scholarly journals Demodex gatoi infestation in British Shorthair cat treated chronically with immunosuppressive drugs

2017 ◽  
Vol 73 (4) ◽  
pp. 248-251
Author(s):  
Dawid Jańczak ◽  
Elżbieta Gołąb ◽  
Dominika Borkowska-Bąkała ◽  
Karolina Barszcz
Keyword(s):  
Food Allergy ◽  
Immunosuppressive Therapy ◽  
Young Male ◽  
Skin Layer ◽  
Immunosuppressive Drugs ◽  
Hair Follicles ◽  
Diagnostic Process ◽  
The World

To date, only a few cases of Demodex gatoi demodecosis have been reported around the world. D. gatoi is a species of mites that infest cats. The mite is much smaller than D. cati and inhabits the superficial keratin skin layer rather than hair follicles. We describe D. gatoi infestation in a young male British Shorthair cat with pruritic dermatosis treated chronically with immunosuppressive drugs for food allergy. In this report we present the diagnostic process and problems associated with the treatment of D. gatoi infestation in a cat undergoing immunosuppressive therapy

scholarly journals Inflammatory bowel disease and COVID-19: A review

2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Rabin Hamal ◽  
◽  
Rahul Pathak ◽  
Brindeswari Kafle Bhandari ◽  
Anurag Jha ◽  
...  
Keyword(s):  
Immunosuppressive Drugs ◽  
World Health ◽  
Noncommunicable Diseases ◽  
Severe Illness ◽  
Infectious Risk ◽  
The World ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Health Organization ◽  
Chronic Inflammatory Bowel

The World Health Organization officially declared infection with severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), leading to coronavirus disease 2019 (COVID-19) as a Public Health Emergency of International Concern (PHEIC) on 30 January 2020 and then as a pandemic on March 11, 2020 with reports of infection from most of the countries of the world [1]. COVID-19 has severely disrupted prevention and treatment for noncommunicable diseases. Severe illness can occur in otherwise healthy individuals of any age, but it predominantly occurs in adults with advanced age or certain underlying medical comorbidities [2]. Since the beginning of the health emergency, particular attention has been paid to the management of patients with chronic Inflammatory Bowel Diseases (IBDs) because they frequently are treated with immunosuppressive drugs and therefore potentially are exposed to a greater infectious risk than the general population [3].

scholarly journals Immunosenescence as a reason of individualizing immunosuppressive therapy in kidney transplantation

2021 ◽  
Vol 23 (3) ◽  
pp. 171-179
Author(s):  
V. A. Fedulkina ◽  
A. V. Vatazin ◽  
A. V. Kildyushevskiy ◽  
A. B. Zulkarnayev ◽  
D. V. Gubina ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Kidney Transplantation ◽  
Renal Transplant ◽  
Immunosuppressive Therapy ◽  
Immunosuppressive Drugs ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Optimal Balance ◽  
Underlying Diseases ◽  
Adaptive And Innate Immunity

Transplantation in elderly patients is obviously more challenging due to existing underlying diseases, changes in pharmacokinetics of immunosuppressive drugs, polypragmasy, and transformation of immunoreactivity (immunosenescence). Our review presents data on modification of adaptive and innate immunity during aging. It also considers the possibility of both reduced and adapted immunosuppressive therapy in elderly renal transplant recipients in achieving an optimal balance between efficacy and complications.

scholarly journals Improved prospects for food allergy prevention

2017 ◽  
Vol 9 (4) ◽  
pp. 254 ◽  
Author(s):  
Rohan Ameratunga
Keyword(s):  
Food Allergy ◽  
High Risk ◽  
Allergy Prevention ◽  
Window Of Opportunity ◽  
Early Introduction ◽  
The World ◽  
Food Challenges ◽  
High Risk Children

ABSTRACT Three recent publications from Professor Gideon Lack have fundamentally changed our understanding of how to prevent food allergy. His team has shown that early introduction of allergenic foods may prevent food allergy in most but not all high-risk children. Various allergy and paediatric societies around the world are changing their recommendations based on these three studies. It appears there is a window of opportunity to safely introduce allergenic foods to high-risk children. This has resource implications, as some of these children will need testing and food challenges.

scholarly journals Aurea diagnosis of pneumomediastinum. A case report

2020 ◽  
Vol 14 (3) ◽  
pp. 179-183
Author(s):  
Lucio Brugioni ◽  
Francesca De Niederhausern ◽  
Chiara Gozzi ◽  
Pietro Martella ◽  
Elisa Romagnoli ◽  
...  
Keyword(s):  
Emergency Department ◽  
Case Report ◽  
Chest Pain ◽  
Correct Diagnosis ◽  
Young Male ◽  
Differential Diagnoses ◽  
Diagnostic Process ◽  
Acute Aortic Syndrome ◽  
X Ray ◽  
Chest X Ray

Pericarditis and spontaneous pneumomediastinum are among the pathologies that are in differential diagnoses when a patient describes dorsal irradiated chest pain: if the patient is young, male, and long-limbed, it is necessary to exclude an acute aortic syndrome firstly. We present the case of a young man who arrived at the Emergency Department for chest pain: an echocardiogram performed an immediate diagnosis of pericarditis. However, if the patient had performed a chest X-ray, this would have enabled the observation of pneumomediastinum, allowing a correct diagnosis of pneumomediastinum and treatment. The purpose of this report is to highlight the importance of the diagnostic process.

scholarly journals Transient Efficacy of Tofacitinib in Alopecia Areata Universalis

