Risk of Suicide Among Patients with Benign Prostatic Hyperplasia in South Korea: A Nationwide Retrospective Cohort Study

Introduction: Psychological health is important to old patients with benign prostatic hyperplasia (BPH) after prostatic surgery. In this retrospective cohort study, we evaluated the effect of personalized preoperative education in the reduction of perioperative anxiety in old BPH patients after prostatic surgery. Methods: Senior patients (≥65 years) admitted with a diagnosis of BPH and scheduled for initial transurethral resection of the prostate from January 1, 2017 to November 30, 2019 were retrieved. Patients in the preoperatively educated group completed the Chinese version of generalized anxiety disorder 7-item scale (GAD-7) form to evaluate their anxiety level at admission and 14 days clinical visits after individual preoperative education. Patients in the control group completed GAD-7 forms but did not receive personalized preoperative education. Patients in both groups discussed their disease with physicians during clinic visits and after admission, and were given an informed consent about their treatment plans. Results: Seven hundred and twenty-four patients were retrieved, including 312 patients who received preoperative education and 412 patients who did not. There were significantly lower postoperative GAD-7 score and fewer moderate to severe postoperative anxiety patients in the preoperatively educated group (p < 0.01). Patients with education above secondary education level had less perioperative anxiety. Conclusion: Personalized education incorporated with shared valuable physiological and psychological experience and expectations dealing with BPH, in comparison to traditional uniformed patient education and informed consent before surgery, may reduce perioperative anxiety more efficiently in BPH patients. A higher educational level helps patients reduce perioperative anxiety before and after their personalized preoperative education.

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Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study

Clinical Therapeutics ◽

10.1016/s0149-2918(01)80022-9 ◽

2001 ◽

Vol 23 (5) ◽

pp. 727-743 ◽

Cited By ~ 25

Author(s):

E Chrischilles

Keyword(s):

Cohort Study ◽

Benign Prostatic Hyperplasia ◽

Adverse Events ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Prostatic Hyperplasia ◽

Antagonist Therapy

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Risk of incident benign prostatic hyperplasia in patients with gout: a retrospective cohort study

Prostate Cancer and Prostatic Diseases ◽

10.1038/s41391-018-0047-8 ◽

2018 ◽

Vol 21 (2) ◽

pp. 277-286 ◽

Cited By ~ 2

Author(s):

Wei-Ming Li ◽

Nelly Pasaribu ◽

Su-Shin Lee ◽

Wen-Chan Tsai ◽

Chia-Yang Li ◽

...

Keyword(s):

Cohort Study ◽

Benign Prostatic Hyperplasia ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Prostatic Hyperplasia

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Status and Determinants of Treatment Outcomes Among New Tuberculosis Patients in South Korea: A Retrospective Cohort Study

Asia Pacific Journal of Public Health ◽

10.1177/10105395211000529 ◽

2021 ◽

pp. 101053952110005

Author(s):

Hyunjin Son ◽

Jeongha Mok ◽

Miyoung Lee ◽

Wonseo Park ◽

Seungjin Kim ◽

...

Keyword(s):

Cohort Study ◽

South Korea ◽

Success Rate ◽

Treatment Outcomes ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Health Care Facilities ◽

Tuberculosis Patients ◽

Lost To Follow Up

This is a retrospective cohort study using notification data in South Korea. We evaluated the nationwide status, regional differences, and the determinants of treatment outcomes among tuberculosis patients. Treatment success rate improved from 77.0% in 2012 to 86.0% in 2015. The lost to follow-up rate was higher among older people, males, and foreign nationals. Health care facilities designated for the Public-Private Mix (PPM) project showed higher success rate and lower rate of lost to follow-up. Moreover, municipalities with low regional deprivation index had higher PPM project coverage. Since there is a large regional difference in the coverage of the PPM project, an additional community-based support program should be implemented, especially for tuberculosis patients residing in region with low PPM project coverage.

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The Prediction and Prognosis of Fungal Infection in Lung Transplant Recipients—A Retrospective Cohort Study in South Korea

Journal of Fungi ◽

10.3390/jof7080639 ◽

2021 ◽

Vol 7 (8) ◽

pp. 639

Author(s):

Yae-Jee Baek ◽

Yun-Suk Cho ◽

Moo-Hyun Kim ◽

Jong-Hoon Hyun ◽

Yu-Jin Sohn ◽

...

