Influence of soil main treatment on the agrobiological indicators of the the Vulcan hybrid sunflower under the conditions of the Central zone of the Krasnodar Territory

2019 ◽  
Vol 1 (78) ◽  
pp. 86-90
Author(s):  
Roman Kravchenko ◽  
◽  
Anzhelika Tolstykh ◽  
Keyword(s):  
Central Zone ◽  
Hybrid Sunflower

Influence of corneal biomechanical properties on IOP indices in patients with keratoconus

The Eye ◽  
2019 ◽  
Vol 21 (128) ◽  
pp. 15-19
Author(s):  
Irina Bubnova ◽  
Veronica Averich ◽  
Elena Belousova
Keyword(s):  
Disease Progression ◽  
Corneal Thickness ◽  
Central Zone ◽  
Biomechanical Properties ◽  
Resistance Factor ◽  
Corneal Resistance Factor ◽  
Mean Values ◽  
Coefficient Of Elasticity ◽  
D Values ◽  
Corneal Biomechanical Properties

Purpose: Evaluation of corneal biomechanical prop¬erties and their influence on IOP indices in patients with keratoconus. Material and methods. The study included 194 eyes with keratoconus (113 patients aged from 23 to 36 years old). Corneal refraction in central zone varied from 48.25 to 56.75 D, values of corneal thickness ranged from 279 to 558 μm. Patients were divided into 4 groups according to Amsler classification: I stage – 40 eyes; II stage – 78 eyes; III stage – 54 eyes and IV stage – 22 eyes. Standard ophthal¬mological examination was carried out including pneumo¬tonometry. IOP indices and values of biomechanical prop¬erties were evaluated by dynamic bidirectional pneumatic applanation and pneumatic impression. Results. Study of corneal biomechanical properties in patients with keratoconus showed a decrease of such biomechanical indices as corneal hysteresis (CH) on aver¬age to 8.42±1.12 mm Hg, corneal resistance factor (CRF) – to 7.45±0.96 mm Hg, coefficient of elasticity (CE) – 5.35± 0.87 mm Hg. Values of these indices strongly depended on the stage of keratoconus. In the whole sample, the aver¬age corneal compensated IOP (IOPcc) amounted to 15.08± 2.43 mm Hg, Goldman IOP (IOPg) was 11.61±2.37 mm Hg and pneumatic tonometry IOP (IOPp) was 10.13±2.94 mm Hg. IOPcc indices didn’t have any statistically significant differ¬ence in dependence on the stage of keratoconus (р>0.473), while in process of disease progression IOPg and IOPp indi¬ces showed statistically significant decrease of mean values. Conclusion. Progression of keratoconus led to a de¬crease in corneal biomechanical properties which deter¬mine reduction of such indices as IOPg and IOPp in contrast to IOPcc.

INCREASING THE PRODUCTIVITY OF YUBILEINY NOVY 142 TOBACCO BY USING THE RAIKAT START GROWTH REGULATOR IN THE CENTRAL ZONE OF KRASNODAR REGION

2020 ◽  
Keyword(s):  
Field Experiments ◽  
Central Zone ◽  
Black Soil ◽  
Plant Parts ◽  
Growth Stimulator ◽  
Russian Research Institute ◽  
Stalk Diameter ◽  
Seedling Plant ◽  
In The Beginning ◽  
Plant Length

Efficiency of new natural growth stimulator Raykat Start for seedling plant growing (tobacco) has been studied on the base of All-Russian research institute of tobacco makhorka and tobacco products. We used west-subcaucasian leached black soil on the experimental field. Laboratorial, greenhouse and field experiments have discovered that soaking seeds in solution with concentration of growth stimulator 0.0001 % during 6 hours leads to germs mass increasing by 70 %. Seeds treatment before sowing with efficient concentration of stimulator (0.0001 %) in combination with further double spraying (in basic stages ofplant development: “cotyledon” and “ready for transplanting” before pulling plants from seedbed) on plants until their total moistening of above earth plant parts leads to increasing plant length from collar to growing point by 32 %, to leaf tips - by 23 %, above earth plant mass - by 78 %, root mass - by 60 %, stalk diameter in collar part - by 25 %. It was also noticed significant decreasing of stalk and root decays (up to 52 %) in areas with plants treated by stimulator. Surviving of transplanted plants treated with Raykat Start was 95 %, they had increased growing and developing rates both in the beginning of field stage and in the end of vegetation. These led to increasing plant length, leaf area, which increased by 31 % and plant productivity which increased by 17.6 %.

