A Study on Detection of COVID-19 in Lung CT Images Using Transfer Learning with Resnet Pre-Trained Model

2021 ◽  
Author(s):  
Rajeswari R .
Keyword(s):  
Author(s):  
SHIWEI LI ◽  
DANDAN LIU

This study aimed to propose an effective malignant solitary pulmonary nodule classification method based on improved Faster R-CNN and transfer learning strategy. In practice, the existing solitary pulmonary nodule classification methods divide the lung cancer images into two categories only: normal and cancerous. This study proposed the deep convolution neural network to classify the computed tomography (CT) images of lung cancer into four categories: lung adenocarcinoma, lung squamous cell carcinoma, metastatic lung cancer, and normal types of lung cancer. Some high-resolution lung CT images have unnecessary characters such as a large number of high-density continuity features, small-size lung nodule targets, CT image background complexity, and so forth. In this study, the CT image sub-block preprocessing strategy was used to extract nodule features for enhancement and alleviate the aforementioned problems. The experimental results showed that the proposed system was effective in resolving issues such as high false-positive rate and long classification time cost based on the original Faster R-CNN detection method. Meanwhile, the transfer learning strategy was used to improve the classification efficiency so as to avoid the overfitting problem caused by a few labeled samples of lung cancer datasets. The classification results were integrated using the majority vote algorithm. The classification results of the lung CT imaging showed that the proposed method had an average detection accuracy of 89.7% and reduced the rate of misdiagnosis to meet the clinical needs.


2021 ◽  
Vol 11 (9) ◽  
pp. 4233
Author(s):  
Biprodip Pal ◽  
Debashis Gupta ◽  
Md. Rashed-Al-Mahfuz ◽  
Salem A. Alyami ◽  
Mohammad Ali Moni

The COVID-19 pandemic requires the rapid isolation of infected patients. Thus, high-sensitivity radiology images could be a key technique to diagnose patients besides the polymerase chain reaction approach. Deep learning algorithms are proposed in several studies to detect COVID-19 symptoms due to the success in chest radiography image classification, cost efficiency, lack of expert radiologists, and the need for faster processing in the pandemic area. Most of the promising algorithms proposed in different studies are based on pre-trained deep learning models. Such open-source models and lack of variation in the radiology image-capturing environment make the diagnosis system vulnerable to adversarial attacks such as fast gradient sign method (FGSM) attack. This study therefore explored the potential vulnerability of pre-trained convolutional neural network algorithms to the FGSM attack in terms of two frequently used models, VGG16 and Inception-v3. Firstly, we developed two transfer learning models for X-ray and CT image-based COVID-19 classification and analyzed the performance extensively in terms of accuracy, precision, recall, and AUC. Secondly, our study illustrates that misclassification can occur with a very minor perturbation magnitude, such as 0.009 and 0.003 for the FGSM attack in these models for X-ray and CT images, respectively, without any effect on the visual perceptibility of the perturbation. In addition, we demonstrated that successful FGSM attack can decrease the classification performance to 16.67% and 55.56% for X-ray images, as well as 36% and 40% in the case of CT images for VGG16 and Inception-v3, respectively, without any human-recognizable perturbation effects in the adversarial images. Finally, we analyzed that correct class probability of any test image which is supposed to be 1, can drop for both considered models and with increased perturbation; it can drop to 0.24 and 0.17 for the VGG16 model in cases of X-ray and CT images, respectively. Thus, despite the need for data sharing and automated diagnosis, practical deployment of such program requires more robustness.


Sensors ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 268
Author(s):  
Yeganeh Jalali ◽  
Mansoor Fateh ◽  
Mohsen Rezvani ◽  
Vahid Abolghasemi ◽  
Mohammad Hossein Anisi

Lung CT image segmentation is a key process in many applications such as lung cancer detection. It is considered a challenging problem due to existing similar image densities in the pulmonary structures, different types of scanners, and scanning protocols. Most of the current semi-automatic segmentation methods rely on human factors therefore it might suffer from lack of accuracy. Another shortcoming of these methods is their high false-positive rate. In recent years, several approaches, based on a deep learning framework, have been effectively applied in medical image segmentation. Among existing deep neural networks, the U-Net has provided great success in this field. In this paper, we propose a deep neural network architecture to perform an automatic lung CT image segmentation process. In the proposed method, several extensive preprocessing techniques are applied to raw CT images. Then, ground truths corresponding to these images are extracted via some morphological operations and manual reforms. Finally, all the prepared images with the corresponding ground truth are fed into a modified U-Net in which the encoder is replaced with a pre-trained ResNet-34 network (referred to as Res BCDU-Net). In the architecture, we employ BConvLSTM (Bidirectional Convolutional Long Short-term Memory)as an advanced integrator module instead of simple traditional concatenators. This is to merge the extracted feature maps of the corresponding contracting path into the previous expansion of the up-convolutional layer. Finally, a densely connected convolutional layer is utilized for the contracting path. The results of our extensive experiments on lung CT images (LIDC-IDRI database) confirm the effectiveness of the proposed method where a dice coefficient index of 97.31% is achieved.


