2016.6349 ◽

2016 ◽

Vol 8 (1) ◽

Cited By ~ 1

Author(s):

Andrew Kesselman ◽

Michael Bergen ◽

Dimitre Stefanov ◽

Rachelle Goldfisher ◽

John Amodio

Keyword(s):

Heart Rate ◽

Pediatric Population ◽

Effective Means ◽

Patient Anxiety ◽

Initial Image ◽

Mean Values ◽

Scan Time ◽

Subjective Scale ◽

Significant Difference ◽

Procedure Room

The use of noninvasive ultrasound examinations can potentially result in significant anxiety in the pediatric population. The purpose of this study was to assess the influence of music during pediatric ultrasound examinations to reduce anxiety measured by heart rate. A total of 44 patients were recruited; 21 controls and 23 experimental. Each participant was randomized to either music or no music (control) after parental consent was obtained. Pulse oximeters were used to monitor heart rate at 15 second intervals for a total of 1 minute, with mean values calculated prior to entering the procedure room, during the middle of the procedure, and after the procedure was completed. The total scan time was determined from the initial image acquisition until the last image recorded by the ultrasound technologist. At the completion of each procedure, the ultrasound technologist scored the ease of performance for the scan on a subjective scale of 1-10 based on prior experience. When utilizing music during pediatric ultrasounds examinations, our study demonstrated significantly decreased heart rate variability from pre-procedural to post-procedural periods. There was no statistical significant difference in total scan time or ultrasound technologist scoring between the two groups. This study demonstrates that music is an inexpensive and effective means of reducing anxiety during pediatric ultrasound as indicated by heart rate.

Download Full-text

Hearing Aid Gain Usage by Children

Language Speech and Hearing Services in Schools ◽

10.1044/0161-1461.2002.149 ◽

1989 ◽

Vol 20 (2) ◽

pp. 149-152 ◽

Cited By ~ 1

Author(s):

Kenneth W. Berger

Keyword(s):

Hearing Aid ◽

Appreciable Difference ◽

Significant Difference ◽

Clinically Significant

Hearing aid gain usage by two groups of children was examined. No appreciable difference was noted between the groups, nor was there a clinically significant difference between gain usage by these children as compared with a sample of adult hearing aid wearers.

Download Full-text

A COMPARISON OF TWO METHODS FOR MEASUREMENT OF ALDOSTERONE SECRETION RATE IN MAN

Acta Endocrinologica ◽

10.1530/acta.0.0530177 ◽

1966 ◽

Vol 53 (2) ◽

pp. 177-188 ◽

Cited By ~ 4

Author(s):

P. Lund-Johansen ◽

T. Thorsen ◽

K. F. Støa

Keyword(s):

Urinary Excretion ◽

Normal Subjects ◽

Secretion Rate ◽

Aldosterone Secretion ◽

Simple Method ◽

Mean Values ◽

Pathological Conditions ◽

Significant Difference ◽

Derivative Method ◽

The Mean

ABSTRACT A comparison has been made between (A), a relatively simple method for the measurement of aldosterone secretion rate, based on paper chromatography and direct densitometry of the aldosterone spot and (B) a more elaborate isotope derivative method. The mean secretion rate in 9 normal subjects was 112 ± 26 μg per 24 hours (method A) and 135 ± 35 μg per 24 hours (method B). The »secretion rate« in one adrenalectomized subject after the intravenous injection of 250 μg of aldosterone was 230 μg per 24 hours (method A) and 294 μg per 24 hours (method B). There was no significant difference in the mean values, and correlation between the two methods was good (r = 0.80). It is concluded that the densitometric method is suitable for clinical purposes as well as research, being more rapid and less expensive than the isotope derivative method. Method A also measures the urinary excretion of the aldosterone 3-oxo-conjugate, which is of interest in many pathological conditions. The densitometric method is obviously the less sensitive and a prerequisite for its use is an aldosterone secretion of 20—30 μg per 24 hours. Lower values are, however, rare in adults.

Download Full-text

Effectiveness of Brushing Associated with Oral Irrigation in Maintenance of Peri-Implant Tissues and Overdentures: Clinical Parameters and Patient Satisfaction.

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-19-00092 ◽

2020 ◽

Author(s):

Marcela Moreira Salles ◽

Viviane de Cássia Oliveira ◽

Ana Paula Macedo ◽

Claudia Helena Silva-Lovato ◽

Helena de Freitas Oliveira Paranhos

Keyword(s):

Patient Satisfaction ◽

Analogue Scale ◽

Ring System ◽

Complete Dentures ◽

Gingival Index ◽

Prosthetic Rehabilitation ◽

Mean Values ◽

Probing Depth ◽

Significant Difference ◽

High Level

Implant-supported prostheses hygiene and peri-implant tissues health are considered to be predictive factors for successful prosthetic rehabilitation. Therefore, the purpose of this study was to evaluate the effectiveness of brushing associated with oral irrigation measured as biofilm-removing capacity, maintenance of healthy oral tissues, and patient satisfaction. A randomized, crossover clinical trial was conducted with 38 patients who wore conventional maxillary complete dentures and mandibular overdentures retained by the O-ring system. The patients were instructed to use the following hygiene methods for 14 days: mechanical brushing [MB (brush and dentifrice - Control)]; and MB with oral irrigation [WP (Waterpik - Experimental)]. Biofilm-removing capacity and maintenance of healthy oral tissues were evaluated by the Modified Plaque Index (PI), Gingival Index (GI), Probing Depth (PD), and Bleeding on Probing Index (BP) recorded at baseline and after each method. In parallel, patients answered a specific questionnaire using a Visual Analogue Scale after each hygiene method. Data were analyzed by Friedman and Wilcoxon tests (α=0.05). The results showed significantly lower PI, GI, PD, and BP indices after application of the hygiene methods (P<0.001) than those observed at baseline. However, no significant difference was found between MB and WP. The satisfaction questionnaire responses to both methods showed high mean values for all questions, with no statistically significant difference found between the answers given after the use of MB and WP (P>0.05). The findings suggest that WP was effective in reducing PI, GI, PD, and BP indices and provided a high level of patient satisfaction.

Download Full-text