scholarly journals Topical issues in the treatment of chronic tonsillitis

2021 ◽  
pp. 67-73
Author(s):  
A. V. Gurov ◽  
A. V. Muzhichkova ◽  
A. A. Kelemetov
Keyword(s):  
Connective Tissue ◽  
Inflammatory Process ◽  
Subsequent Development ◽  
Chronic Tonsillitis ◽  
Immunological Parameters ◽  
Small Vessels ◽  
Principles Of Treatment ◽  
Walnut Leaves ◽  
Degrees Of Severity

The article is devoted to the problem of chronic tonsillitis. The widespread prevalence of the disease, as well as the high risk of complications from vital organs, make this problem especially urgent. The article describes in detail the factors contributing to the formation of a focus of chronic inflammation in the amygdala. Special attention is paid to the microbiological aspects of the inflammatory process, anatomical, topographic and physiological features of the tonsils, as well as their immune function. The histological changes that form against the background of a long-term chronic inflammatory process in the tonsils are described. Changes in the parenchyma of the amygdala during inflammation can be expressed both by hyperplasia and by involution of follicles with the formation of infiltrates and the subsequent development of abscesses. In the final stages of an active inflammatory process, connective tissue grows, replacing lymphoid tissue. In the paratonsillar tissue and the capsule of the amygdala, an overgrowth of connective tissue is also observed, which is accompanied by the formation of nested infiltrates around small vessels, most pronounced at the upper pole of the amygdala. According to this classification, two clinical forms of chemotherapy are distinguished: simple and toxic-allergic of two degrees of severity. Further, in accordance with this classification, the basic principles of treatment are presented. Then the features of conservative therapy and the benefits of the herbal preparation are described. The composition of this drug includes marshmallow root, chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark and dandelion herb. The results of several clinical trials of the drug indicate its positive effect on the dynamics of both clinical and microbiological, immunological parameters in patients with chronic tonsillitis. All this allows us to recommend wider inclusion of this combined herbal medicinal product in the complex of treatment of chronic tonsillitis.

scholarly journals The role of herbal medicine in the treatment of chronic tonsillitis

2020 ◽  
pp. 36-43 ◽  
Author(s):  
G. S. Maltseva ◽  
S. A. Karpishchenko
Keyword(s):  
Herbal Product ◽  
Chronic Tonsillitis ◽  
Phagocytic Index ◽  
Comprehensive Treatment ◽  
Immunological Parameters ◽  
New Methods ◽  
Walnut Leaves ◽  
Multiresistant Strains

The article presents our own research data on systemic immunity status in patients with chronic tonsillitis (CT) and microbiological profile of the flora isolated from the tonsils in CT. The study showed that phagocytic index in neutrophils decreased by 81.9% and the phagocytosis in neutrophils reduced by 67.2% in patients with CT. We studied microbial flora of the tonsils and its persistent properties in CT. The steps for that were as follows: we evaluated the antilysocyme (ALA), anti-interferon (AIA), anticomplementary (ACA) activities of the isolated microorganisms as possible ways to stand against the oxygen-independent mechanism of phagocytosis. Most strains of Staphylococcus aureus had ALA, AIA and AСA, while most strains of Streptococcus pyogenes had ALA, less frequently AСA and did not show AIA. We found antibacterial polyresistance in 56.0% of pathogens among the selected strains in the examined patients with CT. A comparative analysis of species antibiotic resistance showed that the largest number of multiresistant strains were S.aureus - 62.0%. The set of revealed persistent properties of chronic tonsillitis pathogens serves as underlying rationale for the search for new methods of therapy using drugs of non-antibacterial origin, affecting the factors of bacteria resistance to inborn and acquired immunity. It is possible, and necessary that attention be paid to phytotherapy in the search for such new methods. Tonsilgon N is one of the complex phytotherapeutic products, which efficacy and safety has been proven in clinical trials, and the main pharmacological properties are confirmed in in vitro and in vivo preclinical studies. It contains marshmallow root, chamomile flowers, horsetail grass, walnut leaves, yarrow grass, oak bark, and dandelion grass. The clinical studies revealed that it has positive effect on the dynamics of both clinical and microbiological, immunological parameters in patients with chronic tonsillitis. All these things allow us to recommend that this complex herbal product be more often included into the comprehensive treatment of chronic tonsillitis. 