Keyword(s):

Cohort Study ◽

South Korea ◽

Fungal Infection ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Lung Transplant ◽

Fungal Infections ◽

Transplant Recipients ◽

Tertiary Center ◽

Lung Transplant Recipients

(1) Background: Lung transplant recipients (LTRs) are at substantial risk of invasive fungal disease (IFD), although no consensus has been reached on the use of antifungal agents (AFAs) after lung transplantation (LTx). This study aimed to assess the risk factors and prognosis of fungal infection after LTx in a single tertiary center in South Korea. (2) Methods: The study population included all patients who underwent LTx between January 2012 and July 2019 at a tertiary hospital. It was a retrospective cohort study. Culture, bronchoscopy, and laboratory findings were reviewed during episodes of infection. (3) Results: Fungus-positive respiratory samples were predominant in the first 90 days and the overall cumulative incidence of Candida spp. was approximately three times higher than that of Aspergillus spp. In the setting of itraconazole administration for 6 months post-LTx, C. glabrata accounted for 36.5% of all Candida-positive respiratory samples. Underlying connective tissue disease-associated interstitial lung disease, use of AFAs before LTx, a longer length of hospital stay after LTx, and old age were associated with developing a fungal infection after LTx. IFD and fungal infection treatment failure significantly increased overall mortality. Host factors, antifungal drug resistance, and misdiagnosis of non-Aspergillus molds could attribute to the breakthrough fungal infections. (4) Conclusions: Careful bronchoscopy, prompt fungus culture, and appropriate use of antifungal therapies are recommended during the first year after LTx.

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PCN96 Economic Burden of BRAIN Metastasis in NON SMALL CELL LUNG Cancer in South Korea: Nationwide Retrospective Cohort Study

Value in Health ◽

10.1016/j.jval.2020.08.233 ◽

2020 ◽

Vol 23 ◽

pp. S439

Author(s):

Y.B. Shim ◽

J.Y. Byun ◽

P. Mi-Hai

Keyword(s):

Lung Cancer ◽

Cohort Study ◽

Brain Metastasis ◽

South Korea ◽

Small Cell Lung Cancer ◽

Economic Burden ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Small Cell ◽

Small Cell Lung

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Comparative Risk of Incidence and Clinical Outcomes of COVID-19 among Proton Pump Inhibitor and Histamine-2 Receptor Antagonist Users: A Nationwide Retrospective Cohort Study

10.21203/rs.3.rs-882550/v1 ◽

2021 ◽

Author(s):

Jimyung Park ◽

Seng Chan You ◽

Jaehyeong Cho ◽

Chan Hyuk Park ◽

Woon Shin ◽

...

Keyword(s):

Cohort Study ◽

South Korea ◽

Receptor Antagonist ◽

Clinical Outcomes ◽

Respiratory Disease ◽

Proton Pump ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Large Scale ◽

All Cause Mortality

Abstract Background: This study aimed to evaluate incidence risk and severe clinical outcomes in COVID-19 disease among short-term users of acid-suppressants in South Korea.Methods: This retrospective cohort study, conducted using a nationwide claims database for South Korea, used data from patients with COVID-19 tested between January 1 and May 15, 2020. Patients aged over 18 years and prescribed proton pump inhibitors (PPI) or histamine-2 receptor antagonist (H2RA) for more than 7 days were identified. Primary outcome was COVID-19 while secondary outcomes were all-cause mortality, hospitalization with respiratory disease, or intensive respiratory intervention. Large-scale propensity scores were used to match patients, while the Cox proportional hazard model was utilized to evaluate any association between exposure and outcome(s). The risk estimates were calibrated by using 123 falsification endpoints.Results: We identified 26,166 PPI users and 62,117 H2RA users. After propensity score matching, compared to H2RA use, PPI use was not significantly associated with lower risk of COVID-19 (calibrated hazard ratio [HR], 0.81 [95% confidence interval (CI), 0.30–2.19]); moreover, PPI use was not associated with adverse clinical outcomes in COVID-19, namely, hospitalization with respiratory disease (calibrated HR, 0.88 [95% CI, 0.72–1.08]), intensive respiratory interventions (calibrated HR, 0.92 [95% CI, 0.46–1.82]), except for all-cause mortality (calibrated HR, 0.54 [95% CI, 0.31–0.95]).Conclusions: In this study, we found that the PPI user was not associated with risk of COVID-19 compared to H2RA users. There was no significant relationship between severe clinical outcomes of COVID-19 and exposure to PPI compared with H2RA, except for all-cause mortality.

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