Ferulic acid through mitigation of NMDA receptor pathway exerts anxiolytic-like effect in mouse model of maternal separation stress

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Zahra Lorigooini ◽  
Ali Nouri ◽  
Faezeh mottaghinia ◽  
Shima Balali-Dehkordi ◽  
Elham Bijad ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Mouse Model ◽  
Ferulic Acid ◽  
Nmda Receptors ◽  
Effective Dose ◽  
Life Stress ◽  
Receptor Agonist ◽  
Maternal Separation ◽  
Early Life Stress ◽  
Central Zone

AbstractBackgroundExperiencing early-life stress plays an important role in the pathophysiology of anxiety disorders. Ferulic acid is a phenolic compound found in some plants which has several pharmacological properties. N-methyl-D-aspartate (NMDA) receptors are involved in the pathophysiology of mood disorders. In this study we aimed to assess the anxiolytic-like effect of ferulic acid in a mouse model of maternal separation (MS) stress by focusing on the possible involvement of NMDA receptors.MethodsMice were treated with ferulic acid (5 and 40 mg/kg) alone and in combination with NMDA receptor agonist/antagonist. Valid behavioral tests were performed, including open field test (OFT) and elevated plus maze test (EPM), while quantitative real time polymerase chain reaction (qRT-PCR) was used to evaluate gene expression of NMDA subunits (GluN2A and GluN2B) in the hippocampus.ResultsFindings showed that treatment of MS mice with ferulic acid increased the time spent in the central zone of the OFT and increased both open arm time and the percent of open arm entries in the EPM. Ferulic acid reduced the expression of NMDA receptor subunit genes. We showed that administration of NMDA receptor agonist (NMDA) and antagonist (ketamine) exerted anxiogenic and anxiolytic-like effects, correspondingly. Results showed that co-administration of a sub-effective dose of ferulic acid plus ketamine potentiated the anxiolytic-like effect of ferulic acid. Furthermore, co-administration of an effective dose of ferulic acid plus NMDA receptor agonist (NMDA) attenuated the anxiolytic-like effect of ferulic acid.ConclusionsIn deduction, our findings showed that NMDA, partially at least, is involved in the anxiolytic-like effect of ferulic acid in the OFT and EPM tests.

scholarly journals Are we observing an NSC in course of formation in the NGC 4654 galaxy?

2021 ◽  
Vol 503 (1) ◽  
pp. 594-602
Author(s):  
R Schiavi ◽  
R Capuzzo-Dolcetta ◽  
I Y Georgiev ◽  
M Arca-Sedda ◽  
A Mastrobuono-Battisti
Keyword(s):  
Central Zone ◽  
Effective Radius ◽  
Host Galaxy ◽  
Galactic Centre ◽  
Future Evolution ◽  
Orbital Parameters ◽  
Relative Orbit ◽  
The Future ◽  
The Galaxy ◽  
Massive Clusters

ABSTRACT We use direct N-body simulations to explore some possible scenarios for the future evolution of two massive clusters observed towards the centre of NGC 4654, a spiral galaxy with mass similar to that of the Milky Way. Using archival HST data, we obtain the photometric masses of the two clusters, M = 3 × 105 M⊙ and M = 1.7 × 106 M⊙, their half-light radii, Reff ∼ 4 pc and Reff ∼ 6 pc, and their projected distances from the photometric centre of the galaxy (both <22 pc). The knowledge of the structure and separation of these two clusters (∼24 pc) provides a unique view for studying the dynamics of a galactic central zone hosting massive clusters. Varying some of the unknown cluster orbital parameters, we carry out several N-body simulations showing that the future evolution of these clusters will inevitably result in their merger. We find that, mainly depending on the shape of their relative orbit, they will merge into the galactic centre in less than 82 Myr. In addition to the tidal interaction, a proper consideration of the dynamical friction braking would shorten the merging times up to few Myr. We also investigate the possibility to form a massive nuclear star cluster (NSC) in the centre of the galaxy by this process. Our analysis suggests that for low-eccentricity orbits, and relatively long merger times, the final merged cluster is spherical in shape, with an effective radius of few parsecs and a mass within the effective radius of the order of $10^5\, \mathrm{M_{\odot }}$. Because the central density of such a cluster is higher than that of the host galaxy, it is likely that this merger remnant could be the likely embryo of a future NSC.