IMMUNOLOGICAL CHARACTERISTICS OF THE INFLAMMATORY PROCESS IN THE PULP

2021 ◽  
Vol 2 (1) ◽  
pp. 11-14
Author(s):  
Gilyazeva V.V.
Keyword(s):  
Connective Tissue ◽  
Basement Membrane ◽  
Inflammatory Process ◽  
Pathological Process ◽  
Tooth Pulp ◽  
Pulp Inflammation ◽  
Inflammatory Processes ◽  
Cd 68 ◽  
Main Component

The paper presents the immunological characteristics of the pathological process of the tooth pulp of an inflammatory nature. The content of key markers of inflammatory processes was studied: CD-68, which plays a role in the phagocytic activity of tissue macrophages and type 4 collagen - the main component of the basement membrane of epithelial cells, found in the wall of arterial vessels and the intrinsic substance of connective tissue. An increase in the number of macrophages and a significant increase in the expression of type 4 collagen in pulp inflammation were found. It has been shown that the inflammatory reaction in the pulp is characterized by a sufficient immunological potential for the involvement of a complex of periapical and periradicular tissues in the pathological process and its subsequent long-term completion.

scholarly journals The state of the digestive system in children with systemic connective tissue diseases

2020 ◽  
Vol 65 (1) ◽  
pp. 65-70
Author(s):  
I. D. Chyzhevskaya ◽  
L. M. Belyaeva
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Juvenile Idiopathic Arthritis ◽  
Connective Tissue ◽  
Lupus Erythematosus ◽  
Inflammatory Process ◽  
Digestive System ◽  
Connective Tissue Diseases ◽  
Systemic Lupus ◽  
Juvenile Scleroderma

Purpose. To study the prevalence of the digestive system pathology in children with systemic connective tissue diseases.Characteristics of children and research methods. We carried out a clinical and instrumental examination of 108 children with systemic connective tissue diseases hospitalized in the rheumatology department of the 4th City Children’s Clinical Hospital in Minsk from 2008 to 2015. 60 patients suffered from juvenile idiopathic arthritis (mean age 12.3 [9.4; 15.6] years), 23 children suffered from juvenile scleroderma (mean age 11.8 [9.7; 14.9] years) and 25 children suffered from systemic lupus erythematosus (mean age 13.1 [12.2; 16.3] years). All patients received long-term immunosuppressive and anti-inflammatory therapy.Results. 75.9% patients had gastroenterological complaints, such as abdominal pains, nausea, heartburn. 69.4% of patients had endoscopic changes in the esophagus, stomach, and/or duodenum. According to the results of the morphological study, 43.5% of patients with systemic connective tissue diseases had mild inflammatory process, 29.6% of patients had average inflammatory process, and 3.7% of patients had severe inflammatory process. Among the children examined, 33 (55%) patients with juvenile idiopathic arthritis, 12 (48%) children with systemic lupus erythematosus and 11 (47.8%) patients with juvenile scleroderma were infected with Helicobacter pylori. Pathological changes of the hepatobiliary system and pancreas were diagnosed in 83.3% of children with systemic connective tissue diseases.Conclusion. The revealed changes indicate a probable connection between the pathology of the digestive organs in children with systemic connective tissue diseases and substantiate the gastroenterological examination of this category of patients. 

Prophylaxis of genital prolapse in women in the late postpartum period

2018 ◽  
pp. 31-33
Author(s):  
S.I. Zhuk ◽  
◽  
E.A. Budchenko ◽  
Keyword(s):  
Connective Tissue ◽  
Pelvic Floor ◽  
Key Words ◽  
Postpartum Period ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Genital Prolapse ◽  
Degrees Of Severity ◽  
Female Genital ◽  
Vaginal Cones

The article describes genital prolapse as a pathology of female genital organs. The factors leading to the occurrence of genital prolapse in women of different age groups are presented. Clinical manifestations and mechanisms of their occurrence are substantiated. Considered variants of treatment of women with genital prolapse of various degrees of severity. Illumination of the data of our research of the method of prophylaxis of genital prolapse in the late postpartum period with the help of Corelax vaginal cones. Key words: genital prolapse, rectocele, pelvic floor, connective tissue, vaginal cones.

Continuous Mesothelial Injury and Regeneration during long Term Peritoneal Dialysis

1987 ◽  
Vol 7 (3) ◽  
pp. 148-156 ◽  
Author(s):  
Lazaro Gotloib ◽  
Abshalom Shostack ◽  
Phina Bar-Sella ◽  
Ricardo Cohen
Keyword(s):  
Peritoneal Dialysis ◽  
Connective Tissue ◽  
Peritoneal Fluid ◽  
Mesothelial Cell ◽  
Mesothelial Cells

This study reconstructs the whole sequence of mesothelial injury and regeneration in patients on longterm peritoneal dialysis. Our observations indicate that peritoneal dialysis induces a process of continuous mesothelial injury and regeneration. New mesothelial cells seem to originate from wandering mesothelial cells of the peritoneal fluid, as well as from mesothelial cell precursors localized in the sub-mesothelial connective tissue.

A long-term study of hepatitis B virus-related antigens and immunological parameters in children with chronic hepatitis

Infection ◽  
1984 ◽  
Vol 12 (3) ◽  
pp. 194-196
Author(s):  
Renata Calzia ◽  
Rita Piscopo ◽  
Carla Navone ◽  
Barbara Ciravegna ◽  
S. Raffanti ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Term Study ◽  
Immunological Parameters ◽  
Long Term Study ◽  
B Virus
Sign in / Sign up

Export Citation Format

Share Document