scholarly journals Chronic and cumulative adverse life events in patients of premature ovarian insufficiency with unknown cause: an exploratory qualitative study

Author(s):  
Junyan Sun ◽  
Yihui Fan ◽  
Ying Guo ◽  
Huiying Pan ◽  
Chen Zhang ◽  
...  

Abstract Background Premature ovarian insufficiency (POI) has serious physical and psychological consequences due to estrogen deprivation, leading to increased morbidity and mortality. However, the causes of most POI cases remain unknown (idiopathic POI). Environmental factors play an important role in the occurrence of complex diseases. To explore whether chronic and cumulative adverse life events occur in patients before POI diagnosis. Searching for the potential relative risk factors may find an intervention strategy to prevent POI in young women.Results Forty-three women (mean age=33·8 years) were recruited who were newly- diagnosed with idiopathic POI in a Chinese Ob/Gyn hospital to participate in semi-structured interviews through convenience sampling. The main questions covered by the topic guide were designed to explore adverse life events prior to POI diagnosis. Interviews were audio recorded, transcribed and analyzed thematically. Data were analyzed from June 2019 to August 2020. Among the POI patients, the mean age at diagnosis of POI was 33·8 years (range from 19 to 39 years), and the average time between the onset of irregular menstruation and POI diagnosis was 2.3 years. These patients had a relatively normal menstrual cycle before the diagnosis of POI. A number of stressful life events prior to POI diagnosis were discussed by them as important factors influencing their health and well-being. Four core themes emerged: 1) persistent exposure to workplace stress, 2) persistent exposure to family stress, 3) chronic sleep problem/disturbance existed in patients before POI diagnosis, and 4) participants' general cognition and concerns about POI. Conclusions Persistent exposures to adverse life events related to work stress, family stress and sleep disturbance exist in idiopathic POI patients. In addition, patients and their families generally have incorrect cognition of POI disease and its treatment. Future case-control studies should demonstrate whether chronic and cumulative adverse life events are risk factors of POI disease. Provision of tailored interventions (i.e. preventing or mitigating impact of adverse life events) aimed at high-risk populations is urgently needed to prevent new POI cases and promoting understanding of disease may improve health conditions of POI patients.

Author(s):  
Amalia De Leo ◽  
Eloisa Cianci ◽  
Paolo Mastore ◽  
Caterina Gozzoli

The COVID-19 pandemic put the Italian health system under great stress. The sudden reorganization of work practices and the emotional impact of the large number of the victims had many consequences on the well-being of the healthcare professionals (HCPs) involved in managing the crisis. In the available literature, most studies have focused on the risk aspects while only few studies also take into account protective factors. For this reason, it was decided to conduct, within psycho-sociological perspective, a qualitative study with the aim to explore in depth the protective and risk factors as experienced by HCPs who worked in the Italian healthcare system during the COVID-19 outbreak. A total of 19 semi-structured interviews were conducted with HCPs–9 nurses and 10 physicians (7M and 12F) with an average age of 43 (SD = 13.4)–selected using snowball sampling. Considering three different levels of analysis the results highlight the protective and risk factors: personal history level (intrinsic/ethical motivation and flexible role versus extrinsic motivation and static role), interpersonal level (perception of supportive relationships with colleagues, patients, and family versus bad relationships), and organizational level (good leadership and sustainable work purpose versus absence of support from management and undefined or confused tasks).


Author(s):  
Ellen E. Lee ◽  
Baichun Hou ◽  
Ipsit V. Vahia ◽  
Dilip V. Jeste

Late-onset schizophrenia remains an understudied subtype of schizophrenia, despite growing recognition of its impact and distinction from early-onset schizophrenia. This chapter reviews the existing literature on late-onset schizophrenia including beginning with the nomenclature and epidemiology. Then we provide a review of key risk factors and correlates—including genetic risk, sex differences, comorbid sensory loss and physical illness, cognitive and psychiatric symptoms, sociodemographic factors, adverse life events, neuropathology, and inflammation. The chapter ends with clinical issues, including symptoms, differential diagnosis, treatments, and prognosis. Recent studies have examined the role of oestrogen treatments and a new therapy for tardive dyskinesia therapy as well as inflammatory mechanisms in schizophrenia.