scholarly journals Petrogenesis of a late-stage calc-alkaline granite in a giant S-type batholith: geochronology and Sr–Nd–Pb isotopes from the Nomatsaus granite (Donkerhoek batholith), Namibia

2021 ◽  
Author(s):  
S. Aspiotis ◽  
S. Jung ◽  
F. Hauff ◽  
R. L. Romer
Keyword(s):  
Partial Melting ◽  
Mineral Assemblage ◽  
Central Zone ◽  
Calc Alkaline ◽  
Pb Isotope ◽  
Alkaline Granite ◽  
Ti Oxides ◽  
Eu Anomaly ◽  
Environment Characteristic ◽  
Southern Central

AbstractThe late-tectonic 511.4 ± 0.6 Ma-old Nomatsaus intrusion (Donkerhoek batholith, Damara orogen, Namibia) consists of moderately peraluminous, magnesian, calc-alkalic to calcic granites similar to I-type granites worldwide. Major and trace-element variations and LREE and HREE concentrations in evolved rocks imply that the fractionated mineral assemblage includes biotite, Fe–Ti oxides, zircon, plagioclase and monazite. Increasing K2O abundance with increasing SiO2 suggests accumulation of K-feldspar; compatible with a small positive Eu anomaly in the most evolved rocks. In comparison with experimental data, the Nomatsaus granite was likely generated from meta-igneous sources of possibly dacitic composition that melted under water-undersaturated conditions (X H2O: 0.25–0.50) and at temperatures between 800 and 850 °C, compatible with the zircon and monazite saturation temperatures of 812 and 852 °C, respectively. The Nomatsaus granite has moderately radiogenic initial 87Sr/86Sr ratios (0.7067–0.7082), relatively radiogenic initial εNd values (− 2.9 to − 4.8) and moderately evolved Pb isotope ratios. Although initial Sr and Nd isotopic compositions of the granite do not vary with SiO2 or MgO contents, fSm/Nd and initial εNd values are negatively correlated indicating limited assimilation of crustal components during monazite-dominated fractional crystallization. The preferred petrogenetic model for the generation of the Nomatsaus granite involves a continent–continent collisional setting with stacking of crustal slices that in combination with high radioactive heat production rates heated the thickened crust, leading to the medium-P/high-T environment characteristic of the southern Central Zone of the Damara orogen. Such a setting promoted partial melting of metasedimentary sources during the initial stages of crustal heating, followed by the partial melting of meta-igneous rocks at mid-crustal levels at higher P–T conditions and relatively late in the orogenic evolution.

scholarly journals Honeybee Pollen Extracts Reduce Oxidative Stress and Steatosis in Hepatic Cells

Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 6
Author(s):  
Juan Esteban Oyarzún ◽  
Marcelo E. Andia ◽  
Sergio Uribe ◽  
Paula Núñez Pizarro ◽  
Gabriel Núñez ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Cell Model ◽  
Radical Scavenging ◽  
Central Zone ◽  
Total Phenolic ◽  
Nonalcoholic Fatty Liver ◽  
Bee Pollen ◽  
Quercetin Concentration

Nonalcoholic fatty liver disease (NAFLD) is a major cause of morbidity and mortality worldwide. Additional therapies using functional foods and dietary supplements have been investigated and used in clinical practice, showing them to be beneficial. Honeybee pollen from Chile has shown a large concentration of phenolic compounds and high antioxidant activity. In this work, we characterized twenty-eight bee pollen extracts from the central zone of Chile according to botanical origin, phenolic profile, quercetin concentration, and antioxidant activity (FRAP and ORAC-FL). Our results show a statistically significant positive correlation between total phenolic content and antioxidant capacity. Selected samples were evaluated on the ability to reverse the steatosis in an in vitro cell model using Hepa1-6 cells. The pollen extracts protected Hepa1-6 cells against oxidative damage triggered by 2,2′-azo-bis(2-amidinopropane) dihydrochloride (AAPH)derived free radicals. This effect can be credited to the ability of the phenolic compounds present in the extract to protect the liver cells from chemical-induced injury, which might be correlated to their free radical scavenging potential. Additionally, bee pollen extracts reduce lipid accumulation in a cellular model of steatosis. In summary, our results support the antioxidant, hepatoprotective, and anti-steatosis effect of bee pollen in an in vitro model.

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