2016 ◽  
Vol 8 (1) ◽  
pp. 102-106 ◽  
Author(s):  
Florian Anzengruber ◽  
Julia-Tatjana Maul ◽  
Jivko Kamarachev ◽  
Ralph M. Trüeb ◽  
Lars E. French ◽  
...  
Keyword(s):  
Treatment Option ◽  
Alopecia Areata ◽  
Kinase Inhibitors ◽  
Autoimmune Disorder ◽  
Immunosuppressive Drugs ◽  
Hair Follicles ◽  
Janus Kinase ◽  
Individual Treatment ◽  
Immune Therapies ◽  
New Treatment

Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and subsequently inhibit further hair growth. Depending on the extent of involvement, alopecia areata can be associated with a dramatic reduction of quality of life. Currently, no targeted treatment option is available, and topical immune therapies or immunosuppressive drugs are typically used with mixed success. Recently, several cases of alopecia areata responding to Janus kinase inhibitors were published. Here, we report on a businessman with alopecia areata universalis who was treated with tofacitinib. We observed initial signs of hair regrowth in the same timeframe as previously reported, but efficacy quickly waned again, leading to renewed effluvium. Thus, even though tofacitinib and ruxolitinib are a promising new treatment option, we have yet to learn more about their potential role in each particular patient's individual treatment strategy.

Report of an International Psychogeriatric Association Special Meeting Work Group; Under the Cosponsorship of Alzheimer's Disease International, the European Federation of Neurological Societies, the World Health Organization, and the World Psychiatric Association

1997 ◽  
Vol 9 (S1) ◽  
pp. 11-38 ◽  
Author(s):  
Barry Reisberg ◽  
Alistair Burns ◽  
Henry Brodaty ◽  
Robin Eastwood ◽  
Martin Rossor ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Current Knowledge ◽  
Work Group ◽  
Treatment Strategies ◽  
Diagnostic Procedures ◽  
World Health ◽  
Diagnostic Process ◽  
European Federation ◽  
The World

Current knowledge with respect to the diagnosis of Alzheimer's disease (AD) is reviewed. There is agreement that AD is a characteristic clinicopathologic entity that is amenable to diagnosis. The diagnosis of AD should no longer be considered one of exclusion. Rather, the diagnostic process is one of recognition of the characteristic features of AD and of conditions that can have an impact on presentation or mimic aspects of the clinicopathologic picture. The present availability of improved prognosis, management, and treatment strategies makes the proper, and state-of-the-art, diagnosis of AD a clinical imperative in all medical settings. Concurrently, information regarding the relevance and applicability of current diagnostic procedures in diverse cultural settings must continue to accrue.

scholarly journals Preventive Tuberculosis Services Reduces the Risk of Local Forms of Tuberculosis Development in Children on Immunosuppressive Therapy: Retrospective Cohort Study

2020 ◽  
Vol 19 (5) ◽  
pp. 346-351
Author(s):  
Valentina A. Aksenova ◽  
Nadezda I. Klevno ◽  
Alexey V. Kazakov ◽  
Dmitry A. Kudlay ◽  
Tatyana A. Sevostyanova ◽  
...  
Keyword(s):  
High Risk ◽  
Immunosuppressive Therapy ◽  
Preventive Treatment ◽  
Immunosuppressive Drugs ◽  
Genetically Engineered ◽  
Medical Documentation ◽  
Recombinant Allergen ◽  
Biologic Drugs ◽  
One Year ◽  
Tuberculosis Service

Background. Long-term immunosuppressive therapy in children (including genetically engineered biologic drugs, GEBD) is associated with a high risk of local tuberculosis (TB) development. Objective. The aim of the study was to examine efficacy of tuberculosis services in children with high risk of developing tuberculosis associated with immunosuppressive therapy.Methods. The study included children at the age from 0 to 17 years on immunosuppressive therapy due to autoimmune disease and who were referred to phthisiatrician consultation. The incidence of TB was estimated one year after in groups receiving preventive TB services (isoniazid and pyrazinamide for 3–6 months) due to the high risk of TB development (contact with TB patients and/or controversial or positive test results with tubercular recombinant allergen) or not receiving such therapy (no indications for preventive treatment, parents’ refusal). The source of any data was medical documentation.Results. Preventive tuberculosis service was performed in 167 (60%) out of 279 children included in the study, 112 children did not receive such treatment (5 cases — parents’ refusal, 107 cases — lack of indications for preventive treatment). TB was detected in 1 (0.6%) child after one year in the preventive treatment group, and in 14 (12.5%) children (p < 0.001) in the group without preventive treatment. Thoracic lymph nodes tuberculosis was diagnosed in 4 (27%) patients among all who has developed TB, tuberculous primary complex — in 3 (20%) patients, focal tuberculosis in 7 (46%) patients, disseminated tuberculosis in 1 (7%) patient.Conclusion. Preventive tuberculosis service reduces the risk of tuberculosis in children on administration of immunosuppressive drugs, including GEBD.

scholarly journals Telecommunications in healthcare: state, problems and prospects of development

2021 ◽  
Vol 270 ◽  
pp. 01039
Author(s):  
Alla. Oshkordina ◽  
Felix Badaev
Keyword(s):  
Medical Care ◽  
Information Technologies ◽  
The State ◽  
Medical Institution ◽  
Diagnostic Process ◽  
Medical Organization ◽  
The World

The authors of the article consider the features and problems of the introduction and implementation of telecommunications technologies in healthcare as one of the effective tools for improving the quality and accessibility of medical care to the population of Russia. The article systematizes and summarizes the information and theoretical material on the state and level of implementation of telecommunications technologies in the world practice. The authors present the results of the analysis of changes in the dynamics of telecommunications technologies used on the basis of a medical institution in the Sverdlovsk region. The main directions and prospects for the development of information technologies in medical organizations in the context of the prevention of coronovirus infection are determined. The authors draw a conclusion about the increase in the level of personification of the therapeutic and diagnostic process in modern healthcare, both on the part of the patient and on the part of the medical organization.

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