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Deva Rangarajan ◽  
Michael Peasley ◽  
Bert Paesbrugghe ◽  
Rajesh V. Srivastava ◽  
Geoffrey T. Stewart

Purpose This study aims to examine the impact of stress as a result of adverse life events on a salesperson’s ability to effectively manage customer relationships. The framework identifies burnout as a key mediating variable and salesperson grit as a coping mechanism. Design/methodology/approach Survey data is gathered from 364 B2B salespeople and investigated using structural equation modeling in Mplus 8.2. Findings The findings reveal adverse life events and their corresponding stress diminish a salesperson’s ability to manage customer relationships effectively through the mediators of reduced personal accomplishment and depersonalization. Thus, negative events of a personal nature can have a significant impact on salesperson outcomes and should be taken with the same level of seriousness as job-related stress. Furthermore, results show that salesperson grit provides mixed results as a coping mechanism. Practical implications The findings indicate that practitioners should be mindful of the negative impact adverse life events can have on work-related outcomes. Organizations and sales managers must be intentional in managing relationships with their salespeople and strategic in the structure they use to manage customer relationships. Recommendations include the use of regular one-on-one meetings to open up a dialogue about work or personal issues the salesperson is experiencing and assigning multiple resources or staff to service valuable customers, thereby not relying on solitary salespeople. Originality/value Employee well-being contributes to firm value; yet, this is the first study in sales to explore the impact of adverse life events on salesperson outcomes.


2011 ◽  
Vol 20 (6) ◽  
pp. 390-394 ◽  
Author(s):  
Mark D. Seery

When adverse life events occur, people often suffer negative consequences for their mental health and well-being. More adversity has been associated with worse outcomes, implying that the absence of life adversity should be optimal. However, some theory and empirical evidence suggest that the experience of facing difficulties can also promote benefits in the form of greater propensity for resilience when dealing with subsequent stressful situations. I review research that demonstrates U-shaped relationships between lifetime adversity exposure and mental health and well-being, functional impairment and health care utilization in chronic back pain, and responses to experimentally induced pain. Specifically, a history of some lifetime adversity predicts better outcomes than not only a history of high adversity but also a history of no adversity. This has important implications for understanding resilience, suggesting that adversity can have benefits.


2021 ◽  
Vol 10 (6) ◽  
pp. 215
Author(s):  
Keunbok Lee

Although the multidimensionality of core discussion networks has been well established and widely studied, studies of the effects of social support on depression rarely consider the multifaceted aspects of dyadic discussion partner ties. This article proposes defining dyadic social relationships as a construct comprising several tie-level attributes and differentiating multiple forms of support relationships by assessing the configuration pattern of multiple attributes. The current study examines various forms of older adults’ discussion partners and identifies which form of discussion partner relationship is effective at buffering the negative effects of adverse life events on depression symptoms. Results from the University of California Social Network Survey show that older adults’ discussion partners can be classified into five distinct types of dyadic ties: spouse/romantic partners, close neighbors, remote type, social companions, and acquaintances. The discussion network with more close neighbor confidants is more effective at buffering the negative effects of adverse life events. These results offer an alternative way of investigating the differential significance of various social support relationships in mental well-being.


Author(s):  
Caroll Hermann

Background: Bonsai integrates relaxation, leisure and art therapy into one medium that can have personal, emotional and commercial value and have benefits beyond the therapist’s couch. The art of bonsai, when used as a therapy tool may affect the capacity of the bonsai practitioner to adjust to negative and stressful life events. Objective: The study was initiated to evaluate the benefit of bonsai on the wellbeing of practitioners of the art. Method: 255 bonsai artists participated in a study that examined the effect of bonsai on their well-being. Semi-structured interviews were conducted with bonsai artists. Results: The majority of participants agreed that being able to work on their bonsais affected their moods positively. Discussion: Although bonsai artists did not report better mental health, participants reported an improvement in their mood when working on a bonsai tree. These findings are significant in that it can be especially useful in settings such as psychiatric hospitals, old age homes, orphanages, prisons, etc., as a preventative measure as well as restorative measures in the well-being of patients.


Author(s):  
S Nobre ◽  
Florencio Vicente Castro ◽  
Juan José Maldonado Briegas

Introduction: This paper draws a research project that aims to understand the psychophysiological gymnastics necessary to cope with the trauma’s “pathosplastic gymnastic”, elucidating the successful or adaptation magic of resilient individuals. As study justification we point motivation and curiosity to obtain an assertive answer to the question: How and Why individuals exposed to dramatic life events didn’t develop PTSD or any psychopathological symptom but reveal their adaptive magic? This answer could not only enlightening protector, vulnerability and risk factors but also if this extraordinary individuals have a singular biology that enable us to find if resilience has a pattern of biomarkers which could provide the interventional tools to promote resilience and prevent breakdown, monitoring psychophysiology of resilience and consequently promote Health and Well-Being.


Sign in / Sign up

Export Citation Format

Share Document