2021 ◽  
Author(s):  
Khalid Labib Alsamadony ◽  
Ertugrul Umut Yildirim ◽  
Guenther Glatz ◽  
Umair bin Waheed ◽  
Sherif M. Hanafy

Abstract Computed tomography (CT) is an important tool to characterize rock samples allowing quantification of physical properties in 3D and 4D. The accuracy of a property delineated from CT data is strongly correlated with the CT image quality. In general, high-quality, lower noise CT Images mandate greater exposure times. With increasing exposure time, however, more wear is put on the X-Ray tube and longer cooldown periods are required, inevitably limiting the temporal resolution of the particular phenomena under investigation. In this work, we propose a deep convolutional neural network (DCNN) based approach to improve the quality of images collected during reduced exposure time scans. First, we convolve long exposure time images from medical CT scanner with a blur kernel to mimic the degradation caused because of reduced exposure time scanning. Subsequently, utilizing the high- and low-quality scan stacks, we train a DCNN. The trained network enables us to restore any low-quality scan for which high-quality reference is not available. Furthermore, we investigate several factors affecting the DCNN performance such as the number of training images, transfer learning strategies, and loss functions. The results indicate that the number of training images is an important factor since the predictive capability of the DCNN improves as the number of training images increases. We illustrate, however, that the requirement for a large training dataset can be reduced by exploiting transfer learning. In addition, training the DCNN on mean squared error (MSE) as a loss function outperforms both mean absolute error (MAE) and Peak signal-to-noise ratio (PSNR) loss functions with respect to image quality metrics. The presented approach enables the prediction of high-quality images from low exposure CT images. Consequently, this allows for continued scanning without the need for X-Ray tube to cool down, thereby maximizing the temporal resolution. This is of particular value for any core flood experiment seeking to capture the underlying dynamics.


Lung cancer is a serious illness which leads to increased mortality rate globally. The identification of lung cancer at the beginning stage is the probable method of improving the survival rate of the patients. Generally, Computed Tomography (CT) scan is applied for finding the location of the tumor and determines the stage of cancer. Existing works has presented an effective diagnosis classification model for CT lung images. This paper designs an effective diagnosis and classification model for CT lung images. The presented model involves different stages namely pre-processing, segmentation, feature extraction and classification. The initial stage includes an adaptive histogram based equalization (AHE) model for image enhancement and bilateral filtering (BF) model for noise removal. The pre-processed images are fed into the second stage of watershed segmentation model for effectively segment the images. Then, a deep learning based Xception model is applied for prominent feature extraction and the classification takes place by the use of logistic regression (LR) classifier. A comprehensive simulation is carried out to ensure the effective classification of the lung CT images using a benchmark dataset. The outcome implied the outstanding performance of the presented model on the applied test images.


2021 ◽  
Vol 9 ◽  
Author(s):  
Jinglun Liang ◽  
Guoliang Ye ◽  
Jianwen Guo ◽  
Qifan Huang ◽  
Shaohui Zhang

Malignant pulmonary nodules are one of the main manifestations of lung cancer in early CT image screening. Since lung cancer may have no early obvious symptoms, it is important to develop a computer-aided detection (CAD) system to assist doctors to detect the malignant pulmonary nodules in the early stage of lung cancer CT diagnosis. Due to the recent successful applications of deep learning in image processing, more and more researchers have been trying to apply it to the diagnosis of pulmonary nodules. However, due to the ratio of nodules and non-nodules samples used in the training and testing datasets usually being different from the practical ratio of lung cancer, the CAD classification systems may easily produce higher false-positives while using this imbalanced dataset. This work introduces a filtering step to remove the irrelevant images from the dataset, and the results show that the false-positives can be reduced and the accuracy can be above 98%. There are two steps in nodule detection. Firstly, the images with pulmonary nodules are screened from the whole lung CT images of the patients. Secondly, the exact locations of pulmonary nodules will be detected using Faster R-CNN. Final results show that this method can effectively detect the pulmonary nodules in the CT images and hence potentially assist doctors in the early diagnosis of lung cancer.


Author(s):  
Houssam BENBRAHIM ◽  
Hanaa HACHIMI ◽  
Aouatif AMINE

The SARS-CoV-2 (COVID-19) has propagated rapidly around the world, and it became a global pandemic. It has generated a catastrophic effect on public health. Thus, it is crucial to discover positive cases as early as possible to treat touched patients fastly. Chest CT is one of the methods that play a significant role in diagnosing 2019-nCoV acute respiratory disease. The implementation of advanced deep learning techniques combined with radiological imaging can be helpful for the precise detection of the novel coronavirus. It can also be assistive to surmount the difficult situation of the lack of medical skills and specialized doctors in remote regions. This paper presented Deep Transfer Learning Pipelines with Apache Spark and KerasTensorFlow combined with the Logistic Regression algorithm for automatic COVID-19 detection in chest CT images, using Convolutional Neural Network (CNN) based models VGG16, VGG19, and Xception. Our model produced a classification accuracy of 85.64, 84.25, and 82.87 %, respectively, for VGG16, VGG19, and Xception. HIGHLIGHTS Deep Transfer Learning Pipelines with Apache Spark and Keras TensorFlow combined with Logistic Regression using CT images to screen for Corona Virus Disease (COVID-19)       Automatic detection of  COVID-19 in chest CT images Convolutional Neural Network (CNN) based models VGG16, VGG19, and Xception to predict COVID-19 in Computed Tomography image GRAPHICAL ABSTRACT


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